Bubalus bubalis (water buffalo): 102397191
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Entry
102397191 CDS
T05912
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04010
MAPK signaling pathway
bbub04020
Calcium signaling pathway
bbub04022
cGMP-PKG signaling pathway
bbub04024
cAMP signaling pathway
bbub04260
Cardiac muscle contraction
bbub04261
Adrenergic signaling in cardiomyocytes
bbub04270
Vascular smooth muscle contraction
bbub04723
Retrograde endocannabinoid signaling
bbub04725
Cholinergic synapse
bbub04726
Serotonergic synapse
bbub04727
GABAergic synapse
bbub04911
Insulin secretion
bbub04912
GnRH signaling pathway
bbub04921
Oxytocin signaling pathway
bbub04924
Renin secretion
bbub04925
Aldosterone synthesis and secretion
bbub04927
Cortisol synthesis and secretion
bbub04929
GnRH secretion
bbub04934
Cushing syndrome
bbub04935
Growth hormone synthesis, secretion and action
bbub05010
Alzheimer disease
bbub05020
Prion disease
bbub05022
Pathways of neurodegeneration - multiple diseases
bbub05207
Chemical carcinogenesis - receptor activation
bbub05410
Hypertrophic cardiomyopathy
bbub05412
Arrhythmogenic right ventricular cardiomyopathy
bbub05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102397191 (CACNA1S)
04020 Calcium signaling pathway
102397191 (CACNA1S)
04024 cAMP signaling pathway
102397191 (CACNA1S)
04022 cGMP-PKG signaling pathway
102397191 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
102397191 (CACNA1S)
04929 GnRH secretion
102397191 (CACNA1S)
04912 GnRH signaling pathway
102397191 (CACNA1S)
04921 Oxytocin signaling pathway
102397191 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
102397191 (CACNA1S)
04924 Renin secretion
102397191 (CACNA1S)
04925 Aldosterone synthesis and secretion
102397191 (CACNA1S)
04927 Cortisol synthesis and secretion
102397191 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
102397191 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
102397191 (CACNA1S)
04270 Vascular smooth muscle contraction
102397191 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
102397191 (CACNA1S)
04725 Cholinergic synapse
102397191 (CACNA1S)
04726 Serotonergic synapse
102397191 (CACNA1S)
04723 Retrograde endocannabinoid signaling
102397191 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102397191 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
102397191 (CACNA1S)
05020 Prion disease
102397191 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
102397191 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102397191 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
102397191 (CACNA1S)
05414 Dilated cardiomyopathy
102397191 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102397191 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
bbub04040
]
102397191 (CACNA1S)
Ion channels [BR:
bbub04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
102397191 (CACNA1S)
BRITE hierarchy
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GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
Motif
Other DBs
NCBI-GeneID:
102397191
NCBI-ProteinID:
XP_006078505
LinkDB
All DBs
Position
5:1362536..1420855
Genome browser
AA seq
1872 aa
AA seq
DB search
MEPAPAQDEGLRRKQAKKPVPEVLPRPPRALFCLTLQNPVRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNRLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNLIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVVIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTISGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLSKVIQFIRHWRQWNRV
FRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKTMVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPEASAFF
IFSPTNKIRVLFHRIVNATWFTNFILLFILLSSAALAAEDPLRAESVRNQILGYFDIGFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPTQIEVRPRQWVHNAFHFDNVLSAMMSLFTVSTFEGWPELL
YKAIDSHEEDKGPVYNHRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYRVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGQLCDPESDYGPGEERTCGTDFAYYYFLSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKVWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDIVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERTNSLAP
HMANQRPLQFTEIEMEEMESPVFLEDFPQRPSTHPLARANTNNANANVASGNSNRGNSPA
FPSVHYEGELARETETPATRGGPFGQPQGALGPHSKSQVEWPQEQLPRRRTPRAQAPAAS
CQHAGAESQVPEERSPIPGSLPGEAPPGSRTEDGTPGGPAPAMALLIREALVRGGLDSLA
ADANFIMATGQALAEACQMEPREVEVAAAELLQGREALEGVPGARGCPGLGSSLDSFDLR
EGSQETLVPRRP
NT seq
5619 nt
NT seq
+upstream
nt +downstream
nt
atggagccggccccggcccaggacgagggcctgcggaggaagcaggccaagaagcccgtc
ccggaggtcctgcccaggccgccccgggccttgttctgcttgaccctccagaaccccgtg
cggaaagcctgcatcagcatcgtcgagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgcgtggccctggccgtgtacctgcccatgccggaggacgacaacaac
agactgaacctcggcctggagaagctggaatacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcctacggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaacgtgctggacttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggtcaacctcattcagagcaacacggccccgatgagcagcaaaggcgcgggcctggac
gtcaaggcgctgcgggccttccgcgtgctccgcccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctgccgctcttccacatcgcc
ctgctggtgctcttcatggtcgtcatctacgccatcatcggcctcgagctcttcaagggc
aagatgcacaagacctgctacttcatcggcactgacatcgtggccacggtggagaacgag
aagccgtccccctgcgcccggacgggctccggccgcccctgcaccatcagcggcagcgag
tgccgtggcgggtggcccggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtgaacgatgccatcgggaacgagtggccctggatctactttgtcaccctcatcctgctg
ggctccttcttcatcctcaacctggtgctgggcgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacacagggcgaggtcatggacgtggatgac
ttgagagaagggaagctggctctggatgaaggcggctccgacacggagagcctgtacgaa
atcgcgggcttgagcaaagttatccagttcatccgacactggaggcagtggaaccgcgtt
ttccgctggaagtgccacgatgtggtaaagtccagggtcttctactggctggtcatcctg
atcgtcgctctcaacacactgtcgatcgcctcagagcaccaccaccagcctctctggttg
acccacctgcaagacgtggccaaccgggtgctgctggccctgttcaccgtggagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcctcttggagatcctgctggtggagtcgggtgccatgacg
cccctgggcatctcggtgctgcgctgcatccgtctgctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcgtcgctgctcaactccatccgctccatcgcc
tcgctgctgctgctgctcttcctgttcatcgtcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacaccgaggtgcggcgtagcaacttcgacagcttc
ccacaggccctcatcagcgtcttccaggtgctgacaggagaggactggaactccgtgatg
tacaacgggatcatggcctatggcggcccatcctaccccggggtgctcgtctgcatttac
ttcatcatcctgtttgtctgcggcaactacatcctgctcaacgtcttcctggccatcgct
gtggacaacctggcagaggccgagagcctgacttctgcccagaaggccaaggctgaggag
cggagacgcaggaagatgtccaagggtctcccggacaagtcggaggaggagaagacgatg
gtggccaagaagctggagcagaaacccaagggggaaggcatccccaccaccgccaagctg
aagatcgatgagtttgaatccaacgtcaacgaggtgaaggacccctacccctcggccgac
ttcccaggggatgatgaggaggacgagcccgaggtcccaataagcccccggccccgaccg
ctggctgagctgcagctgaaggagaaggcggtgcccattccagaagccagtgctttcttc
atcttcagccccaccaacaagatccgcgtcctgttccaccgcattgtcaatgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagcgctgccctggccgccgaggac
cccctccgggctgagtccgtgaggaaccagatcctcgggtattttgacatcgggttcacc
tctgtcttcactgtggagattgtcctcaagatgaccacctacggggccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctggtggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaagatcctgagggtcctgagg
gtgctccgaccgctccgggccatcaacagagccaaaggcctgaagcacgtggtacagtgt
gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaagggcaagttcttcagctgcaatgacttg
tccaagatgacggaggaggagtgcaggggctactactacgtgtacaaagatggagacccc
acgcagatagaggtgcgtccccgccagtgggtgcacaatgccttccacttcgacaacgtg
ctttcggccatgatgtccctcttcactgtgtccaccttcgagggatggcctgagctgctg
tacaaggccattgactctcacgaggaggacaagggccccgtgtacaaccaccgcgtggag
atggccatcttcttcatcatctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggctttgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgtgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccggcccctgaggtgc
tacatccccaagaacccctaccagtaccgggtgtggtacatcgtcacctcctcctacttc
gagtacctgatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcggagcaaatgaaccacatctctgacatcctcaacgtagccttcaccatcatc
ttcacactggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggac
ccctggaacgtgtttgactttctgattgtcatcggcagcatcatcgacgtcatcctcagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggcggctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgccttcttccgcctgttccgtgtc
atgaggctgatcaagctgctgagccgcgcggagggcgtgcgcacgctgctctggactttc
atcaagtccttccaggccctgccctacgtggctctgctcatcgtcatgctcttcttcatc
tacgcggtcatcggcatgcagatgttcggaaagatcgccttggtggacgggacccaaatc
aaccggaacaacaacttccagaccttcccccaggcggtgctgctgctcttcaggtgcgcc
acgggggaggcgtggcaggagatcctgctggcctgcagctacggccagctgtgtgacccc
gagtcggactacggccccggggaggagcgcacctgcggcacggacttcgcctactactac
ttcctcagcttctacatgctgtgcgccttcctgatcatcaacctgtttgtggccgtcatc
atggacaactttgactacctgacacgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatctgggcggagtacgacccggaggctacgggcaggatcaagcacctg
gacgtggtgaccctgctgaggaggatccagcccccgctgggcttcgggaagttctgcccc
caccgggtagcatgtaagcggctggtgggcatgaacatgcccctcaacagtgacggcacg
gtcaccttcaacgccacgctcttcgccctggtgcgcacggctctgaagatcaagacggaa
ggtaacttcgagcaggccaacgaggagctgcgagccatcatcaagaaggtctggaagagg
accagcatgaagctcctggaccaggtcatccctcccataggagatgacgaggtgacggtg
gggaagttctacgccacgttcctcatccaggagcacttccggaagttcatgaggcgccag
gaggagtattatgggtaccggcccaagaaggacatcgtgcagatccaggccggactgagg
accatcgaggaagaggcagcccccgagatccgccgcaccatctcgggagacctgacggcc
gaggaggagctggagagagccatggtggaggccgcaatggaggaagggatcttccggagg
accggcggcctgtttggccaggtggacagcttcctggaaaggaccaactcgttggccccg
cacatggccaaccagagacccctccagtttactgaaattgagatggaggagatggaatcg
cccgtcttcctggaggacttccctcaacgtccgagtacccacccccttgctcgggccaac
accaacaatgcgaacgccaatgttgccagcggcaacagcaaccgtggcaacagcccagca
tttcccagtgtccactacgaaggggagctcgcaagggagacagagacgcctgccaccaga
ggaggacccttcggccagccccagggggccctggggccccacagcaagtcccaagtagag
tggccacaggaacagctgccccggagaaggacgcccagggcccaggcccccgccgcctcc
tgccagcacgcgggagcagagtcccaggtgcctgaggagaggagccccattccagggtcc
ctgcccggggaggcgccgcccggcagtaggacagaggacgggacccctgggggtccagct
ccagccatggccctgctgatccgcgaggctctggttcgagggggcctggacagcttggcg
gcggatgctaacttcatcatggccacgggccaggcgctggcggaggcctgccagatggaa
ccgcgggaagtggaggtggcagccgcagagcttctgcagggacgcgaggccctggagggc
gtgcctggtgcccgagggtgcccaggcctcgggtcctccctggacagcttcgacctgcgt
gagggctcccaggagaccctggttccccgcaggccatga
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integrated database retrieval system
