KEGG   Bubalus bubalis (water buffalo): 102397549
Entry
102397549         CDS       T05912                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04012  ErbB signaling pathway
bbub04020  Calcium signaling pathway
bbub04024  cAMP signaling pathway
bbub04066  HIF-1 signaling pathway
bbub04114  Oocyte meiosis
bbub04148  Efferocytosis
bbub04217  Necroptosis
bbub04261  Adrenergic signaling in cardiomyocytes
bbub04310  Wnt signaling pathway
bbub04360  Axon guidance
bbub04713  Circadian entrainment
bbub04720  Long-term potentiation
bbub04722  Neurotrophin signaling pathway
bbub04725  Cholinergic synapse
bbub04728  Dopaminergic synapse
bbub04740  Olfactory transduction
bbub04750  Inflammatory mediator regulation of TRP channels
bbub04911  Insulin secretion
bbub04912  GnRH signaling pathway
bbub04916  Melanogenesis
bbub04921  Oxytocin signaling pathway
bbub04922  Glucagon signaling pathway
bbub04925  Aldosterone synthesis and secretion
bbub04934  Cushing syndrome
bbub04971  Gastric acid secretion
bbub05012  Parkinson disease
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05031  Amphetamine addiction
bbub05152  Tuberculosis
bbub05200  Pathways in cancer
bbub05205  Proteoglycans in cancer
bbub05214  Glioma
bbub05415  Diabetic cardiomyopathy
bbub05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102397549 (CAMK2A)
   04310 Wnt signaling pathway
    102397549 (CAMK2A)
   04066 HIF-1 signaling pathway
    102397549 (CAMK2A)
   04020 Calcium signaling pathway
    102397549 (CAMK2A)
   04024 cAMP signaling pathway
    102397549 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102397549 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102397549 (CAMK2A)
   04217 Necroptosis
    102397549 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102397549 (CAMK2A)
   04922 Glucagon signaling pathway
    102397549 (CAMK2A)
   04912 GnRH signaling pathway
    102397549 (CAMK2A)
   04921 Oxytocin signaling pathway
    102397549 (CAMK2A)
   04916 Melanogenesis
    102397549 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    102397549 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102397549 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    102397549 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    102397549 (CAMK2A)
   04728 Dopaminergic synapse
    102397549 (CAMK2A)
   04720 Long-term potentiation
    102397549 (CAMK2A)
   04722 Neurotrophin signaling pathway
    102397549 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    102397549 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    102397549 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    102397549 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102397549 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102397549 (CAMK2A)
   05205 Proteoglycans in cancer
    102397549 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    102397549 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102397549 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102397549 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    102397549 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    102397549 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102397549 (CAMK2A)
   05415 Diabetic cardiomyopathy
    102397549 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102397549 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbub01001]
    102397549 (CAMK2A)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     102397549 (CAMK2A)
Protein kinases [BR:bbub01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   102397549 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 Kdo SnoaL_4
Other DBs
NCBI-GeneID: 102397549
NCBI-ProteinID: XP_025148205
LinkDB
Position
9:49582605..49647279
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDESACIAYIRITQYLDASGIPRTAQSEETRVWHRRDGKWQIVHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaactagga
aagggagccttctcagtggtgcgcaggtgtgtgaaggtgctggccggccaggaatatgct
gccaagattatcaacacaaagaagctctcggccagagaccaccagaagctggagcgtgaa
gcccgcatctgccgcctgctgaagcaccccaacatcgtccggctccatgacagcatctct
gaggagggacaccattacctgatctttgacctcgtcaccggcggggagctgtttgaagac
atcgtggcccgggagtattacagtgaggcggatgccagtcactgcatccagcagatcctg
gaggccgtgctgcactgccaccagatgggggtggtgcatcgggacctgaagccggagaac
ctgttgctggcctccaagctcaagggcgctgcggtgaagctggcagactttggcctggcc
atagaggtagagggcgagcagcaggcatggtttgggttcgcagggacacctggatacctc
tccccagaagtgctgcggaaggacccgtatgggaagcccgtggacctgtgggcctgcggg
gtcatcctgtacatcctgctggtggggtaccccccattctgggatgaggaccagcatcgc
ctgtaccagcagatcaaagctggcgcctatgatttcccgtcaccagaatgggacaccgtt
accccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaacgcatc
acggccgctgaggccctcaaacacccctggatctcgcaccggtccaccgtggcctcctgc
atgcatagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaactgaag
ggagccatcctcaccactatgctggccaccaggaacttctctggcgggaagagtggagga
aacaagaagaacgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagcaccaataccaccattgaggatgaagacaccaaagtgcggaaacaagaa
atcataaaagtgacagagcagctgattgaagccataagcaatggagattttgagtcctac
acgaaaatgtgtgaccctgggatgacggccttcgaacccgaggccctggggaacctggtc
gagggcctggacttccatcgattctattttgaaaacctgtggtctcggaacagcaagcct
gtgcacaccaccatcctgaacccccacatccacctgatgggtgacgagtcggcctgcatc
gcctacatccgcatcacgcagtacctggacgccagcggcatcccccgcacggcccagtcg
gaagagacccgcgtctggcaccgccgggatggcaaatggcagatcgtccacttccacaga
tctggggcgccttccgtcctgccgcactga

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