Bubalus bubalis (water buffalo): 102398970 Help Entry 102398970         CDS       T05912                                  Symbol GCK Name (RefSeq) hexokinase-4   KO K12407   glucokinase [EC:2.7.1.2] Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub00010   Glycolysis / Gluconeogenesis bbub00052   Galactose metabolism bbub00500   Starch and sucrose metabolism bbub00520   Amino sugar and nucleotide sugar metabolism bbub00524   Neomycin, kanamycin and gentamicin biosynthesis bbub01100   Metabolic pathways bbub01200   Carbon metabolism bbub01250   Biosynthesis of nucleotide sugars bbub04910   Insulin signaling pathway bbub04911   Insulin secretion bbub04917   Prolactin signaling pathway bbub04922   Glucagon signaling pathway bbub04930   Type II diabetes mellitus bbub04950   Maturity onset diabetes of the young bbub05230   Central carbon metabolism in cancer Module bbub_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bbub_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:bbub00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102398970 (GCK)    00052 Galactose metabolism     102398970 (GCK)    00500 Starch and sucrose metabolism     102398970 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     102398970 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     102398970 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     102398970 (GCK)    04910 Insulin signaling pathway     102398970 (GCK)    04922 Glucagon signaling pathway     102398970 (GCK)    04917 Prolactin signaling pathway     102398970 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     102398970 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102398970 (GCK)    04950 Maturity onset diabetes of the young     102398970 (GCK) Enzymes [BR:bbub01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      102398970 (GCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  102398970 NCBI-ProteinID:  XP_025147150 LinkDB All DBs Position 8:76665524..76702062 Genome browser AA seq 465 aa AA seqDB search MLDDRARMEISKKEKAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHKEASVKMLPT YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTTHQMYSIPEDAMTGTAE MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE LVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK ERFHAIVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctggatgacagagccaggatggagatctccaagaaggaaaaggcggaacagatcctg gcagagttccagctgcaggaggaggacttgaagaaggtgatgaggcggatgcagaaggag atggaccgaggcctgaggctggagacccacaaggaggccagtgtgaagatgctgcccacc tacgtgcgctccaccccagagggctcagaggttggggacttcctctccctggacctgggt ggcaccaacttccgggtgatgctggtgaaggtgggagaaggcgaggcgggacagtggagt gtgaagaccacacaccagatgtactccatccccgaggatgccatgacgggtactgctgag atgctctttgactacatctctgagtgcatttctgacttcctggataagcatcagatgaag cataagaagctgcccttgggcttcaccttctcctttcccgtgaggcatgaagacattgac aagggcatccttctcaactggaccaagggcttcaaggcctcgggagcagaaggcaacaac attgtggggctcctgcgagatgccatcaagcggagaggtgactttgagatggacgtggtg gcaatggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgt gaggttggcatgattgtgggcacgggctgcaacgcttgctacatggaggagatgcagaac gtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggcgccttc ggggactcaggcgagctggacgagttcctgctggagtacgaccgcgtggtggatgagaac tccctgaaccccggccagcagctgtacgagaaactcatcggtggcaagtacatgggtgag ctggtgcggcttgtgctgctgaagcttgtggacgagaatctgctcttccacggagaggcc tcggagcagctgcgcacgcgcggcgccttcgagacacgcttcgtgtctcaggtggagagc gattccggtgaccgcaagcagatctacaatatcctgagcactctagggctgcgaccctcg gccactgactgtgacatcgtgcgccgagcctgcgaaagcgtgtccacgcgcgccgcgcac atgtgcgccgcgggactggcgggcgtcatcaaccggatgcgcgagagccgcagcgaggac gtgatgcgcatcaccgtgggcgtggacggctccgtgtacaagctgcaccccagcttcaag gagcggttccacgccatcgtgcgcaggctgacgcccagctgtgaaatcaccttcattgag tcggaggagggcagcggccggggcgcggccttgatctccgcggtggcctgtaagaaggcc tgcatgctgggccagtaa

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