Bubalus bubalis (water buffalo): 102399433
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Entry
102399433 CDS
T05912
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00140
Steroid hormone biosynthesis
bbub01100
Metabolic pathways
bbub05215
Prostate cancer
Module
bbub_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102399433 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
102399433 (SRD5A2)
Enzymes [BR:
bbub01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
102399433 (SRD5A2)
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Motif
Pfam:
Steroid_dh
Motif
Other DBs
NCBI-GeneID:
102399433
NCBI-ProteinID:
XP_006054831
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Position
12:complement(14167702..14215795)
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AA seq
240 aa
AA seq
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MSVRCQQSPVLAGSATLAALGALVLYLAEPSGYGKYSENLMPVALRLPARAAWFLQELPS
FAVPAGILAGQPSSLLGPPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFSLGIFLFILGMGINIHSDYILRQLRKPGEIIYRI
PQGGLFTYVSGANFLDSTSRCLMTTPSLEEPSFHSSFKETKEQGNKTPTIPLKTIKLLSL
NT seq
723 nt
NT seq
+upstream
nt +downstream
nt
atgtctgttcgctgccagcagagtccggtgctggcaggcagtgccactttggccgccctg
ggggcactggtcctgtacctcgcggagccctccggctacgggaagtactcggagaacctg
atgccggtggctctccgtctgcccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatactcgccgggcagcccagctctctcctgggtccgcctgcg
actgtgcttctgggtctcttctgcgcacattacttccacaggacatttgtttattcactg
ctcactagagggaggccgtttccagtggtattccttttcagaggctttgtcttctgcatg
ggaaatggactcctccaaggctactatctggtctactgtgctgaataccctgctgagtgg
tacacagacatacggtttagcctgggtatcttcttattcattttgggaatgggaatcaac
attcacagtgactatatattgcgccagctcaggaagcctggagaaatcatctataggatt
ccacaaggtggcttgttcacgtatgtttctggagccaatttcctcgattctacctcaaga
tgtttgatgactaccccaagtctcgaagagccctcattccattcatcttttaaagaaacc
aaagaacaagggaacaaaactcccacgatcccgttgaaaaccatcaagctgctgagcctg
taa
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