Bubalus bubalis (water buffalo): 102400136 Help Entry 102400136         CDS       T05912                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub00220   Arginine biosynthesis bbub00330   Arginine and proline metabolism bbub01100   Metabolic pathways bbub04020   Calcium signaling pathway bbub04081   Hormone signaling bbub04145   Phagosome bbub04371   Apelin signaling pathway bbub04713   Circadian entrainment bbub04730   Long-term depression bbub04926   Relaxin signaling pathway bbub04970   Salivary secretion bbub05010   Alzheimer disease bbub05014   Amyotrophic lateral sclerosis bbub05022   Pathways of neurodegeneration - multiple diseases bbub05410   Hypertrophic cardiomyopathy bbub05412   Arrhythmogenic right ventricular cardiomyopathy bbub05414   Dilated cardiomyopathy bbub05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:bbub00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     102400136 (NOS1)    00330 Arginine and proline metabolism     102400136 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     102400136 (NOS1)    04020 Calcium signaling pathway     102400136 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102400136 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102400136 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     102400136 (NOS1)   09154 Digestive system    04970 Salivary secretion     102400136 (NOS1)   09156 Nervous system    04730 Long-term depression     102400136 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     102400136 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102400136 (NOS1)    05014 Amyotrophic lateral sclerosis     102400136 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     102400136 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     102400136 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     102400136 (NOS1)    05414 Dilated cardiomyopathy     102400136 (NOS1)    05416 Viral myocarditis     102400136 (NOS1) Enzymes [BR:bbub01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      102400136 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  102400136 NCBI-ProteinID:  XP_044786077 LinkDB All DBs Position 17:complement(14780411..14903368) Genome browser AA seq 1468 aa AA seqDB search MESHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFSTHLETTFTGDGTPKTI RVTRPLGPPTAAVDLSHQASASREQMLVVDGATGPGNGPQHAPDPGQEAGSLAHANGLAA RPPGQDPAKKSTGVALQGSGENNKLLKEIEPVLNLLTSGGKAINGGGPAKTETKDVEIQV DRDLDGKSHKPLPLGVENDRVFSDLWGKGSMPVVLNNPYSEKEQPPASGKQSPTKNGSPS KCPRFLKVKNWETDVVLSDTLHLKSTLGTGCTEHICMGSIMLPSQQIRKPEDVRTKEQLF PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVW NSQLIRYAGYKQPDGSILGDPANVEFTEICIQQGWKPPRSRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDSSRYNILEDVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRNPNSVH EERKYPEPLRFFPRKGPPLSRGDREVHGLAAVRDSQRRSYKVRFNSVSSYSDSRKSSGDG PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQDLQYQPGDHLGVFPGNHE DLVNALIERLEDAPPANQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPST LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD EVVPCFVRGAPSFHLPQNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVF GCRQSKIDHIYREETLQAKSKGVFRELYTAYSREPDKPKKYVQDILQEQLAEPVYRALKE QGGHIYVCGDVTMAADVLKAIQRIMTQKGKLSVEDAGVFISRLRDDNRYHEDIFGVTLRT YEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4407 nt NT seq  +upstreamnt  +downstreamnt atggagagccatatgttcagcgttcagcagatccaacccaatgtcatttctgtccgcctc ttcaagcgcaaagttgggggcctggggttcctggtgaaggagagggtgagcaagccaccc gtgatcatctctgacctgatccgagggggcgccgcggagcagagcggactcatccaggct ggggacatcattctcgccgtcaatggccagcccttggtggacctgagctacgacagcgcc ctggaggtgctcagggggattgcctccgagacccacgtggtgctcatcctcaggggcccc gagggcttctccacgcacctggagaccaccttcaccggggacgggacccccaagaccatc cgggtgacccggcccctgggtccccccacagcagccgttgacctgtcccaccaagcgtca gccagcagagagcagatgctggtggtggacggggccacaggacccggcaatgggccccag catgcgccagacccggggcaggaagccggctccctcgcccatgccaacggcctggctgcc aggcccccaggccaggacccagccaagaaaagtactggggtcgccctccagggcagcggg gagaacaataaactgctcaaagagatagagcctgtcctgaaccttcttaccagtgggggc aaagcgatcaatggagggggacctgccaagacagagaccaaggacgtggaaatccaggtg gacagagacctggacggcaaatcacacaaacctctgcccctcggcgtggagaacgaccga gtcttcagtgacctgtgggggaagggcagcatgcccgtcgtcctcaacaacccatactca gagaaggagcagccccctgcctcgggaaaacagtctcccacgaagaatggcagcccctcc aagtgccctcgcttcctcaaggtcaagaactgggagaccgacgtggttctctctgacacc ctccacctcaagagcacgttgggaacgggatgcactgagcacatctgtatggggtccatc atgctcccttctcagcaaatacgaaagcctgaagacgtccgcacaaaagaacagctcttt cctcttgccaaagagttcattgatcagtactactcatcaattaaaaggttcggctccaaa gcccacatggagaggctggaagaggtgaacaaagagatcgaaaccaccagcacctaccag ctcaaggacacagagctcatctacggggccaagcatgcctggcggaacgcctcccgctgc gtcggcaggatccagtggtccaagctgcaggtgtttgatgcccgagactgtaccactgct catgggatgttcaactacatctgtaaccacatcaagtatgccaccaacaaagggaacctc agatctgcgatcaccatatttccccagaggaccgacggcaagcacgacttccgcgtttgg aactcccaactcatccgctacgctggctataagcagcccgatggctccatcctgggggac ccagccaacgtggagttcacggagatctgcatacagcagggctggaaacccccacgaagc cgcttcgatgtcctgccgctcctgctccaggcaaacggcaacgacccagagctcttccag atccctccagagttggtgctggaagtccccatcaggcaccccaagttcgagtggttcaag gaccttggactgaagtggtacggcctccctgcagtgtccaacatgctcctggagatcggc ggcctggagttcagcgcctgtcccttcagcggctggtacatgggcacagagattggcgtc cgcgactactgcgacagctcccgatacaacatcctggaggatgtggccaagaagatgaac ttggacatgaggaagacatcctctctgtggaaggaccaggcactggtggagatcaatatt gcagttctgtacagcttccagagtgacaaggtgaccatcgtcgaccaccactccgccact gagtccttcattaagcacatggagaatgaataccgctgccgggggggctgccccgctgac tgggtgtggatcgtgccccccatgtctggcagtatcacccccgtcttccaccaggagatg ctcaactaccggctcacaccctccttcgaataccagcctgacccttggaacacccatgtc tggaaaggcaccaacgggacccccacaaagcggcgagccatcggcttcaagaagctggca gaagccgtcaagttctcagccaaactgatggggcaggctatggccaagagggtcaaagct accatcctttatgccacagagacgggcaagtcgcaggcttatgccaaaaccttgtgtgag atcttcaaacatgcttttgatgccaaggtgatgtccatggaagaatatgacattgtacac ctggaacatgaaactctggtcctggtggttaccagcacctttggcaatggagacccccct gaaaatggggagaaatttggctgtgctctgatggaaatgaggaaccctaactctgtgcac gaggaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctctcc cgtggtgacagagaagtccacggtctggctgcagttcgtgacagccagcgcaggagctac aaggtgcgtttcaacagcgtttcctcgtactccgactcccgcaaatcatcaggtgatggg ccagacctcagagacaactttgagagcactggacccctggccaacgtgaggttctctgtg ttcggccttggctcgcgggcataccctcacttctgcgcctttggacacgccgtggacacc ctcctggaagagcttggaggagagaggatcttgaagatgagggagggggacgagctttgt gggcaggaagaggctttcaggacctgggctaagaaggtcttcaaggcagcctgtgacgtg ttctgcgtgggtgatgacgtcaacatcgagaaggcgaacaactccctcatcagcaatgac cgcagctggaagaggaacaagttccgtctcacctacgtggcggaagctccggaactcaca caaggtctatccaatgtccacaaaaagcgggtctcagccgctcgactcctcagccgccaa aaccttcagagtccaaaatccagtcgatcgaccatcttcgtgcgtctccacaccaatggg agtcaggacctgcagtaccagcccggggaccacctgggcgtcttccctggcaaccacgag gacctggtgaatgccctgatcgagcggctggaggatgccccccctgccaaccagctggtg aaggtggagctgctggaggagcggaacacggctttgggggttatcagtaactggaccgat gagcatcgcctgccgccctgcaccatcttccaggccttcaagtactacctggacatcacc acgcctccgacgccgctgcagctgcagcagtttgcctccctggccaccagtgagaaggag aagcagcgtctgctggtcctcagcaagggtctgcaggagtacgaggaatggaaatggggc aagaaccccactatcgtggaagtgctggaggagttcccgtccatccagatgccctccacc ctgctcctgacccagctgtccctgctgcagcctcgctactattccatcagctcctccccg gacatgtaccccgacgaggtgcatctcaccgtggccatcgtctcctaccgcacccgagat ggagaaggaccaattcaccacggcgtgtgctcctcctggctcaaccggatccaggctgac gaagtggtgccctgtttcgtgagaggagcgcccagcttccacctaccccaaaatccccaa gtgccctgtatcctggttggcccaggcactggcatcgcccccttccggagcttctggcag cagcggcaatttgatatccaacacaaaggaatgagcccctgccccatggtcctggtcttc gggtgccggcagtccaagatagaccacatctacagggaggagaccctgcaggccaagagc aagggggtcttcagagaactgtacacggcctactcccgggagccagacaaaccaaagaag tacgtgcaagacatcctacaagagcagctggcagaacccgtgtatcgagccctgaaggag caagggggccacatctacgtgtgcggggatgtcaccatggcagccgatgtcctcaaagcc atccagcgcatcatgacgcagaagggcaagctctcggtggaggacgctggcgtgttcatc agcaggctgagggatgacaaccgctaccatgaggatattttcggggtcaccctgcgcacg tatgaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaagaaa gacaccgatgaggttttcagctcctaa

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