Bubalus bubalis (water buffalo): 102400189
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Entry
102400189 CDS
T05912
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00562
Inositol phosphate metabolism
bbub01100
Metabolic pathways
bbub04014
Ras signaling pathway
bbub04015
Rap1 signaling pathway
bbub04020
Calcium signaling pathway
bbub04024
cAMP signaling pathway
bbub04070
Phosphatidylinositol signaling system
bbub04919
Thyroid hormone signaling pathway
bbub04933
AGE-RAGE signaling pathway in diabetic complications
bbub05205
Proteoglycans in cancer
Module
bbub_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102400189 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102400189 (PLCE1)
04015 Rap1 signaling pathway
102400189 (PLCE1)
04020 Calcium signaling pathway
102400189 (PLCE1)
04070 Phosphatidylinositol signaling system
102400189 (PLCE1)
04024 cAMP signaling pathway
102400189 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102400189 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102400189 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102400189 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bbub04131
]
102400189 (PLCE1)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
102400189 (PLCE1)
Membrane trafficking [BR:
bbub04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
102400189 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
102400189 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
102400189
NCBI-ProteinID:
XP_006053655
LinkDB
All DBs
Position
23:15617364..15986147
Genome browser
AA seq
2296 aa
AA seq
DB search
MTSEEMAGSVLRPVSQRKVISAQSTVDESNDKVSDINVPKSHPVRRSGETSHTISQPTKL
TEESSGSNMPQIFSVAREKITSDENSNEKCWEKSMPDSVKNLNINCNSILKNHQHGPPQS
QFYETCNSITEEGLCLETGIPSSLEGKVFPGIQLEIDRSPMGMRPLGTQSAIIETSRAHP
ESNMAVFHLRYEVDRRMSDSFCTLSDNLILDDCGNCVLPAVGEEQEKNYMAYTCKLMELT
SNCDKNRQLQCDHCDPLNDKYMCFEGSCPKADVVCSSDSFCREDFTDSPPAKTFLSHFED
FPDNCEEVEEDLFKNKKERSAWLVRRFCKNDKEVKKSVFTGTRAIVRTLPSGHIGLEALS
YIDQKKNGLLLPPERVMERLSTVLVRQDGSQGLSEAQWHPIYSAVRRGEAAEQTIRSLLH
FFAKLPASETAHERISVGPYLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARS
SLLNSFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLKPLIQFPEEVASILME
QEQNIYRRVLPVDYLFFLTRGLGTTERQRSLPCLKASISASILTSQKGEHNALEDLVMRF
NEVSSWVTWLILAAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQ
FMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGAS
GLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSL
ETEEEDSSSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDSHGSEEPQKAFDH
GTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASP
ASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGILDLFSAKAVYMGHPNIDIHTVCVQNK
LSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQH
WLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNPSPGTSAKSAEKPNTLSISNTKK
KKKILMRGESGEVTDDEMATRKAKTHKESRSRSGSDPQDVNEQEESEANAIMNPPNPLPS
RRAHSLTTTGPPTLAAGTASPIRPVSSPVLPASNKSPTSAWNSSGGCPGRIRGGMQGFQS
FMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEAAPLYTNLTIDENIS
GLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGVG
ILQLNDFLVNCQGEHYTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKND
ESQENVKEMQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDD
GMPIIYHGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKTVF
GEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQ
AYNGSNASSPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPK
RIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNA
SGSSRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEDSAFSVNPTTSL
SAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHCACQLLRTYPAATRIDSSNPNPLLFW
LHGIQLVALNYQTDDLSLHLNAAMFEANGGCGYVLKPPVLWDKNCSMYQKFSPLERDLDN
MEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPMWNEQFL
FRVHFEDLVFLRFAVVENNSSVVTAQRIISLKALKRGYRHLQLRNLHNEVLEISSLFINS
RRMEENSSGNTVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGSTKAKQLLQQI
LVMDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGYVG
RIVLKTQQENLEEKSIAQDDKEMLLSSEEDSFFVQVHDVSPEQPRTVIKAPRVSTAQDVI
QQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANRKSSTPKASQRVLLDQECVFQAQSKW
KGAGKFILKLKEQVQASREDKKKGISFASELKKLTKTKQPRGPTSPSQVLASENVQNKEE
KPVGGLPSSDAIDYRQ
NT seq
6891 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcaggttctgttctcagacctgtgagtcagagaaaagtgatc
tctgctcagtcaactgtagatgaaagtaatgataaggtctcggacatcaatgttccgaag
tctcatcctgtcaggcggagtggggagacttctcataccatctcgcaaccgaccaaactt
acagaagaatcttctggaagcaacatgccccagattttctcagtagcaagggagaaaata
accagtgacgagaacagtaatgaaaagtgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacagcatattgaaaaaccatcagcacggccctcctcagagc
cagttttatgaaacgtgcaattctatcacagaggaaggtctgtgtttggaaactggaatc
ccttcttcactggaaggaaaggtgttccctggaattcaactggaaatagacagatctccc
atgggcatgcgtccattaggaactcagtcggccatcatagagacaagcagggcgcaccct
gaaagcaacatggcagtatttcacttgcgttacgaagttgaccgaagaatgtcagacagt
ttctgtaccctgtcagataacttgattttggatgattgtggaaactgtgtactacctgcc
gttggtgaggaacaagagaaaaattacatggcatatacttgcaaactgatggaactgaca
agtaactgtgacaagaataggcagctgcagtgtgatcattgtgaccccttgaatgacaaa
tacatgtgctttgaaggctcttgcccaaaggccgatgttgtatgttcaagtgacagcttt
tgcagggaggattttactgacagtccacctgccaagacctttctgagccattttgaggac
ttccccgataattgtgaagaggtagaagaagatttgttcaaaaataaaaaggagcggtct
gcttggttagtgaggagattttgcaaaaatgacaaggaagttaagaaatctgtgtttact
gggacaagggcaattgtgagaactttgccttctggtcacattggactggaggctttgagt
tatatcgatcagaagaaaaatggtctcttattgcctcctgagagagtcatggaacggctg
tcaacagtgctggttaggcaagatggttcccaaggtctgtcagaagcccagtggcatccg
atctacagtgcagtgagaaggggagaagccgcagaacagacaattagatctcttctccat
ttcttcgccaagctcccagcctccgagacagcccatgaaaggatcagtgtcggtccgtac
ttaaagcaatgtgtccgagacacggtgtgtgagtatcgtgccaccctgcaaaggacttcc
atatctcagtacatcaccggctctctcctggaagccaccacatctttaggagcaagaagc
agcctcctcaattcttttgggggatccacgggacgaatgatgctgaaagaacgccaacca
ggcacctctatggccaactccagtgcccttccttcaagttcagctgggatcagcaaggaa
ctgattgatctgaagcccctcatccagttcccagaggaagtcgccagcattctgatggag
caggagcaaaatatttaccgaagggtcttgccagttgactatcttttcttcttgacccgg
ggcttgggcacaacagaacgccagaggtccctgccctgcctcaaagcatccatctcagca
tccattcttacctcccagaagggagagcacaacgccctcgaagatcttgtgatgagattt
aatgaggtgagctcctgggtgacgtggctgatcctcgcggcgggctccatggaagagaag
cgggaagtcttctcgtacttggttcatgtggccaaatgctgctggaacatgggtaactac
aatgccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcag
tttatggaccagtctgatctggagaccatgaggagcctgaaggacgccatggcccagcac
gagtcttcctgcgagtacaggaaggtggtgacccgagcgctgcacatccccggctgcaag
gtggttcccttctgcggggtgtttctgaaggagctctgtgaggtgctggacggagcctct
ggcctcatgaagctttgcccgaggtacaattcgcaggaagaaactctggagtttgtagcc
gattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaattca
gagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagtctg
gagacagaggaggaggacagctccagtgaagggagcagctcaaggaaaaattccctgaag
gataaagcccgatggcagtttataatcggagatttgttggattctgaaaatgacatcttt
gagcagcccaaagagtgggactctcacggatcggaagagccgcagaaagcctttgaccat
gggacagagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccagttcctg
ttgcagggggccacagtcatccactatgatcaggacacgcacctctctgcccgctgcttc
ctccagcttcagcctgacaatagcaccttgacctggataaaacccaccactgcttcccca
gccagtgctaaagcaaaacttggtgtgctcagtaacacgtctgagcctggcaaattcccg
ttactgggcaatgctggattaagtggcctggtggaggggatcttggatctgttttcagca
aaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaacaaa
ctgagtaacatgtctctctcagagactggtgtgaccctgctctacgggctgcagaccacg
gacaatagattattgcactttgtggcaccaaagcacacagctaaaatgctcttcagtgga
ctgttggagctcacgagagctgtgaggaagatgaggaagttccctgaccaaagacagcat
tggctgcggaaacagtacgtcagcctctaccaggaggatggacgatatgaaggcccaact
ttggctcaagctgtagagctgtttggtggcagacgatggagtactcgaaaccccagccct
gggacatcagcaaagagcgccgagaagcccaacaccttgagtataagcaacaccaagaaa
aagaagaaaatccttatgaggggtgagagtggagaggtgacggacgacgagatggccacc
cgcaaggccaaaacacacaaagagagtcggagccggagcggctctgatcctcaagatgtc
aatgaacaagaagaatcagaggcaaatgccatcatgaaccctcccaaccctctcccttcc
agaagagcccactccttgaccacgactggaccccctaccttggctgccgggacagcatct
cccatcaggccagtgtcctcccctgtgctgcctgcttccaacaagagcccaaccagtgct
tggaacagcagcggcggctgtccagggaggatcagaggagggatgcagggctttcagagc
ttcatggtttcagacagcagcatgagtttcgtggaatttgttgagctgttcaagtcattc
agtgtgaggagccgcaaggacctgaaggacctctttgacatctacgccgtaccctgtgac
cgagctggctctgaggcagcccccctctataccaacctgaccattgacgaaaatatcagc
ggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttgggattattcatc
aagagtaaacagcagctgtctgacaaccagaggcagatatctgatgccattgctgctgcc
agtattgtgacaaatggcaccggggtggagagcacatctctgggtgtgtttggagttggc
atcctccagctcaatgatttcctagtgaattgccaaggagaacactatacttatgatgaa
atcctcagcattatccagaagttcgagcctagcgttagtatgtgtcatcaaggcctaatg
tcatttgaaggatttgcgaggtttctaatggataaagataattttgcctcgaaaaatgat
gagtcacaggagaacgttaaagaaatgcagctgcccctctcctactattacattgaatct
tcacacaatacctacctcacgggccatcagctcaaaggagaatcctcagtagaactctac
agccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggacggagatgat
ggaatgcccatcatttatcatggacacaccctgacaaccaagatccccttcaaggaagtg
gttgaagccatcgatcgcagtgccttcatcacctctgacctgcccatcatcatatcaatt
gagaaccactgttcactgcctcagcaacgaaaaatggcagaaattttcaagactgtgttt
ggagaaaaactggtggctaaattcttatttgaaagtgatttctcagatgatccaatgctc
ccctcgcctgaccaactcagaaggaaagtgcttctcaaaaataagaaattaaaagcccat
cagacaccggtggatatcttaaagcaaaaggctcatcagctagcatccatgcaagctcag
gcttataatggtagcaatgccagctccccacctgctaataatgaggaagaggaagatgaa
gaggatgaatatgattatgattatgaatccctctctgatgacaacattctagaagacaga
cctgaaaataaatcatgtaatgacaaacttcagtttgagtataatgaagaaatccccaag
aggataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgacatggaactg
ggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagagctt
tctgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactctaaatgca
tctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccg
ggcagaatgagccccggggagacagcaccatttaacaaaacatctggaaaaagttcctgt
gaaggaatgcgacaggcctgggaggactctgctttctccgtcaacccaaccacgtccctc
agcgctatcattagaactcccaaatgctaccatatctcctcactgaatgaaaacgccgcc
aaacgtctgtgtcgcaggtattctcagaaactgatccagcactgcgcctgccagctgctg
cggacgtacccggctgccacccgcatcgactcctccaaccccaaccccctcctgttctgg
ctccatgggatacagctcgtggcactcaactaccagacagatgatctctctttacattta
aatgccgccatgtttgaggccaatggtggttgcggttatgttctgaaacccccagttctg
tgggacaagaactgttccatgtatcagaagttctcccccttggaaagagacctggacaac
atggagcctgccatctattctttaactattgtctctgggcagaacgtgtgcccgagtaac
agcacggggagcccatgtatcgaagtcgacgtcctgggcatggccctggacagctgccac
ttccgcacgaagcccatccaccgcaacactctgaaccccatgtggaacgaacagttcctt
ttccgggttcacttcgaagatctagtatttcttcgttttgctgtcgtagagaacaacagc
tcggtggtcactgctcagagaatcatctccctcaaggctctaaagcgaggatatcgacat
cttcagctgcgaaatctccacaatgaagtcttggaaatctctagtttattcataaacagc
aggaggatggaagaaaattcttctggcaatactgtgccggcctctctgatgtttaataca
gaagaaagaaaatgtttgcagactcacagagtcacagtgcatggcgtcccaggcccagag
ccctttactgttttctctataaacggaagcactaaggcaaagcagcttctccaacaaatt
ctcgttatggatcaagataccaaacctattgccacagactattttttaatggaggaaaaa
tatttcatatctaaagagaagaatgaatgtaggaaacagccgttccagagagccattggt
ccagaagaagagatcgtgcagattttaagcagctggtttccagaagagggctatgttggc
aggattgtcttaaaaacccagcaggaaaacctggaagagaagagcattgcacaagatgac
aaggagatgctcctgagctcagaggaggacagcttctttgtccaagtgcatgacgtctcc
ccagagcaaccgcgcacggtcatcaaagcgccgcgtgtcagcaccgcgcaggacgtcatt
cagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccgagt
gactatgtgcttctggaagaggtggtgaaagacaccgccaacaggaaatcttccacccca
aaggcctcccagcgcgtccttttggatcaggagtgtgtgtttcaagctcaaagcaagtgg
aaaggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatctcgagaagat
aaaaaaaaaggcatctcttttgcaagcgaactcaagaagctcaccaagactaaacagccc
cgaggacccacatcaccttctcaggtcttggcctcagaaaacgtccaaaacaaggaagag
aaacctgtgggtggcttgccttccagtgacgccatagactaccgacagtga
DBGET
integrated database retrieval system
