Bubalus bubalis (water buffalo): 102400733 Help Entry 102400733         CDS       T05912                                  Symbol APOB Name (RefSeq) apolipoprotein B-100 isoform X1   KO K14462   apolipoprotein B Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub04975   Fat digestion and absorption bbub04977   Vitamin digestion and absorption bbub04979   Cholesterol metabolism bbub05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bbub00001]  09150 Organismal Systems   09154 Digestive system    04975 Fat digestion and absorption     102400733 (APOB)    04979 Cholesterol metabolism     102400733 (APOB)    04977 Vitamin digestion and absorption     102400733 (APOB)  09160 Human Diseases   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102400733 (APOB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:bbub04147]     102400733 (APOB)    00536 Glycosaminoglycan binding proteins [BR:bbub00536]     102400733 (APOB) Exosome [BR:bbub04147]  Exosomal proteins   Exosomal proteins of other cancer cells    102400733 (APOB) Glycosaminoglycan binding proteins [BR:bbub00536]  Heparan sulfate / Heparin   Others    102400733 (APOB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Vitellogenin_N Vit_open_b-sht DUF1081 ApoB100_C Motif Other DBs NCBI-GeneID:  102400733 NCBI-ProteinID:  XP_044782143 LinkDB All DBs Position 12:77488978..77530867 Genome browser AA seq 4575 aa AA seqDB search MGAPRPAVLLLLLLLFLDAASAQARDEVLENVSPSCPKDATRFKHLRKYVYNYEAESSSG VPGTADSRSATKINCKVELEVPQLCNFILKTSDCTLEEVDGLNPEGKALLKKTKNSEEFA AAMSKYDLKLAVPEGKQVLLYPEKEEPKHILNIKRGIISALLLPPETEEAKQVLFLDTVY GNCSTDFTVKTKKGNVATEISIERNLEKCDHFQPISTGVSPLALIRGMTRPLSTLIGSSQ SCRYTLDPRKKHVSEAICNEQHLFLPFSYKNKYGMMAQVTQTLKLENTPKINSRFFEEGT EAVGLAFESTRSTSPPNHAEAIVKTLQELQKLHVSEQNAQRANLFHKLVTELRGLSSEAV TSLLPKLIEVSSPITLQALIQCGQPQCYTHILQWLKTERANPLLIDAATYLVALIPEPSA ERLREVFNTARVQQSRLTFYALSHMINNYHKTNPTRTQDLLEIADYLSEQIGSDCTGNED LTYLILRVIGNIGKTMEQLTPKLTSSVLKCIRSERPSLVIQKAAIQALRKMELSDEVREV LLQTFLDDTSPGDKRLAAYLMLMGSPSQSDISKITQLLPREQNEQVKNFVASHIANILNS EDLSVQDLKSLVEEALKKSQLPTIMDFKKFSRSYQFSKSISLPSLDLVSTKIEGNLIFDP NNYLPKESMLKTTLKVFGFASADLFEIGLEGKGFEPTLEALFGKEGFFPDSVNKALYWVN GRVPDHVSKVLVDHFGYTKDDKHEQDMVNGIMFNVEKLVKDLKSKDFPEARAYLRILGEE LGFVKLHDLQLLGKLLLKGVRTLQGIPQMIKELIRKGSASDLFLHYVFMDNAFELPTGLG LQLQVSSSGVITPGIKAGVKLEVADMQAELVTKPSVSVEFVTNMGIVIPDFARSGVQMNT NFFHETGLEARVVLKAGQLKFIIPSPKRPVRLFSGSSNTLHLVSTTKTEAIPPLIENRQS WSTCKPFFIGLNYCITGAYSNASSTDSSSYYPLTGDTRFELELKPTGEVEQYSAKAFYEL RRDDEALVDMLKLVTQTEGVKQTEATLLFRYNRQSKTLSSELHIPDFDVDLGTVLKVNYE HSKEKKSYKLTLDFQNKKITEVTLTGHISYDRREEGKIKGVISIPRLQAEARSEILSLWS PSKLLLQMDSSATAYGSTISKKVAWRYDGDKIEFEWNTGTNVDTKKATSNFPVDLSGFPK SLHTYANILLDRRVPQTDLTFRHMGSKLVAAASTWLQETSRSLPYAQNIQDQLNGLQELC LQKMELPDFHIPDNLFLKSDGRIKYTLNKNSMEIEIPLPFGGKSSEDLKMFKTIQTPALN FQPLGFHLPSQEFQIPTFTIPNLYPLRLPLLGVLDLSTSIYSNLYNWSASYTGGNTSTDH WSLQAQYHVKADSVVDLLSYHVQGSGKTAYDHRNTLTLSGDGSLHHKFLDSNVKFSHVEK RGNSPASEGLLTFDASSAWGPQISASVHLDSKKKEHLYVKEVKIDGQFKASAFYVKGAYD LSYQRDPATGQLTGESNLRFNSSYVQGTNQITGRYDDGTVSITSTSDLQDGLVKNTASLK YENYELTLKSDTNGKYEDFATSNKVDLTFSKQNALLRSEYQADYKSLRFFTLLSGSLNSH GLELNADILGTDKINSGAHKATLRIARDGMSTSATTSLKYSPLVLENELNAAVSLSGASL KLTSNGRFREHHAKFSVDGKAAPTEVSLGSAYQAMILGVDSKNIFHFKINQEGLKLSNDI MGSYNEMKLDYTNNLNVVGFSLDFSSKLDNIYSSDKFYKQNFNLQLEPYSLVTTLNSDLK FNALDMTNNGKLRLEPLKLNVGGTIKAAYQNDEIKHIYTLSYADLSASYKADTVAKVQGI EFSHRLNTNIAGLASTVDISTNYNSDSLHFSNSFHSAVAPFTMTIDTHTNGNGELVLWGQ HTGQLYSKFLLKAEPLAFTFSHDYRGSTSHRLMSKRSITTALDHKVSALLTLAEQTGDWK LRTRLNQNEYSQDFSAYNTRDKVGVELSGRALADLTVLDFPIAVPLVLRESINVIDTFEM RDSVGQPQEFTLVASVKYDKNQNAHAIHLPFFKFLPKYFEKTRVVVIGALEAVQKELKRT HIDKHMRKYIAALDRLSQQVSDYLSTFNWERQVLSAKEKLTAFTENHRMTENDLQIVLDN AKINLNEKLSQLQTYVIQFDQYIEDNYDLHDFKTTIAKIIDQIIEKLKILDEHYHIRVNL VKKIRDLYFFIENFDFNKIGSSTASWIQNMDTKYQIRIQIQEKLQQLKVQIQTVDIHHLA EMFKQQVEAVDVRVLLDRLRTTIPFQRIKEIIEHVKYRVTSLSEGFKVTEEINAFRVMVH EFIKMYKIDQHIQALMDKSVQLAQQYKLQETVQKLSSVLQQVKMAEIVEKLIGLTDNALK QLEALSFNQFLEEVNRFLDMLVKKLRSFDYHQFVDETNNKIHEVTQRINDEIQALELPQK AKALRLLVEDARIVVSTYLENLKATKITLVLDWLQEALSSTSVTYMKAKFQETLEDFRDR VYQMDVRQELQRYLFLVGQVYNTLVTYISDWWALAAKNLTDFAEQYSIQDWAENLKTLVE QGFTVPEIQTTFGTIPAFKIGLRALQEATYQTPDFIVPLTDLRIPSFQINFKTLKDVKIP SSFSTPEFTILNTLHIPSFTIDFVEIKIKIVRTIDQMLNSELQWPVPEVYLGDLSGVDTI LAGITVPDFHLPEITIPEFVIPNLNLTDFQVSDLHIPEFQLPHISHTIEVPAFGKLYSIL KIQSPFFTLDANADIQNATALANQAEIEASITAKGASRLEVLNFDFQAKAQLLDPTINPL VLKESVRFSSKYLKTEHESEVLWVGNAIEGKSNTVAGIHTEKNTLELSSSVLININNQLT LDSNTKYFHKLNIPQLDFSSQADLHSDLKTLLEAGHIAWTSSGRASWKLACHEFSDEGTH ESQSSFTVEESITSFRLSNKINSKHLRVNQKILYESRFLNFSKFEIQSQAECQHVGRSVL TAKGLALLQEGKAEITGNHDAHLNGKVVGTLRNSLFFSAQPYEMTASTNNEGNLRVSFPL KLTGKIDFLNNYALFLSPSTQQASWQASGRFNQYKYHQNFSAGNNEKSIEAHIGINGEAN LDFLNIPLTIPEMTLPYTKLTTPQIKEISLWKKTGLKDFLKTTKQSFDLSVRAQYKKNKD KHSIPVPLDAFYALIHRNINSFSRLFETVRNQALDFFIKSYNEAKTTFDKYKVEKSLNQQ PKIYKIPGYTIPVANIEVSPFTVKMLTFEYMIPREISTPSITVLGSGISVPSYTLALPFL ELPALRVPKELSELSLPEFKVLSTINKILIPALGNITYDFSFKSSVITLNTNVGLYNQSD IVAHFLTSSSSVMDALQYKLEGTSSLTRKRGLKLATALSLSNRFVEGNHDSTVSFTKKNM DASVTTTARVQIPILKMSFKQELHGNTKSKPTVSSAIELKYNFNSPKLLSAATGAVTHKL TLESFTSYFSIESSTKGGVEGSFGSWGYSGSLASEASTYLNSKGTRSSVTLQGDSKADGL WDLKVKENFAGEATLQRIYTIWEQNMKSHLELGGLILTSGEHTSKATLELSLWKISALVQ VRAHQPSSLLKINFLGQEVSLNVNTENQKISWNSEVQVHSGSLQNNIQLSNDQEVARFDM AVSLEGYLRFLKDTVLPVYDKSLWDLLKLNVTTSLNRKQYLRAATALIYTKNPNGYLVSI PVQELNDKFIIPGLKRNNQNSVHVTPTFQVPFTDLQVPSYTLDLSEIKIYKKLSTLPLTF NVSTLPKVKFPRVDVLIQYSKPEASSVPFFEITVPASQLTVSQFTLPKSISVGSTVLDLN TVASNIADSELPTITMPEQTLEIPSMKFSVPAGILVPSFGTLTARFEVASPLYNTTWSAG LKNKGDHVETFLDSTCSSTIQFLEYDLNVVGTHKIEGGMLVCKTNASFAHRDFSAEYEED GKYQGLGYWNGKVDLNITSPTLTDVRLHYQENENHFSSSVASPAIGTVVIDVKNISDTVL GWNLYYRPQASPDKILNIFKTELRVLELDDEIQIKANWEEGAVSELLSSLKDSVPRATGA LYDYVNKYHQEYTGLDLKDASLKLRRGLQDSADQVYQGAMRQIDEVDMELQRMARGTTET YLQWKDKAQSLYQELLAQEDRSGFQRLQKKVSDSLIGVTQRYSVTVKHATDLLIDLLNVT RFQLPGRARNYTADELCTVVIQEIAKRLSQVHSNIHKGLHILFSYLLYLMEESELYKDLN NKFSFTSMCNQLIDMVLECMKTFLFFSQEIQKALSYLQSTMMTEMLSDLQRSLQDIFQEI ESELKRFKEKKLTDFINQTLQNINTISDIYISFVFRFLKENLGYNFVEFNELIQNKLQVA SQELQQLLQYVQALHQEYFDPTTVGWTVKYYEFEEKIINLIKNLVDVLKDFHSKYIVGAT DFASQLSSQIEPLIQKSLQEYLSILANAEGRGKEKITELSTSAQEVIKSWAVAVKEIISD YHQQFTYKLQEFSDQLSDYCEKFISESKRLIDLSSQNYHMFLNYIMELLKELQSATVNDM SPYIKVAPGEFTITF NT seq 13728 nt NT seq  +upstreamnt  +downstreamnt atgggcgccccgaggcccgcggtgctgctgctgctgctgctgctgttcctggatgccgcc agcgcccaggccagagatgaagtgctggaaaatgtcagccccagctgtccaaaagatgca acgcgattcaagcacctcaggaaatatgtctataactatgaggctgagagttccagtggt gtccctgggactgctgattcaagaagcgccaccaagatcaactgcaaggtggagctggag gtcccccaactctgcaacttcatcctgaagacgagtgactgcaccctggaagaggtggat ggcctcaaccctgagggcaaggccttgctgaagaagaccaagaactctgaggagtttgct gctgcgatgtccaagtacgacctcaagctggctgttcctgaaggcaagcaagttctactt tatccagagaaagaagagcctaaacacatcctcaacatcaagaggggcatcatctctgcc ctcctgcttcccccagaaacggaagaggctaagcaagtgttatttctggataccgtgtat ggaaactgctccacagactttactgttaaaacgaagaagggaaacgtggcaacagaaata tctattgaaagaaacctggagaagtgtgatcacttccagcccattagcacgggagttagc ccactcgctttgattagaggcatgacccgccccttgtcaacactgattggcagcagccag tcctgccggtacaccctggacccaaggaagaagcacgtgtcagaagccatctgcaatgag caacacctattcctgcccttctcctacaagaacaaatacgggatgatggcacaggtcaca cagactttgaaacttgaaaacacacctaagatcaacagccgcttctttgaggaaggcact gaggcagtgggtcttgcctttgagagcaccaggtccacgtcacctccaaaccacgctgag gccattgtgaagacactccaggagctgcagaaactgcacgtctctgagcagaatgcccag agagccaacctcttccataaactagtgaccgagctgcgaggcctcagcagtgaggcggtc acctccctcttgccgaagctgatcgaggtgtccagccccatcactttacaagccttgatt cagtgtggacagccccagtgctacactcacatcctccagtggctgaaaactgagagagcc aacccccttctgatagacgccgcgacctacctggtggccctaatcccagagccctcggcc gagaggctgcgggaggtctttaacaccgcaagagtgcagcagagccggctcacgttttat gctctgagtcacatgatcaacaactatcataagacaaaccctacacggacacaggacctg ctggaaattgctgattacctgtcagaacagattggcagtgactgcactgggaacgaagat ctcacctacctgattctgagggtcataggaaatattggtaaaaccatggagcaactaacc cccaaactcacatcttcagtcctgaaatgtatcagaagtgaacggccatccctggtgatt cagaaggctgccatccaggccctgaggaaaatggagcttagtgacgaggtccgggaagtc ctccttcagactttcctcgatgacacctctccaggggataagcggctggctgcctatctc atgctgatggggagtccttcccagtcggatattagcaaaatcacccaacttctccctcgg gaacagaatgagcaagtgaagaactttgtggcttcccacatcgccaacatcttaaactca gaagatttgtctgtccaggacttgaaaagcttagtggaagaagctctgaaaaaatctcag cttccaactatcatggatttcaagaaattttcccggagctatcagttttccaaatcaatt tccctgccatcacttgacctggtctcaaccaaaatcgaaggaaatcttatatttgatcca aacaattaccttcctaaagaaagcatgctgaaaacgaccctcaaagtctttggatttgct tcagctgacctctttgagattggtttggaaggaaaaggttttgaaccaacacttgaagct ctttttgggaaggaaggatttttcccagacagtgtcaacaaggctttgtactgggttaac ggtcgagttcctgatcatgtctccaaggtcttggtagaccactttggctacaccaaagat gataaacatgagcaggacatggtcaatggaatcatgttcaacgttgagaagctggtcaaa gatctgaaatccaaagacttcccagaagccagagcctacctccgcatcttgggagaagag cttggctttgtcaaactccacgacctccaactcctggggaagttgctgctgaaaggtgtt cgtaccctgcaggggatccctcagatgattaaagagctcataaggaaaggttcagcaagc gacttgttccttcactacgtcttcatggacaacgcctttgaactccccactggacttgga ttacaactgcaagtgtcctcctccggcgtcatcacgcctggaatcaaagctggagtgaaa ctggaagtagctgatatgcaggcagaactggtgacaaagccgtctgtgtctgtggagttt gtgacaaacatgggcatcgtcatcccagactttgccaggagcggggtgcagatgaacacc aacttcttccatgaaacaggcctggaggcacgagtagtcctaaaagccgggcagctgaag ttcatcattccttctcccaagaggccagtcaggctgttcagtggcagtagtaacacattg catttggtctctaccaccaaaacagaagcgatcccacctctcattgagaacaggcagtcc tggtcaacttgcaagcctttcttcattggcctgaactattgcatcacgggtgcttactcc aatgccagctccacagactcttcctcctactacccgctgactggggacaccagatttgaa ctggaattgaaacccacaggagaagtggaacagtattctgccaaggcattctatgaactg cggagagatgatgaagccttggtggacatgctgaagcttgtaactcagactgaaggtgtg aagcagaccgaggctactctgctgtttagatacaaccggcagagtaagaccttgtccagt gaactccacattccagattttgacgttgaccttgggacagtcctcaaagttaattatgaa cattctaaggaaaagaagtcttacaagctcaccctggactttcagaacaagaaaatcact gaggtcaccctcactggccacataagctatgacaggagggaagaaggcaaaatcaaaggt gtgatttccataccccgtttgcaagcggaagccagaagtgagattctcagcctctggtct ccctcaaaactgctccttcagatggactcctctgccacggcttacggctcaacaatatcc aagaaggtggcgtggcgttatgatggagataagattgaatttgaatggaacacaggcacc aatgtggatactaaaaaagcaacttccaatttccctgtggatctctctggttttcctaaa agcttgcatacatatgccaatattctcctggatcgccgagttcctcagacagacctgact tttcggcacatgggttccaaattagttgctgcagcaagcacctggctccaggagacatcg aggagtcttccttatgcccagaatatacaagatcaactcaatggcctgcaagagttgtgc ctccagaaaatggaattgccagacttccacatcccagacaacctcttcttgaaaagtgac ggtcggatcaaatacaccttgaacaaaaacagtatggaaattgagatcccattgcctttt ggtggcaaatcctccgaagatctaaagatgttcaagacgattcagactccagccctcaac ttccagcctctgggattccacctgccatcgcaagagttccaaatccccacttttaccatc cccaacttgtatccactgcggctgcccctcttgggtgtgctagacctctccacaagtatc tacagcaacttgtacaactggtctgcctcctatactgggggcaacaccagcacagaccac tggagccttcaggctcagtaccacgtgaaggcagattctgtggttgacctgctctcctac cacgtacaaggatctggaaaaacagcgtatgaccacaggaatacactcaccttatcaggt gatgggtctctacaccacaaatttctggattcaaatgtcaaattcagtcacgtagagaaa aggggaaacagtccagcctcagaaggtctgctaacatttgacgcatccagtgcctggggc ccacagatttctgcgtcagtccatttggactcaaagaagaaagagcatttgtacgtcaag gaagtcaagattgacggacagttcaaagcctctgcattctatgttaaaggcgcatatgac ctgtcttatcagagagatcctgccacgggccagctcactggagaatccaacctgaggttt aactcctcctacgtccagggcaccaatcagataacaggaaggtacgatgatggcactgtc tccattacctccacctcggatctgcaagatggcctcgtgaaaaatactgcttccctgaaa tatgagaactatgagctgaccctgaaatctgacaccaacgggaagtatgaggactttgcc acttcaaacaaagtagatctgaccttctctaagcagaatgcattgctccgttctgagtat caggctgattacaagtcactgaggttcttcaccctgctttctggatctctaaattctcac ggccttgagttaaatgctgatatcttgggcactgacaagattaatagtggcgctcacaag gcaacactcaggattgcccgggacggaatgtccaccagtgcgacaaccagcttgaagtat agtcccctggtgctggagaatgaactcaacgcagcagtcagcctctctggggcatctctg aaattaacatcaaacggccgctttcgagaacaccatgcgaaattcagtgtagatggaaaa gctgcccccacagaggtgtcactgggaagtgcttatcaggccatgattctgggtgtcgac agcaaaaacatcttccacttcaaaatcaaccaggaaggactcaagctttcaaatgacata atgggttcatataatgaaatgaaacttgactacacaaacaatttgaacgttgtagggttc tcactggacttctcttccaaacttgacaacatttatagctctgacaagttttataagcaa aattttaatctacagttagagccctattccctggtaactactttaaacagtgacttgaaa ttcaatgctctggatatgaccaacaatggaaaattaaggctagaacctctgaagctgaat gtgggtgggaccataaaagcagcctaccaaaatgatgaaataaaacacatctacactctt tcttatgctgacttatctgcaagctataaagcagacactgtagctaaggtacagggaata gagtttagccatcggctcaacacgaacattgctgggcttgcttcaactgtggacatcagt acaaactacaactcagactccctgcatttcagcaattcattccactctgcagtggcccca tttacaatgaccatcgacacacatacaaatggcaatggggagctggttctctggggacaa cacacggggcagctgtacagcaaattcctgttgaaagctgaacctctggcctttactttc tcccatgactacagaggatccacaagtcaccgtctcatgtccaagaggagcatcaccact gctcttgatcacaaagtcagtgccctactcactctggccgagcagacaggcgactggaaa ctcaggacccggttgaaccaaaatgaatacagccaggacttcagtgcttacaacacaaga gacaaagttggtgttgagctcagtggacgagccctggctgacctcactgtgctggacttc cctattgcagtgccacttgtactcagagagtccatcaatgtcattgacactttcgagatg agagattctgttggccagccccaagaattcactcttgttgcttctgtaaaatatgataag aaccaaaatgctcacgccatccatctcccattctttaaattcctgccaaaatattttgag aagactcgggtcgtagtcataggtgcactggaggctgtacagaaagaattgaagcgcacc catattgataaacacatgaggaaatacatagcagccttggacagactctcacagcaagtt agtgattatctgagcacgttcaattgggagagacaagttttgagtgccaaggagaaacta actgctttcacagaaaatcatagaatgacagaaaatgacctgcaaattgtattagacaat gccaaaatcaaccttaatgaaaaactgtctcagctgcaaacatatgtgatacaatttgat cagtatattgaagataattatgatttgcatgattttaagacaactattgctaagattatt gatcaaatcattgaaaaattgaaaattcttgatgaacattatcatatccgtgtcaattta gtaaaaaaaatccgtgatctgtatttttttattgaaaattttgattttaacaaaattgga agtagtactgcatcttggattcaaaatatggatactaagtatcaaatcagaatccagata caagaaaaattgcaacagctcaaggtacagattcagactgtagacatccatcaccttgct gaaatgttcaaacagcaggttgaagctgttgacgtcagagtgcttttagatcggttgaga actacaatcccatttcaaagaataaaggaaattattgagcatgtcaaataccgtgttaca agtctttctgaaggttttaaagtaactgaggaaatcaatgctttcagagtcatggtccat gagttcattaagatgtataaaatagatcaacacatccaggctttaatggataaatcagtg cagttggcccaacaatataagctgcaggagactgttcagaagctaagcagtgtcctacag caagtcaagatggcagaaattgttgaaaaattgattgggcttaccgacaatgctctcaag cagcttgaagcattgtcttttaatcaattccttgaagaagtaaacagattccttgacatg ttggtaaaaaaattaaggtcatttgattaccaccagtttgtagatgaaaccaataacaaa attcatgaagtgactcagcgaatcaatgatgaaattcaggccctggaactcccacagaaa gcaaaggcactcagactgcttgtagaggatgctaggattgtggtctcaacctatctggaa aacctaaaggccaccaaaatcaccttagtcttggattggttacaggaggctctaagttca acatctgtaacttacatgaaagcaaagtttcaggagaccctggaagattttcgagaccga gtatatcaaatggatgtacggcaggaactccagcggtacctattcctagtgggccaggtc tacaacacactcgtcacctacatttctgactggtgggctcttgctgctaagaaccttact gactttgcagaacagtattcgatccaagactgggctgaaaacctgaaaacgttagtagaa caagggttcactgttcctgaaatccagaccacctttgggaccatacctgccttcaaaatc ggtctccgtgcccttcaggaggctacataccagactcctgacttcatcgttcccctgaca gatctgaggatcccatcctttcagatcaacttcaaaacactgaaggatgtgaaaatcccg tccagcttttccacaccagaatttaccatccttaataccctccacatcccttcctttaca attgacttcgtagaaataaaaataaagatcgtcagaaccattgaccagatgctgaacagt gagctgcagtggccagtcccggaagtgtacctgggggatctgagtggggtggataccatt cttgctggaatcactgtgccagacttccatttacccgaaatcactattccagaatttgtc atcccgaatctcaaccttacagattttcaagtttctgaccttcacatcccagaattccag cttccccatatctcacatacaattgaagtacctgcttttggcaagctgtacagcattctg aaaatccagtctccttttttcacattagatgcaaatgctgacattcagaatgcaacagct ttggcaaaccaggcggagatcgaggcttccatcaccgccaaaggagcatccagattagaa gtgctcaattttgattttcaagcaaaagcacaacttttggaccctacaattaatccactg gttctgaaggaatctgtgaggttctccagcaagtacctgaagacagagcatgagagtgag gtgctctgggttggaaatgctatcgagggaaagtcaaacacagtggcaggtatacacaca gaaaaaaatacactggagctcagtagcagtgtgctcatcaacataaataatcaacttacc ctagacagcaacacaaagtacttccacaaattgaacatcccccagctggacttctccagc caggctgacctgcacagtgacctcaagaccctgttggaagctggacacatagcatggact tcttctggaagagcatcctggaaattggcctgccacgaattctcagatgagggaacacat gaatcccaaagcagctttactgtggaggagtccatcacttccttcagattgtctaataag atcaacagcaaacacctaagagtaaaccaaaaaatactgtatgagtctcgattcctcaac ttctctaagtttgaaatccagtcacaagctgaatgtcagcatgtgggtcgcagtgttcta actgctaaaggcctggcactgcttcaagaggggaaggcggagataactggcaaccatgat gctcatttaaatgggaaagttgttggaactttgagaaattctcttttcttttcagcacag ccatatgagatgactgcatccacaaacaatgaagggaacttgagagttagctttccatta aaactgacagggaagatagactttctgaataattatgcactgtttctgagtcctagtacc cagcaagccagttggcaagcaagtggcaggttcaatcaatataagtaccatcaaaatttc tctgctggcaacaatgagaaaagcatcgaagcccacataggaataaatggagaagccaac ctggatttcttaaacattcctttaacaatccctgaaatgactctaccttacacaaagctc acaactccccagataaaagaaatctccttatggaaaaagacaggcttgaaggatttcttg aaaacaacaaagcaatcttttgatttaagtgtaagggctcagtataagaaaaacaaagac aagcactccatcccagttcctctggatgccttctacgctcttatccatcgtaacatcaat tccttctccaggcttttcgagacagtcagaaaccaggcactagatttttttatcaaatcc tataatgaagcaaaaactacatttgataagtacaaagttgaaaaatcccttaaccagcaa cccaagatctataaaattcctggatacactattccagttgccaacattgaagtgtctccc ttcacagtgaagatgttaacatttgagtatatgatccccagagagatcagcacccccagc atcactgtcctgggttctggcatctccgtaccctcatacacgttagccctgcccttctta gagctgccggcccttcgtgtccctaaggaactttctgagctttctcttccagagttcaag gtattgagtaccataaacaaaattttaattccagccctgggcaatattacctatgatttt tcctttaaatcgagcgtcatcacactgaataccaatgttggtctgtataaccagtcagat attgtcgctcattttcttacttcatcgtcttctgtcatggatgcactgcagtacaaatta gagggcacctcaagtttgacgaggaaaagaggactaaagttagccaccgctttgtccctg agtaacagatttgtggagggcaatcatgacagtaccgttagtttcaccaagaaaaatatg gatgcatcagtgacaacaacggcaagggtccaaattccaattttgaaaatgagtttcaag caagagcttcatgggaataccaagtcaaaacctactgtctcttcagccattgaattaaag tataatttcaattcccccaaactgctctctgctgctacgggagcagttacccacaagctc accttagaaagcttcacctcttacttttccattgagtcatctaccaaaggaggtgttgag ggttcttttggttcatggggatattcagggtctcttgccagtgaagccagcacttacttg aattccaagggcaccagatcttctgtgacactgcaaggagactccaaagcagatggtctc tgggacctcaaagtaaaagaaaattttgctggagaagccacactccaacgcatatatacc atctgggaacaaaatatgaaaagccatttagagctagggggcctcattttaacatctgga gagcatacaagcaaagccaccctggagctctccctgtggaaaatatcagccctcgttcag gtccgtgcacatcagcccagttccctccttaaaatcaatttccttggccaggaagtctcc ttgaatgttaacactgagaaccagaaaatcagctggaacagtgaggtccaggttcattct gggtctctccagaacaatatacagctctctaatgaccaagaagtggctcgctttgacatg gcagtctccttagaagggtacctacggttcctcaaagatactgtcctaccggtttatgac aaaagcttatgggacctcctaaagctgaatgtcaccaccagccttaataggaaacagtat ctccgtgctgcaactgccctcatatataccaaaaaccccaatggttatcttgtttctatc cccgtgcaagaattgaatgataaattcattattcctggactgaaacgaaataatcaaaat tccgttcatgtcacacctacattccaagtcccctttacagatcttcaggttccatcctac acacttgaccttagtgaaataaaaatctacaagaagctaagtactcttccattgaccttc aacgtatcaactctacccaaagtaaaattcccccgagttgatgtgttaatacaatactct aaaccagaagcctcctctgttcccttttttgagataactgtgcctgcatctcagttgact gtgtcccaattcacccttcccaaaagtatttcagttggcagcactgttctggatctaaac acagtggccagtaacatcgcagactctgagctgccgaccatcaccatgcctgagcagact cttgagattccttccatgaagttctctgtacctgctggaattctcgttccttcctttgga acactgaccgcgcgttttgaggtggcctcgcccttgtataacaccacttggagtgctggc ttgaaaaacaaaggagatcatgttgaaacattccttgattccacatgcagctcaaccatt cagttcctggaatatgacctaaatgttgtaggaacacacaaaatcgaaggtggcatgtta gtgtgtaagactaacgcatcctttgcacaccgtgacttcagtgcagaatatgaagaagat ggcaaatatcaaggacttgggtactggaatggaaaggttgaccttaacatcaccagccca acattaactgatgtccgtctgcactaccaagaaaatgagaaccacttctcctcatcagta gcctccccagccataggcactgtggtcatcgacgtgaaaaacattagcgataccgtattg ggatggaacctctactaccgcccccaggcctctccagataaaatactcaacatattcaaa actgagttgagggtcctggaattggatgatgaaattcagatcaaagctaactgggaagaa ggagctgtgtccgaattgctaagctcgctcaaagacagtgtgcccagggccacgggagcc ctttatgactatgtcaacaagtaccaccaggagtacacgggacttgatctgaaagatgct tctttaaaactgaggagaggcctacaggacagcgctgatcaggtatatcaaggggccatg aggcagattgatgaagtggacatggagctccaaaggatggccagaggcaccactgaaacc tacctgcagtggaaggacaaggcccagagtctgtaccaggaactgttggctcaggaggac cgcagtggcttccagagactccagaagaaggtgtcagacagcttaataggagttactcag agatacagcgtgacagtcaagcatgcgactgacttgctcattgatctcctgaatgtaacc agatttcagctcccaggaagagccagaaactacactgcagatgagctctgcactgtagtc atacaggaaatagcgaagcgactgtcccaggtacattcaaatatccataaaggattacat atactgttttcctatttactatacctgatggaggagtctgagttatacaaggacctaaac aataaattttcttttacatcaatgtgcaatcaactaatagatatggtcttggagtgtatg aaaacgtttctatttttctcacaagagatccaaaaggcacttagttacctccaatctacc atgatgacagagatgctaagtgatcttcagaggtctctacaagacattttccaagagata gaaagtgaacttaaacgcttcaaggagaagaaattgactgatttcattaatcaaacccta cagaatatcaatacaatctccgacatatacatttcatttgtttttagattcctgaaagaa aacctaggctataactttgttgagtttaatgaactaatccaaaacaaacttcaggtagct tctcaagaattacagcagctccttcagtacgtgcaggctcttcaccaagaatattttgat ccaactacggttggctggacagtgaaatattatgaatttgaagaaaagatcatcaacctg atcaagaacctagtagatgtccttaaggacttccattccaaatacattgttggtgctact gattttgcttcccaactctcaagtcagattgaaccattgatacagaaaagtttgcaggag tatcttagcatccttgccaacgcagagggaagggggaaagagaagattacagagctttct accagtgctcaggaagtaattaaaagctgggctgttgcagtgaaggaaatcatttctgat taccaccagcagttcacatataaactacaggagttttcagaccagctctctgattactgt gaaaaattcatctctgagtctaaaagattgattgacctgtccagtcaaaactaccacatg tttctgaactatatcatggagttgctgaaagagctacaatcagccacagtcaatgacatg agcccctacataaaggttgctccaggagagtttactatcaccttctga

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