Bubalus bubalis (water buffalo): 102401380 Help Entry 102401380         CDS       T05912                                  Symbol DNAH8 Name (RefSeq) dynein axonemal heavy chain 8   KO K10408   dynein axonemal heavy chain Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub04814   Motor proteins bbub05014   Amyotrophic lateral sclerosis bbub05016   Huntington disease bbub05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:bbub00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     102401380 (DNAH8)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     102401380 (DNAH8)    05016 Huntington disease     102401380 (DNAH8)    05022 Pathways of neurodegeneration - multiple diseases     102401380 (DNAH8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:bbub03037]     102401380 (DNAH8)    04812 Cytoskeleton proteins [BR:bbub04812]     102401380 (DNAH8) Cilium and associated proteins [BR:bbub03037]  Motile cilia and associated proteins   Dynein arm    102401380 (DNAH8) Cytoskeleton proteins [BR:bbub04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      102401380 (DNAH8) SSDB OrthologParalogGFIT Motif Pfam:  DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 DYN_lid DYH2-5-8_CC AAA_22 AAA_16 Mg_chelatase MJ0013 SUZ Motif Other DBs NCBI-GeneID:  102401380 NCBI-ProteinID:  XP_044786444 LinkDB All DBs Position 2:complement(38956101..39288177) Genome browser AA seq 4728 aa AA seqDB search MSAEEGDPPPPEEAAPPSSGESEPPGSEEVAPPDPGDEAPPPPSSEEAPTLPEEVSEGDT GSLSEKAPTSSLSDYLNLLPSDERIVMPDDDELEPGRVRPRPAPRMVQSMLSDVLSQSSR RSSKYRRSMSGIPNLQETLKERQARYRDARENRKMKIDPSYKYIFEILSEKLGLDIVTVE ELILDCPSLEAFTLFFMKDGCKTLKFLYQEGDVPGLECGRTIAGATKGAKMMRLYVDNAA PEKLKGQCVFFVRCHNDIPINTKNIQEEVLFTVLDASEGLLVGIRNMLANIFLPAILATN SWGALNQSQQGESEKHIFIETINRYLSFLDGARISIEGTVKLKKIDNVDFSKLHTFEDVT LAASNSETVRQLEDVLMIWYKQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFNYII EQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNY DLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGTNHVW DQETPVVLKKIQDCIFLFKEYQASFHKTRKQILESSGEKSFEVSEMYIFGKFEAFCKRLE KITEMITVVQTYSTLNNSTIEGIDILAIKFKNIYQGVKKKQYDILDPRRTEFDTDFLDFM TKINALEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNIPCLQLEINHTIERILQYYVAE LEATKKLYHSQKDDPPLARNMPTIAGKILWVRQLYRRISEPINYFFKNSEILSSAEGKAV IRQYNKISYVLVEFEVVYHTAWIREISQLQYALQATLFVRHPETGKLLVNFDPKILEVVR ETKCMIKMKLDVPEQAKRLLKLESKLKGDKLYLQGLLQHYDDLCQEVPPVFVNLMTPKMK KVEAVLRQGLTILTWSSLTLESFFQEVDSVLGMFNQLLKKINDLCEMHIDAVLKEIAKTL LISLPETGATKVEDMLTLNETYTKEWAEVLNHKSKHVEEAVKELISIFETIYEVKYSGKG ARHLPELRKHVVFGSEGEDVESADYDANIVPEADVKDDKEDEFKKECKEVYAFFSHQLLD SLQKATRLSLDTMKRRIFVARQVENIPYGRKRSEDVISFLKSEVHLAIPNVVMVPSLDDI QQAINRMIQLTLEVSRGVAHWGQQSRHIKRVISSTSRTTMDLAHSSPGKQLKKEERSFEE MIPARKLKNFYPGVAEHKDISKLVLLLSSSMNSLRKAVHEALQDFQKYKTLWTEDRDVKV KEFLANNPSLTEIRSEILHYATFEQEIDELKPIIVVGALELHTEPMKLALSIEAKAWKML LCRYLNEEYKKKMSDMIAFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGP IEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQDELVQVQPKFKSNLLESVE VFREDVMNFAEAYEMEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFGLPV TDYEVLHKTRKELNLLQKLYGLYDTVMGNISGYYEILWGDVDIEKINAELLEFQNRCRKL PKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCL RNIMEAPLLKNKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGT ESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLE AVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPHLHEQL EVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHA KDYDRIMAVISREGEKIILDSPVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGF QLLPFLNHFPAQVGLLGIQMLWTHDSEEALNNAKDDRKIMQVTNQKFLDILNTLISQTTH DLSKFDRVKFETLITIHVHQRDIFDDLVKMHIRSVTDFEWLKQSRFYFKEDLDQTVVSIT DVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRC LGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTAR KERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMR VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS ELSTVMRGLRDMNLSKLIDEDEPLFLSLINDLFPGLQLDSNSYVELQAAVANQVQLEGLI NHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTMVITILMKALTECGRPHREMRMNPKAI TAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLVLDGPVDAIWIENLNSVLDDN KTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKR TTQENNVFLTLYDKIFEDAYTFMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGISC VEHLHKLFVFALMWSLGALLELESRDKLEAFMRSHESKLDLPEIPKGLTQTMYEFYVTDY GDWEHWNKKLQPYYYPTDSVPEYSSILVPNVDNVRTNFLIDTIAKQHKAVLLTGEQGTAK TVMIKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRMGSTYGPPGGRKMTVFI DDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDI PQRLKRQFTVFNCTLPSNASIDKIFGVIGCGYFDSCRRFKPEICEMILNLVSASRVLWQW TKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKADECASVHVLLSLFKHECNRVIADRFIT PDDEQWFNTQLVRSVEENVSPDVGSYILPEPYFVDFLREMPEPTGDEPEDTTFEVPKVYE LVPSFEFLSEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVG GSGKQSLSRLASFIAGYQIFQITLTRSYNVSNLTDDLKGLYKVAGADGKGITFIFTDNEI KDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRS RKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALVAVASYFVSGYSIVCS SDTKKQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYTEKVKYINE QAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASVKADEVLAEVTVSAQASAKVKNE VQEVKDKAQKIVDEIDSEKVIAETKLEAARPALEEAEAALNTIKPNDIATVRKLAKPPHL IMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLWSLQQFPKDTINEET VELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMATFYGVNREVLPLKANLAKQEGRLA VANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADMCRKKMQAASTLIDGLSG EKVRWTQQSKEFRAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKEQWEIELKARKIPF TENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSK EKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTTFKV KVGDKECDVMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQ ELESERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKLTAAEVSE KLHVAAETEVKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMAR SEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQA LIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDA PEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWE ESDTRTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLIQMSTQQGGWV LLQNCHLGLEFMEELLETLTITETIDDTFRVWITTEPHVRFPITLLQTSLKFTNEPPQGV RAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADF SASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMF EPSFCFYTGYKIPVCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETIT NIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYVPHEVKARLIKMGHLNSMNIFLRQEI DRMQKVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQIWKRVSWDSSTLGFW FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVTIHNEV LRQTKEEVTSPPAEGVYIYGLYMDGAAWDRRNGKLTESTPKVLFTQLPVLHIFAINSTAP KDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDIK NT seq 14187 nt NT seq  +upstreamnt  +downstreamnt atgagcgctgaggaaggcgacccaccccctccggaagaagcagcccctccctcgtccgga gaatcggagcctcctggttcagaagaggttgcccctccagatccaggagatgaggctccg ccccctccttccagcgaggaggccccaacccttcccgaagaggtgtctgagggagataca ggctctctttccgagaaagcccctacttcctctttaagtgattatttgaatctccttcct tctgatgaaaggatagttatgccagacgatgatgagttggaaccaggcagggtgcgaccc aggcctgcgccgcgaatggtccagtcaatgctttctgatgtgctctctcagtcttcccgc agatcatccaaataccgccgaagtatgagtggcattccaaatctacaggaaacattaaaa gagagacaggcaagatatagagatgcaagagaaaaccgaaaaatgaaaattgacccttcc tacaagtatatatttgaaattctgtcagaaaagcttggcctggacatagtaactgttgaa gaattaattttggattgcccatctctggaagcatttactctcttttttatgaaagatggt tgtaagacactgaaatttttgtaccaagaaggagatgtacctggtcttgaatgtggtcga actatcgctggagcaaccaaaggggcaaaaatgatgagattgtatgtagacaacgcagcc ccggagaaactaaaaggacagtgtgtattttttgttcgctgtcacaacgatatccctata aatactaaaaatattcaggaagaagtgctatttactgttctggatgcatcggaaggactg ctagttggaattagaaatatgctggcaaatatatttctaccagctattcttgcaacaaat agttggggtgctttaaaccagtcccagcaaggagaatctgaaaaacacattttcattgaa accatcaacagatacctttcctttttagatggtgctagaataagtattgagggaacagtt aagctaaagaaaatagacaatgttgatttttccaaactgcatacctttgaagacgtcaca cttgcagcgagcaattcagaaaccgttcgtcagctagaggacgtgctgatgatatggtac aaacagatcgaacaggtacttattgagagtgagcagatgagaaaagaagctgatgactcg ggtccactcactgaattggaacactggaaacgcatgtcagccaaattcaattatatcatt gaacagattaaaggaccaagttgtaaggctgttataaatgtgcttaatgttgcacactcc aaactcttaaagaactggcgtgatttggatgcaagaatcacggatacggctaatgaatca aaagataatgtcagatatttgtacactctagaaaaagtatgtcaacctctctataactat gatctagtttccatggcacatgggatacaaaatttgataaatgccatcagaatgattcac agtgtgtccaggtactataatacttctgagagaatgacctcattgtttattaaggtaacc aaccaaatggtgacagcatgtaaagcatatattactgatgggggaactaatcacgtatgg gatcaggaaacaccagtggtactaaagaaaattcaggactgcatttttctattcaaggaa tatcaggcatcttttcataaaacaaggaaacagattttagagtcctcaggggaaaaatct tttgaggtttcagaaatgtacatatttggaaaatttgaagctttctgcaaaagactggag aagattacagaaatgataactgttgtgcaaacatactcaaccttaaacaattctaccata gagggaatagacattttggcaataaaattcaaaaatatatatcaaggggttaagaagaaa cagtatgacattctggatccaagaaggacagaatttgacacagatttcttagattttatg acaaaaatcaatgctttagaggtacagatacaggcatttatgaacagtagttttggaaaa attttatcttctcagcaggctcttcaactgcttcaaagattccagaaactgaacattccc tgtctgcagttagaaataaaccacaccattgagcgtattcttcagtattatgtcgctgaa cttgaagctaccaagaagctttatcattctcaaaaagatgacccccctcttgctcgcaac atgcccactatagcaggaaagatcctctgggtgaggcagctgtatcgccggataagtgag cccatcaactatttcttcaaaaactcggaaattttgtcaagcgcagaaggcaaagctgtc atccgtcagtataataaaatttcctatgttctggtggaattcgaggtggtctatcacaca gcctggatcagagagatctcccagttacagtacgctttgcaagccacactttttgtgcga catccagaaacaggaaagttgctggttaattttgaccccaaaattttggaagttgttcgg gaaactaagtgcatgataaaaatgaagctggatgtaccagaacaggcaaagagattgcta aaattggaaagtaaattgaaaggagataaattgtacctgcagggtctcctgcaacattat gatgatttatgtcaggaagtgcctcctgtgtttgtcaatctgatgacccctaaaatgaaa aaggtggaagctgtgttaagacaagggctcacaatattgacatggtcatctttaacacta gaaagcttttttcaggaagttgactcagttttgggtatgttcaaccaactcttaaagaag atcaatgacttgtgtgaaatgcatatcgatgcagttctaaaggagatagccaaaacattg ttaatttccctgcctgaaaccggtgctaccaaagtagaagatatgttgacactcaatgag acatacacaaaagaatgggctgaggttctaaaccacaaaagtaagcatgtggaagaagct gtcaaagaacttatatcaatatttgagactatttatgaagttaagtacagtgggaaagga gcaagacacttaccagagctgagaaagcacgttgtttttggaagtgagggagaagatgtt gaaagcgctgattatgatgctaatattgtgcctgaggctgatgttaaagatgataaagaa gatgaatttaagaaggaatgtaaagaggtctacgcttttttctctcatcaattactagac agtcttcaaaaagctacacggttatctttggacacaatgaaaagaagaatatttgttgcc aggcaagtggaaaatatcccttatggacgaaagcggtcagaagatgttatttctttttta aaatctgaagtacatcttgcaattcctaatgtggtaatggttcctagcttggatgacatt caacaagccattaaccgtatgatccagttaaccctggaggtcagcagaggagtagctcac tggggccagcagtcccgtcacatcaagagggtcattagcagtacctcccgcacgactatg gacttggcccattcaagcccaggaaagcaactgaagaaggaagaaagatcctttgaagaa atgattcccgcacgtaagctgaagaatttttaccctggagtggcagagcacaaggatatc tccaagctggtcctcctcctttcttcctccatgaactctctgagaaaggcagttcatgaa gccctgcaggactttcagaagtacaagacactctggacagaggaccgagatgtgaaagtg aaggagtttttggctaacaatccctctctgactgaaatcagatctgaaattctacactac gcaacttttgaacaggagatcgatgagttgaagcctattatagttgtaggagcacttgaa ttgcatacagagccaatgaaattggccttatcaattgaggctaaggcatggaagatgcta ctctgtcgatatttgaatgaagaatacaaaaagaaaatgtcagacatgatagcatttatt aatgaatacttgaaaaagttatctagacctattcgtgacttagatgatgtcagatttgcc atggaagccttgtcttgtatccgtgataatgaaattcaaatggacatgactttgggacca attgaagaagcctatgctattttaaaccgatttgaagttgaagtcaccaaagaagaatca gaagcagtagacaccttgagatattctttcaacaaattgcagagtaaagcggtttctgta caagatgaactagtacaagtacagccaaagtttaaaagtaatctacttgagtctgtggaa gtttttcgtgaggatgtgatgaactttgcagaagcgtatgaaatggaaggacccatggtt ccaaatataccaccccaagaagctagcaacaggctacagatctttcaggccaattttgat gatctatggaggaaattcgttacatattcatctggagaacaactttttgggttgcctgtg actgactatgaggttttacacaaaactagaaaggaactcaacttgctgcagaagctgtat ggactgtatgatactgtgatgggcaatattagtggttattatgagatactttggggagat gtagatattgaaaaaattaatgcagaacttctggagtttcaaaacagatgtcgtaaactg ccaaaaggacttaaagattggcaagcttttttggatctgaaaaaaagaattgatgatttc agtgagtcatgtcctctactagaaatgatgaccaataaggcaatgaaacagagacactgg gatcggatctctgagttgactggaaccccatttgatgtggagtcagattctttttgtctc agaaatattatggaagcaccgctccttaaaaataaggatgatatcgaggatatttgcata tctgccattaaggagaaggatattgaagccaagctgactcaggtgattgagaactggacc aatcagaacctgagttttgcagcctttaagggaaagggagaactcctgctcaaaggaact gaatcgggagagattatcaccttgatggaggatagtttaatggttttgggttccttacta agcaacagatataatgctccatttaaaaaaaatattcagaattgggtgtataaattgtct acttcctcagatataattgaagagtggctagtagtccagaacctttgggtttatcttgag gctgtctttgtaggtggtgacatagccaaacagctaccacaggaagcaaaacgttttcag aatattgacaagtcatggataaagataatgcagcgagctcacgagaatcccaatgtgatt agttgctgtgttggagatgaaaccatggggcagcttttacctcatttacacgaacaatta gaagtatgtcagaagtcacttacagggtatttggagaagaagcgattactatttccaaga ttcttctttgtgtctgatccagttctcctggaaattcttggacaagccagtgattcccat accatccagccacatctccctgcagtgtctgacaacataaatgaggtgacctttcatgca aaagactacgatcgtatcatggctgtcatatcaagagaaggagaaaaaatcattttggat agtcctgttatggccaaaggtcccgtggagatttggcttctggacctattaaaaatgcag atgtcgtcactgcataatataattcgatccgcattctatcaaatcagtgattcaggattt caactgttacctttcctcaatcactttccggcacaggttgggcttctgggaattcagatg ttgtggacacatgattcagaagaggctttaaataatgcaaaagatgacaggaaaattatg caagtgacaaaccagaaatttttggatattctaaatactctcattagtcagacaacacat gacctgagcaagtttgacagagtgaaatttgaaactctaattaccatccatgtgcatcag agagatatttttgatgacttggtaaaaatgcatatcagatctgttactgattttgaatgg ctcaaacagagtagattttactttaaggaagatttggatcaaacagtggtgtctattaca gatgttgactttatttaccagaatgaatttctgggatgcactgatcgtcttgttatcacc ccgttaacagatcggtgctacatcactttggcacaggctttgggaatgaacatgggaggg gctccagcaggacctgcaggcactggcaaaaccgaaactacgaaagacatgggaagatgt ctggggaaatacgtggtcgtgtttaattgctcagatcaaatggatttcagagggctagga aggatttttaaaggtcttgcacagtcaggttcctgggggtgttttgatgagtttaacaga attgaattgcctgtgttatcagtggcagcccaacaaatttacatcgtcttgacagcaaga aaagagagaaaaaaacagtttattttttctgatggtgattgtgttgatctaaatccagaa tttggaatcttcttaacaatgaaccctgggtatgctgggcgccaggaactaccagagaac ttgaaaattcagttcagaactgttgctatgatggttcctgatagacagatcattatgcga gttaaacttgcaagctgtggttttcttgaaaacgttatcttggctcaaaagttttatgta ctttacaaactctgtgaagagcaacttactaagcaggttcattacgactttgggttgaga aatattctatctgtattgaggacacttggatctcaaaaaagagccagaccagaagatagt gaattaagcacggtcatgagaggactgagagatatgaacctttctaaattgattgatgaa gatgaacccctgttcctcagcttaatcaatgacctgtttccaggattacaactagatagt aatagttacgtggaactgcaagctgcagtcgccaaccaggttcagctggaaggtttgatt aaccatccaccctggaatctcaaactcgtgcagttgtatgagacgtctctggtccgtcat ggtttgatgactcttgggcccagcgggtctgggaagacaatggtcataacaatcctgatg aaggcactgacagagtgtggaaggcctcacagggagatgagaatgaatcccaaagctatt accgctcctcagatgtttggccgactggacacagcgaccaatgactggacagacgggatt ttttctactctgtggagaaaaacattaaaagctaaaaaaggtgaaaacattttcctcgtt ttagatggccctgtggatgccatttggattgagaacttaaattccgtgttggatgacaat aaaaccctcacactggccaacggagatcgcatccccatggccccaagctgcaagcttttg tttgaagtccacaatatcgagaacgcctctccagccacggtttctaggatgggcatggtg tacatcagcagctctgccctcagctggagaccaatactgcaggcatggttgaagaagcgt actactcaggaaaataatgtattcctaactctgtatgataaaatatttgaggatgcatat acatttatgaaactgaacctcaatccgaaaatgcagctcttagagtgcaactatattgtg caatctctcaatcttctggaaggcttaatcccctccaaagaagaaggtggcatttcgtgt gtcgaacatcttcataaattatttgtgtttgctctaatgtggagtttaggagcccttctg gaattagaaagcagagacaagcttgaagcttttatgcgaagtcatgaaagcaagctagat ttaccagaaatacctaaaggcttgactcaaaccatgtatgagttttatgttactgattat ggtgattgggagcattggaataagaagcttcagccgtattattatccaactgacagtgtt ccagaatattcatcaattttggttccaaatgttgacaatgttagaacaaattttttgata gacaccattgcaaaacagcataaagctgttttactcacaggggagcagggaactgcaaaa actgtaatgattaaggcctatttgaaaaaatatgacccagaagtacagttatctaaaagt ctaaacttttcatctgccacagagccaatgatgtttcagagaacaattgaaagctatgtg gacaagcggatgggaagcacatatgggccacctggaggcagaaagatgactgtatttatt gatgacattaatatgcccgtgattaatgaatggggagatcagataactaacgagattgtg cgacagatgatggagatggaaggaatgtacagcttggataagcctggagacttcaccact attgttgatgtacagctcatagcagcaatgatccatcctggaggcggtcgaaacgatatt ccgcaacgtttaaaaagacaatttactgtgtttaattgcacattgccttcaaacgcttca atagacaaaatctttggagttattggctgtgggtattttgattcttgcagaaggttcaaa cctgaaatatgtgagatgattttgaatttggtttcagcgagcagagtgctgtggcagtgg actaaggtgaagatgctgcctactccttctaaatttcattacattttcaatctgcgagat ctttccagaatttggcaaggaatgttaaccataaaagctgacgagtgtgcttcagttcat gttcttctgtcacttttcaaacatgagtgcaacagagtaattgctgacagatttataacg cctgatgatgagcagtggtttaatacacaacttgttcgttcagttgaagaaaatgttagc ccagatgtggggtcatatattcttcctgagccatactttgtagattttctccgtgagatg cctgagccaactggagatgaacctgaagacaccacatttgaagtgcccaaagtctatgag ctggtaccatcctttgaatttctgtctgaaaaactccagttttaccagagacagttcaat gagatcattagaggaacatctcttgatctggtgttttttaaagatgcaatgactcatctt attaagatttcacgaataatccgaacatcatgtggaaatgcgttgcttgtgggtgttggt ggttcaggaaaacaaagtctttcaagattggcctcttttatagctggatatcaaatattc cagataacattaaccaggtcttataatgtgagtaatctcacagatgatttaaaaggcttg tacaaagttgctggtgctgatggcaaaggcatcacttttatctttactgacaacgaaata aaagatgaggcatttctagaatatctcaacaacctgctatcttcaggggagatctccaat ttgtttgcacgggacgagatggatgaaatcacccaagggctgatatcggtcatgaaaagg gagctccctcgccatcctcccaccttcgataatctgtatgagtacttcatctcacgatca aggaagaacttgcacgttgttctctgcttttctccagttggtgagaagttccgtgcccgc tctttgaaatttccgggcttgatatcgggctgcaccatggactggttcagtcgctggcct agggaggcgctggtcgccgtggcctcctatttcgtttcaggctatagtattgtctgctct agtgacaccaaaaaacaagttgtagaaacaatgggcctctttcacgacatggtttcagag agctgtgaaagttatttccaaagataccgccgaagagcacatgtgactcccaaatcttac ctctcatttataaatggttataaaaacatttacactgaaaaggtgaaatacattaatgag caagctgaacgtatgaatattggtcttgacaagctgatggaggcaagtgaatctgtggca aaactctctcaggatcttgcagtaaaggagaaggagttggcagtggcttccgtaaaagca gatgaagtattagcagaagtcacagtaagtgctcaggcttcagccaaagtgaaaaatgaa gtgcaggaagtaaaagacaaagcccaaaaaatagtggatgaaatcgatagtgaaaaagta atagctgagaccaagctcgaggcagctagacctgcactggaagaggcagaagcagccctg aatactatcaagccaaatgatattgccacagtcaggaaacttgcaaagccccctcatctt attatgagaatcatggactgtgttctgttactatttcaaaagaaaattgaccctgtcact atggatccagaaaaaccttgctgcaagccatcatggggcgagtcattaaaattaatgagt gcaacaggattcctgtggagccttcagcagttccccaaggacacaataaatgaagagact gttgagttactacagccatattttaacatggatgattacacttttgaaagtgccaaaaaa gtctgtgggaatgtggctggtctgctgtcttggacacttgctatggcaacattttatggt gtcaacagagaagtgttgcctctgaaggctaacctggccaagcaggagggccgcttagca gttgccaatgctgaactgggcaaggcccaggcactgctggatgagaaacaagctgagctg gataaagtgcaagccaaatttgatgcagcaatgaatgaaaaaatggatttgcttaatgat gctgacatgtgccggaaaaagatgcaggcagcttccaccctcattgatggactgagtgga gaaaaagtccgatggactcagcaaagcaaagagttcagagctcagattaataggcttgta ggggatattctgctgtgcactggattcctgtcctaccttggtcctttcaatcagatattt aggaactatttgctgaaagagcaatgggagatagagttgaaagcacggaagattcctttc actgaaaacctgaatcttatttcaatgttggtagatcctccaacaattggtgagtggggg ctgcaaggcttaccaggagatgacctctcaattcagaatggcatcattgtgacaaaggcc accagatacccactcctcatagacccacaaactcaaggcaaaacatggattaaatcaaag gaaaaagaaaacgacttgcaagtaacctctctgaaccataaatatttccgcacacacctg gaggacagtctttccttgggccgaccccttcttattgaggacatccgtgaagagctggat ccagccctggataatgtattagaaaagaatttcatcaagtcaggcaccactttcaaggtg aaagtcggcgataaggaatgtgatgtcatggatacatttaaactttatattacgacaaag ttaccaaaccctgcctttacccctgagatcaacgctaaaacgtcagtcattgattttacc gttaccatgaaagggcttgagaaccagttactaaggagggtaattctaacagagaaacag gagttagagtctgagagggttaaacttttggaggatgtgacttttaataagcggaagatg aaagaacttgaagataacctcctctacaaattaagtgctacaaaaggttccttggtagac gatgaatctctcattggtgtcctccgcaccaccaagctgacagccgctgaagtcagtgaa aaactacacgtagctgcagaaacggaggtcaagattaacactgcccaggaggagttccgg cctgcggccacccgtggcagcatcctctacttcctcatcacggagatgagcatggtcaac atcatgtaccagacctcgctggcccagttcttgaaattatttgaccagtccatggccagg tctgagaagtctccactgcctcaaaagagaattacaaatattattgaatatctgacctat gaagtttttacatattctgtcagaggcttgtacgagaaccacaagttcctctttgtactc ctcatgaccttaaagatcgatcttcagagaggaactgtgaagcacagagagtttcaggct ctcattaaagggggagcagctctggatctgaaagcctgccctcccaagccatttcgctgg atcctcgatatgacctggctgaatcttgtggaactgagtaaacttccacagtttgcagaa attatgaaccagatctctcgtaatgagaaaggctggaaaagttggtttgataaagatgct ccagaggaggaaatcatccctgatggatataatgactcactggatacctgccgcaaactt ttacttatcaggtcttggtgcccagaccgtactgtttttcaagcaagaaagtatattgca gattctttggaggaaaagtacacggaaccagttatcttaaatctggagaaaacttgggaa gaaagtgatacgagaacacctctgatatgttttctgtccatgggatccgatcccacaatt caaattgacgcactggccaagaaactgaagctggaatgcagaactatctcaatggggcaa ggacaagaagtacatgctcgaaagctgattcagatgtcaacgcagcagggtggctgggtg ttactgcagaattgtcaccttggcctagaattcatggaagaattgctggagactttgacc atcacagaaaccatcgatgatactttccgagtgtggataaccaccgagccgcacgtccgg tttcccattacgttgcttcagacttctctcaaattcactaatgagccaccccaaggcgtt cgcgcaggtctgaaaagaacatttgcggggattaatcaagacctcctggacatcagtaat ttacccatgtggaagccgatgctgtacaccgtggcgttcctgcactccaccgtgcaggag cgacgcaaatttggtcccttgggatggaatattccttatgagttcaattctgccgacttt tcagccagcgttcagtttattcagaatcaccttgatgaatgtgacattaagaaaggtgtg tcgtggaataccgttcggtacatgattggagaggtgcagtatgggggcagagtcaccgac gactttgataaacgtctacttaactgctttgctagagtctggttcagtgagaagatgttt gaaccgtcgttctgtttttatacagggtataaaatccctgtgtgcaaaaccttggatcag tatttcgaatacatccagtcgttgccatctctagataaccccgaagtctttgggcttcac ccaaatgccgatatcacttaccagagtaacaccgcttctgctgtgcttgaaacaattacc aacattcagcccaaagagagtggaggcggcgtgggagagacccgggaagccattgtttac aggttatctgaagacatgctgagcaagctgcctcctgattacgttccccatgaggtgaaa gctcgtttgataaagatggggcatcttaattcaatgaacatatttctcagacaagaaatt gacagaatgcaaaaagtcatttcaatacttcgcagtagcctgagtgatctaaaattggcc attgaaggcacgatcattatgagtgagaacttgagagatgctctggacaacatgtatgat gcccgtataccccaaatctggaaaagagtgtcctgggactcctccacactgggcttctgg tttacggaacttttggaaagaaatgctcagttttctacctggatatttgaagggaggccc aatgtgttctggatgactggtttcttcaatccccaaggcttcctgaccgcaatgaggcaa gaagtgacccgtgcccacaaaggctgggccctggactctgtgaccatccacaacgaagtt ctgcggcagaccaaggaggaggtcacatcaccccctgcggaaggtgtatacatttatggg ctgtacatggatggagcagcctgggacagacggaatgggaagctcacggaatccaccccc aaggtgctcttcacacagctgcctgtgttgcacatctttgccatcaattccacggcgccc aaggaccccaagttgtacgtgtgtccgatttacaagaagcccaggcggactgacttgacc ttcatcactgtggtgtatttgcgaacagtcctctcccccgatcactggatcctgagaggc gtggcccttctgtgtgacatcaagtaa

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