Bubalus bubalis (water buffalo): 102404458
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Entry
102404458 CDS
T05912
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
KO
K14613
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01523
Antifolate resistance
bbub04977
Vitamin digestion and absorption
bbub04978
Mineral absorption
bbub04981
Folate transport and metabolism
bbub05215
Prostate cancer
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
102404458 (SLC46A1)
04981 Folate transport and metabolism
102404458 (SLC46A1)
04978 Mineral absorption
102404458 (SLC46A1)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
102404458 (SLC46A1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102404458 (SLC46A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
bbub02000
]
102404458 (SLC46A1)
Transporters [BR:
bbub02000
]
Solute carrier family (SLC)
SLC46: Folate transporter
102404458 (SLC46A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:
2.A.1.50
]
102404458 (SLC46A1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
102404458
NCBI-ProteinID:
XP_006042261
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Position
3:43225315..43232983
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AA seq
459 aa
AA seq
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MEGRANSPGEPRAWPTRSVLCRGCVEPLVFLANFALVLQGPVTTQYLWHRFSADLGYNGT
RHRDSCSNHSVDPIAQEVETLTSHWTLYMNVGGFLVGLFSSTLLGAWSDCVGRRPLLVLA
SLGLLLQTVLSIFVVQLHLHIGYLVLGRILCALLGDFSGLLAAGFASVADVSSSRTRTIR
MALLEACIGVAGMLASFIGGFLLQEQVYVNPFWLALAVLTVMTLYAAFCFGETVKERTPT
RLFTLRHHRSIIQLYVTQAPEKSRKHLALYSLAIFVMITVHLGAQDILTLYELSAPLCWD
SRLISYGSAAQQLPYLTSLLGLRLLQYCLADTWVAEIGLVFNILGMMVFAFATITPLMFT
GYGLLFLSLVVTPIIRAKLSRLVRQSEQGALFSALACVNGLAMLMASGIFNSLYPATLNL
MKGFPFLLGAGLLFIPAILMGILERDNHCPEFQEFSQSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcgcgcgaactccccgggcgagccccgcgcctggcctacccggtccgtgctg
tgccgcggctgcgtggagccactcgtcttcctcgccaacttcgccttggtcctgcagggc
ccggtcaccacgcagtacctgtggcaccgtttcagtgcagaccttggctacaatggcacc
cgtcacagggacagctgcagcaaccacagcgtggaccccatcgcacaggaagtggagaca
cttacctcccactggaccctctacatgaacgtgggcggtttcctggtggggctcttctcg
tccaccctgctgggcgcctggagtgactgtgtgggccgccgcccgctgctggtgctggcc
tccctcggcctgctgctccagaccgtgctgtccatcttcgtggttcagctgcatctccac
atcggctacttggtactgggccgcatcctttgtgccctcctcggcgatttcagtgggcta
ctggccgccggctttgcctccgtggctgatgtcagctccagccgcacgcgtactatccga
atggccctgttggaagcatgcattggggtggcgggaatgctggcgagcttcattggtggc
ttcttgctccaggagcaggtttatgtcaaccccttctggctcgccttggccgtgctgacc
gtcatgactctctatgcagcattctgctttggtgagacagtgaaggagcggacacctacc
cgtctcttcacactccgtcaccaccgatccatcatccagctctatgtgacccaggccccg
gagaagtccaggaagcacttagccctgtactcattggccatcttcgtgatgatcactgtg
caccttggggcccaggacatcctgaccctctatgagctgagtgcacccctctgctgggac
tctcggctgatcagctacggttctgcagctcagcagctcccatacctcaccagcctgctg
ggcctgcggcttctgcagtactgcctggctgacacctgggtggctgagattggcctggtc
ttcaatatcctggggatgatggtcttcgcatttgctaccatcacacccctcatgttcaca
gggtacgggctccttttcctgtcattggtcgtcacccctatcatccgggccaagctatct
agactggtgaggcaatcggagcagggcgctctcttttctgctctggcctgtgtgaatggc
ttggccatgctgatggcctccggcatcttcaactcgctctacccagccaccctgaacctc
atgaagggcttccctttcctcctgggagctggattgctattcatcccagccatcctgatg
gggatactggaaagggataatcattgccctgaattccaggagttttcccagagcccctga
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