Bubalus bubalis (water buffalo): 102404509
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Entry
102404509 CDS
T05912
Symbol
PKD1
Name
(RefSeq) polycystin-1 isoform X1
KO
K04985
polycystin 1
Organism
bbub
Bubalus bubalis (water buffalo)
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
bbub03037
]
102404509 (PKD1)
04812 Cytoskeleton proteins [BR:
bbub04812
]
102404509 (PKD1)
04040 Ion channels [BR:
bbub04040
]
102404509 (PKD1)
04091 Lectins [BR:
bbub04091
]
102404509 (PKD1)
Cilium and associated proteins [BR:
bbub03037
]
Primary cilia and associated proteins
Other primary cilia associated proteins
102404509 (PKD1)
Cytoskeleton proteins [BR:
bbub04812
]
Eukaryotic cytoskeleton proteins
Intermediate filaments
Intermediate filament-binding proteins
102404509 (PKD1)
Ion channels [BR:
bbub04040
]
Voltage-gated cation channels
Transient receptor potential channel (TRP)
102404509 (PKD1)
Lectins [BR:
bbub04091
]
C-Type lectins
Others
102404509 (PKD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PKD
REJ
PKD_4
Polycystin_dom
PKD_channel
PLAT
LRR_8
Lectin_C
WSC
Y_Y_Y
K319L-like_PKD
LRR_4
Motif
Other DBs
NCBI-GeneID:
102404509
NCBI-ProteinID:
XP_044792121
LinkDB
All DBs
Position
24:40528416..40567669
Genome browser
AA seq
4303 aa
AA seq
DB search
MPPAAPARLALALGLGLWLGALAGVPGRGCGPCAPPCLCGPAPGAACLVNCSGQGLRTLG
PALRIPADATALDVSHNLLQALDIGLLANLSALTELDISNNKISTLEEGIFANLFNLSEI
NLGGNPLECDCGLAWLPRWVEGQRVRVVRPEAATCAGPGPLAGQPLLGGALLDGACGEEY
VACVPDDSSGAVALVAFSAAPEGPLAPEACSALCFAAGQALAALSEQGRCLCGAARPPNA
SSACLPSCSGPSLPPAPACRGPSLLQHVFPASPGAALLGPQGPLASGQPAVFHVTASLPV
SSTHWDFGDGSPEVDVAGPDATHRYVLPGRYPVTALLALGVGSARLGVEVQVEAAPAALE
LVCVASVHSDETLQLGVRNRGGSGLEAAYSIVALGEEPAQVVHPLCPSDTEIFPGNGHCY
SLRAEKASWAQAQEQCRAWAGAALAMVDSPAVQHFLVSRVTRSLDVWIGFSAVEGAVAGP
APQGGAFSLESCQNWLPGEPHPATAERCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWD
AENFLVGAPNGDLQGTLSPLEQQEALLAPQEPVEVMAFPGLSPSREAFLTAAEFGTQELG
RPAQLRLQVYRAGRGAGAPGNSSEPQGRSLENRTELAPVCAPEGPLCPQANVCLPLDTPC
HPGACANGSTPGPGLPGVSYMLWKEFLFSVPAGPPAQYSVPFHGQDIALLPGDLVILQHD
AGPGTLLRCPPALSFPGSEAPYFSANASAWLSRLPAQLEAAPAGPACALRLLAATERLTP
LLGLGPNPGLRRPGRYEVRATVGNGVSRHNLTCIFNVLSPVAGLRAIYPAPQNGRLYVPT
SGSPLVLQVDSGANATAEARWPGGNASAPFEAACPAAVAALAPGCAQEANGSLFSMLTLP
GLREGEHEVEVVVENGAGRANLSLLVTAEEPIRGLRATPSPEARVLQGVLVRYSPVVEAG
SDVVFRWTIDDKQSLTFHNVVFNVIYQSAAVFKLSLTASNHVSSVSAHFNVTVEPMQRMR
GLRMSAVPPVLAPNATLALAAHVLVDSAVEVAFLWTFGDGEQAVGQFKPPYESFEVPDPT
VAQVLVEHNTSHTYTFPGEYSLTLLVSTAFENLTQQVPVSVRAALPALAVAVGSQVLVAG
RPIAFLPRPLPSPGGVLYTWDFGDGSPAVTQPQPEVNHTFASRGTYHVRLEVNNTVSHAV
ADVSVRVFEELRGLTVSLSPAVEQGVPTVVSAALDSGDNVTWTFDMGDGAVLTGPEATVE
HVYRRAQNCTVTVSASSPAGRLARSLPVHVFVLEVLWIDPVACIASQPHARLTAHVTGDP
AHYVFDWTFGDGSPNVSIQGDPTVTHSFTHSGTFPLALVLSSRVNRAHYFSSVCVEPELG
NVTLQPERQFVRLGDEARLVAHAWPPFPYRYTWDFGAEDGAARVGGPEATFTYRLAGSYL
VTVTAANNISAANDSALVEVQEPVEVTGIRVNSSHALELQQPYLFSAVGHGHPASYLWEL
GDGRQLQGPTATHAYSSTGCFEVRVAGWNEVSRGEARLNVTVQRRVRGLSVNASRTVVPL
NGSVSFSTVLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGAAQD
SIFVYVLQHIEGLQVVGGGCCFPTNRTLQLQAAVRDGTNISYSWAAQRDGGPPLAGSSKA
FSLTVLEAGTYHVQLRATNMLGSASANCTVDFVEPVGWLAVTASPNPAAVNTSVRLWAEL
AGGSSVTYSWSLEEGLCWETREPSTTLIFPSPGLCLVTVVAKNQLGSANASVEVVVQVPV
GGLSIQARELDGGFVVAGSTVPFWGQLAVGTDVSWHWAVPGGSRQGQHITVVLPDAGPVS
IQLNASNAVSWVMATHSLTVQEPIVGLVLWASRKVVEPGQPVHFQILLAAGSAVRFLLQV
GGGGLEVLPTPHFSRSFPRVGDYTVSVHAENRVSRAQAQVRISVLEAVGGLQVPDCCGPA
IATGAERNFSARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAF
NELGGVNRTLLVEVQDAIQHVALRGPRCFANRSAHFEAATSPSPRRVSYRWDFGDGAPVE
DTEAPWVVHSYLQPGDYPVQVNASNLVSFFVAQATVTVHVLACREPAVDVALPPQVLMRR
SQRNYLEAHVDLRDCVTYQTEYRWEVYRAASCQRPGRAARVALPGVDVSRPQLVVPRLAL
PVGHYCFVFVVSFGDTPLAQSIQANVTVAPERLVPIVEGGSSRVWSDSQDLVLDGSKSYD
PNLEDGDQTPLSFHWACVAATQSETGGCVLNFGPRGSSVVTIPRERLRAGVEYTFNLTVW
KAGRKEEVTSQTVLVRSGRVPIVSLECVSCKAQAVYAVSRSSYVYLEGRCHNCDGGPEHG
LWAARSFSNETLVLDATTTSTGSTGMRLVVRRGVLRDGEGYTFTLTVLGRSGQEQGCASI
RLAPNRPPRGGSCRLFPVEDVRALTTKLHFECTGWQDAEDAGAPLVYALQLRRCRQGHCE
EFCVYKGSLASYGAVLPPGFAPHFVVGLAVLVQDQLGATVVALNRSLTITLPDPPGDPAD
GTPDLTGWLHSLAGSTLPGLLRQADPQHVMEYSLALIAVLNEYEQTLPVLAEPDPRQELR
AQIRKNITETLVSLRVNTVDDIQQVAAALAQCTVSSRELVCRSCLKKTLHRLEDMMRILQ
EETATGAGTPTTIADSILNITGDLIHVASSDVQGPQPSELGAEPPSLLVASRAYQLSSAL
VGILTRSRVLNEEPLTLAGEEILAQGKRSDPRSLLCQGDVPGPGCHFSIPEAFSAALPNL
SDVVQLILLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIRQLASERAITVKVPNN
SDQAAQGQCVPAGSTVIQPRASVSVVVTPENSNPEAGLHLQLTFTVLDEQYLPDEPEPFL
AAYLHSEPRPNEYNCSASKKISLEALAGGDHKPYTFFIAPGSRDLGASYHLNLSSHFRWS
ALAVSVRLYTSLCQYFSEEHMAWRSEGLVPLEETSPREAVCLTRHLTAFGASLFVPASRV
EFTLPEPASGINHVVLLTCAVCLLTYAVMAVILRKLDQLDVRRVRAIPFCGKGGRFKYEI
LVKTGWGRGSGTTAHVGIMLYGADGRSGHRHLDGDGAFQRNSLDVFQIATPHSLGRLWKI
RVWHDNKGLSPAWFLQHVIVRDLQSARSTFFLVNDWLSVEMEANGGLVEKEVLAASDAAL
QRFQRLLVAELQRGFFDKHVWLSMWDRPPRSRFTRLQRATCCVLLVGLFLGANAVWYGAV
GDSAHRQGPVSSLAPLSLDTVAVGLVSSLVVYPVYLAILFLFRMSRSKVAGGPSPTPAGP
QALDVDSCLDSSMLDSSMLAFPGLSGEAFAGQMKQDLFLEDSKSLVCWPSSEGALSWPDL
LSDPSVMGSALQRLAQGRMGLTPGPEEDSLSLVSPSSPAKYFSASDENLIRQILAEGASS
LAPTQDTQGETDLLAGLCSAPGEKTQPAMLRSPGDTGLPSPGLTWEQPPPARLPRTGLVE
GLRKRLLPAWCAPLAHGLSLLLVAVAMGVSGWVGASFPPSVSVMWLLSSGSSFLASFLCW
EPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARK
VKRLHGMLRGLLVYMFFLLVTLLANYGDTSRHSHAYRLQSAIKQELDSQAFLAITRSDEF
WPWMSHVLLPYIHGNQSRPELGPPQLRQVRLQEALCPQPPGSRDPVCSAASGGFSTSDYG
VGWGSAALNSSEIWAYSAPDLLGVWSWGSCAVYDSGGYVQELGPSLEESRAQLGFLQLHN
WIDNRSRAVFVELTRYSPAVGLHAAVTLRLEFPAAGHAVAALSVRPFALRRLSAGLSLPL
LTSVSLLLFAVYFSVAEVRAWRREGRARATRAGTWARWLLVVLTAAAALVRLAQLGAADR
QWTRFLRRRPRRFTSFEQVAQLGAVARGLTASLLFLLLVKAAQQLRFVRQWSVFGKTLCR
ALPELAGAALGLVVLAAAYAQLAVLLVSSCVDSLQSAAQALLVLCPGTGVPALCPAESWR
LSPMLCTGLWALRLWGALRLGSVLMRWRYHTLRGELYRPAWEPQDYEMVELFLRRLRLWM
GFSKVKEFRHKVRFEGMEPLPSRSSRGSKASPDVPPPSGGSDASRPSTSSSQLEGLSLGL
GRPGPRELEPEPSRLHAVFEALLTQFDRLNQATEDVYQLERRLQRLHGRRSSAPPAPQPP
SPSPGLRPVLPSRLARASRGIGLSTGPSRASLRAKNKIHPSSS
NT seq
12912 nt
NT seq
+upstream
nt +downstream
nt
atgccgcccgccgcgcccgcccgcctggcgctcgccttgggcctgggcctgtggctcggg
gcgctggcgggggtccccgggcgcggctgcgggccgtgcgcgcccccctgcctctgcggc
ccggcgcccggcgccgcctgcctcgtcaactgctcaggccaggggctgcggacgctcggg
cccgcgctgcgcatccccgcggacgccaccgcgctggatgtctcccacaacctgctccag
gcgctggacattgggctactggcgaacctctcggcgttgacggagctggacataagcaac
aacaagatttctacgttagaagaaggaatatttgctaatttatttaatttaagtgaaata
aatctgggcgggaacccgcttgagtgtgactgtggtctggcctggctgccgcgctgggtg
gaggggcagcgggtccgcgtggtgcggcccgaggcggccacgtgcgccgggcctggcccc
ctggctggccagccgctgcttggcggagcgctgctggatggagcctgtggtgaggagtat
gttgcctgtgtccctgacgacagctcgggcgccgtggcactggtggccttctcggccgcc
cccgagggcccactggcccctgaggcctgcagcgccctctgctttgcggctggccaggcc
ctcgcagccctctcggagcagggccggtgcctgtgcggggcggcccggccccccaacgcc
tcttccgcctgtctgccctcctgctccggcccctccctgccccctgcccccgcctgccgg
gggcccagcctcctccagcacgtcttccctgcctccccgggggccgctctgctggggccc
caaggacccctggcctctggccagcccgcagtcttccatgtcactgcctcgctgccggtc
agctccacgcattgggactttggcgatggctccccggaagtggatgtcgcgggcccggac
gccactcaccgctatgtgctgcccggccgctaccccgtaacggccctgctggccctgggg
gtgggctctgcccggctgggggtggaggtgcaggtggaggcagcccccgctgccctggag
ctcgtctgtgtggcctcggtgcacagcgatgagaccctgcagctcggcgtccgaaaccgc
ggcggctcgggcctggaggctgcctacagcatcgtggccctgggagaggagccagcccaa
gtggtgcacccgctctgcccctcggacacggagatcttccccggcaacgggcactgctac
agcctgcgggcagagaaggcgtcctgggcgcaggcgcaggagcagtgccgggcctgggct
ggggccgccctggccatggtggacagccccgccgtgcagcacttcctggtctcccgtgtc
accaggagcctggacgtgtggatcggtttctcagctgtggagggggcggtggcgggcccc
gcgccccagggcggcgccttcagcctggagagctgccagaactggctgcccggggagccg
catcccgccacggccgagcgctgcgtgcgcctggggcccgctgggcagtgcaacacggac
ctgtgctcagcgccgcacagctacgtctgtgagctgcggcccggaggccccgtgtgggac
gcagagaacttcctcgtgggagcgcccaatggagacctacaggggactttgagccccctg
gaacagcaggaggccctcctggctccccaggagcccgttgaggtgatggcgtttcctgga
ctgagcccgagccgtgaagccttcctcaccgctgccgagttcgggacgcaggaactgggc
cggcccgcccaactgcggctgcaggtgtaccgggcggggcgcggagcaggggccccggga
aacagcagcgagccccagggtaggtccctggaaaacaggactgagctggcccctgtgtgc
gcaccagaagggcccctgtgcccccaagccaacgtctgcctgcctctggacaccccctgc
caccctggggcctgtgccaacggatccacgccagggccgggcctccctggggtctcctac
atgctgtggaaggagttcctcttctccgtgcctgcaggcccccctgcccagtactcagtc
cccttccatggccaggacatcgccctgctccccggcgatctcgtcattttgcagcacgac
gcggggccgggcaccctcctgcgctgccccccggcactcagcttcccaggctctgaggct
ccgtatttctctgccaatgcctcagcctggctctcccgcctgcctgcccagctggaggcg
gccccggctggccccgcctgcgccctgcggttgctggccgccacagagcggctcacccct
ctgctgggcctgggccccaacccggggctgcggcggccggggcgctatgaggtcagggcc
acagtgggcaacggtgtatccaggcacaacctgacctgcatcttcaacgtcctctcccca
gtggctgggcttcgggccatctacccagccccccagaacggccgcctctatgtgcccacc
agcggctcacccctggtactgcaggtggactcaggcgccaatgccactgccgaggcccgc
tggcccgggggcaatgccagcgcgccctttgaggctgcctgcccagccgctgtggcggcc
ctggcgcctggctgcgcccaggaggccaacggcagcctgttttccatgctgacgctgccc
gggctccgcgagggcgagcacgaggtggaggtggtggtggagaacggggccggccgggcc
aacctcagcctgctggtgacggcagaagagcccatccgtgggctccgtgccacgcccagc
cccgaggcccgcgtgctgcagggcgtcttggtgaggtacagtcccgtggtggaggccggc
tcggacgtggtcttccgctggaccatcgacgacaaacagtccctgaccttccacaacgtg
gtcttcaacgtcatctaccagagcgcagcagtcttcaagctctcgctgacggcctccaac
catgtgagcagcgtcagcgcgcacttcaacgtcaccgtggagccgatgcagcggatgcgg
ggcctgcgcatgtccgcagtgccgcccgtgctggcccccaacgccacgctggcgctggcc
gcccacgtgctggtggactcggccgtggaggtggccttcctgtggacttttggggacggg
gagcaggcggttggccagttcaagcctccgtacgagtccttcgaggtcccagaccccacg
gtggcccaggtgctggtggaacacaacacctcacacacctacaccttcccaggtgagtac
agcctgaccctgcttgtgtccaccgcctttgagaacctgacgcagcaggtgcctgtcagc
gtgcgtgctgccctgcccgccctggctgtggccgtgggcagccaggtcctggtggctggc
cggcccattgccttcctcccgcgcccgcttccatcgccgggcggtgtcctctacacgtgg
gacttcggggatggttccccagctgtcacccagccccagccagaggtcaaccacacattc
gcctcgaggggcacgtaccatgtccgtctggaggtcaacaacacagtaagccacgcggtg
gcggacgtcagcgtccgcgtcttcgaggagctccgcggcctgacggtgagcctgagcccc
gccgtggagcagggtgtgcccacggtggtcagcgctgccctggattccggtgacaacgtc
acatggacttttgacatgggggacggcgcggtgctcacgggccctgaggccacggtggag
catgtgtaccggcgggcgcagaactgcacggtgacggtgagcgcatccagccctgccggc
cgcctggctcgcagcctgcccgtgcacgtcttcgtcctggaggtgctgtggatcgacccg
gtggcctgcatcgcctcccagccgcacgcccggctcacggcccacgtcaccggggaccct
gcccactacgtctttgactggaccttcggggacggttcacccaatgtcagcatccagggg
gacccgaccgtgacgcacagctttacacacagcggcacgttcccgctggcgctggtgctg
tcgagccgcgtgaacagagcacactacttcagcagtgtctgcgtggagcctgagctgggc
aacgtcaccctgcagcccgagaggcagttcgtgcggcttggggacgaggcccgcctggtg
gcccacgcctggccccccttcccctaccgctacacctgggacttcggcgccgaggatggc
gccgcccgcgtcgggggccccgaggccacgttcacctaccggctcgcgggctcctacctt
gtgacagtcaccgcggccaacaacatctcggccgccaatgactcggcgctggtggaggta
caggagcccgtggaggtcacgggcatcagggtcaatagctcccatgctctggagctgcag
cagccctacctgttctccgctgtgggccatgggcaccccgccagctacctgtgggagctg
ggggacggcaggcagctgcagggccccacggccactcacgcctacagcagcacaggctgc
ttcgaagtcagggtggccggctggaacgaggtgagccggggggaggcccggctgaatgtg
acggtacagcggcgcgtgcgggggctcagcgtgaacgccagccgcacggtggtgcccctc
aatggcagcgtgagcttcagcactgtgctggaggccggcagcgacgtgcgctactcctgg
gtcctctgcgaccgctgcacacccatccccgggggccctaccatctcttacactttccgc
tctgtgggcaccttcaacatcatcgtcacagccgagaacgaggtgggcgccgcccaagat
agcatcttcgtctatgtcctgcagcacatcgaggggctgcaggtggtgggcggcggctgc
tgcttccctaccaaccgcacgctgcagctgcaggctgcagtgcgcgatggcaccaacatc
tcctacagctgggccgctcagcgcgacggtggcccccccctggccggcagcagcaaagcc
ttctcgctcaccgtgcttgaggccggcacctaccacgtccagctgagggccaccaacatg
ctaggcagcgcctcagccaactgcacggtggacttcgtggagccggtggggtggctggcc
gtcaccgcctccccgaacccagctgccgttaacacaagtgtcaggctctgggccgagctg
gccgggggcagtagcgtcacttacagctggtccctggaggaagggctgtgctgggagacc
cgggagccgtccaccaccctcatcttccccagccccggcctgtgcctggtcacagtagtg
gccaagaaccagctgggctcggccaatgccagcgtggaggtggtcgtgcaggtgcccgtc
ggcggcctcagcatccaggccagggaattggatggcggctttgtggtggccggttccaca
gtgcctttctgggggcagctggccgtggggactgacgtgagctggcactgggctgtgcca
ggtggcagcaggcagggccagcacatcactgtggtcctccccgatgctggcccggtctcg
atccagctcaatgcctccaacgcggtcagctgggtcatggccacacacagcctcacggtg
caggagcccatcgtgggcctggtgctgtgggccagcaggaaggtggtggagcctgggcag
ccagtgcactttcagatcttgttggccgctggctcggccgtccgtttcctcctgcaggtt
ggcgggggcggcctcgaggtgctgcctacgccccacttttcccgcagcttcccccgggtc
ggggactacacggtgagcgtgcacgccgagaaccgtgtaagccgggcgcaggcccaggtg
cgcatctcggtgctggaggctgtgggtgggctgcaggttcccgactgctgcgggccggcc
atcgccacgggcgccgagcggaacttcagcgcccgcgtgcagcggggctcccgcgtcgcc
tacgcctggtacttctcgctgcagaaggtgcagggggactccctggtcattctgtcgggc
cgtgacgtcacctacacccccgtggctgcggggctgctggagatccacgtgcgcgccttc
aacgagctgggcggcgtgaaccgcacgctgctggtggaggtgcaggacgccatccagcac
gtggcgctgcgtggcccccgctgcttcgccaaccgctccgcccacttcgaggcagccacc
agccccagtccccggcgcgtgtcctaccgctgggacttcggggacggggccccggtggag
gacacagaggcgccctgggtggtgcactcctacctgcagcctggggactaccccgtgcag
gtgaacgcctccaacctggtgagcttcttcgtggcacaggctacggtcaccgtccacgtg
ctggcctgcagggagcccgcggtggacgtggccctgccgccgcaggtactcatgcggcgc
tcccagcgcaactacctggaggcccacgtggacctgcgggactgcgtcacctaccagacc
gagtaccgctgggaggtatatcgcgccgccagctgccagcggcctgggcgcgcggcccgg
gtggccctgcccggtgtggacgtgagccggccccagctggtggtgccacggcttgcactg
cccgtgggccactactgctttgtgttcgtggtgtcgtttggggacaccccgctggcccag
agcatccaggccaacgtgacggtggcccccgagcgtctagtgcccatcgtggagggcggc
tcctcccgcgtgtggtcagactctcaggacctggtgctggacgggagcaagtcctacgac
cccaacctggaggatggcgaccagacgcccctcagcttccactgggcctgcgtggccgca
acgcagagcgagactggcgggtgtgtgctgaactttgggccccgcgggagcagcgtggtc
accatccctcgggagcgcctgcgtgccggcgtggagtacacattcaacctgaccgtgtgg
aaggccggtcgcaaggaggaggtcaccagccaaacggtgctggtccgcagcggccgggtg
cccattgtgtccctggagtgcgtgtcctgcaaggcgcaggcggtgtacgcggtgagccgc
agctcctacgtgtacctggagggccgctgtcacaactgcgacgggggcccggagcatggg
ctgtgggccgcgcgcagcttcagcaacgagacgctggtgctggacgcgacgaccacatcc
acgggcagcacgggcatgcggctggtggtgcggcggggcgtgctgcgcgacggcgagggc
tacaccttcacgctgaccgtgctgggccgctcgggccaggagcagggctgtgcctccatc
cgcctggcgcccaaccgcccgccgcgaggcggctcctgccgcctcttcccagtggaggac
gtgcgtgcactcaccaccaagctgcacttcgagtgcacgggctggcaggacgcggaggat
gcgggggcgccgctggtgtacgccctgcagctgcggcgctgccgccagggccactgcgag
gagttctgcgtctacaagggcagcctcgcctcctatggggccgtgctgccgcccggcttc
gcgccccacttcgtggtgggcctggctgtgctggtgcaggaccagctgggggccaccgtg
gtcgccctcaacaggtctctgaccatcaccctgccagacccccccggggaccctgctgat
ggcaccccggacctcacgggctggctgcatagcctggcggggagtacgctgccggggctg
ctgcggcaggccgacccccagcacgtcatggagtactcactggcgctcatcgccgtgctc
aacgagtacgagcagaccctgcccgtgctggcggagccggaccccaggcaggagctgcgc
gcccagatacgcaagaacatcacggagacgctggtgtccttgcgggtcaacacggtggac
gacatccagcaggtggcagccgccctggctcagtgcacggtgtccagccgggagctcgtg
tgccgctcgtgcctgaagaagacgctgcacaggctggaagacatgatgcgcatcctgcag
gaggagaccgccacaggcgcggggacacccaccaccatcgcagacagcatcctcaacatc
acaggcgacctcatccacgtggccagctcggacgtgcagggcccacagccctcggagctg
ggggcggagcccccctccctgctggtggcgtccagggcctaccagctctcgtctgccctc
gtgggcattctcacacgctcccgcgtgctcaacgaggagcccctgacactggcgggcgag
gagatcctggcgcagggcaagcgctcggacccacggagcctgctgtgccagggtgacgtc
ccaggccccggctgccacttctccatccccgaggccttcagcgcagccctgcccaacctc
agcgacgtggtgcagctcatcctgctcgtggactccaaccccttccccttcggctacatc
agcaactacaccgtctccaccaaggtggcctccatggccttccagacgcaggctggcgcc
cagatccctatcaggcagctggcctcggagcgcgccatcactgtgaaggtgcccaacaac
tcggaccaggccgcccagggccagtgcgtccctgccggctccaccgtcatccagccccgg
gcctcggtcagcgttgtggtcacccctgagaacagcaaccccgaggcggggctgcacctg
cagctcaccttcacggtgctggacgaacagtacctgccggacgagcccgagcccttcctg
gctgcctacctgcactcagagccccggcctaacgagtacaactgctcagccagcaagaag
atcagcctggaggccctggcgggtggcgaccacaagccctacaccttcttcatcgccccg
gggtcccgagacttgggcgcgagctaccacctcaacctgagcagccacttccgctggtcg
gcgctggcggtgtccgtgcgcctgtacacgtcgctctgccagtacttcagcgaggagcac
atggcatggcgctcggaagggctggtgcccctggaggagacctcgccccgcgaggccgtc
tgcctcacccgccacctcaccgccttcggcgccagcctcttcgtgcctgccagccgcgtc
gagttcaccttacccgagccggcctccggcatcaaccacgtcgtcctgctgacctgcgcc
gtgtgcctgctgacctacgcagtcatggccgtgatcctgcgtaagctggaccagctggac
gtccgccgggtccgcgccatcccgttctgcgggaaggggggccgcttcaagtacgagatc
ctggtcaagaccggctggggccggggctcagggaccacggctcacgtgggcatcatgctg
tatggggcagatggccgcagcggccaccgacacctggatggggatggagccttccagcgc
aacagcctggacgtcttccagattgccaccccgcacagcctgggccgcctgtggaagatc
cgtgtgtggcacgacaacaaggggctgagccccgcctggttcctgcagcacgtcatcgtc
cgggacctgcagagcgcccgcagcaccttcttcctggtcaatgactggctgtcggtggag
atggaggccaacgggggcctggtggagaaggaggtgctggctgcaagtgacgcggcgctg
cagcggttccagcgcctcctggtggccgagctgcagcgcggcttcttcgacaagcacgtc
tggctctccatgtgggaccggccacctcggagccgcttcacgcgcttgcagcgtgccacg
tgctgcgtcctcctcgtcggcctcttcctgggtgctaatgctgtgtggtacggggctgtg
ggggacagcgcccacaggcagggccccgtgtccagcctggccccgctgagcctggacacc
gtcgctgttggcctggtgtccagcctggtcgtctacccagtctacctggccatcctgttc
ctcttccgcatgtcccggagcaaggtggcagggggcccgagccccacccccgcaggcccg
caggcactggatgtggacagctgcctggactcgtccatgctggacagctccatgctcgcc
ttcccgggactcagtggcgaggcgtttgctggacaaatgaaacaggacttatttctggag
gattctaaaagcctggtgtgctggccatccagcgaaggcgccctcagctggccagacttg
ctgagtgacccgtctgtcatgggcagcgccctgcagcggctggctcagggccggatgggc
ctcacgccaggcccagaggaggacagtctctccctggtcagcccttcctcgcctgccaag
tacttctccgcttcagatgagaacctgatccggcagatcctggctgaaggggccagcagc
ctggcccccacccaggacacgcagggagaaacggacctgctcgctggcctgtgcagcgcc
cctggcgagaagacccagcctgcgatgctgcggagcccgggggacacagggctgcccagc
ccaggcctgacgtgggaacagcccccgccagccaggctccccaggacagggctggtggag
ggtctgcggaagcggctgctgccagcctggtgtgcgcccctggcccacggactcagcctg
ctcctggtggccgtggccatgggcgtgtcggggtgggtcggcgccagcttcccccccagc
gtgtctgtcatgtggctcctctcaagcggctccagcttcctggcctcgttcctctgctgg
gagccgctcaaggtcctgctggaggcgttgtacttctccctggtggccaagcggctgcac
cccgatgaagatgacaccctagtggagagcccggccgtgacacccgtgagcgagcgtgtg
ccccgcgtgcggccgccccacggctttgcactcttcctggcgaaggaggaagcccggaag
gtcaagaggctgcacgggatgctgcggggcctcctggtttacatgttcttcctgctggtg
acactgctggccaactacggggacacctcgcgccacagccatgcctaccgcctgcagagc
gccatcaagcaggagctggacagccaggccttcctggccatcacccggtctgacgagttc
tggccatggatgtcccacgttctgctcccctacatccacgggaaccagtccaggccggag
ctggggcccccacagctgcggcaggtgcggctgcaggaagcgctctgcccgcaaccgcct
ggctccagggaccccgtgtgctcagctgcctcgggtggcttcagcaccagcgactatggt
gttggctgggggagtgctgcgctcaacagctccgagatctgggcctactcagcgccagac
ctgctgggcgtgtggtcctggggctcctgtgccgtgtacgacagcgggggctacgtgcag
gagctgggtcccagcctggaggagagccgtgcacagctgggcttcctgcagctgcacaac
tggatcgacaacagaagccgcgccgtgtttgtggagctgacgcgctacagcccagccgtg
gggctgcacgccgccgtcacgctgcgcctggagttcccggctgccggacacgcagtggcg
gcgcttagcgtccgcccgttcgcgctgcggcggctcagcgctggcctctcgctgccgctg
ctcacctcggtgagcctgctcctgttcgccgtgtacttttcagtggccgaggtgcgtgcc
tggcgcagggaggggcgcgcgcgagccacacgggctgggacctgggcgcggtggctgctg
gtggtgctgacggcagccgcggcgctggtgcgtttggcccagctgggcgccgccgaccgc
cagtggacccgcttcctgcgccgccgcccgcgccgcttcaccagcttcgaacaggtggcc
caactgggcgccgtggctcgcggactgaccgcctcgctgctcttcctgctcttggtcaag
gccgcccagcagctgcgctttgtgcgccagtggtcggttttcgggaagacactgtgccgg
gcgctgcccgagctcgcgggggcagccttaggcctggtggtactcgccgcagcctacgcg
cagcttgctgtcctgttggtttcctcctgtgtggactcgcttcagagcgctgcccaggcc
ctcctggtgctgtgccccgggaccggggttcctgccctgtgccctgcggagtcctggcgc
ctgtcccccatgctgtgcacggggctctgggctctgcgtctgtggggggccctgaggctg
gggtctgttctaatgcggtggcggtaccacactctgcgtggggagctgtaccgccccgcc
tgggagccgcaggactacgagatggtggagctgttcctgcgccgcctgcgcctctggatg
ggcttcagcaaggtcaaggagttccgccacaaagtccgctttgaagggatggagccgctg
ccctcccgctcatcccggggctccaaggcttctccagacgtgccaccacccagcgggggc
tccgacgcctcccgcccctccacctcctccagccagctggaggggctgagcttgggcctg
ggccggccagggcctcgagagctggagcccgagccctcccgcctccatgctgtgtttgag
gccctactcacccagtttgatcggctcaaccaggccacagaggacgtctaccagctggag
cggcggctgcagcgcctgcacggccgcaggagcagcgcgcccccggccccccagcccccc
agcccctccccaggcctgcggcccgtcctgcccagccgccttgcccgggccagtcgaggc
atcggcctgtctacaggccccagcagagcatcactgcgggccaaaaacaagatccacccc
agcagctcttag
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