Bubalus bubalis (water buffalo): 102405427
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Entry
102405427 CDS
T05912
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00190
Oxidative phosphorylation
bbub01100
Metabolic pathways
bbub04714
Thermogenesis
bbub04723
Retrograde endocannabinoid signaling
bbub04932
Non-alcoholic fatty liver disease
bbub05010
Alzheimer disease
bbub05012
Parkinson disease
bbub05014
Amyotrophic lateral sclerosis
bbub05016
Huntington disease
bbub05020
Prion disease
bbub05022
Pathways of neurodegeneration - multiple diseases
bbub05208
Chemical carcinogenesis - reactive oxygen species
bbub05415
Diabetic cardiomyopathy
Module
bbub_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
102405427 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
102405427 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
102405427 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102405427 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
102405427 (NDUFS1)
05012 Parkinson disease
102405427 (NDUFS1)
05014 Amyotrophic lateral sclerosis
102405427 (NDUFS1)
05016 Huntington disease
102405427 (NDUFS1)
05020 Prion disease
102405427 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
102405427 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102405427 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102405427 (NDUFS1)
Enzymes [BR:
bbub01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
102405427 (NDUFS1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
102405427
NCBI-ProteinID:
XP_025133862
LinkDB
All DBs
Position
2:complement(146594475..146624477)
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AA seq
727 aa
AA seq
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MLRIPVRKALVGLSKSSKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTHTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALIALKDLLNR
VDSDMLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLQEARKPMVVLGSSA
LQRNDGAAILAAVSNIAQKIRTSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQASELSKLVNQQLLADPLIPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgtaagaaaggccttagtaggcctttccaagtcttctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaactaccgtccttcaagcttgtgagaaggttggcatgcagatt
cctcgattctgttatcacgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcctgacaaattctgagaaaactaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaagtgataggagccggtttttagaggggaaacgtgctgtg
gaggacaagaacattgggccgttggtaaaaaccattatgactaggtgtatacagtgtact
cgctgtatcaggtttgcaagtgagattgcaggagtggatgatttgggaactacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtctgaactttctggc
aatatcattgacatctgccctgtaggtgccctgacttctaagccctatgcctttaccgct
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggtcagcacaagaactggagaggtaatgaggattttgccaaggatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgaaccgatggtcagaaatgaaaagggacttttaacacataccacctgggag
gatgcactctctcgtgtagctggaatgttacagagttttcaaggcaacgatgtggcagca
attgcaggtggcttggtggatgctgaagcccttatagctctcaaagatttacttaataga
gtggattctgacatgctgtgcacagaagaggtcttccccaccgcaggagctggcacagat
ctacgttccaattatcttcttaatactacaatcgctggtgtggaggaggcagatgttgtc
cttctagttggtacaaatccacgttttgaggcaccgctatttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggcccttataggcagcccagtggatctcacttac
agatatgaccatctgggagattctcccaaaattcttcaagacattgcttcgggtagccat
ccattcagccaggtcctacaggaagctagaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggtgcagcaattcttgcagctgtttccaacattgctcagaagatt
cggacaagtagtggtgttactggtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttggatcttggctataagcctggggtggaagcaattcggaagaat
cctcctaaaatgctgtttctcctgggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattgtttatcaaggacatcatggcgacgtgggagctcctatagct
gatgttattctccctggcgctgcttacacagagaagtctgctacttacgtcaataccgag
ggccgagctcagcagacaaaagtagcagtgacgcctcccggcttggcaagagaagactgg
aaaattataagagccctttctgagattgcaggtatgactcttccatatgatactctggat
caagtgagaaacagattggaagaagtctcccctaatcttgttcgatatgatgatgttgaa
ggagctaattatttccagcaagcaagtgagctttccaagctagtgaaccaacagcttctt
gctgatccacttattccacctcagctaacaataaaagacttctacatgacagattcaatt
agcagagcctcacagacaatggctaaatgtgtcaaagctgttacagagggtgcccatgca
gtagaggaaccatctatatgctga
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