Bubalus bubalis (water buffalo): 102405560
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Entry
102405560 CDS
T05912
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X8
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00310
Lysine degradation
bbub01100
Metabolic pathways
bbub05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102405560 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102405560 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bbub03036
]
102405560 (DOT1L)
Enzymes [BR:
bbub01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102405560 (DOT1L)
Chromosome and associated proteins [BR:
bbub03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102405560 (DOT1L)
HMT complexes
Dot1-containing complex
102405560 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
102405560
NCBI-ProteinID:
XP_025148889
LinkDB
All DBs
Position
9:complement(89837874..89891825)
Genome browser
AA seq
1603 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTPVDSGAEEEKAGTATVKKPSPSKARKKKLNKKGRKMVGRKRGRPKKMSAT
NPERKPKKTQSSLDLLHAQTVSRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPT
PPALHRLLESFRIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNWELRSQSLRLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALALQLRGKPEAEPSRLHLELDCARFSLPPFSSLSPELSMNGHAAGYELCSAL
GRPSPKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSSLALPDYTRLSPAKLVLRRHLS
QDHAASGKAAASELHPRAEHAKENGLPFQSPGITNGIKLSPQDPRPSSPTALQMGEKGPE
KGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPA
RESSSTLEKQVAANTHGAGGNAAGSKNLALAPTGFAYTGSVAISGALAGSPAPLAPGAEP
PALDESSSSGSLFATVGSRSSTPQHPPLLTQPRTCGSASPAPQLCSSPRLGALGPLPDSG
KGDLPCEASFSDPESEAKRRIVFTISAGASSAKQSPSSKHSPLPSGARGDGGQGHGPDSR
KRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKI
ATISLESKSPPKTLENAGGSLAGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLQA
ASALSHNSLFAFRPGLEEPSAADAKLATHSRKSFPGTLPGAGGLSPSSLPASGFALGGGL
AADLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEGGAAESGPFANKRQLDGLGPKG
EGGLPTCGPPDKASTAHSKAGKGREREPDVKNGHNLFMAAATAPPAGLLSGPGLAPAASS
AGGAAPSVQTHRPFLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAAT
RLTNSHAMGSFSSGVAGGAVGGSLPGPPEGGEAVPACPFGSTLRPPPRCFSRNAAVTVVW
AEHSGVTRISTSTARLCKGGLGRRRGAPHGTARTDEAGEQALL
NT seq
4812 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctaaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atcagatgggtctgtgaagaaatcccggatctcaagcttgctatggagaattacgtttta
attgactacgataccaaaagctttgagagtatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaagctgaacaca
cggccgtccacggggctcttgcggcacatcctgcagcaggtctacaaccactcggtgacc
gaccctgagaagctcaacaactatgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgacctgttcgtg
gacctgggcagtggggtgggccaggtcgtgctgcaggttgccgcggccaccaactgcaaa
catcactacggtgtagagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagagg
ggggacttcctctcggaggagtggagagaacggattgctaacacaagtgttgtatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcgccgctaaaa
ggctcggtgtcatggacggggaagccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcaacacaaccacgcccaccaaggtgccc
gagagcaaggcagctgtgccggcagacacccccgtggactccggtgctgaggaggagaaa
gccgggacggccactgtcaagaagccatctccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggtgggtcggaagcgtgggcgccccaagaagatgagtgccacc
aaccccgagcgcaagcccaagaagacccagagctcactggacctgctgcacgcccagacc
gtgtcacgagcggcctcccccttgccgcaggacgcgcacaggccacctcacagtcctttc
taccagctacctcccagcgtgcagcggcctacccccgagcagctgctgctggcacccacc
ccgcccgcactgcacaggctgctagagtccttcaggattcagtacctacagttcctggca
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctaggcgcagcgcagcagctgtttggccactgccaagctcagaag
gaggagatcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcagttgagggag
cagacggagcagctggagaagggcaactgggagctgaggagccagagcctgaggctgctc
aaggcacgatgtgaggagctgaagctggactggtccacgctgtcgctggagaatctgctg
aaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctggagttg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctgcagctcaag
tcctgcgtgccgcctgatgaggcactggctctgcagcttcgtgggaagccagaggctgag
cctagccggctgcacttggagctggactgtgcccgcttctccctgccgcccttcagcagc
ttgagccccgagctctccatgaatggccatgcggccggctatgagctctgcagcgcactg
ggtcggccctcgcccaagcagaacaccccccagtacctggcctccccgctagaccaggag
gtcgtgccctgcacccctagccacagcagccggccacggctggagaagctgtccagcctg
gccctgcctgactacaccaggctatcccctgccaagctggtgctgcggcgccacctgagc
caggaccacgcggccagtggcaaggcagctgccagtgagctgcacccacgagccgagcat
gccaaggagaacgggctccctttccagagccctggcatcactaatggcatcaagctgagc
ccacaagacccccgaccttcatcccccacggctctacagatgggagagaagggccccgag
aagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagcctgcctgtc
agcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatccccctggccagc
gtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctgggccaccggcc
cgagagtcttcatccacgctggagaagcaggtggctgctaacacccatggtgccgggggc
aacgctgctgggagcaagaacctcgccctggctcccacaggctttgcatacactggctca
gtggccatcagtggggccctggccggcagcccagcacccctcgcccctggagccgagccc
ccagccctggacgagtcctccagctctggaagcctctttgccaccgtggggtcccgcagc
tccaccccgcagcacccacccctgctgactcagccacgcacctgtggctcggcctcgccg
gccccccagctctgctccagcccccggcttggcgccctgggcccactccccgactctggc
aaaggggacctgccctgcgaggccagcttctcagaccctgagagcgaagccaaaaggagg
atcgtcttcaccatctcggcaggcgccagcagtgccaagcagtcaccttccagcaaacac
agccctctgccctcgggtgcccgtggggacggtggccagggccatgggccagacagccgc
aagcggggccggaggaagcgggcatcggcggggacccccagcctgagctcaagtgtgtcc
cccaagcgccgggccttgccatctgtcgctgggcttttcacgcagtcttcagggtccccc
ctgaacctcaactccatggtcagcaacatcaaccagcccctggagatcacagcaatctca
tcccctgagagctccctaaagagctcacccgtcccctaccaggacaacgaccaaccaccc
gtgctcaagaaggagaagcccctgagccagaccaatggtgcccactactccccactgacc
tcggacgaggagccaggctctgaggatgagcctggcagtgccagaattgagagaaaaatt
gcaacgatctccttagaaagcaagtctccaccaaaaaccttggaaaatgcaggtggcagc
ctagcaggaaggaaggcgccgctggccagtgagccggtcaacagcagcaagtggaagtcc
accttctcacccatctccgacctgggcctggccaaggcggccgacagcccgctgcaggct
gcctccgctctgagccacaactctctgttcgctttccggcccggcctggaggagcccagt
gcggccgatgccaagctggccacccactccaggaagagcttcccaggcaccctgccaggg
gcaggcgggctgagccccagtagccttcctgccagcggctttgccctgggtgggggccta
gcagctgacctcagtttacacagcttcagtgatggtgcttctctctcccacaaggccccc
gaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaagagggtggc
gctgcagagtctggcccctttgcaaacaagcggcagctggacggactgggcccaaaaggc
gaggggggccttcccacatgcggacccccggacaaggcctccacagcgcatagcaaggca
ggcaagggccgcgaacgcgagcccgacgtcaagaacggccacaacctgttcatggccgcc
gccactgcgccccctgcaggcctcctcagcggcccaggtcttgccccagcggcatcctcg
gcaggtggcgcagccccgtccgtgcagacccaccgccccttcctgggcgccttcgcccct
gggccacagttcgcactgggccccatgtcgctacaggccaacctgggcccatctgtgctg
cagtccctgttcagttccgtgcccgccgccggcctggttcacgtctcgaccgccgccacc
agattgaccaactcgcacgccatgggcagcttctcctctggggtggccggcggcgcagtt
ggaggttcccttccagggccccctgaggggggagaggctgtgcccgcgtgtccctttggg
tccactttgcgcccgccacctcgttgcttttcacgaaacgcagccgtgacggtcgtgtgg
gcagagcactcgggcgtaactaggatttctacctcaaccgcgagactatgcaagggtggg
ctgggccggcggcgcggggccccccatgggacggcgaggacggacgaggccggagaacag
gctctactgtga
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