Bubalus bubalis (water buffalo): 102406755
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Entry
102406755 CDS
T05912
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00260
Glycine, serine and threonine metabolism
bbub00630
Glyoxylate and dicarboxylate metabolism
bbub00670
One carbon pool by folate
bbub01100
Metabolic pathways
bbub01200
Carbon metabolism
bbub01230
Biosynthesis of amino acids
bbub01240
Biosynthesis of cofactors
bbub01523
Antifolate resistance
bbub04981
Folate transport and metabolism
Module
bbub_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102406755 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102406755 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102406755 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102406755 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102406755 (SHMT1)
Enzymes [BR:
bbub01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102406755 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
102406755
NCBI-ProteinID:
XP_044795090
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Position
3:complement(28770473..28798271)
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AA seq
484 aa
AA seq
DB search
MAAPVNKAPRDADLWSLHEKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHVSGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETRYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQK
VAHFIHRGIELTLQIQDAVGVKATLKEFMEKLAGAEEHQQAVAALRAEVESFATLFPLPG
LPGF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcagctccagtcaacaaggcacccagagatgccgatttgtggtccttgcacgagaag
atgctggcacagcccctgaaggacagcgatgtcgaggtttacaacattattaagaaggag
agtaaccggcagagggttggactggagctgatcgcctctgagaactttgccagccgggct
gttctggaggccctaggctcttgcctgaacaacaagtactctgaggggtacccaggccag
aggtactatggtgggacggagttcatcgacgagctagaggtcctctgtcagaagcgagcg
ctgcaggtctatggcctggacccccagtgctggggggttaacgtccagccttactcaggc
tccccagcaaacttcgcagtgtacacggccctggtggagccccatggccgcatcatgggc
ctggacctgccggatgggggccacctgacccatgggttcatgaccgacaagaagaagatt
tctgccacgtccatcttttttgaatctatgccctacaaggtgaatcccgataccggctac
atcaactacgaccagctggaggagaacgcccgcctcttccacccgaggctgatcattgca
gggactagctgctactcccggaacctggactacgctcggctgcgcaagatcgctgacgac
aacggggcgtacctcatggccgacatggcacatgtcagtgggctggtggcggccggtgtg
gtgccttcgcccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcgg
ggctgccgcgccggcatgatcttctacaggaagggagtgcgcagtgtggaccccaagaca
ggcaaagagactcgctacaacctggagtcgcttatcaactctgctgtgtttccaggcctg
caagggggaccccacaaccacgccattgctggggtcgcagttgctctgaagcaggccatg
actccagagttcagagcctaccagcgccaggtggtggccaactgcagggctttggctgag
gccttgatgggactgggctacagagtggtcacagggggttctgacaaccacttgatcctc
gtggacctccgctccaaaggcacagatggtggcagagcagagaaggtgctggaagcctgc
tccatcgcctgcaataagaacacctgcccaggtgataaaagcgcactacggcccagtggg
ctgcgcctggggaccccagcactgacctcccgagggctcttggaagaagatttccaaaag
gtcgcccatttcattcacagaggcatagagctgaccctgcagatccaggacgccgtaggg
gtgaaggccaccctgaaggagttcatggagaagctggcaggagccgaggagcaccagcag
gctgtggcagccctcagggcagaggtggagagcttcgccaccctattcccgctgcctggc
ctgcctggcttctag
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