KEGG   Bubalus bubalis (water buffalo): 102409559
Entry
102409559         CDS       T05912                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta isoform X1
  KO
K05425  interleukin 12B
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04060  Cytokine-cytokine receptor interaction
bbub04620  Toll-like receptor signaling pathway
bbub04622  RIG-I-like receptor signaling pathway
bbub04625  C-type lectin receptor signaling pathway
bbub04630  JAK-STAT signaling pathway
bbub04658  Th1 and Th2 cell differentiation
bbub04936  Alcoholic liver disease
bbub04940  Type I diabetes mellitus
bbub05133  Pertussis
bbub05134  Legionellosis
bbub05140  Leishmaniasis
bbub05142  Chagas disease
bbub05143  African trypanosomiasis
bbub05145  Toxoplasmosis
bbub05146  Amoebiasis
bbub05152  Tuberculosis
bbub05162  Measles
bbub05164  Influenza A
bbub05168  Herpes simplex virus 1 infection
bbub05171  Coronavirus disease - COVID-19
bbub05200  Pathways in cancer
bbub05205  Proteoglycans in cancer
bbub05321  Inflammatory bowel disease
bbub05330  Allograft rejection
bbub05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102409559 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102409559 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102409559 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    102409559 (IL12B)
   04625 C-type lectin receptor signaling pathway
    102409559 (IL12B)
   04658 Th1 and Th2 cell differentiation
    102409559 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102409559 (IL12B)
   05205 Proteoglycans in cancer
    102409559 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    102409559 (IL12B)
   05164 Influenza A
    102409559 (IL12B)
   05162 Measles
    102409559 (IL12B)
   05168 Herpes simplex virus 1 infection
    102409559 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    102409559 (IL12B)
   05134 Legionellosis
    102409559 (IL12B)
   05152 Tuberculosis
    102409559 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102409559 (IL12B)
   05145 Toxoplasmosis
    102409559 (IL12B)
   05140 Leishmaniasis
    102409559 (IL12B)
   05142 Chagas disease
    102409559 (IL12B)
   05143 African trypanosomiasis
    102409559 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    102409559 (IL12B)
   05330 Allograft rejection
    102409559 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102409559 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    102409559 (IL12B)
   04936 Alcoholic liver disease
    102409559 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbub04052]
    102409559 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:bbub00536]
    102409559 (IL12B)
Cytokines and neuropeptides [BR:bbub04052]
 Cytokines
  Interleukins
   102409559 (IL12B)
Glycosaminoglycan binding proteins [BR:bbub00536]
 Heparan sulfate / Heparin
  Cytokines
   102409559 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_5 Ig_3 Ig_4 Ig_2 fn3 I-set ig
Other DBs
NCBI-GeneID: 102409559
NCBI-ProteinID: XP_045022463
LinkDB
Position
9:39949825..39968514
AA seq 329 aa
MQMHPQQLVVSWFSLVLLASPIMAIWELEKNVYIVELDWYPDAPGETVVLTCDTPEEDGI
TWTSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEALSRSLLLLHKKEDGIWSTDILK
DQKEPKAKSFLKCEAKDYSGHFTCWWLTAISTDLKFSVKSSRGSSDPRGVTCGAASLSAE
KVSVDHREYNKYTVECQEGSTCPAAEESLLIEVVVEAVHKLKYENYTSSFFIRDIIKPDP
PKNLQLRPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKNKREKKLFMDQTSAKVT
CHKDANVRVQARDRYYSSFWSEWASVSCS
NT seq 990 nt   +upstreamnt  +downstreamnt
atgcagatgcaccctcagcagttggttgtttcctggttttccctggttttgctggcatct
cccatcatggccatatgggaactggagaaaaatgtttatattgtagaattggattggtat
cctgatgctcctggagaaacagtggtcctcacgtgtgacactcctgaagaagacggtatc
acctggacctcagaccagagcagtgaggtcttgggctctggcaaaaccttgaccatccaa
gtcaaagagtttggagatgctgggcagtacacctgtcacaaaggaggcgaggctctgagt
cgttcactcctcctgctgcacaaaaaggaagatggaatttggtccactgatattttaaag
gatcagaaagaacccaaagctaagagttttttaaaatgtgaggcaaaggattattctgga
cacttcacctgctggtggctgacagcaatcagtactgatttgaaattcagtgtcaaaagc
agcagaggctcctctgacccccgaggggtgacgtgcggagcagcgtcgctctcagcagag
aaggtcagcgtggaccacagggagtataacaagtacacagtggagtgtcaggagggcagc
acctgcccagccgccgaggagagcctgcttattgaggtcgtggtagaagctgtgcacaag
ctcaagtatgaaaactacaccagcagcttcttcatcagggacatcatcaaaccagaccca
cccaagaacctgcaactgagaccattaaagaattctcggcaggtggaggtcagctgggag
taccctgacacgtggagtaccccacattcctacttctccctgacgttttgtgttcaggtc
cagggaaagaacaagagagaaaagaaactcttcatggaccaaacctcagccaaagtcaca
tgccacaaggatgccaacgtccgcgtgcaagcccgggaccgctactacagctcattctgg
agtgaatgggcatctgtgtcctgcagttag

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