Bubalus bubalis (water buffalo): 102409670
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Entry
102409670 CDS
T05912
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00230
Purine metabolism
bbub01100
Metabolic pathways
bbub04024
cAMP signaling pathway
bbub05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102409670 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
102409670 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102409670 (PDE10A)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
102409670 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
102409670 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
102409670
NCBI-ProteinID:
XP_006067125
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All DBs
Position
10:3385079..3650525
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AA seq
1070 aa
AA seq
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MASPEEPLAPRPQAPLPAAGDEPGSGKLRPEPGRSAAGGRSAAGPGPAPEPPGRGRAERA
WSPRPPPSSAGRASPPGGPGALSARGGGGGWVAARAPFALAFSSPVRVSAPSSFYFWPPP
PQPPPFLLPSSSAFHLPARLPGREGAAAAAAAARGGGGDAGGGGGGGQEAAPLSVPPSRS
HRGGGGGRRRLFLSPALRGLLLSPRAGPRPPPPPRLPLGPAAPRAGSRGFPGAGGGCPAP
VPGPGPNPGGGGRTARRPRGAGAALASAFPLLFGSDMEDGPSNNASCFRRLTECFLSPNL
TDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNKKSEDESAPKEVSRYQDTNMQGV
VYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFIPPGIKE
GKPKLIPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIV
TAIGDLIGILELYRHWGKEAFCLSHQEVATAHLAWASVAIHQVQVCRGLAKQTELNDFLL
DVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNQELYSDLFDIGEEKEGKP
VFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVS
RGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEK
LSYHSICTAEEWQGLMHFNLPGRLCKEIELFHFDVGPFENMWPGIFVYMIHRSCGTACFE
LEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQSSHGRFTDLERKGLLIACLCHD
LDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLE
IIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPV
TRLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
FPATEPLLKACRNNLSQWEKVIRGEESALGIPDLPEAEGSPERLPVKTDD
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgaagagccacttgctccccgcccccaggcccccctgcccgcggcgggg
gacgagcccggctctggcaaactccgcccggagcccgggcgcagcgccgccggcgggagg
agcgcagccggcccgggcccggcccccgagccgcctggtcgcggccgggccgagcgcgcc
tggtccccgcgcccgcccccctcttccgctggccgcgccagccccccggggggccccggc
gccctgtctgcgcgcggcggcgggggtggctgggttgcagcgcgcgctcccttcgcgctc
gccttctcctccccggtccgcgtctccgctccatcttccttttacttctggccgccgccc
ccccaacccccgccttttcttctcccctcctcatctgcttttcacctccccgcgcgtctc
ccaggaagggagggcgcagcggcggcggcggcggcggcccgaggaggcggcggcgatgct
ggcggcggcggcggcggcggacaagaggcggctcccctgagcgtccccccaagcaggagt
caccgcggcggcggcggcgggcggcggcggctcttcctctcccccgcgctccgaggcttg
ctgctctcgccccgcgccgggccccggccgccgccgccgccccggctcccgctcggcccg
gccgccccccgcgcgggctcccgcggcttcccgggcgccggcgggggctgccccgctccg
gttcccggtcccggtcccaacccgggcggcggcggccgaacggcgcggcggccccgaggc
gccggcgccgcgctcgcctccgcgttcccgctgcttttcggctccgacatggaagatgga
ccttctaataacgcgagctgcttccgaaggctgacggagtgtttcctgagccccaatttg
acagatgaaaaagtgaaggcctatctttctctccaccctcaggttttagatgaatttgtg
tctgaaagcgttagtgcagagactgtagaaaaatggctgaagcggaaaaacaagaagtca
gaagatgaatcagctcctaaggaagtcagcaggtatcaagatacaaatatgcaaggagtt
gtgtatgaactaaatagctatatagaacaacggttggatacaggaggagacaaccagcta
ctcctctatgaactgagcagcatcatcaaaatcgccacaaaagctgacggatttgcactg
tatttccttggagagtgcaataacagcctttgtgtgtttatcccgcctggaatcaaggaa
ggaaaacctaagctcatccccgctggtcccatcgcccagggcaccaccacctctgcctac
gtggccaagtccaggaaaacgttgctggtggaagacatcctcggggatgaacggtttcca
agaggtaccgggctggaatcagggacacggatccagtctgttctttgtttgccgatcgtc
actgcgattggggacttgattggcatcctggagctctaccggcactggggcaaagaggcc
ttctgcctgagtcaccaggaggtcgcgacggcgcacctcgcctgggcttcagtggcgata
caccaggtgcaggtatgcagaggtcttgccaaacagactgaactgaatgactttctactc
gacgtatcaaaaacctattttgataacatagttgcaatagattctctacttgaacacata
atgatatatgcaaaaaacctggtgaatgccgaccgttgtgcccttttccaggtagaccat
aagaaccaggagttatattcagacctttttgatattggagaggaaaaggaaggaaagccc
gtcttcaagaagaccaaggagatcaggttttcaatcgagaaggggatcgctggccaagta
gcaaggaccggggaagttctgaacatcccagatgcctacgcagacccgcgcttcaacaga
gaggtggacttgtacacgggctacacgacccggaatatcctgtgtatgcccatcgtcagc
cgcggcagcgtcatcggcgtggtgcagatggtcaacaagctcagcggcagcgccttctcc
aagacggacgagaacaacttcaagatgtttgctgtcttctgtgctttagccttacactgt
gccaacatgtaccacaggatccggcactcggagtgcatctacagggtcacgatggagaag
ctgtcgtaccacagcatctgcaccgcggaggagtggcaaggcctcatgcacttcaacctg
cccggccgtctgtgcaaagagatcgagctgttccactttgacgttggcccctttgaaaac
atgtggcctggaattttcgtgtacatgatccaccgatcctgtgggacagcctgcttcgag
ctggaaaagttgtgtcgcttcatcatgtctgtgaagaagaactaccgccgggtcccttac
cacaactggaagcacgcggtcacggtggcccactgcatgtacgccatcctgcagagcagc
cacgggcgcttcaccgacctcgagcgcaaagggctgctcatcgcgtgtctgtgccacgac
ctggaccaccggggattcagcaacagctacctgcagaagttcgaccaccccctggccgcg
ctctactccacgtccaccatggagcaacaccacttctcccagacggtgtccatcctgcag
ttggaagggcacaacatcttctccaccctgagctccagcgaatacgagcaggtgcttgag
atcatccgcaaagccatcatcgccacggacctcgcgctgtacttcgggaaccggaagcag
ctggaagagatgtaccagaccgggtcgctgaaccttaataaccaatcacatagagaccgt
gtcatcggcttgatgatgaccgcctgtgatctttgttctgtgacaaagctgtggccagtg
acgagactgacggccaacgacatatatgcagaattctgggcggagggcgatgaaatgaag
aagctggggatacagcccattcccatgatggacagagacaagaaggacgaggtcccacaa
ggccagctggggttctacaatgccgtggccattccatgctacaccaccctcacccagatc
ttccccgccacggaaccgctcctgaaggcctgcaggaataacctgagccagtgggagaag
gtgatccggggtgaggagagcgccctggggatcccggacctgccagaggctgaggggtcc
ccagagaggctgcccgtgaagaccgatgactga
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