KEGG   Bubalus bubalis (water buffalo): 102410133
Entry
102410133         CDS       T05912                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X2
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub01521  EGFR tyrosine kinase inhibitor resistance
bbub01522  Endocrine resistance
bbub04012  ErbB signaling pathway
bbub04015  Rap1 signaling pathway
bbub04062  Chemokine signaling pathway
bbub04081  Hormone signaling
bbub04137  Mitophagy - animal
bbub04144  Endocytosis
bbub04360  Axon guidance
bbub04370  VEGF signaling pathway
bbub04510  Focal adhesion
bbub04517  IgSF CAM signaling
bbub04520  Adherens junction
bbub04530  Tight junction
bbub04540  Gap junction
bbub04611  Platelet activation
bbub04613  Neutrophil extracellular trap formation
bbub04625  C-type lectin receptor signaling pathway
bbub04727  GABAergic synapse
bbub04750  Inflammatory mediator regulation of TRP channels
bbub04810  Regulation of actin cytoskeleton
bbub04912  GnRH signaling pathway
bbub04915  Estrogen signaling pathway
bbub04917  Prolactin signaling pathway
bbub04919  Thyroid hormone signaling pathway
bbub04921  Oxytocin signaling pathway
bbub04926  Relaxin signaling pathway
bbub05100  Bacterial invasion of epithelial cells
bbub05135  Yersinia infection
bbub05152  Tuberculosis
bbub05161  Hepatitis B
bbub05163  Human cytomegalovirus infection
bbub05167  Kaposi sarcoma-associated herpesvirus infection
bbub05168  Herpes simplex virus 1 infection
bbub05203  Viral carcinogenesis
bbub05205  Proteoglycans in cancer
bbub05207  Chemical carcinogenesis - receptor activation
bbub05208  Chemical carcinogenesis - reactive oxygen species
bbub05219  Bladder cancer
bbub05417  Lipid and atherosclerosis
bbub05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102410133 (SRC)
   04015 Rap1 signaling pathway
    102410133 (SRC)
   04370 VEGF signaling pathway
    102410133 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102410133 (SRC)
   04517 IgSF CAM signaling
    102410133 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102410133 (SRC)
   04137 Mitophagy - animal
    102410133 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102410133 (SRC)
   04520 Adherens junction
    102410133 (SRC)
   04530 Tight junction
    102410133 (SRC)
   04540 Gap junction
    102410133 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102410133 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102410133 (SRC)
   04613 Neutrophil extracellular trap formation
    102410133 (SRC)
   04625 C-type lectin receptor signaling pathway
    102410133 (SRC)
   04062 Chemokine signaling pathway
    102410133 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102410133 (SRC)
   04915 Estrogen signaling pathway
    102410133 (SRC)
   04917 Prolactin signaling pathway
    102410133 (SRC)
   04921 Oxytocin signaling pathway
    102410133 (SRC)
   04926 Relaxin signaling pathway
    102410133 (SRC)
   04919 Thyroid hormone signaling pathway
    102410133 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    102410133 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102410133 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    102410133 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102410133 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    102410133 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    102410133 (SRC)
   05203 Viral carcinogenesis
    102410133 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    102410133 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102410133 (SRC)
   05168 Herpes simplex virus 1 infection
    102410133 (SRC)
   05163 Human cytomegalovirus infection
    102410133 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102410133 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102410133 (SRC)
   05152 Tuberculosis
    102410133 (SRC)
   05100 Bacterial invasion of epithelial cells
    102410133 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102410133 (SRC)
   05418 Fluid shear stress and atherosclerosis
    102410133 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102410133 (SRC)
   01522 Endocrine resistance
    102410133 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbub01001]
    102410133 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbub04131]
    102410133 (SRC)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102410133 (SRC)
Protein kinases [BR:bbub01001]
 Non-receptor tyrosine kinases
  SRC family
   102410133 (SRC)
Membrane trafficking [BR:bbub04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    102410133 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    102410133 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    102410133 (SRC)
  Macropinocytosis
   Kinases
    102410133 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 SH3_10 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 102410133
NCBI-ProteinID: XP_044783602
LinkDB
Position
14:complement(17313258..17368029)
AA seq 542 aa
MGSNKSKPKDASQRRRSLESAENTHGGGGGGGGGGGAFPSSQTPSKPASSDGHRGPNTAF
APAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIV
NNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGESLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagtct
gccgagaacacccacggaggcggtggcggtggcggcggtggtgggggtgccttcccctcc
tcacagacccccagcaagccagcctcctctgatggccaccgcggccccaacacggccttc
gcccctgcagccgctgagcccaagctgttcggaggcttcaactcctcggacacagtcacc
tccccgcagagggcggggcccctggctggcggagtgaccaccttcgtggccctctatgac
tatgagtcgcggacagagactgacctgtctttcaagaaaggggagcggcttcagattgtc
aacaacacagagggagactggtggctggcccactcgctcagcacaggacagacaggctac
atccccagcaactatgtggcaccctctgactccatccaggctgaagagtggtactttggc
aagatcaccagacgggagtcagagcggttactgctcaatgcagagaacccaagagggacc
ttcctagtgcgagaaagcgagaccacgaaaggcgcctactgcctctcggtgtctgacttc
gacaatgccaagggcctaaacgtgaagcactacaagatccgcaagctggacagcggaggc
ttctacatcacctcccgcacccagttcaacagcctgcagcagctggtggcctactactcc
aaacacgctgatggcctctgccaccgcctcaccactgtgtgccccacgtccaagccgcag
actcaaggcctggccaaagacgcctgggagatcccccgggagtcgctgcggctggaggtc
aagctgggccagggctgcttcggagaggtgtggatgggtacctggaacggcaccaccaga
gtggccatcaaaaccctgaagcctggtacaatgtctccggaggccttcctgcaggaggcc
caggttatgaagaaactgaggcatgaaaaactcgtgcagctgtacgccgtggtgtccgaa
gagcccatctacattgtcacggagtacatgagcaaggggagtttgctggactttctcaag
ggggagacaggcaagtacctgcggctgcctcagctggtggacatggctgcacagatcgcc
tcgggcatggcttatgtggaacggatgaactatgtccaccgagacctccgggctgccaac
atcctggttggagagagcctcgtgtgcaaagtggctgacttcgggctggctcgactcatt
gaagacaacgaatacacagcccggcaaggtgccaaattccccatcaagtggacggctccg
gaagctgccctctatggccggttcaccatcaaatcagacgtgtggtcctttgggatcctg
ctgacggagctcacaacaaagggacgggtgccctaccctgggatggtgaaccgggaggtg
ctggaccaggtggagcggggctaccggatgccctgcccgcctgagtgtcccgagtcattg
catgacctgatgtgccagtgctggcggaaggacccggaggaacggcctaccttcgagtac
ctgcaggccttcctggaggactatttcacgtccaccgagccccagtaccagcccggagag
aacctatag

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