Bubalus bubalis (water buffalo): 102410308 Help Entry 102410308         CDS       T05912                                  Symbol DNAH3 Name (RefSeq) dynein axonemal heavy chain 3   KO K10408   dynein axonemal heavy chain Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub04814   Motor proteins bbub05014   Amyotrophic lateral sclerosis bbub05016   Huntington disease bbub05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:bbub00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     102410308 (DNAH3)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     102410308 (DNAH3)    05016 Huntington disease     102410308 (DNAH3)    05022 Pathways of neurodegeneration - multiple diseases     102410308 (DNAH3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:bbub03037]     102410308 (DNAH3)    04812 Cytoskeleton proteins [BR:bbub04812]     102410308 (DNAH3) Cilium and associated proteins [BR:bbub03037]  Motile cilia and associated proteins   Dynein arm    102410308 (DNAH3) Cytoskeleton proteins [BR:bbub04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      102410308 (DNAH3) SSDB OrthologParalogGFIT Motif Pfam:  AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 Dynein_heavy MT Dynein_AAA_lid AAA_5 AAA_lid_1 DYN_lid AAA_22 RNA_helicase CCDC171 ARL2_Bind_BART DUF1664 Motif Other DBs NCBI-GeneID:  102410308 NCBI-ProteinID:  XP_025130344 LinkDB All DBs Position 24:23286726..23528769 Genome browser AA seq 4069 aa AA seqDB search MDNMNDTDCSSQKIPKSDSIYHMSHSQMRPELPPLPASANEEPSELYKTVMLHSFYPPLM QRTSWTLAAPFKEQHHHSGPSDSIANNYSLTARDLKLKDLLKVYQPVTINVPREKIIQGL PSANKISSEPNKKKMKFSPKDKEDFTGMKSASTSLPMKKEVVTSLTFPESRPMSPEEQIE VMLQQEREIESKETKPSESDLERYYYYLTSGIRKDMIAPEEDKVMVRISKLISNTLLTSP FLEPLMAALVEEKETDYYSSLMKSIVDYILMDPMERKRLFIQSIPRAFPQRVIRAPVPWH SVYRNAKKWNEEHLHTVNPMMLSLKQLWFSEFRDLRFVRTAELLAGKLPLQPHEYQDVIQ KHCMEARQILLNKWIPTCAQLFVSRKEQWIHFAPKSDYDSSRNIEEYFASVASFMSLQLR ELVINSLKDLLSFFMIHKDGNDFEEPYQEMEFFIPQLIMIKLEVNEPIIVFNPSFDDCWE LIRNSFLEIIKNSEGIPKVESILFPELKGYNLILETVNADEKLVSDFVDQTFEVFQKNQV GPCKYLNVYKKYDDLLDNTAEQNITEFLKENHEIEDFVMRINSIKKRRNEIASMHITVPL AMFCLDTMTLNYDLCERAQNLKDRLIQFQVDVNRDTNTSICNQYSLIADKVSEIPINTGE LVFLIEFLKKSSNVTVFKLRRQLRDAVERLEFLMDYADLSQEDIKLNSTLFLWPDQIEDI FENSRNLLLSKRDQAEMDLIKRCSEFEVKLEGYSKELEGFRKREVMTTEEMKNNVEKLNE LSKNLDQALVEFELINKEEELLEKEKSTFPLLQTVMANKAPYEQLWVTAYEFSTKSEEWM NGPLFLLNAEEIAEEIGNMWRTIYKLTKTLADMPAPRRLAENVKIKIDKFKQHIPILTIS CNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFIEKLEPIGAAASKEYSLEKN LEKMKLDWVNMTFNFVKYRDTDTSILCAVDDIQLLLDDHVIKTQTMCGSPFVKPIETECR KWEEKLVRVQEILDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFAIVDNYWKSLMSQA VKDTRVLMAADQPRMAERLQEANLLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILS ETKDPLRVQPHLKKCFEGIAKLEFTDSLEIVGMISSEKEIVPFKQKIYPAQAKGMVEKWL LQVEQMMLASMKEVIKLGIEAYVQVPRNQWVLQWPGQVVICVSSIFWTQEVSQALIEKTL PDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVTKLSEDNVCDLNDFQW ISQLRYYWDSKDVQVQMITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAP EGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIE VEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKA LFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVK SVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVILPQPDY AVFMEVLNANIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTCAYKVLAAAL GDLYEAKQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWTDGVLANAFREQASSLSDDR KWIIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPKMSLIFEPADLEQASPATVSR CGMIYMEPHQLGWKPLKDSYMDTLPSSLTEEHKELVNDMFMWLVQPCLEFTRLHCKFVVQ TSPIHLAFSMMRLYSSLLDEIREIEEEESELSEGLTSQQIFLWLQGLFLFALVWTVAGTI NADSRKKFDLFFRNLIMGMDNNNPRPKSVKLTKNNIFPERGSIYDFYFLKQASGHWYTWT EYITKEEEHISANAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSVITNNF LLRLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA KEVYGAQPPIELLRQWIDHGYWFDKKDTNKLDIVDVLLVTAMGPPGGGRNDITGRFTRHL NIISINAFEDDILTKIFSSIADWHFGKGFDVVFLRYGKMMVQATMTIYKAAVENFLPTPS KSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKFIRLWIHEVYRVFYDRLIDHEDRQVFFNM VRETTSNCFKQSVEKVLIHLSPTGKIVDDNIRSLFFGDFFKPESDQKIYDEITDLKQLTV VMEYYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSASKLS TFMNSYELYQIEITKSYSGNDWREDLKKIMLQVGVATKSTVFLFADNQIKDESFVEDINM LLNTGDVPNIFPADEKADIVEKMQMAARTEGEKIEVTPLSMYNFFIEKVKKNLHIVLAMS PIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRIQVISMCKY FQESVKKLSLDYYNTLRRHNYVTPTSYLELILTFKTLLNKKRQEVDMMRNRYLTGLQKLE FAASQVAVMQVELTALQPQLIQTSEETAKMMVKIEAETQEADAKKLLVQADEKEANAAAA IAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKAMQNPPGPVKLVMESICVMKG LRPERKPDPSGSGKMIEDYWGVSRKILGDLKFLESLKTYDKDNIPPVIMKRIRERFIDHP DFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLKEAEGKLDTQMQKLNQKRA ELKLVEDRLQALNDDFEEMNTKKKTLEGNIEICSQKLIRAEKLISGLGGEKDRWTEAARQ LGIRYTNLTGDVLLSSGTVAYLGAFTVDYRAECQKQWLAQCKDKVIPGSSDFSLSNTLGD PVKIRAWQIAGLPIDSFSIDNGIIVSNSRRWALMIDPQGQANKWIKNMEKANKLSVIKFS DANYVRTLEHALQFGTPVLLENVGEELDAFIEPILLKSTFKQQGVEYMRLGENIIEYSRD FKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNKLIVE SAKNKKQLKEIEDKILEVLSLSEGNILEDETAIKILSSSKVLSEEISEKQEIASVTETQI DETRMGYKPVAVHSATIFFCISDLAHIEPMYQYSLTWFINLYMQSLAHSKKSEELELRIE YIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKEKKQINEEIWYFLLTGGIALDNPF PNPVSEWLSEKAWAEVVRASALPKLKGLMEHLEQNGNEWKFIYDSAWPHEETFPGSWKFL HGLERMVILRCLRPDKMIPAIRGFIAEHMGSVYIEAPTFDLQGSYNDSNCCAPLIFVLSP GADPMAGLLKFADDLGMGGTKTQTISLGQGQGPIAAKMINSAIKDGTWVVLQNCHLATSW MPALEKICEEVIVPESTNMGFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSY LNDPISDPVFFQSCTKAVMWQKLLFGLCFFHAIVQERRNFGPLGWNIPYEFNESDLRISM RQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSTFYCKEIEQDHYFLA PGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFQGVLLTLPR QSGGSGKSPQEVVEDLAQDILSKLPNEFDLELVMKLYPVVYEESMNTVLRQELIRFNRLT AVVDRSLIDLGRAIKGQVLMSSELEDVFSSMLVGKVPAMWMAKSYPSLKPLGGYVADLLA RLAFFQEWIDNGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTTQETVM ESNPEDGAYIKGLFLEGARWDRKKMQIGESFPKTLYDPLPIIWLKPGKSAMFLHQNIYVC PVYKTSARRGTLSTTGHSTNYVLSIELPTDRPQKHWINRGVASLCQLDN NT seq 12210 nt NT seq  +upstreamnt  +downstreamnt atggacaacatgaatgacacggattgctcatctcagaagatccccaaaagtgactccata tatcacatgagccactcgcagatgcggccagagttgccccctctgcctgcttctgctaat gaagaaccatctgaactctataagacagtcatgttgcacagcttttatccccccttgatg caacgcacatcatggaccctggctgcacccttcaaagagcagcaccaccacagtggaccc agtgattccattgccaacaactactccttgacagctcgggacctgaagctgaaggacctg ctgaaagtctaccagcccgtcaccatcaatgtccctagggaaaagatcattcaggggctg ccatcggcaaataaaatctcatcagagcctaacaagaagaaaatgaagttctcccccaaa gacaaagaggacttcactgggatgaagtcagcctcaacctccttacctatgaagaaggag gttgtgacatctttgactttcccagaaagcagaccaatgagtccagaagaacagattgaa gtgatgttacagcaggagagggaaatagaaagtaaagaaaccaaaccatctgaatcagac ttggagagatactactactatttgaccagtggaatccgaaaagacatgattgcccctgag gaggacaaagtgatggttcggatttcaaagctgatttcaaacacactgctgacaagtccc ttcctggaacccctgatggctgcccttgtggaggagaaggaaacggactattacagcagc ctcatgaaaagcattgttgattacatcctcatggaccccatggagaggaaaagactcttc attcagagcatcccccgagcatttcctcagagagtgatccgggcccctgtgccctggcac agtgtctacaggaatgccaagaagtggaacgaagagcacctgcacacagtgaaccccatg atgctcagcctgaagcagctgtggttttcggaatttagagacctcaggtttgttcgaaca gcagaattactggcgggaaaattacctctgcagcctcatgaatatcaggatgtcattcag aaacactgcatggaagcacgccaaattcttctcaacaaatggatccccacctgtgcccag ctatttgtctcccggaaggagcagtggatccattttgctcccaagagtgactatgactcc tctcgtaacattgaagaatattttgcttccgttgcatctttcatgtccctccagctcagg gagttggtcattaactctcttaaggacctcctttccttcttcatgatacacaaggatgga aatgattttgaggagccctaccaagaaatggagttctttatacctcagctgattatgatc aagcttgaagtcaatgagccaattattgtctttaatccatcttttgatgactgctgggaa ttaatacgtaactctttcttggaaattattaagaactctgaagggattcccaaggtggaa tctatcctgttcccagagttgaaaggatataatctgatacttgaaactgttaatgctgat gaaaaactggtttctgactttgtggatcaaactttcgaggtatttcagaaaaatcaagtt ggtccctgcaaatacttaaatgtatacaaaaagtatgatgacttattggacaacacggca gaacaaaacatcactgaattcctgaaagaaaatcatgaaatcgaggattttgtgatgagg atcaatagcattaaaaagcggagaaatgaaattgcatccatgcacataactgtgcctttg gccatgttctgccttgacaccatgaccctaaattatgatctctgtgaacgagcccaaaat cttaaagaccgtttgattcaattccaagtggatgtaaaccgggacaccaacaccagcatc tgtaatcagtacagcctcattgccgacaaagtcagtgagattcctatcaacactggggag ctagtattcctcattgaattcttaaagaaatccagcaatgtcaccgtgttcaaactcagg aggcaacttagagatgcggttgaacggctggagttcttgatggactatgcagacttgtcc caagaggatatcaaactgaacagcactctgttcctctggccagaccagattgaagatatc tttgaaaacagccggaaccttctccttagcaagagggatcaggcagagatggaccttatt aaaaggtgctcagaatttgaagtgaaacttgagggctacagcaaggaactggaaggtttt aggaaacgtgaagtaatgactacagaagaaatgaagaacaatgttgaaaagcttaatgag ctttcaaagaacctagatcaagcactggtggaatttgagttgatcaataaggaggaggag ctgttggaaaaggagaagagtaccttccctcttctgcaaactgtgatggccaacaaagcg ccttatgagcagctgtgggtgacagcctacgagtttagcaccaagtcagaggagtggatg aatggacccctctttttactgaatgctgaggaaatcgcagaagaaatagggaatatgtgg aggacaatatacaaattgaccaagaccttagcggacatgcctgcacctaggcgcttagca gagaatgtgaaaatcaagattgataaattcaagcagcacatccctatcctcaccatttcc tgcaacccaggaatgaaagaccggcactggcagcagatcagtgagattgtcggctatgaa ataaagcctactgaaacgacttgtctctcaaatatgctggaatttggatttggcaaattc attgaaaaactggagcccatcggtgcagctgccagtaaggaatactctctggagaaaaac ttggagaaaatgaagttagactgggttaacatgacgttcaactttgtgaagtacagggac actgatacaagcatcctgtgtgcagttgatgacattcaactgttacttgatgatcatgtg ataaaaacccagaccatgtgtggctctccatttgtcaaaccaatagaaactgaatgccgg aaatgggaagaaaaactagttcgtgtgcaggaaattttggatgcctggttaaagtgccaa gccacttggctgtacctggaaccaatcttcagttcagaggacatcatagcccagatgcca gaagagggcaggaaatttgccatcgttgataattactggaaatcacttatgtcccaagct gtgaaagataccagggttcttatggcagcggaccagccacggatggctgagagacttcaa gaagccaaccttctgttggaggacatccagaaagggctgaatgattacttggagaagaag agactattttttcccaggttcttcttcctatcaaatgatgagctgctggagatattgtca gagacaaaggaccctctccgggtgcagccacacttgaagaagtgctttgaaggaattgcc aagctggagtttacagacagtctggagattgtgggcatgatcagctcagaaaaagaaatc gttccattcaaacagaaaatctacccagctcaagccaaaggcatggtggaaaaatggctc ctgcaggtggaacagatgatgcttgccagtatgaaggaagttattaaacttgggattgaa gcatatgtccaggtcccccgtaatcagtgggtcttgcagtggcctggccaggtggttatc tgtgtctcctccatcttttggacccaggaggtttcccaagccctgattgaaaagacccta ccggattttctgaagaagagcaatgatcagattgcacagattgttcagctggtgcgaggg aagctgagcagtggagctcgactcaccctcggggccctcacagtcattgatgtccacgct cgtgatgtggtaaccaagttatctgaggacaacgtctgtgatctgaacgatttccagtgg atctcccaactgcgctattactgggattccaaggatgtacaggtgcagatgattaccaca gaggccttatacggctatgagtacctgggaaactccccccggctggtgattacacccctc actgaccgctgctacaggacactgatgggggctttgaagctgaaccttggaggagcccca gagggtccagctgggacaggcaagacagaaaccaccaaagatctggccaaagctttggcc aagcagtgtgtggtcttcaactgctctgatggtctggattacaaagccatggggaagttc ttcaaaggactagcccaggctggagcatgggcctgctttgatgagttcaacagaattgag gtagaagtactgtctgtggtagctcaacagattctcagcattcaacaagctattatccgg aagctaaagacattcatctttgaaggcaccgagctctctctaaacccaacctgtgcggtc ttcatcaccatgaaccctgggtatgctggcagggctgagctgccagataacctcaaggcc ttgtttcggacagtggccatgatggtgccagattatgccctcattggagaaatctccctc tactctatgggatttctagactccagaagtcttgctcagaagattgttgcaacctaccgc ctgtgttcagagcaactctcctcccagcatcactatgactatggcatgcgtgctgtcaag tctgtgctcactgctgctggcaacctgaaactcaagtatccagaggagaatgagagtgtc ctgctgctccgggccttgcttgatgtcaacctggccaagttcttggctcaagatgtccct ctgtttcagggaattatatcagacttgtttcctggagttattcttccacagccagactat gcagtttttatggaagtactaaatgcgaacatcaaaaagatgaaacttcagccagtacct tggtttattggaaaaattatccagatctacgagatgatgctggtaagacatggctatatg attgttggagatcccatgggtggcaagacctgtgcttataaagtgttggctgcggctctg ggtgatttatacgaagccaaacagatggaagagtttgctgtggagtataagatcattaat cccaaggctatcaccatggggcagctgtatgggtgctttgatcaagtgagccatgaatgg acagatggtgtccttgccaatgctttccgagagcaagcatcttctttgtctgatgaccgc aagtggattatatttgatgggccagtggatgctgtttggattgaaaatatgaacactgtt ctggatgacaataaaaagctgtgtttaatgagtggagagattatccagatgagtcctaag atgagtctgattttcgagccggctgacctggaacaggcctccccagccactgtgagcagg tgtgggatgatctacatggaaccccatcagctaggctggaagcccctgaaggattcctac atggataccctgccttccagtctcactgaggagcacaaggaattggtcaatgacatgttc atgtggcttgtccagccctgccttgaatttactcgccttcactgtaaatttgtggtccaa acatctcccatccaccttgccttctcaatgatgagactgtactcctctcttcttgatgaa atcagggaaatagaagaggaggaaagtgaattatctgaaggcctgacaagccaacagatc ttcctctggctacaaggtctgttcctttttgccttggtgtggacggtggccggcaccatc aacgcagacagcagaaagaaatttgatctgtttttccgcaacctgatcatgggtatggat aataacaacccaagacccaaaagtgtcaaactcaccaaaaacaacatctttccagaaaga ggaagcatctatgatttttatttcctcaagcaagctagtggacattggtacacatggaca gagtatatcaccaaagaggaggaacatatctccgcaaatgcaaaggtctcagaactcatc atccccaccatggagacagcccgacagtccttcttcttgaaaacctacctggaccatgag attccaatgctgttcgtaggacccacgggcacaggcaaatcggtcatcaccaacaacttc ctacttcgccttcccaaaaatacttatctgcccaactgcatcaatttctctgccagaact tcagccaatcagacgcaggatatcatcatgtccaagctggatcgccggcggaaaggcctt tttgggcctcccatagggaagaaagcagtggtatttgtggatgacctcaacatgccagcc aaagaggtatatggagcacagccccccattgagctcctacggcaatggattgaccatggt tactggtttgacaagaaggataccaacaagctggacatcgttgatgtgctgcttgtgaca gccatgggccctcctgggggaggaaggaatgacattactggacggttcactcgccatctg aatatcatttccatcaatgccttcgaggatgacatattaaccaagattttcagttcaatc gctgactggcacttcgggaaagggtttgatgtggtgtttttaaggtatggaaagatgatg gtacaggcaacgatgacaatttataaagctgcagtggagaatttcctgccaactccctcc aagtcacactatgtctttaacctgcgggatttctcacgggtgatccaaggggtgttgctc tgccctcacacccacctgcaggatgtagagaagtttatccggctttggattcatgaggtt taccgggtcttctatgaccgtctgattgatcatgaagatagacaggtcttttttaacatg gtaagggaaaccacctccaattgcttcaagcagtctgtggaaaaggtcctcatccaccta tcacccactggaaagatagttgatgataatatccgtagcctcttctttggagatttcttc aagccagaaagtgaccaaaagatatatgatgagatcactgacttaaaacagctcacagtg gtcatggagtattacctggaagagttcaacaatatcagcaaggcccccatgtccttggtg atgttcaggtttgccattgagcatatctctaggatctgcagggtcctgaagcaggacaaa ggccacttgctcctggtgggcattgggggcagtgggcggcaaagtgccagcaaactgtcc acattcatgaactcgtacgagctataccagatcgagatcacaaagagctactcaggcaac gattggcgagaggacctgaagaagatcatgctccaggttggggtggccaccaaaagtact gtgttcctcttcgctgataatcagatcaaggacgagtcattcgttgaggacatcaacatg cttctgaacacgggtgatgtgcccaacatcttccccgctgatgagaaggccgacattgtg gagaagatgcaaatggcagccaggacagaaggagaaaagatcgaagtcactcctctttct atgtataacttcttcattgagaaagtgaaaaagaaccttcacattgtccttgccatgagt ccaattggggacgccttccggaaccgcctgcgaatgttcccttctctgatcaattgctgc acaattgattggttccagtcttggcccacagatgccctggagttggtggccaacaaattt ctagaagatgtagagctcgatgacaatattcggatacaggtcatctccatgtgcaaatat ttccaggagagtgtgaaaaagctgtcacttgattattacaacacccttcgaagacacaac tatgttacccccacctcctacctcgaattgatcctaacattcaagacactcctgaataag aagaggcaagaggttgatatgatgaggaatcgatatctgacaggcctgcagaaacttgaa tttgcagcttcacaggtagccgtcatgcaagtggaactgactgccctccaaccccaactc attcagacctctgaggagaccgctaagatgatggtgaaaatcgaggcagagactcaagaa gctgatgccaagaaacttctagtgcaagcagatgaaaaagaagccaatgctgctgctgcc attgctcaaggaatcaagaacgagtgcgaaggggacttggcagaggcgatgccggcgctc gaggctgcgctcgctgcactggacacgctgaacccggcagatatctcgctggtgaaggcc atgcagaacccacctgggcctgtcaagctggtcatggagagcatctgtgtgatgaaaggg ctgagaccagagaggaagccggaccccagtggcagcggtaaaatgatagaagattactgg ggggtatcaagaaagattctcggagacctgaaattcttggaaagtctcaagacatatgac aaagacaacattcccccagtcatcatgaagcggatccgggaaaggtttatcgatcaccca gatttccagcctgctgtaattaaaaatgtatcatctgcatgtgagggtctgtgcaagtgg gtgagggccatggaggtgtatgatcgtgtggccaaagtggtggctcccaaacgggagcgg ctgaaggaggctgaggggaagctggacacacagatgcagaaactgaaccagaagcgagca gagctgaagctagtggaagaccgcctccaggccctgaacgacgactttgaagagatgaat accaagaaaaagacactggagggaaacattgaaatctgttcccaaaagttgatcagggcc gaaaaactgattagtggtcttggaggagagaaagacagatggacagaagccgctcggcag ctgggtatccgttatactaatctgacgggggatgtgttgttgtcctctgggactgtggct tacctgggggcctttactgtggattatcgggctgagtgccagaagcagtggttggcgcaa tgcaaggacaaggtcatccctggctccagtgacttcagtcttagcaacacattaggagat cctgtaaaaattcgtgcctggcagattgctgggcttcccattgactccttctccattgac aatggcatcattgtatccaattccagacgctgggccttaatgattgaccctcaggggcag gccaataagtggatcaagaatatggagaaagcaaataagctgtcagtcatcaagttctcg gatgccaactatgtgaggacgctagaacatgccctgcagtttggtaccccagtcttacta gaaaatgttggggaagagttggatgcctttattgaacccatcttgctcaagtccacattc aaacagcaaggggttgagtacatgaggcttggtgaaaacatcatcgaatactccagagat tttaagttatatatcacaacccgtttgaggaacccacattacctccctgaagtggctgtg aaagtctgtctcctcaactttatgatcactcccttgggcctccaagatcaactccttggc atcgtggctgccaaggagaagccagaacttgaagagaaaaagaataagttgattgtggaa agtgccaagaacaagaaacaactaaaggaaattgaagataagatattggaagtcctttcg ctttctgagggcaacatacttgaggatgagactgccatcaaaattttgtcttcttccaaa gtgctgtctgaagaaatctctgagaaacaggaaattgcttcagtgacagaaacacagatc gatgaaacccgtatgggctacaagccagtggctgttcattctgccaccatcttcttttgt atctctgacctggcccacattgaacccatgtaccagtactccctgacatggttcataaac ctctacatgcagtctctggcccatagcaagaagagcgaggaactggagctacgaattgag tacatcattgatcatttcaccctcagcatctacaacaacgtctgccgctctctgtttgag aaggacaagctgcttttctccctcctcttgacaataggaatcatgaaagagaaaaagcaa attaatgaggaaatttggtactttcttctaactggaggcattgccctggacaaccctttt cccaacccagtttctgagtggctgtctgagaaggcatgggcagaagtggtccgtgcatcg gcactgccaaaactgaaaggccttatggaacatttggaacaaaacggtaatgaatggaag ttcatctatgactcagcctggccccacgaggaaacattccctggatcctggaagtttctt catggtttggagaggatggtgatcctccgatgtttgcggcccgacaaaatgattccagcc attcgggggttcattgctgaacacatgggaagtgtatacattgaagcccctacgtttgat ctccaggggtcctacaatgattccaattgctgtgcaccattgatattcgtgttgtctcca ggcgcagacccaatggcaggcctgctgaaatttgctgatgatcttggcatgggaggtacc aaaacacagaccatctcccttggccaaggccaaggccctattgctgccaaaatgatcaac agtgccatcaaagatgggacctgggtggtcttacagaattgtcatctggccacaagctgg atgcctgctctggagaagatctgtgaggaggtgattgttcctgagagcaccaacatggga ttcagactctggttaaccagctatccatcagagaagtttccagtcagcatcctccagaat gggattaaaatgaccaatgagccccctaaagggctccgggccaatcttttgcgctcttac ctcaatgaccccatctcagaccctgtgttcttccaaagctgtaccaaagcagtgatgtgg caaaagctattgtttggcctttgcttcttccatgccatcgttcaagagaggagaaacttt ggacccctaggttggaatattccttatgaattcaatgaatctgacctgaggattagtatg cgacagatccagatgtttttgaatgattacaaggaggtgccatttgatgctctgacctac ctgacaggggaatgtaattatggaggcagagtaacggatgacaaagataggaggctcctg ctatcccttctgtccacgttctactgtaaggagatcgagcaggaccattactttcttgct cctggagacacttactacatccctcctcatggctcctaccagtcgtatatcgactatctc aggaacctccctatcacagcccacccagaagtgtttggcctccatgagaatgctgacatc accaaagacaaccaggaaaccaaccagctatttcaaggggtgctcctgaccctccctagg cagtcaggagggagtggcaagtcccctcaggaagtggttgaggatctggcccaggacata ctctccaagcttcccaatgaatttgacttggagttggtcatgaagttgtaccctgtggtc tatgaagaatccatgaacactgtcctaaggcaagagctcatcagattcaacagattgaca gcagtggttgacagaagcctcatcgatcttggccgagcaattaaagggcaggttctgatg tcctcagagctggaggacgtcttcagtagcatgcttgtgggtaaagtgccagccatgtgg atggcaaagtcctacccgtcactgaagcccctggggggctatgtggctgacctgctagcc cgcctggccttcttccaggaatggattgacaatggacctcctgtggtcttttggatctct ggattctactttacacagtcttttttgacaggtgtctctcagaattatgctcggaaatac accatccccattgaccacattggatttgagtttgaggtaaccacacaagaaacagtcatg gagagtaacccagaagatggggcctacataaaaggactcttcttagaaggtgcccgttgg gacaggaaaaagatgcagatcggggagtccttccccaaaaccctctatgatccattgccc atcatttggctgaaacctgggaaaagtgcaatgtttctgcatcagaacatttatgtgtgt ccagtctacaaaacaagtgcccggagaggtaccctctccacaacagggcactccaccaac tatgtcctatccattgaactcccaactgacaggcctcagaagcactggataaaccgagga gtagcctctctgtgccagctagataattga

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