Bubalus bubalis (water buffalo): 102410647
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Entry
102410647 CDS
T05912
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00230
Purine metabolism
bbub01100
Metabolic pathways
bbub04024
cAMP signaling pathway
bbub04928
Parathyroid hormone synthesis, secretion and action
bbub05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102410647 (PDE4D)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
102410647 (PDE4D)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
102410647 (PDE4D)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102410647 (PDE4D)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
102410647 (PDE4D)
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
102410647
NCBI-ProteinID:
XP_025126576
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Position
19:18450041..20122621
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AA seq
748 aa
AA seq
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MKRNTCDLLSRSKSASEETLHSSHEEEDPLKGMEPYLVRRLSCRNIQLPPLAFRQLEQAD
LKSESENLQRPTSLPLKILPLIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPM
SQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLT
VIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLL
LDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCD
KHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQGEEEAVADDEESQPEACVIGDPSPDT
NT seq
2247 nt
NT seq
+upstream
nt +downstream
nt
atgaaaagaaatacctgtgatttgctttcccggagcaaaagtgcctctgaagaaacactg
cactccagtcatgaagaggaagaccctttgaaaggaatggaaccctatctcgtaaggaga
ctttcttgccgcaacatccagcttccccctctcgccttcagacagttggaacaagcagac
ttgaagagtgaatcagagaaccttcagaggccaaccagcctgcccttgaagattctaccc
ctgattgctatcacttctgccgactccagtggtttcgatgtggacaatggcacatcttca
gggcggagtcccttggatcccatgaccagcccgggatctggcctgattctccaagcaaac
tttgtccacagtcagcgtcgggagtccttcctgtaccgctccgacagcgattatgacctc
tcgccaaagtccatgtcccggaactcctccattgccagtgacatacatggagatgacctg
attgtgactccctttgcacaggtcttggccagcctgagaactgtacgaaacaactttgct
gcattgactaatttgcaagaccgagcacctagcaaaagatcacccatgtgcaaccaacca
tccatcaacaaagccaccctaacagaggaggcctaccagaaactggccagcgagaccctg
gaggagctggactggtgtctggaccagctagagaccctacagaccaggcactccgtcagt
gagatggcctccaataagtttaaaaggatgcttaatcgagagctcacccatctctctgaa
atgagtcggtctggaaatcaagtgtcagagtatatatcaaacacattcttagataagcaa
catgaagtggaaattccttctccaactcagaaggaaaaggagaaaaagaaaaggccaatg
tctcagatcagtggggtcaagaagttgatgcacagctccagtttgaccaattcaagcatc
ccaaggtttggggtcaaaactgaacaagaagacgtccttgccaaggaactagaagatgtg
aacaaatggggtcttcatgttttcagaatagcagagttgtctgggaaccgacctttgact
gttatcatgcacaccatttttcaggaacgggatttattaaaaacatttaaaattccagta
gacactttaattacatacctaatgaccctggaagatcattaccacgctgatgtggcctac
cacaataatattcacgctgcagatgtcgtccagtcaacgcacgtgctgttgtctacacct
gctttagaggctgtgtttacagatttggagattcttgcagcaatttttgccagtgcaatc
catgacgttgatcatcctggtgtgtccaatcagtttctgatcaatacaaactctgaactt
gccttgatgtacaatgattcttctgtcctggagaaccatcatttggccgtgggctttaag
ttgcttcaggaagaaaactgtgacattttccagaatttgaccaaaaagcaaagacaatca
ttaaggaagatggtcattgacattgtacttgccacagacatgtcaaagcacatgaatcta
ctggccgatttgaaaactatggttgaaactaagaaagtgacgagttctggagttcttctt
cttgataattattctgataggatccaggtccttcagaacatggtgcattgtgccgacctg
agcaaccccaccaagcctctccagctgtaccgccagtggacggaccgcatcatggaggag
ttcttccgccaaggggaccgagagagggagcggggcatggagataagccccatgtgtgac
aagcacaacgcatctgtggaaaaatcacaggtgggcttcatagactatatcgttcatcct
ctatgggagacgtgggcagacctggtccatcctgacgcccaggacattttggacactttg
gaggacaatcgcgagtggtaccagagcacaattcctcagagcccctccccagcgcccgat
gaccaggaggagggcaggcagggtcagacagagaagttccagttcgaactgactttagag
gaagacggcgagtcagacaccgagaaggacagtggaagtcaagttgaggaagacactagc
tgcagcgactccaagacgctgtgcactcaggactcggagtccaccgagatccccctggac
gagcagggggaagaggaggccgtggcggacgacgaggagagccagcccgaggcctgtgtc
atcggggacccctccccagacacgtaa
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