KEGG   Bubalus bubalis (water buffalo): 102411368
Entry
102411368         CDS       T05912                                 
Symbol
DNMT3A
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 3A isoform X1
  KO
K17398  DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub00270  Cysteine and methionine metabolism
bbub01100  Metabolic pathways
bbub04148  Efferocytosis
bbub05206  MicroRNAs in cancer
Module
bbub_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    102411368 (DNMT3A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102411368 (DNMT3A)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    102411368 (DNMT3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bbub03000]
    102411368 (DNMT3A)
   03032 DNA replication proteins [BR:bbub03032]
    102411368 (DNMT3A)
   03036 Chromosome and associated proteins [BR:bbub03036]
    102411368 (DNMT3A)
Enzymes [BR:bbub01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     102411368 (DNMT3A)
Transcription factors [BR:bbub03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    102411368 (DNMT3A)
DNA replication proteins [BR:bbub03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    102411368 (DNMT3A)
Chromosome and associated proteins [BR:bbub03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    102411368 (DNMT3A)
SSDB
Motif
Pfam: DNM3A_N ADD_DNMT3 DNMT3_ADD_GATA1-like DNA_methylase PWWP
Other DBs
NCBI-GeneID: 102411368
NCBI-ProteinID: XP_025117217
LinkDB
Position
12:73560966..73663723
AA seq 957 aa
MPASGPGDTSGSALEREEERKEGEEQEEARAKEERQEPSTTARKVGRPGRKRKHPPVESS
DTPKEPAVTSKSLSMAQDSGPSELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGATE
TPPEASRAVENGCCTPKDGRGAPAEDGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQR
PMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQGSTESQKVEEAS
PPAVQQPTDPASPTVATTPEPVGADAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGF
SWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQP
MYRKAIYEVLQVASSRAGKLFPMCHDSDESDTAKAVEVQNKQMIEWALGGFQPSGPKGLE
PPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEV
RQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGG
REVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRDDWPS
RLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIAS
EVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGL
YEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAK
EVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQG
KDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFA
PLKEYFACVTWSDESCALTSSRQHLEPQVHDTWFRFPPRQAAWRWRRFRFDPGGRTL
NT seq 2874 nt   +upstreamnt  +downstreamnt
atgcccgccagcggccccggggacaccagcggctccgctctggagcgggaggaggagcgc
aaggagggagaggagcaggaggaggctcgtgccaaggaggagcggcaggagcccagcaca
actgcccggaaggtggggcggcctggcaggaagcgcaagcaccccccggtggaaagcagt
gacacaccgaaggagcccgccgtgacctccaagtccctgtccatggcccaagactcaggc
ccctcagagctgttacccaacggggacttggagaagcggagtgagccccagccagaggag
gggagccctgctggagggcagaagggcggggccccagcagagggagagggtgccactgag
accccgcccgaagcctccagagctgtagagaatggctgctgcacccccaaggatggccgg
ggagcccctgcagaagacggcaaagaacagaaggagaccaacatcgaatccatgaaaatg
gagggctcccggggccggctgcggggtggcctgggctgggagtccagcctccgccagcgg
cccatgccgcggctcaccttccaggcgggggacccctactacatcagcaagcgcaagcgg
gacgagtggctggcacgctggaaaagggaggctgagaagaaagccaaggtgatcgcagta
atgaatgctgttgaagaaaaccaggggtccaccgagtctcagaaggtggaggaggccagt
cctcccgccgtgcagcagcccaccgaccctgcatcccccacagtggccaccacgcccgag
cccgtgggcgccgatgctggggacaagaacgccaccaaagcagctgacgatgaaccggag
tacgaggacggccggggctttggcattggggagctggtgtgggggaaactgcggggcttc
tcctggtggccaggccgcattgtgtcttggtggatgacgggccggagccgagcagcggaa
ggcactcgttgggtcatgtggttcggagacggcaagttctcagtggtatgcgtggagaag
ctgatgccgctgagctccttctgcagtgctttccaccaggccacctacaacaagcagccc
atgtaccgcaaggctatctacgaggtcctgcaggtggccagcagccgagcggggaagctg
tttccaatgtgccatgacagcgacgagagcgacactgccaaggccgtggaggtgcagaac
aaacagatgatcgagtgggccctgggagggttccagccctctggccccaagggcctggag
cccccagaagaggagaagaacccctacaaagaagtttacacagacatgtgggttgaaccc
gaggcagctgcctatgcgccgcccccaccagccaaaaagccccgaaagagcacaacggag
aagcctaaggtcaaggagatcattgatgaacgcacaagagagcggctggtgtacgaggta
cggcagaagtgccggaacatcgaggacatctgcatctcttgtgggagcctcaacgtcacc
ttggaacaccctcttttcatcggaggaatgtgccaaaactgcaagaactgcttcctggaa
tgcgcgtaccagtacgatgacgatggctatcagtcctactgcaccatctgctgcgggggg
cgcgaggtgctcatgtgtgggaacaacaattgctgcaggtgcttttgcgtggagtgtgtg
gatctcttggtggggccaggggctgcgcaggcagccatcaaggaagacccctggaactgc
tacatgtgcgggcacaagggcacctacgggctgctgcggcggcgggacgactggccgtct
cggctccagatgttcttcgccaacaaccatgaccaggaattcgaccctccgaaggtttac
ccacctgtcccagctgagaagaggaagcccatccgggtgctgtctctattcgatggaatt
gctacagggcttctggtgctgaaggacttgggcattcaggtggaccgctacatcgcctcc
gaggtgtgtgaggactccatcacggtgggcatggtgcggcaccagggaaagatcatgtac
gtcggggacgtccgcagcgttacacagaagcatatccaggaatggggcccgttcgatctg
gtgattgggggcagtccctgcaacgatctctccatcgtcaaccctgcccgcaagggactc
tacgagggcactggccggctcttctttgagttctaccgcctcctgcatgatgcgcggccc
aaggagggagatgaccgccccttcttctggctctttgagaatgtggtggccatgggcgtt
agtgacaagagggacatctcgcgatttctcgagtccaaccctgtgatgattgatgccaaa
gaagtgtcagctgcgcacagggcccgctacttctgggggaaccttcctggtatgaacagg
ccattggcatccactgtgaatgataagctggagctgcaggagtgtctggagcacggccga
atagccaagttcagcaaagtgaggaccattactactaggtcgaactccataaagcagggc
aaagaccagcatttccccgtcttcatgaatgagaaagaggacatcttatggtgcactgaa
atggaaagggtgtttggcttccctgtccactatactgacgtctccaacatgagccgcttg
gcgaggcagagactgctgggccggtcgtggagcgtgccggtcatccgccacctcttcgct
ccgctgaaggaatattttgcttgtgttacttggtctgatgaaagctgtgctcttacctcg
agtcggcagcacctggagccccaagtgcacgacacttggttccgcttcccaccgaggcag
gcggcctggcgttggcgacgatttcgctttgaccccggcgggagaacactttga

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