Bubalus bubalis (water buffalo): 102414732
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Entry
102414732 CDS
T05912
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102414732 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bbub03032
]
102414732 (TOP2A)
03036 Chromosome and associated proteins [BR:
bbub03036
]
102414732 (TOP2A)
Enzymes [BR:
bbub01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
102414732 (TOP2A)
DNA replication proteins [BR:
bbub03032
]
Eukaryotic type
DNA Topoisomerases
102414732 (TOP2A)
Chromosome and associated proteins [BR:
bbub03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
102414732 (TOP2A)
Centrosome formation proteins
Centriole proteins
102414732 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
102414732
NCBI-ProteinID:
XP_006068686
LinkDB
All DBs
Position
3:22420749..22447060
Genome browser
AA seq
1532 aa
AA seq
DB search
MEVSPLQPVNENMQVSKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ
MWVYDEDTGINYREVTYVPGLYKIFDEILVNAADNKQRDPKMSCIRITIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TASKEYKKMFKQTWMDNMGKAGEMELKPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVYLNGNRLPVKGFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVRFKAQ
IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDD
RKEWLTHFMEDRRQRKLLGLPDDYLYGQATTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTVE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSATDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELETLKRKSPSDLWKEDLAAFVEELEVVEAKEKQDEQIGLPGKGGKA
KGKKTQMVEILPSPSGKRVIPRVTEEMKAEAEKKIKKKIKSENTEGSPQEDGMEMESLKL
RLEKKQKREPVTKTKKQTTLPFKPIKKAKKRNPWSDSESDMSSNESNFDVPPREKESRRA
AAKTKFTMDLDSDEDFSDFDEDTQDDFVPSNASPPKIQTSPKHSNKELKPLKSASSVTEL
DADDAEDNAPPPPSSPAADFPAVTETINPVPKKNVTAKKTAAKSQSSTSTTGAKKRAAPK
KTKKDPDLDSDVSKKLNAPKTKTRRKRKASSSDDSDSNFEKLISKAVTSKKPKEESDDFH
LDLDSAVGSRAKSGRTKKPIKYLEESDEDDFF
NT seq
4599 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccactacagcctgtaaatgaaaatatgcaagtcagcaaaacaaagaaa
aatgaagatgctaagaaaagattgtctattgaaagaatctatcaaaagaaaacacaactg
gaacatatcctgcttcgcccagacacctacattggctctgtggaatcagtgacccagcaa
atgtgggtttatgatgaagatactggcattaactatagggaagtcacttatgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagaatcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgtcgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagcaactatgatgatgaagaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaatttactgtggaa
acagcaagcaaagaatacaagaaaatgttcaaacagacatggatggataacatggggaaa
gctggtgagatggaactcaagccctttagtggagaagattatacatgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaggtctatctcaatggaaat
aggcttccagtgaaaggattccgtagctatgtagatctgtatctgaaggataaggtagat
gaaactggcaatccattgaaaattatccatgaacaagtaaaccacaggtgggaagtatgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgaccaaacttgttgatgtt
gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaaccttcgactcccagacaaaagagaac
atgactttacaagtcaagagctttggatcaacatgccagctgagtgaaaaattcatcaaa
gctgcaattgggtgtggtattgtagaaagtatactaaactgggtgagatttaaggcccaa
atccagttaaacaagaagtgttctgctgtaaaacataacagaatcaaaggaattcccaaa
cttgatgatgccaatgatgcaggaggacgaaactctactgagtgtacacttatcctgaca
gagggagactcagctaaaactttagctgtttcaggccttggtgtggttgggagagacaag
tatggggtttttcctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacaatataattaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactctacgttatggaaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaaacaagaaatggcattctatagccttcctgagtttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggtaccagcaca
tcaaaggaagctaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatat
tccggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaagcagacagatgat
cgaaaggaatggttaactcatttcatggaagatagaagacaacgaaagttacttggcctt
cctgatgattatttgtatgggcaagctaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgaaagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggcagcaataat
ctgaaccttttgcagcccattggtcagtttggtaccaggttgcatggtggcaaggactct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccagca
aaagatgaccatacattaaagtttttatatgatgacaaccagcgtgttgagcctgaatgg
tatattcctattatacccatggtgttgataaatggcgctgaaggaattggtactgggtgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactgttgag
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattctacaacc
attgaaatctcagagcttcccatcagaacgtggacccagacgtataaggaacaggttctt
gagcccatgttgaatggcactgagaagacaccgcctctcataacagattatagggaatac
cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaagctggcggaggca
gagagagctggactacacaaagtcttcaaactccagactagtctcacatgcaactccatg
gtcctctttgaccatgtaggctgtttaaagaaatacgacacagttttggatattctaaga
gacttctttgaactcaggcttaagtattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagagttaattaaagttctgattcagaga
ggatatgattcggatcctgtgaaagcttggaaagaagcccagcaaaaggttccggatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgactctgcaacagat
tctggacctaccttcaactaccttcttgacatgcctctttggtatctaaccaaggaaaag
aaagatgaactgtgcagactaagaaatgaaaaagagcaagagctagaaacattgaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggaggtt
gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca
aaggggaaaaaaacacaaatggtagaaattttgccttctccaagtggaaaaagagtcatc
ccccgagtgactgaagaaatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaatactgaaggaagccctcaagaggatggaatggaaatggaaagcctaaaactg
agactggaaaagaaacagaaaagagagccagttaccaagacaaagaaacaaactacattg
ccatttaaaccaatcaagaaagcaaagaaaagaaacccctggtctgattcagaatcagat
atgagcagtaacgaaagtaattttgatgtccctccacgagaaaaagagtcacggagagca
gcagcaaaaaccaaattcacaatggatttggattcagatgaagatttttcagattttgat
gaagacactcaagatgattttgtcccatcaaatgctagtccacctaagatccaaacttcc
ccgaaacatagtaacaaagaactgaagccactaaagagtgcctcatcagtaacagagctt
gatgctgatgatgctgaggataatgcaccacctcctccaagctctcctgctgcagatttc
ccagctgtaactgaaaccataaaccctgttcctaaaaagaatgtgacagcaaagaagaca
gcagcaaaaagtcagtcttccacctccactacaggcgccaaaaaaagggctgcaccaaaa
aaaaccaaaaaggatccagacttggattctgatgtctctaaaaagctgaatgcccccaaa
accaagactcgccgcaaaaggaaggcatcctcctctgatgattcggactctaattttgag
aaactgatctccaaagcagtcacgagcaagaaacccaaggaggaaagtgatgatttccat
ctggacttggactcagctgtgggttctcgggcaaaatctggaagaacaaagaaacctata
aagtaccttgaagaatcagatgaagatgatttcttttaa
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integrated database retrieval system
