Bubalus bubalis (water buffalo): 102415393
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Entry
102415393 CDS
T05912
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00230
Purine metabolism
bbub01100
Metabolic pathways
bbub04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102415393 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
102415393 (PDE5A)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
102415393 (PDE5A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
102415393
NCBI-ProteinID:
XP_044801998
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Position
7:81156513..81307417
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AA seq
914 aa
AA seq
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MERAGPGSARPQRQWDQDSVEAWLDDHWDFTFSYFVRKGTSSGSTISNAVPVAPLLPRPP
LPRPWRGGEAGVGARPRSTQRQHHAGTFPEEMVNAWFAERVHTIPVCKEGIKGHTESCSC
PLQPSPRAESSVPGTPTRKISASEFDRPLRPIVIKDSEGTVSFLSDSDKKEQMPLTSPRF
DNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLI
SRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPRFNAEVDQITGY
KTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYE
TSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFS
SVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKDKRFPWTNENMG
NINQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEETTGKVKAFNRNDEQFLEAFVIFCGL
GIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSF
SDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCKWILSVKKNYRKNVAYHNWRHAFNT
AQCMFAALKAGKIQKRLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIM
EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIMK
NQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEP
ADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQE
KTLINGESSQTKRN
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atggagagggccggccccggctccgcgcggccgcaacggcaatgggaccaggactcggtc
gaagcgtggctggacgatcactgggactttaccttctcttactttgttaggaaaggcacc
agctccggaagcaccatttccaacgcggtccccgtggctccgctcctcccccgtccccct
ttgccccggccctggcggggcggagaagccggggtaggggcgagaccgagaagcacccaa
aggcagcaccatgccggaaccttcccagaagaaatggtcaatgcatggtttgctgagaga
gtccacaccatccctgtgtgcaaggaaggaatcaaaggccacacggaatcctgctcttgc
cccttgcagccaagtccccgtgcagagagcagtgtccctggaacaccgaccaggaagatc
tctgcctccgaatttgatcggccgcttagacccatcgttatcaaggattctgagggaact
gtgagcttcctctctgactcagacaagaaggaacagatgcctctaacctccccacggttt
gataatgatgaaggggaccagtgctcgagactcttggaattagtgaaagatatttctagt
cacttggatgtcacagccttatgtcacaaaattttcttgcacatccatggactcatctcc
gccgaccgctactccttattcctcgtctgtgaggacagctccaacgacaagtttcttatc
agccgcctctttgatgttgcggaaggttcaacactggaagaagcttcaaataactgcatc
cgcttagagtggaacaaaggcatcgtgggacacgtggctgcttttggtgagcccttgaac
atcaaagacgcctatgaggatcctcgattcaatgcagaagttgaccaaattacaggctac
aagacacaaagtattctttgtatgccaattaagaatcatagggaagaggttgttggtgta
gcccaggccatcaacaagaaatcaggaaatggtgggacattcactgaaaaagatgaaaag
gactttgctgcttacttggcattttgtggaattgttcttcataatgctcaactctatgag
acttcactgctggagaacaagagaaatcaggtgctgcttgaccttgctagcttaattttt
gaagaacaacaatcattagaagtaattctaaagaaaatagctgccactattatctctttc
atgcaggtgcagaaatgcaccattttcatagtggatgaagattgctccgattctttttct
agtgtgtttcacatggagtgtgaggaattagaaaaatcgtcagatactttaacacgggaa
cgtgatgcaaacagaatcaattacatgtatgctcagtatgtcaaaaatactatggaacca
cttaatatcccagacgtcagtaaggacaaaagatttccctggacaaatgaaaacatggga
aatataaaccagcagtgcattagaagtttgctttgtacacctataaaaaatggaaagaag
aacaaagtgataggggtttgccaacttgttaataagatggaggaaaccactggcaaagtt
aaggctttcaaccgaaacgatgaacagtttctggaagctttcgtcatcttttgtggcttg
gggatccagaacacacagatgtacgaagcagtggagagagccatggccaagcaaatggtc
acgttagaggttctgtcttatcatgcttcagctgcagaggaagaaaccagagagctgcag
tccttagcggctgctgtggtaccatctgcccagacccttaaaatcactgacttcagcttc
agcgactttgagctgtctgacctggaaacggcactgtgcacaatccggatgttcactgac
ctcaaccttgtgcagaacttccagatgaaacatgaggtcctttgcaagtggattttaagt
gtgaagaagaactatcggaagaacgtcgcctatcataattggagacatgcctttaataca
gctcagtgcatgtttgcggcactaaaagcaggcaaaattcagaagaggctgacggacctg
gagatactcgcactgctgattgctgccttaagccatgatctggatcaccgcggtgtcaat
aactcatacatacagcgaagtgaacacccacttgctcagctctactgccattcaatcatg
gagcatcatcattttgatcagtgcctgatgatccttaatagtcctggcaatcagattctc
agtggcctctccattgaagaatataagaccaccctgaagataatcaagcaagctatttta
gctacagacctagcactgtacataaagagacgaggagaattttttgaacttataatgaaa
aatcaattcaatttggaagatcctcatcaaaaggagttgtttttagcgatgctgatgaca
gcttgtgatctttctgcaattacaaaaccctggcctattcaacaacggatagcagaactt
gttgccactgaattttttgaccaaggagacagagagagaaaagaactcaacatagagccc
gctgatctaatgaaccgggagaagaaaaacaaaatcccaagtatgcaagttggattcata
gatgccatctgcttgcaactgtatgaggccttgacccatgtgtcagaggactgtttccct
ttgctggacggctgcagaaagaacaggcagaaatggcaggctcttgcagaacagcaggag
aagacactgattaatggtgaaagcagccagaccaagcggaactga
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