Bubalus bubalis (water buffalo): 102415788
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Entry
102415788 CDS
T05912
Symbol
PKM
Name
(RefSeq) pyruvate kinase PKM isoform X1
KO
K00873
pyruvate kinase [EC:
2.7.1.40
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00010
Glycolysis / Gluconeogenesis
bbub00620
Pyruvate metabolism
bbub01100
Metabolic pathways
bbub01200
Carbon metabolism
bbub01230
Biosynthesis of amino acids
bbub04922
Glucagon signaling pathway
bbub04930
Type II diabetes mellitus
bbub05165
Human papillomavirus infection
bbub05203
Viral carcinogenesis
bbub05230
Central carbon metabolism in cancer
Module
bbub_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
bbub_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102415788 (PKM)
00620 Pyruvate metabolism
102415788 (PKM)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102415788 (PKM)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
102415788 (PKM)
05230 Central carbon metabolism in cancer
102415788 (PKM)
09172 Infectious disease: viral
05165 Human papillomavirus infection
102415788 (PKM)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102415788 (PKM)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bbub04131
]
102415788 (PKM)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bbub04147
]
102415788 (PKM)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
102415788 (PKM)
Membrane trafficking [BR:
bbub04131
]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
102415788 (PKM)
Exosome [BR:
bbub04147
]
Exosomal proteins
Proteins found in most exosomes
102415788 (PKM)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK
PK_C
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
102415788
NCBI-ProteinID:
XP_025151996
LinkDB
All DBs
Position
11:83826806..83853179
Genome browser
AA seq
531 aa
AA seq
DB search
MSKHHSDAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRAVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKIYVDDGL
ISLLVKQKGPDFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARASSHSTDLMEAMAMGSVEAS
YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQE
AWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaagcaccacagcgacgccgggacggccttcattcagactcagcagctgcacgca
gccatggccgacacatttctggagcacatgtgccgcctggacattgactccccgcccatc
acggcccgaaacactggcatcatctgtaccatcggcccagcttcacgagcagtggagaca
ttgaaggagatgattaagtctggaatgaatgtggctcgtttgaacttctctcatggaacc
cacgagtaccatgcagagaccatcaagaatgtacgtgaagccacggagagctttgcttca
gaccccattctctatcggccagtggcagtggccctggacactaaaggacctgagatccga
accgggctcatcaagggcagcggcaccgctgaggtggagctgaagaagggagccacactg
aagatcaccctggacaatgcctacatggaaaagtgtgatgagaacatcctgtggctggac
tacaagaacatttgcaaggtggtggatgtgggcagcaagatctatgtggatgatgggctt
atttctctgctggtgaagcagaaaggtcctgacttcctggtgacggaggtagagaatggt
ggctccttgggcagcaagaagggtgtgaacctccctggggctgccgtggacctgcctgct
gtgtcagaaaaggacatccaggatctaaagtttggggtggagcaggacgtggatatggtg
tttgcgtctttcatccgcaaggcttctgatgtccatgaagtcaggaaggtcctgggagag
aaaggaaagaacatcaagataatcagcaaaatcgagaatcatgagggagttcgaaggttt
gacgagatcctggaagccagtgatgggatcatggtggcgcgtggtgatctgggcattgag
atccctgcagagaaggtcttccttgcccagaagatgatgattggtcggtgcaaccgagct
gggaagcccgtcatctgtgccacacagatgttggagagcatgatcaagaagcctcgccct
acccgggcagagggcagtgacgtggccaatgccgtcttggatggagccgactgcatcatg
ctgtccggagagacggccaaaggggactaccccctggaagctgtccgcatgcagcacctg
atagctcgtgaggctgaggcagccatgttccaccgcaagctgtttgaagaacttgcgcga
gcctcaagtcactccacagacctcatggaagccatggccatgggcagcgtggaggcttca
tataagtgtttagcggcagctttgatagttctcacggagtctggcaggtctgcacatcag
gtggccagatatcgcccccgggcccccatcattgctgtgactcggaatcaccagacagct
cgccaggcccacctgtaccgcggcatcttccctgtggtgtgtaaggacccagtgcaggag
gcctgggctgaggacgtggacctccgggtgaacctggccatgaatgttggaaaggcccga
ggcttcttcaagaagggagacgtggtcattgtgctgaccgggtggcgccctggttctggc
ttcaccaacaccatgcgtgtagttcctgtgccgtga
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