Bufo bufo (common toad): 120998091 Help Entry 120998091         CDS       T07950                                  Symbol DST Name (RefSeq) dystonin isoform X1   KO K10382   dystonin Organism bbuf  Bufo bufo (common toad) Pathway bbuf04382   Cornified envelope formation Brite KEGG Orthology (KO) [BR:bbuf00001]  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     120998091 (DST)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:bbuf04812]     120998091 (DST) Cytoskeleton proteins [BR:bbuf04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     120998091 (DST) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin SR_plectin_7 CH Plectin GAS2 Spectrin_2 Spectrin_3 SH3_10 EF-hand_1 Spectrin_4 Spectrin_SYNE1 EF-hand_7 EF-hand_6 EF-hand_5 Spectrin_1st_PEPL Sec3_CC EF-hand_8 DUF2335 Motif Other DBs NCBI-GeneID:  120998091 NCBI-ProteinID:  XP_040284513 LinkDB All DBs Position 4:complement(269928711..270501472) Genome browser AA seq 7509 aa AA seqDB search MIAAAFLVLLRPYSIQCALLLLLLMLGTIATISFLFCWHRKLQKGRHPMKTVFSYRPRSR DALLRSHHFRSEGFRPSPRHLRRYARTRVEETKPLDEVHQSDHDTSSPLRKRKIKRSSRV QPEFYQSVQVTPTRKPSSGTASYRCSMSSSADFSDDEDYSQKSGSASPAPGDTLPWNLPR HERSKRKTSGAAVLDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVGDLYEDLRD GHNLISLVEVLSGDTLPRERDFLKTLRLPREKGRMRFHRLQNVQIALDYLKKRQVKLVNI RNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKEKLLLWTHQATEGYSGIRC ENFTTCWRDGRLFNAIIHRYRPDLIDMDTVAVQSNITNLENAFYVAEKLGVTRLLDPEDV DVSSPDEKSVITYVSSMYDAFPKTPDGGEGISANDVEVKWIEYQNMVNYLIQWIRHHVAL MSDRNFPNTVAELKALYNQYLQFKEKDIPPKEAEKEKIKHLYSLLEAWIEFGRIKLCQGY HPNDIEKEWGKLIIAMFEREKAIRPEIERQEMLQQIANRVQRDSLGCEDKLILARSALQA DTKRMESGIQFQNEAEIAGYLIECENLLRQQLVDVQALVDGKYYQADQLVQRVASLRDEL LSLRNEYSSLYSKGRMIASDQTQLMLSGISQSLNSGFSQSLNPVRNSSMSHNMTPMSPTS LTPSISGSMSPGLLPSVVPGLPSSLATNMSHGFNSHLTPVTPTLAPSFNPGLIPNYATGM NSNALQSLKLMQVKKPLMKSSLADQNLPEEEVNVKFVQDLSNWAEEMQIQLDRGEWGSDL SSIEMHLENHRNFHGVVEEFDTSLKEAKMNELHMSGPLKSSYTDILNKVEGAYSKLLQTS RNRQKNLDSLHSFVARATRELIWLNEKEEEEVAYDWSDRNQNIPAKKDYHADLMRELDHK EEVIKSVQDTAEQLLLQNHPARSSIEAYKAAMQTQWNWILQLCSCVEQHIRQNTAYYEYF SEAKDATEYLKSLKDSILRKYSCDRSTSVHKLEDLVQESMEEKEQLLQYKSTIASLVGKA KTVVQLKPRNPDNPLKASIPIRAICDYRQIEITIYKDDECVLASNSHRAKWKVISPTGNE AMVPSVCFTVPPPNKEAVDSANRIEQMYQSVLSLWHESHVNMKSIVSWHFLMNEIEAIRA TKVSSIKTLLPGEHQQVLGNLKTRFDEFLEDSQESKMFSVSDIGQLEREVNVCKLYYEEL LKSAEREEQEESVYNLYTSEIRNFRLRLESCEGRLIRQIRTLLDRDDLHESALRISEQEK LKKDLDHLKVDLSAISDKCEEFFSQAAASPSIEALRTELNVVVQAMSQVYSMSSIYLEKL KTINLVLKNTQGAESLVKAYETKLCEEDVITADRNTIDRLIATLKQWRTEVDEKREVFHE LEDELQKAKSISDQMFKVHKERDLDFDWHKEKADQIAERWQNVHSQIENRLRDLEGISKS LKYYKESYLALDSWIRQIEDGQSKLQDGISNSKALSKLLDQQKNLISEIEMKQSKIDECQ KYSEQYSLAIKDYELQLMTYRALVDSHQKSPMKRRRFQSSSDVVVQEYMDLRTRYSALLT LVTQFIKFSGETLKRLEEEEKSLEEEKREHVKKAGDILNWVSKVTKTLSKEGGDRERAGM TPTSKHQISSEEILSKQEEISDAVQTLQLLLAKHGDRMSEEERAETENQIKALQESHSLL SREYERQQQEAKELVAKLVEKKVDRVVSGTINEANGRILSIYQSIVEGLVDYETGILLLE VQLIVSGLVCPQLKSCFEIEDSKSHNLIDDQIQVRLHEISHAKSVILSLPPSDLPIITAY NEGLISETVTVKMINTLLSCGCLQLATTGEQLTVNKLFQRNIISTSMFTKLIEREKMAKD FIDPITAEKVTLADLFQRTVTDEKTGMRFLPVNSEDKGKITLKSGRKISVLRAAHEGILE REIMYRLLGAQLFSGGIIDLDSGNQLTLEQAQEQSIIDHGTVCGILTQQVQNGGILCPST RKCVTVDEAVQCNLISYSSALMVLEAQRGFIGLIWPDTSEIFPISTSLQQGLISTELAQK ILSNRHKIAALYIPETSKIVQLDIAAQSGIIEKNTASILSSLELQDKMPNIDVLEPTCKH GLKWISSYESHTAQVNESSENKSEDELTHNPEHTKQLFISYLMVNSYIDANTGERLLLFD GDLDEAASMLLESEHIVRISCGNAGGATDIVGENLQDNETDLSHDVHRNITQSGNASHLN SSFGTESLKNITECLDFMDKVNSKDPEEVICQPFKNVEDNELSNEHKLQHKHTTETHEKI ESFLLKDVIIADVHLGKPSNTIIAVDDKYNSLNQENNTLNNSSEDCHQTGEVYNCPKDTV TTSNISLSESHTEDPVVSFGDPFSDQKMPAKELCDKHPNMSDCAAPPSETNCDTQPNVGQ NISNELYGYFESSSDSDMSDANFESEDEVGYTDENKKTWKTIGNCIIEDRTPTQSDTSSD EDIYYYTDSDVDNTDMLQGRQFLETIIEEDSESNSCLDDQASVHREKSSFPSNSVEEKYE SSKYEAAEKDVAANLKTKDKVTIEEEPDVEYCESSFSETDIDCLVTDDTNSETGYQATEE YSDEYFEDNEIDSKAVLFDFGHSGNERGFHIENVLYPHHVNSGTTSNTDILSQSDEPLHS QGESENINFGNFKTSLSESGLFDGELLETGDKNFIDKDNTETPDLINLKNKSTEEGLDAE DVPVCPKLYNSLDCTDDDDSAPFEQCTDHSQSPKDNRNLNPESFQAEKENASYECSNTNL KAEDNEPFRQSNDQCANQVMEHFTTERSTVQFKNDSESKTDLDLNSEKMIEKYASSKGKA VFDTTVTQTENHCCTEDIESPSKTAQKVTSDLPDNSTCCREKSLSSLETNDTETCIIKIQ EGNSHRESIDKLTSKSPIHIDNLCAIFESSTSKSTSDDLVVTTASAVPEMVQNSNALGMV TSNKGEMDNLTTYLKGCAQIMDTPDHFGYSKQSILRDARSSCKTEENLDGYRKILPQLSC DERNQSKNNSAKDYIHTLDPVNTEARSNNVSKDILVKEGGDYFAQKFGKNNEHLKLLPDL DLVSVKIKSEENRIMIHGDNYQQGKLIDNDTVSCNVEMLQNHKTLSTSSFLSEHKMLEPK HPKLIPSQLDQIFHVPPDSEKSNKFEELIINMNKGLFPSELGLPSSIPEQMNKQIPEQKK SNSPEYHSDDPETVRKFCITEQRCNDVKLLDENPTSQNISVSTAFKVEQNAGDKAVDKVT LTLNQCCQTLNGHLTVVQNQKLHLDNLPVLGDNLETLKIQLEHLESFQSRLTAFSVTLKK DVQFAEQFLTSVPGDLPGEHLKELSENLKKTFATVCEVSSDRAKQIAFAVDAEMGKLAET HRDLLSRLQVLADWITSSNETLDFSVSSDDVDVVKQTMQSLNNLSNDVSEKRVDLEATAF DVQFFISEHAQDLSPNQSKQLLRSLNSTQKSFQDAQKRIVSHMESLKSLLLAAQDLNKQK DAEEQLQEHKDKLQEICDLLTQTENRLIGQQDMLTARDNPADLQHCQAEYEELQKDMQAG ASELAEIVKNTEKFLQEHGDKLSPEEKVIIEQKLKEAKAKFELLRKKAEQSKKELEKAVT TAIKKETEKSAAVEQLEESKSKIESLLDWLSHVDEEAENGNQDKKSHIKENGTHRKDNEI QSILDGVQEVNGNLIVCDGKSNFMNVQQSKEEDLNSQYEKVKAQHEKIVAQHQAVIITTQ SAQALLEKQGRHLTPEEKEKLQKNIEALKAQFESALSDSERKMKAIQTVQEELEKFTADY SEFENWLQDSKHELENLESGAEDFASLVTKLQRQKSFSEDVISHKGDLRYITISGQRVID AAKSCSKDDVEEDNNNISTMETCKMVQSKLDIASEDFKSLHAKCNLLGNNLKDLVDKYEH YKEASCGLLSGLQKSESAVQKRLSEPIAADTRNLQRQIEDTKLLCEQVSVHQVGVEKLKK AAEGILNTKVGLLLNKDEIQKPLDDIVGRCDDLSQSVSDWNEKLQITLTRSLSVQDGLDE MFDWMQSVERDLKEHQQVPLNSSSIQEMISKNNMLEQDIVSRQSSISAMNEKVKKFMETA DPSSASSLQGKMNDLSERFSKATEQTRARTEKMEDLKTKVEQFEDLSGKVQSFLDKKLKA LNEVDGPGKDVTELSQFMQETSKEILEQKKSVEDLHKLVDELCVYALPGDKSLVLEKVNS ILKQFQDLEETVKAKEEDVSSCQAQMDSFQSLVQSLKHWFTLVNDRIPAQRLTPCVDDLS KQLTDMKNLQEEWTLKGKDVQKVNSKGTALCNLINAVTSPAKNRASMKSGRSIVNGSVSS DVKERLTNKELAVVQKGMLDVNEGYEHLGNILKDKVCDAEGRLSQLQQVHDETSSLMQWL EKMHSTAIAWEAPTDSESVRSQVQQHKIFAAEVKKNERKVDALEDKLKNVIENYGDASES QKWKDMLDKIDTSWKDITKMTAERQRTLEESSNDLTLFQNAEAQLKQWLVEKELMASVLG PLSIDPNMLKTQKQQVQILLKEFDARKQQYEQLNCTGQRILSRPGDLPPCDEAVKKQLAD VACKWEGLTGQLHDRCNQIDQAIVKSTDYQNHLNGLSEKLSALNNKLSSNMTLSSDPSAV KLKLETAKQVQEEIKQEMPTIESARVLCDELSHLVAEEYLKVELNRQMDNIVKPFMDLKE KTAAHVEQLQSAFVSSQKFHQLSEDFQTWIENTKKEQKEAAPISAKPDILKSAITETKQM QNTVNSQQDAFEKVMEEGEKLLQKTEGEGKVKLQSQLSMLKCEWEDINRQISNRVSHLID CQQKAIKYRDLVDNILPWVEEHQNKVCELRPSVDDEAIEKSIAEVKVLQKSVDKQRGMLE MLKSAADSLLASCQVDKEIVTDESNMLNNKMESLIDNLQNKRDTLENMALRLKDFQESMK EAENQLVAAQDHLEIHDSLGAKACSNKHLTIMQTQQKALQGLKPQVERCKRMAQELVVEA LDAQGVSDLLLQAESLQQKHKTISEQVDEKCSFLETKLQGIGHFQNSIREMFAQFAELDD ELDSMSPVGRDRHILQAQKQDISKFLQKLGALITTNDNANKTCKMMLTTESSPDLIGIKR DLEALNKQCNKLLDRGKSREENIDDTITRIEEFYSTLRQFVDQLGTVEEHEESQGAVGME TDIINHQLNVFTTFQKEEIEPLQAQLQEVNWLGQGLVQSAAKNTSTSNLEHDLEEVNARW NTLNKKVAQRAAQLQEALLHCGRFQDALESILSWLTDTEELVANQKSLSAEYKVVKAQIQ EQKLLQRLLDDRKPTIDVIKREGEKIAGTADQTDKDKILKQFSALERRWDELLKKAETRN RQLDGILVVAKQFHDTLEPLSDWLSNSEKKLANSEPIGTQTPKLLEQIAQHKALQEDISA HSTILHQSLSIGQSLKALSSREEKEMVQEKLDICQTRFMEVQERSSRREELLHQAHCNAQ IFGDDEVELMNWLTEVHDKLSKLSVQDHSADVLTRQHTELLLLQEDILLRKQNVDQAIQN GLELLKHTTGDEVVIIQEKLDGIKSRYSEITKLSFDVSKVLEQALNLATQFHSTHDELGR WLDKVEVELKDYEIQDQKPEEMNAVQQRKKELLLEARTYKALLDSLNEVSSSLLELVPWR ARGGLGKMVTEDNERYRSVSDTLTQMVEEIDAARLRSQQFEQAVGAEHTWSEDTKNKMMA LGHIRLEQDQTVAQLQVQKGFTMEILRHKDTIDELVKSGHEILSSYSEDEKQPMLNKLTK LAKSYDNICHLNAERNLQLERAVCLVNQFWETYEELWPWLTETEKVISELPPPALNYDTL REQQEDIRQLRELIAEHKPHIDKMNKTGPQLLELSPEEGFFIQEKYITADTLYSDIKEVV KKHAVALDEAVSQSSQFHDKIDPTLESLERIAERLRQPPSISAECEKIREQISENKNVSV ELEKLQPVYETLKMRGDEMIARSEGADKDISAKAVQDKLDQMVFIWEDIQALTEEREAQL LDVMELADKFWCDHIALLATIKDTQEFIRELEEPGVDPSVVKQQQEAAEAIKEEIDGLQE ELDIVTTLGSELISACGEPDKPVVNKNIDELNSSWEMLNKTWKERVDKLDDAMQAAVQYQ DGLQTLFDWVDISMGRIEAMPPIGTDLETVKQQMAELKQFKTEAYQQQIELERLNHQKEL LQKKATDENDKLAVEDSFKELKHLWQALEDKIINRQHKLEGALLALGPFQHALDELLTWM THTEGLLNEQKAIGGDPKTIEIELAKHHVLQNDVLAHKSSVETVQKAGNDLIESSAGEEA SSLQSRLEALSQRWQNVLDKTEQRRKQLDSALFQAQGFHNEIEEMHQWLSETERHLLASK PLGGLPETAKEQLDTHLELCAAFEAKEHVYESIMLKSQQMMQRCLDEPEANMDQDINNLK EKWESVETKLSERKVKLEEALSLATGFHNSLQDFINWLTQAEQTLTMASPPSLVLDTVLF QIDEHKVFVTEVNSHKDQIMELDKTGNQLKYFSQKQDVVLIKNLLISVQSRWENVVQRSL ERGRALDDARKRSKQFHEAFTKLMEWLEESETSLDSELEIANDPDKIKTQLVQHKEFQKT LGVKHSVYDTTTRSGRSLKEKAALSDDIHKLDDMLSEIRDKWDTVCGKSVERQNKLEEAL LFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDIVMNLIDNHKVFQKELGKRSNSIQA LKRSSRELIEGSRDDPSWVKAQMQELSTRWETVCTLSVSKQTRLEEALRQAEEFHSAVHT LLEWLAEAEQALRFHGVLPDDEESLKSLIDQHKEFMRKVEEKRSELNKGASMGEAILSIC HPDSFTTIKHWITIIRARFEEVLTWAKQHQQRLAFALEELIAKKELLESLLQWLQWAETT LNEKDKEDIPEEIDEVKALIAEHQAFMEDMTRKQPDVDKVTKTYKRKAPELTTGQSQIPV LGKGRTGRKRSPTPNLYPSGAQSSIETKNPRVNLLVSKWQQVWLLALERRRNLNDALDRL EELREFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIEGILSSKFPT SRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPVTDADKIEDEVTRQVAKCKCAK RFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVH HHGSKMLRSESNSSITTQPLIAKGRTNLELREKFMLPEGISQCMTPFRPKGRRSRPSSRG ASPNRSSSSPNVQASPSQATGISTPKTPLHITRNYGKPWLTNSKTSTPCKSPESPEQRLS SEEGTPIQGSKLRLPGYLSGKGFHTTEDNSLLTTAASKVRTQFADYRKTPSRPGSKAGSR SSSRRGSDASDFDISDIQSVCSDMSETVHESSRPSPRASSRSSTGRPSKIPTPQRRTPIS KLATKSTKR NT seq 22530 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgctgccttcctggtgctgctcagaccctacagcatccaatgtgccctgctg ttactgctcctcatgctgggcaccatcgccaccatctccttcctcttctgctggcaccgc aagctccagaagggcaggcaccccatgaagacggtgttcagctaccggccccggagcaga gatgccctcctgagatcccatcatttccgctcagagggattcaggccaagccctcgtcac ttgcggaggtacgcccgaacccgtgtcgaagagacaaagcccttggatgaagtccaccag agtgaccatgatacatcttcacctctaagaaagcgaaagatcaagagaagcagccgggtt cagccagaattttatcaatccgtgcaagtaacccccactcgaaaaccgagctcgggcacc gcgtcctatcgctgctccatgtcctcctccgctgacttctcggatgatgaggattacagt cagaaatcaggatctgcttcccctgccccgggagataccctgccctggaacctgccccgg catgagaggagcaaaaggaagacgtcgggggcagcggtgctggacccggcagagagggca gtgctcaggatagctgatgaaagagacaaagtacaaaagaagacattcaccaaatggatt aaccagcaccttatgaaggtacggaagcatgtaggagatctgtatgaagacctgcgagat ggacataacctgatctcgttagtagaagtactctctggagataccctgccaagggaacga gattttttgaagacattacggttgcccagagaaaaaggccgaatgcgctttcacagacta cagaatgtacaaattgcacttgattatttgaaaaaacgccaggtgaagctggtgaatata agaaatgatgacataacagatggaaatcccaaattgactttgggcttaatatggaccatt attctgcactttcagatttctgacatccatgttactggagagtcagaggatatgtcagcc aaagagaagcttcttctttggacgcatcaagcaactgaaggctacagtggaattcgatgt gaaaactttaccacatgctggcgagacggacgactctttaacgccatcattcatagatac aggccggacctgattgacatggataccgttgctgttcaaagcaacattacaaacttagaa aatgctttttatgtagctgaaaaactgggtgtcaccagactgctggatccagaagacgta gatgtttcttctccagatgaaaagtcggtgattacatatgtttcttcaatgtatgatgct tttcccaagacaccagatggaggggaaggaattagtgcaaatgatgttgaagtaaaatgg atagaatatcagaatatggtgaattacctcatccaatggattaggcaccatgtagcgtta atgtctgacagaaattttccaaacactgttgcagaactaaaggcactttataaccaatac ttgcagtttaaagagaaagacatcccaccaaaggaagcagaaaaagaaaagatcaagcac ctgtactcactgctagaagcttggattgaatttggacgcatcaagctttgtcagggatat catccaaatgacatcgaaaaagaatggggaaagctaatcatcgctatgtttgaacgggag aaagcaattagaccggaaattgaaaggcaagagatgctgcaacagattgcaaaccgagtg cagagagatagtcttggatgtgaagataagctgatattagctcggagcgctcttcaagct gacactaaacggatggaatctggaatccagtttcaaaatgaagctgagattgctggttac ctgattgaatgtgaaaatctactgcgacagcagcttgtggacgtccaggcgcttgtagat ggaaagtattatcaagcagaccagttagtgcaaagggtggcttctttgcgggatgaacta ctgtcattaagaaatgaatactcctcgttatacagcaagggacggatgattgcgtctgat cagacacaacttatgttatcaggaatatcacaaagcctaaactcaggattttcacaaagc ttgaaccctgtaagaaactcttcaatgtcccacaatatgacaccaatgtcacccaccagc ctgactccaagtatatctggcagcatgtctcctggtctcctaccaagtgttgttcctggt ctgccatccagccttgccaccaatatgtctcatggctttaattcacatttgactcccgtg acaccaacacttgcaccaagctttaacccaggtttaatcccgaactatgcaactgggatg aactcaaatgcattacagtcactcaagctcatgcaagtcaagaaacccttgatgaaatca tctcttgctgatcaaaatttgcccgaagaagaagtgaatgttaaattcgttcaagacctc tcaaactgggcggaagaaatgcagatacaactggaccgcggagagtggggttcagacttg tccagcattgagatgcatttagagaatcacaggaacttccatggggttgttgaagaattt gataccagtcttaaagaggccaaaatgaacgagctccacatgtcaggtcctttgaaaagt tcttatactgatatcctcaacaaagttgagggcgcctattcaaagttactgcaaacatca agaaaccgtcaaaagaacctggactcccttcacagttttgtcgcaagagccacaagggag ctgatatggctgaatgaaaaagaagaggaagaagtagcctatgactggagtgatagaaac caaaacataccagctaagaaggactatcatgctgatttaatgagggaacttgatcacaag gaagaagttattaaatctgtgcaagatacggcagaacagttgttgctccagaatcatcct gcaagatccagtattgaggcctacaaagcagctatgcagacacagtggaactggattctg cagctgtgcagttgtgtagagcaacacatacgacaaaacactgcctactatgagtatttc agtgaagccaaagatgccacagaatacctgaagagcttaaaagattccatactgaggaag tatagctgtgatagatcaaccagtgtgcataaactggaagacttggtgcaagagtcaatg gaagaaaaggagcagcttttgcagtacaaaagcacaattgccagccttgttggaaaagca aagacagtagttcaattaaagccaaggaaccctgacaatccactgaaagcatctattccg attcgagctatatgtgactacagacaaattgagataactatttacaaagacgatgaatgt gtactagcaagcaattcccaccgtgcaaagtggaaggtgatcagtccgactggcaatgaa gccatggtcccatctgtgtgctttacagtgccaccaccaaacaaagaagctgttgactcc gcgaacaggattgagcaaatgtatcaaagtgtattatctctttggcacgaatcccatgtc aacatgaagagcatagtgtcttggcatttcctaatgaatgaaattgaagccatccgagct accaaggtttcttcaattaaaactttgcttcctggagaacatcagcaggttctgggcaat ctgaaaactcggtttgatgaattcttggaagacagccaggagtcaaagatgttttctgtg tctgatataggacagctagagagagaggtcaatgtctgcaaactatactatgaggagctt ctaaaatctgcagagagagaggaacaagaagaatctgtttacaatctgtatacctctgag atcagaaacttccgtcttcggctggaaagctgtgagggacggcttattcggcaaatcaga acactgctagacagggatgatctgcatgaaagtgcactgagaatctctgaacaagagaaa ttaaagaaggacttggaccacctgaaagtagatttatcagcaatttcagataaatgtgag gagttcttcagccaagctgctgcctctccatcaattgaggctctacgaactgaactcaat gttgttgtccaggctatgagtcaagtctactccatgtcatccatttacctagaaaaatta aagactataaatctagtgctcaagaatactcaaggagcggagagcctagtgaaagcatat gagaccaaactatgtgaagaagatgtcattacagctgatagaaacacaattgatagactg attgccaccttgaagcaatggagaacggaggtggatgaaaaaagagaagtgtttcatgaa ctagaagatgaattgcagaaagccaaaagcatcagtgatcaaatgttcaaagtgcacaag gagcgggatctggactttgattggcacaaagaaaaggcggaccagattgctgagcggtgg cagaatgtacattctcagattgaaaacaggttaagagacctggaaggaataagcaagtct ctaaaatattacaaagaatcttacttggcacttgattcctggattaggcaaatagaggat ggacaaagtaagttgcaggatggcatctccaatagtaaggccctttccaaacttttggac caacagaagaatttgatttctgaaattgagatgaaacaaagcaaaattgacgaatgccag aagtattctgaacagtattctctggctattaaggactatgaattacagctgatgacttac agagcactcgtggactcgcatcagaaatctccaatgaaacgtagacgcttccagagctca tctgatgtcgttgtacaagagtatatggatctaaggacccgttactctgccttgctgact ttagttacccagtttataaaattttctggagaaactttgaaaagattggaagaagaggag aaatcattggaagaggaaaaacgagagcatgtaaagaaggcaggtgacatactgaattgg gtgtctaaagtcactaaaactctaagtaaagaaggaggagacagagagagagcaggaatg acacccacttctaagcaccagatttccagtgaagagattctgtcaaagcaggaagagatt tcggatgctgtgcagacgttacaattgcttttagctaagcacggtgacagaatgtctgaa gaagaaagagcagaaacagaaaatcagatcaaagcactccaagaaagccacagtctgtta tcaagagagtatgaaagacagcaacaagaagccaaggagctggtagctaaactggtggaa aagaaggtggacagagttgtgtcagggactattaatgaggcaaatgggagaattctttcc atttaccagtctattgttgaaggacttgttgattatgaaacaggaattcttctacttgaa gtacaacttatagtgtctggactggtttgcccacagttaaagagctgctttgaaattgaa gattctaagagtcataatcttatagatgatcaaattcaagtgcgactccatgaaatatct catgctaaaagtgtgattttatctctccctccaagtgatttacctataatcacagcttac aatgaaggattaatttcagagactgtaacagtcaaaatgatcaacactttgctttcttgt ggctgtcttcaacttgccactacaggagagcaactcactgtaaacaagcttttccaaagg aatattatttctacgtcaatgtttacaaagcttattgagagagagaaaatggccaaagat ttcattgatcccattactgcagaaaaggtgacattagcagacctgttccagaggactgtg acagatgagaaaacaggaatgagatttcttcccgttaactctgaagataaaggtaaaatc acattaaaatctggaaggaaaattagtgtattacgtgcagcacatgaaggaattctggaa cgagaaattatgtacaggctacttggtgctcagcttttctcaggtggtattattgaccta gacagtggaaatcaactgactttggaacaagctcaagaacaaagtattatcgatcatgga acagtttgtggaattttaacccaacaagttcaaaatggtggaatcctttgcccatctaca agaaaatgtgtaacagtagatgaagctgttcagtgtaatttaatatcatatagtagcgca ttaatggtcctagaggcacaaagaggttttattggactaatatggcctgatactagtgaa atattccccatatcaacatctttacaacaaggattaatttctactgagttagcgcaaaag atcctaagcaacagacacaaaattgctgcgttatatattcctgaaacatctaagattgtc caattagatatagctgctcagtctggtataatagaaaaaaacactgcatccatcctcagc agcttggaattacaggacaaaatgccaaacatagatgttctggaaccaacctgcaagcat ggtctaaagtggatatcttcttatgaatcccacacagctcaagtaaatgaaagttctgaa aacaaatcagaggatgaactgacacataatccagagcataccaagcaattatttatttct tatctaatggtaaatagttatattgatgcaaatacaggagaaagactattactgttcgat 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actgagcagaggaggaaacagctggacagtgcattattccaggctcaaggtttccacaat gaaattgaagagatgcatcaatggctgtcagagactgaacgtcatttactggcttccaag cctcttggaggattaccagagacagcaaaagagcagctcgacactcatctggaactgtgt gctgcgtttgaagccaaagaacatgtatacgaaagcataatgcttaaaagccaacagatg atgcaaagatgccttgatgagccagaggcaaacatggaccaagatattaataacctaaag gagaaatgggaatcagttgagacaaaactcagtgagaggaaagtaaaattagaagaagct ctcagtttggccacaggttttcacaattctctccaagactttattaactggctaactcaa gcggagcagactctcactatggcttccccaccaagtcttgttttggacacagtattattt caaattgatgaacataaggtgtttgttacagaagtgaactcacacaaagatcagataatg gagctggataaaacgggcaaccaattaaaatatttcagccaaaaacaagatgtggtattg attaaaaatttactgatcagtgtacagagccggtgggaaaatgtggtacagcgttcactg gaaagaggacgggccctcgatgatgctcgcaagcggtcaaaacagttccatgaggctttt actaaacttatggaatggcttgaagaatccgaaacatctttagactcagaattagagatt gcaaatgacccagataaaattaagactcagctggtacagcataaggaattccagaaaacc ctgggagtcaagcattcagtctatgataccaccacaagaagcggccgctcactgaaagag aaagctgcgctgagtgatgatatccacaaacttgacgacatgctcagtgagataagagac aaatgggacactgtctgtggaaaatctgtggaaaggcaaaacaagctagaagaggcacta ctgttttccggccagttcacagatgctttgcaggcccttattgactggctgtacagagtg gagccacagcttgctgaagaccaacccgtgcatggggacattgacattgtgatgaacctc attgacaaccacaaagtttttcagaaagagttgggcaagcgaagcaacagtatacaggca ctgaagcgttcgtctagagagttaattgaaggaagtcgtgatgacccttcttgggtaaaa gcccagatgcaggaattaagcacccgctgggaaactgtgtgcactttgtctgtgtccaaa cagacccgactagaagaagcactgcgccaggcagaggaattccactcggcagtacatact ctgctggagtggctggcagaagcagagcaagctttgagattccacggtgttctccctgat gatgaagagtctctgaagtcgctcatagaccagcacaaggaatttatgagaaaagtagaa gagaaaagatcagagctgaataaaggagcaagtatgggagaagctatactttcgatttgt cacccagattcttttactacaataaagcactggataactatcatcagagccagatttgaa gaggtcttaacatgggcaaaacagcatcaacagagattggcttttgctttggaagaacta atagccaaaaaggaacttctggagtctttactccagtggttacagtgggcagagaccaca ctgaatgaaaaagacaaggaggacatacccgaggagatagatgaggttaaggctctgatt gcagaacatcaggcttttatggaagatatgactagaaagcagccagatgtagataaagtt acaaagacttacaagaggaaagctcccgagcttacaacaggtcaatctcaaatccctgtc ttaggcaaaggaagaacaggccggaagcgttcaccaactcctaacttgtacccatctggt gcacagtcatcaatagaaactaaaaacccaagagtgaacttgctggtcagtaaatggcaa caagtgtggcttttggcattagagaggagaaggaacttaaatgacgctttggataggctg gaagagctacgagaatttgccaactttgattttgacgtgtggagaaaaaaatatatgcga tggatgaaccacaaaaaatcccgtgtcatggacttcttccgaagaattgataaagatcag gatggaaaaataacacgtcaagaattcatagaaggaattctgtcttcaaaattccctacc agtcgtctggaaatgagcgccgtagctgacatctttgaccgggatggtgatggttacatt gactattatgagtttgtggcagcccttcaccccaacaaagatgcttacaaacctgtaact gatgcagacaaaattgaagatgaggttacacgacaagttgcaaaatgcaagtgtgccaaa cgcttccaagttgagcaaattggggagaacaaatataggttcttcctgggaaatcagttt ggagactcccagcaacttcgccttgtccgtattttgcggagcacagtgatggttcgagta ggtggtggttggatggcactggatgaattcctagtgaaaaatgatccatgtagagttcat catcatggaagtaaaatgttacgttcggaatcaaactcttcaattactactcagcctctt atagctaagggaagaactaacttagaattgcgagaaaagtttatgttacctgaaggcata agtcagtgtatgactccattccggcctaaaggtcgaaggtcaagaccgtcttcaagaggc gcatcacccaacagatccagctcaagtccaaatgttcaagctagtccatcacaagccaca ggcattagcacccccaagacacccctccatataacacgcaattatggtaaaccttggttg acaaacagcaaaacatcaactccttgtaagagccctgaatcccctgaacagagactgtca tctgaagagggaactcctatccagggaagcaaattaagacttccaggatacctgtccgga aaaggattccatactacagaggacaacagtttattaactactgcagcatctaaagtcaga acacagtttgcagattatcggaaaactccaagccgaccaggaagcaaggccggaagcagg tcaagtagccggcgaggcagtgatgcctctgattttgatatttcagacatccaatctgta tgttctgatatgtctgagactgttcatgaaagcagcagaccctctccaagagcaagttca agatcttccacaggtagaccttcaaaaattcccaccccacaacggcggacacctatcagc aagctagcaaccaaatcgacaaaaagatag

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