KEGG   Bufo bufo (common toad): 120998995
Entry
120998995         CDS       T07950                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf00562  Inositol phosphate metabolism
bbuf01100  Metabolic pathways
bbuf04020  Calcium signaling pathway
bbuf04070  Phosphatidylinositol signaling system
bbuf04081  Hormone signaling
bbuf04082  Neuroactive ligand signaling
bbuf04261  Adrenergic signaling in cardiomyocytes
bbuf04270  Vascular smooth muscle contraction
bbuf04310  Wnt signaling pathway
bbuf04371  Apelin signaling pathway
bbuf04540  Gap junction
bbuf04621  NOD-like receptor signaling pathway
bbuf04912  GnRH signaling pathway
bbuf04916  Melanogenesis
Module
bbuf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120998995 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    120998995 (PLCB4)
   04371 Apelin signaling pathway
    120998995 (PLCB4)
   04020 Calcium signaling pathway
    120998995 (PLCB4)
   04070 Phosphatidylinositol signaling system
    120998995 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    120998995 (PLCB4)
   04081 Hormone signaling
    120998995 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    120998995 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    120998995 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120998995 (PLCB4)
   04916 Melanogenesis
    120998995 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120998995 (PLCB4)
   04270 Vascular smooth muscle contraction
    120998995 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbuf04131]
    120998995 (PLCB4)
Enzymes [BR:bbuf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120998995 (PLCB4)
Membrane trafficking [BR:bbuf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120998995 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120998995 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 120998995
NCBI-ProteinID: XP_040285803
LinkDB
Position
4:534334226..534712302
AA seq 1227 aa
MAKPYEFNWQKPVPSFMQDGAMFDRYEEESFAFEPNCLFKVDEFGIFLTWKSEGKEGQVL
ECSLINSIRYSIAPKDPKILSALEAVGKAENELEGRIVCVCSGTDLVNINFTYMVAESVE
LAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNVNGKIPVRSITRTFASGKTEK
VIFQVLKELGLPSGKNDEIEPSAFTFEKFYELTQKICPRTDIEELFKKINGDKSDYLTVD
QLVSFLNEHQRDPRLNEILFPFFETKRAMQIIETYEPDEELKRRGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGRSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEEIFGDLLLKQPLETHPEYVTAFNKQGKGKHAQLTHELDPGRSLPSPNDLKRKILI
KNKRLKAEVEKKQLEALKSVMEAGETVAPVSILEDDIEEETENADQEEEAHPEFKFGSEL
SADDLSQKEAAANIAKKVAEDAEQENNNKKGAITADDEQAWMANYKYVGATTNIHPFLST
MINYAQPVKFQGFKLAEERNIHFNMSSFNESVGLGYLKTHAIELVNYNKRQMSRIYPKGG
RVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTF
DPFSETPVDGVIAATCSVQVISGQFLSDKKMGTYVEVDMYGLPTDTIRKEFRTRMVMNNG
LNPVYNEEAFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNK
PLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPN
DNTKNDKKGKTNNAKANVTPQTSSELRPSAASSSGIAIEAKKGIDLIPQVKVEDLKQMKA
YVKQLKKQQKEINSMKKKHDKEQSAVRKVHCTQADKLVAQLDKEKLSLEKNLEKAIKKKG
GNNCVEMKKETENKIQVLTSDHKSKVKEIVAQHTKEWSELLSTQAADVQNLQDLHLSQQC
ELLKKLLITVQEQQTQQLKLSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRV
RELNSSNTKKFLEERKRLAMKQSKEMDQLKKAQLEHLEILEKQNEQLLKSCHAVSHSQGK
GNPADGQTGSRDGPQASNSCVKLQNAN
NT seq 3684 nt   +upstreamnt  +downstreamnt
atggccaaaccgtacgaattcaattggcagaagcctgttccttctttcatgcaagatgga
gcgatgtttgacagatacgaggaggaatcatttgcatttgaaccaaattgcctctttaaa
gtggatgagtttggcatctttcttacatggaaaagtgaaggaaaggaaggccaagtcttg
gaatgctcgctaatcaacagtatacgttatagcatagcaccaaaggatccaaaaatactg
tctgcactggaggctgttggaaaagcggaaaatgaactagaaggccggatagtgtgtgtg
tgctctggtacagacctggtgaacatcaactttacttacatggtagcagagagtgtcgaa
ttagctaagcaatgggtagaagggctaaaatctatcacgcataattttagagccaacaac
gtcagtccaatgacatgtctcaaaaaacactggatgaaactcacatttctcacaaacgta
aatggaaaaatcccagtccgaagtattacaagaacttttgcctctggaaaaacagaaaaa
gtgatttttcaagttcttaaagaattaggtcttccaagcggaaagaatgatgagatcgaa
ccctctgcttttacatttgagaagttctatgaactaacacaaaagatttgccccaggact
gatatagaagagctgtttaaaaaaatcaatggagacaaatctgattatttaacggtagac
caattagtgagctttctaaatgaacatcaaagagaccctcggctcaatgaaatcctgttc
ccgttttttgaaacaaagcgggccatgcagatcatagagacatacgaacctgatgaagaa
ttgaagagaagaggtctcatatcaagtgatgggttttgcagatatttgatgtctgacgag
aacgcccccgtctttttagaccgcttggagctgtaccaggagatggagcacccacttgcg
cactacttcataagctcctctcataatacataccttaccggaagacagtttggaggccga
tcgtcagtagagatgtatagacaggttcttttagctgggtgcaggtgtgttgagctggac
tgctgggatggaaaaggtgaagatcaggagcctatcatcacgcatgggaaggctatgtgt
acagatatcctctttaaggatgtaatccaagccatcaaggagactgcgtttgtcacgtcg
gaatatcccgtaatcctttcatttgagaatcactgcagtaaatatcaacagtacaagatg
tccaaatactgtgaagaaatatttggggatctcctgctgaagcagcccctggaaacccat
ccggaatatgtcactgcattcaacaagcaaggcaaaggaaagcatgctcagctcactcat
gaactagatcctgggagatctttgccttctccaaatgacctgaaaagaaaaattctcata
aaaaacaagcgactgaaggctgaggtggaaaaaaaacaactggaggctttaaaaagcgtg
atggaggctggggagacagtggcacctgtcagcatccttgaagatgacattgaagaagaa
actgaaaatgctgatcaggaggaggaagcccaccctgaattcaagtttggaagtgagctc
tcagcggacgatcttagccaaaaagaggctgcagcaaacatcgcaaaaaaagtagcagaa
gatgccgagcaagaaaacaataacaaaaagggcgcaataaccgcagatgatgaacaagca
tggatggcaaattataaatacgtaggcgccactaccaatatacatccgtttttatccaca
atgatcaactatgcgcaaccagtaaaatttcaaggtttcaaactggcagaagaacggaac
attcatttcaacatgtcgtccttcaatgaatcggtggggttgggttatttgaagacacac
gctatcgagttggtaaactataacaaacgtcagatgagccgaatctaccccaagggtggg
cgagtggattccagtaattatatgcctcaaattttctggaacgccggctgccagatggtc
tctctgaactatcagaccccagatctagcaatgcagctgaaccaggggaagtttgaatac
aatggatcctgtgggtaccttctaaaaccagacttcatgagacgtccagacagaacattt
gacccattctctgagactcctgtggatggagtgattgcagccacctgctctgttcaggtt
atatctgggcagttcctctcagacaaaaaaatggggacgtatgttgaggttgatatgtat
ggattgccaacggacactataaggaaggagttccgtactcgcatggtaatgaacaacggt
ctgaacccggtttataatgaggaggcttttgtatttcgaaaggttatcttacctgacctc
gctgtgctgaggatagccgtgtatgatgacaacaataagctgataggccagaggatattg
ccattggatggtctccaggcaggatatcggcacatttcacttcggaatgaaggcaacaaa
cccctttccctgccaaccattttctgcaacattgttctgaaaacctacgtccctgatgga
tttggagatattgttgatgctttatcagatcctaagaaattcctgtctattactgagaag
agggcagaccagatgagagcaatggggatcgaaacaagtgatattgctgatgtgccaaac
gacaacacaaagaacgacaaaaaagggaaaaccaataatgccaaagccaatgtgactcct
caaacaagttcagagctaaggccgtctgctgcgtcctcctccgggatagcaatcgaagct
aagaaaggtatagatctcattcctcaagtgaaagtcgaagatttgaaacagatgaaggca
tatgtcaaacagctaaagaagcaacagaaagagataaactctatgaagaagaaacatgac
aaagagcaaagtgctgtgaggaaggtacactgcacacaagctgacaaattagtggcacaa
cttgataaggaaaagttgtctcttgagaagaacttagaaaaagcaatcaagaagaaagga
ggaaataactgtgttgaaatgaagaaagaaacagaaaataaaattcaggttttaacttca
gatcataaatccaaggtgaaagaaattgtggctcaacatacgaaagagtggtcagaactg
cttagcacacaagctgctgatgtgcaaaatctccaagatctacatttaagtcagcaatgt
gaactcctgaaaaagctgctgatcaccgtccaagagcaacagacacaacagctgaaactc
tcccatgaccgagagagcaaggagatgagggccaatcaagctaaaatttccatggagaac
agcaaagccataagccaggataaatctatcaaaaataaagctgagcgtgaaaggcgagtg
agggaattgaacagcagtaacacaaagaaattccttgaagaaaggaaaaggctggcaatg
aaacaatcaaaggaaatggaccagttgaagaaagcccagctggaacatttggagattctg
gagaagcagaacgagcagcttttgaaatcgtgtcatgctgtgtctcactcacaaggcaaa
ggaaatccagcagatggtcaaactggaagccgagatgggccgcaggccagcaacagttgt
gtaaagctgcaaaatgcaaactga

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