KEGG   Bufo bufo (common toad): 121003142
Entry
121003142         CDS       T07950                                 
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf04010  MAPK signaling pathway
bbuf04012  ErbB signaling pathway
bbuf04020  Calcium signaling pathway
bbuf04510  Focal adhesion
bbuf04520  Adherens junction
bbuf04530  Tight junction
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121003142 (ERBB2)
   04012 ErbB signaling pathway
    121003142 (ERBB2)
   04020 Calcium signaling pathway
    121003142 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121003142 (ERBB2)
   04520 Adherens junction
    121003142 (ERBB2)
   04530 Tight junction
    121003142 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbuf01001]
    121003142 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bbuf04147]
    121003142 (ERBB2)
   04090 CD molecules [BR:bbuf04090]
    121003142 (ERBB2)
Enzymes [BR:bbuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     121003142 (ERBB2)
Protein kinases [BR:bbuf01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   121003142 (ERBB2)
Exosome [BR:bbuf04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   121003142 (ERBB2)
CD molecules [BR:bbuf04090]
 Proteins
  121003142 (ERBB2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase GF_recep_IV Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like RIFIN TMEM154
Other DBs
NCBI-GeneID: 121003142
NCBI-ProteinID: XP_040290679
LinkDB
Position
6:complement(302218849..302321909)
AA seq 1251 aa
MDLQPWILGLCALLLQGGLCREVCTGTDMKLLHPYSHENHYQTLRTLYQDCQVIQGNLEI
TYLKESDDVSFLKDIKEVKGYVLIAHNLLSYIPLEKLRIVRGNQLFQDKYALAVLSNSQS
GGTAGLQELRMRSLTDILKGGVIIQNNTQLCFHESIKWEDVMIQSDRFHKDVVLQSGSRL
CPPCSSSCGSLSSGTAGSCWGEGEENCQILTSIICQSGCQRCKGKHSSDCCHEQCAAGCT
GPKNTDCLACLNFNNSGICEMHCPPLTIYNPLTFQTVINVNGRYTFGATCLVKCPYNYLA
TDVGSCTLLCPHETQEVLAGDMQKCEKCDKCTKVCYGLGMDFLKTTPFINSANIQNFRGC
KKIVGNLVFLPESFQRTSDNTTQLTVEDLEVFRTLEEIIGYIYIDMWSDELNSLQVFENL
RLIRGRLLYNGAYSLVIRNLSISSLGLRSLKEISSGIVLIEGNSNLCFLDTVPWTKIFRN
SRQTILQTGNEPQTTCEEEGHVCFHLCANAECWGSEASQCMQCDGLVRGLDCVDSCNVEE
GDPREIINGSQCIACHPECMPRNASNTCFGPLADQCVQCAHYKDGATCVNQCPSGKKVDS
YVPIWKYADKDGICQLCPVNCSHSCDKQDEKGCPIIVNNSQTYMIVAVVGSVLLLVTCAV
VLVLYIRRRKQLKKKHTLKRILQEHELVEPLTPSGAMPNQAQMRILKETELKKMKILGSG
AFGTVYKGIWIPDGENVKIQVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCRLLGIC
LTTTVQLVTQLMPYGCLLEYARENKDRIHSRDLLNWCVQIAKGMTYLEDIRLVHRDLAAR
NVLVRNPTHVKITDFGLARLLDVDETEYHADGGKVPIKWMALESILHRKFTHQSDVWSYG
VTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPVCTIDVYMIMVKCWMIDSEFRPKF
RELVTEFSRMARDPSRFVVIEDEELMSQSSPLTTQFYSDLLQDAAMEDLVDAEEYLVPHQ
GFFGCDESAVEHRSRMSSTQSQAETRIDQILMDETGHVEPLLSLTLSQKSDASESDDLSE
GDYVFDPPHPKENSLKRRYCKDPTLLGGKDTVDGRGLEIDGFIAPGSPTYPPEYVNQREP
SRSHSPVKTPRTSVSTLERQKGQLCWNGMIRDPRSPVPMSAVENPDYLPPPGMHLPNSFP
QAFDNPYYWNHELKAESEPNPTQNGFTTPTAENPEYLWLDEAMKRPRDVTA
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggacctgcagccatggatcctggggctctgtgccctgctcctgcaggggggtctctgc
agagaagtttgcactggaacggacatgaaactgcttcatccctacagccatgagaaccat
taccagactttacggaccctctaccaggattgtcaggttatccaaggaaacttagagatc
acctacctgaaggagagcgatgatgtgtcttttctgaaggacattaaggaagtgaagggc
tatgttttaatagcacataatctgctgagctatatccccttggagaaactgcgcattgtt
cgtggaaaccaactctttcaggataagtatgccctagcagtgctgtccaactcacagtct
ggaggaacagctggtctgcaggaactgcggatgaggagtctcacagatatcctaaaaggg
ggggtgatcatacagaataatacccaactttgctttcatgaaagcatcaaatgggaggac
gtcatgattcaaagcgaccgtttccataaagacgtggttctacagagtggaagccgtcta
tgtcctccttgctcaagcagctgcggatccttgtcctcaggaacagcgggatcatgctgg
ggagagggcgaggagaactgtcagattttgaccagcattatctgccagagcggctgccag
agatgtaaagggaaacattccagtgactgttgtcatgaacagtgcgcggccggatgtact
ggacctaagaacaccgactgtctggcatgtcttaatttcaacaacagcggcatttgtgag
atgcactgccctcctctcaccatatacaaccctctgacctttcagaccgtaattaatgtc
aacggaagatacacttttggagcaacctgtctcgtcaaatgtccttacaactacttagcc
actgacgttggttcctgcactctgctttgcccacatgaaactcaagaggtcctagcagga
gatatgcagaagtgtgaaaaatgtgacaagtgcaccaaagtttgctatggtcttggaatg
gacttcctgaagacgactccatttattaattctgccaatatccagaattttcgaggatgc
aaaaaaattgttgggaacctggtattccttcctgaatccttccagaggacttcagataac
accactcagctgactgtggaggacttggaagtcttcaggacccttgaggaaattataggc
tatatatacattgacatgtggtctgatgagctgaatagtcttcaagtgtttgagaacttg
cgtctcattcggggcaggctgctatataatggagcatattctctggtcatccgcaatctt
tccatctcgtctctcggattgcggtctttgaaagaaatcagcagtggaattgtactgata
gaggggaactctaacctctgcttcttggacacagtcccatggacaaaaatattcaggaat
tccagacagactattctgcagaccggcaatgagccacaaactacgtgtgaggaagagggc
catgtatgttttcatctttgtgccaatgcggagtgctggggcagtgaagcatcccagtgt
atgcagtgtgatggtttggtacgtgggcttgactgtgtggattcttgcaatgttgaggag
ggggatccaagagaaattatcaatggaagccaatgtatagcatgtcacccagagtgcatg
cctcggaatgcatcgaatacatgctttggcccattagcagatcagtgtgtgcaatgtgca
cattacaaagatggggccacttgtgttaatcagtgtccaagtgggaaaaaagttgactcc
tacgtgcccatttggaagtatgcagataaagatggcatctgccagctgtgtcctgttaac
tgctcccattcgtgtgataaacaagacgagaaggggtgccccatcattgtgaataatagt
caaacctatatgatagtggcagtggtaggcagcgtcttactcctggtcacatgtgcagtg
gtccttgtgttgtacatcagacgaaggaagcagttgaagaagaaacacaccttaaagcgc
atacttcaggaacatgagttggtggaacctttgactcccagtggagcaatgcctaaccag
gctcagatgaggatcctcaaggaaacagagttgaagaagatgaagattttggggtccggt
gcattcggcactgtgtataagggcatatggatcccagatggagagaatgtaaaaatccag
gtggcaatcaaggtattgcgagagaacacatctccaaaagcaaacaaggaaatcctggat
gaagcatatgtgatggcaggggtggctagtccgtacgtgtgccgtctgctggggatctgt
ctgaccaccacagtacaactggttactcagctcatgccatatggctgtctgctggaatat
gcacgagaaaataaggatcgtattcactcaagagatcttctcaactggtgtgtccaaatt
gccaaggggatgacatatctagaggacatccgcttagtgcacagggatctggctgcaagg
aatgttctggtgagaaacccaactcatgtaaagatcacagacttcggacttgcaagatta
ctggatgtggatgaaacagaatatcatgcagatggaggaaaggttcccattaaatggatg
gctttggaatctattctgcatcggaagttcacccatcagagtgatgtatggagctatgga
gttactgtgtgggagctaatgacctttggagctaaaccttatgatgggatccctgctcga
gagattccagatctattagagaaaggggaaagactccctcaacctcctgtatgcaccatt
gatgtgtatatgatcatggtgaagtgctggatgatagactcagagttccggcccaagttt
cgggagctagtcactgagttttcacgcatggctcgagatccaagtcgctttgtggtcatt
gaggatgaagagctcatgtcccagtccagccctttgactactcagttctacagcgattta
ttgcaagatgcagccatggaggatttggtggatgctgaggagtatctagttcctcaccag
ggattttttggatgtgatgagagtgcagtagaacatcgtagtcgaatgtcatctacacag
agtcaagcagagacacggatagaccagatcttaatggatgaaactggccatgtggaacca
cttttgtcgctaactttatcacaaaagtcagatgccagcgagtctgatgatctaagtgaa
ggagattatgtgtttgatccaccacatcccaaggaaaatagtcttaaacgcaggtattgt
aaggatcctacattgcttggaggaaaagacacagtggatggaagggggctggagatagat
ggcttcatagccccaggatcacctacatatcctccagaatacgtgaaccaaagagaacca
agcagaagtcactccccagtgaagacaccaagaacatccgtgtctactctggagcggcag
aagggacagctgtgctggaatggtatgataagggatccaaggagtccggtaccaatgagt
gctgtggaaaatccagactatcttcctcctccaggaatgcacttgccaaactctttccct
caagcctttgacaatccgtattactggaatcatgaactcaaagcagaaagtgaacctaac
cctacacagaacggatttaccacaccaactgcagaaaacccagaatatctgtggctagat
gaggctatgaaaaggccgcgggatgtgactgcataa

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