Bufo bufo (common toad): 121008640 Help Entry 121008640         CDS       T07950                                  Symbol PKD1 Name (RefSeq) polycystin-1 isoform X1   KO K04985   polycystin 1 Organism bbuf  Bufo bufo (common toad) Brite KEGG Orthology (KO) [BR:bbuf00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:bbuf03037]     121008640 (PKD1)    04812 Cytoskeleton proteins [BR:bbuf04812]     121008640 (PKD1)    04040 Ion channels [BR:bbuf04040]     121008640 (PKD1)    04091 Lectins [BR:bbuf04091]     121008640 (PKD1) Cilium and associated proteins [BR:bbuf03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    121008640 (PKD1) Cytoskeleton proteins [BR:bbuf04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     121008640 (PKD1) Ion channels [BR:bbuf04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    121008640 (PKD1) Lectins [BR:bbuf04091]  C-Type lectins   Others    121008640 (PKD1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 Polycystin_dom PKD_channel PLAT Lectin_C LRR_8 LRR_4 WSC Motif Other DBs NCBI-GeneID:  121008640 NCBI-ProteinID:  XP_040297241 LinkDB All DBs Position 7:complement(25087186..25188234) Genome browser AA seq 4338 aa AA seqDB search MHFGNAQAEALRRKDGASPPVLGLQLCPLFFLLAAGLLLGLGSGAATGWCQPCPGNCTCA NDTCLVNCSGAGLLDLEAVPASVTVLDLSDNRIETLDRRLFEQLQNLTDLDLSDNPWRCD CRMSWLPLWAAENGVRLKNPDSTLCDGPPVVSGEQLLNVSFSKTTCGGDLIFCPQNLSSA DESLLTFTPIPLSHPTNETCSAQCFANLYNFWTLDPKHGCFCGDTISTNMSLQCQEVCSS PSIFSSCNLTIVQEATSTKSFAILQSSQETYRLGDSVHLEVKAPIPVTPLLWDFGNQIYS TSDLNITHRYAQPGMYNVTVTLRLGSRDLIVHDELRVVGLPEKIQIICPTLVKTNDNVDV QVKVRGGTDLAVESTVTSESGEEVSPACPPGSVVCPLNNHCYQLVVEKAGWFDAQKVCQD LGNGDMAVVSSHELQKFLETRVTSGLEVWIGFNDTRSAESLPAGKRFDLESCQNWLPGEP EPSQADRCVRMGPNGVCNTDLCSSKHSYVCEYKPQALTLNAEYFVVGASVFDTNWPLQNL SRAENVSSPDEGVEVLMFPEFRFTQTVYLSALEFVTEDLEESAQMRFQVYTPSTVQGCLV KSTFSPISPLPINESFPECEEDLESSNYTNSTLPVESGCFPATESAISATESAISATSLP TQSSNSLPNFILMKEYFFIIPPGNATQYLASFEDVSIEVLPGSLIVVQHDAPPKKFLHCH STRSYHVVHQQSWMDCIPGDLLGGLLVNSTVDWPSKVDGGASCSIRVIGTTEENSLIFSH SPNGGLKNPGRYTVMAKFSNQLLEANHSCTFTVVSPVSGLEVAYPIPQEEIYYVPVNNPV LVLKLLTGSNATAFWVGTNQSWSFGQTCPPVISTRNTQCDAVGSDISYAEINLQGLGKEV VEVVILVENDISSENRTIQVKMEEPIRGLSISPYPQERVLVNTRVNNVASVDSGSDVVFK WTVDDRSSLTYCYTVFNVIYQTSAVYKLTLTASNHVSSASLTYNVTVEQMNPMRSLQVSG VPSIVTQNAFLELSATIILDSAVEATFRWTFGDGTQEDYHFKPPYNQSFPVPDPSVHMVL IENNITHTYQESGEYNLTLTVFNKYENSSQEVPLQVQGSLTNLTIITDVPVLVSEKSVVF QVIPEPSPFGVLYTWDFGDGTFYHNTSELALNHTYASSGTYNVSVHAVNDISEIWAVKAI HVYEEITGLVVSSDEPTERGLQTFINASVETGDNITWRFNMGDGHIFEGNEPMMNYTYCK DGNYTVNVTASNAVNSLSEFLQVRVYVLQVLKIEPSTCILENANVTLTAYVTGDYEHYTF NWTFGNNSSSITIYGIPSVEWDFSSSGIFPLSLILSSQVNKAYYYTNVCIEPEIVNVTLL PAQQNISLGKESHFQVIVFPAYQYRYVWDFGANGSRYNGGTEVQFLYRVPGVYQVMVSVF NNVSFHNGTALVDVQEPIGTIKIEHNGTQFLELDQIYLFSAVGIGTKVQYHWDFGDGNTA EGKTVTYIYNTTGSFTIILNGFNGVSSSRTHMNITVKTRIHGLNMNATRTVIPLNGSVTF SAFLKSGDDVRYSWILCDRCSPIFSNSTISYTFRSIGTFNVIVTAENELGSLQDSIVIYV LQTIEGLQIATGDLVNDCCFPTNKSLPLQATIKDGTNISYSWFILKNDSVIQSGTGKTYQ FMSVEPETYTIVLKAVNMLGNASVRINVVFVETLGQIHLLAFPNPAPLNTTVNISMSLSS GSGVMYTWYLEESVVWFTYESYILYSFQSPGPKEVLAIANNTLGSFNSTITIFVQEPVEG LSIMSLDHKGDYVPTGTVLYLTSSVQHGTNVSWIWSIPGGNIDGKVAIVPFEEAGFFTIS LNASNDVSWEIAYKNITVQDRIHGLKLHVSKIEVEPGELVTFNISLSAGSSVRYMLTING DFSIVLNSTTYTYEFTKIGGYPVTVVAQNEVSEERSTVMISVLEAIKNLKLVNCCEVAIP ARIEKNFRAAVSHGSLVAYNWLFDLQGHPATSLAGGNVTYTPVGAGGLTIHISASNALGS QNISKFIKVQELIVGLSLIPVNAFVNRSVTFNALVLPSPLDVKYEWSFGDNTPLLVRYSA SLNHTYQAPGDFKVKVNASNLISFWVSTITVTTRILECEEPEVQLQLPTQVIMRRSQKNY IEAEINLRGCISYQTKHLWEIYKAASCLHYRESDKVHLLNVDMSRPQLVVPKLALEIGDY CFVFSVSFGDTPLSKSSYANVTMLPSRLVPIIDGGSYRVWSSSRDLILDGKKSYDPNLEE EEQTPLSYKWSCTTLTKSLQSAPCNSEVTSDMGEMSIHKSKLEPDVEYTFFLTISKPDRH PESTNQTVLIKKGSIPIVSLKCVSCKAQSVYEVSASSYVYLEGSCSNCQDEARSGRWTAQ SFSNKTLILNTSTTTTGDRGLNLVLRQGVLKDGEGYTFTLHVRDPTMEEEGFASIDLLPN SPPSGGTCRIFPNGTIHALTDPVHFDCTGWRDTEDEVSLVFILRAKRCRGGHCDDFWVYK GSRSEHITFLPVGYQESNFMVEVSILVQDQQGATAVALNHTMGILMPVLPDRFQSFAEWL HNLTDSRLRGLLKQGDPQHVAEYSLALITVLNEYEKVMSKQEEASEQTLGKVRKNITDAL ISLKVNTVDDIRQIAAALAQCTVASKELACVSCQRTTLSKLEAMMSILQNETTQGMMTPT TIADNILNIMGDVIHLVNTKSFVHKGEKLCGALNNASVASKAYNLSSDLMRILMKSRVLN EEPLTLQGGEILARGKRSDPLNLLCYSNRTGCQFFIPQGFNSTFLDLTDIIQVMFQVDSN PYPYGFISNYTVSTKVASMEFQTSNGSQIPVESLDSEKAITVSVANNTGVGNITAGVANI ERRRSVKVDLEAESSNKNAGLHIQITYTVQDERYKDSEPEPYISVYLHETSHPNQYNFSD MKQISEDSLSGDDHKLYTFFIAPTDGNLTRRYYLNITNHYMWSPVDVTVGLYTSLCQYFD GNKMKWKTEGLVPLEDTRPDQAVCLTQHLTAFGASLFVPPHSVNFIYPPPPPGINYIVLL TCAVCFATYSVATIIVHKLDLLDVSKAGVIPFCGKAGSYKFEVLVKTGWGRGSGTSAHVG ISLYGVDSKSGHRHLDGENTFRRNSVDIFQIATEKSLGNVWKIRLWHDNKGLSPSWYVQH VIIKDLQRSKNYFFLVNDWLSVGQEESGRRVEKEIFAASETELKRFSRIFMAELQRGVSE KHVWLSMWERPPRSRFTRVQRATCCALLIFLFLCANAVWYGVVGDKNHGDRAVSESVPLS VDSVAVGLVTSVLVYPIYLIILYLFRRARSKTGVRPALTYFDQHSIEIDNYLDTVMESSF MGHTGNHGEAFSDQTKTEIPMADTKSFIQWNTNDGVLSWPDLLSDPSIMGNTIQKLERHR TSCNVGLDASCHPSEDDSVVLGLPQSLPRQFLASDGASSMSLPPELRRISRTDTDLLSDL SNPFGDKTETIMLDKLNEKGQTLSGSARDVTKSVRSNRTVITDAFQRHRQMLPSWCTRVA HVLSCFLLLSCFAVSVWIGVGFTSSVGLMWLISGIFSFLCSFFVLEPLKVLLEAVYFALV VKRLYPEEEDTLVECPLVEQVSERITKVRPPQGFALFQAREEARKVKLLHRMLKNLMVYT LFLLVVLLTNYGDASVNHRAYLLQRSVRQEMGSHKFMQIKRSDEFWAWASDVLLPFLKNS QRGSYSSLLGSARLRQIRLKNAVCDIHSLPGHGTCSEELDDINYDIGWTNTSDVSSWDWS YSPPDDTGAWYWGFLSFYDSSGYVQQLGGSLEENRAVLEDLQQDHWIDNLTRALFVEFSL YSPGVHLYSSVTLLLEFPLAGRSLPSAEIRAFPLLRLSSGAHLLLTMMVFLMMFVVYFVL AECLLIRKEGRFYFTHFWNYIQWLLTVLTVSTVVVYLSRGSLADQQWERYRKDKASFVNL HHVAFLGNTFNSLSASLLFLFTLKVAQQLRFIREWSVFGKTLSLSVKELCAAAGATLGLL LVYAQLGFLLFSSSWERFHSFGASVLSLFAVARGTITLKAPFPYSSYVHHLYFASYLVLE VWILMRFFGAMLINSYRQVRLDLFRPAYELQDYEMVELFLRRLRIWMGVSKVKEFRHKVR FEGMEPLPSRSSSDSKSLRGSTPSAASDTSSSSSFSTISSQLDTFSAVSTRERAEVDANI QRLLPVLETLLAQFDLVNHATEEVYQIERSLEDVQMRVAKKRRRQHGSTPTQRSPSHSQE TQVSQQNASLSGRRLKNSLPTSQSSSISQVLKESTSAGKMITMDKVVAEEPALIPMKLTQ NKRRKSMRAHNRVHPSVS NT seq 13017 nt NT seq  +upstreamnt  +downstreamnt atgcattttggaaatgcccaggctgaagccctaagaagaaaagatggcgcctccccccct gtgctgggactgcagctctgccccctcttcttccttcttgctgctgggctcttgctgggg ctcggatcgggggcagcaacgggatggtgccaaccatgcccgggtaactgtacctgtgcc aacgacacttgcctggtgaactgctctggtgcagggctgctggatctggaggctgtccct gccagtgtgacagtgctagatctttcagacaaccgcatcgagaccctggacagaagactg tttgagcagctacagaatctgacagacttggacctgagtgacaatccatggcgttgcgac tgccgtatgtcatggcttcctctatgggctgctgaaaatggggttagattaaagaatcct gactctaccctctgtgatgggcctccagtggtatctggcgagcagctgctcaatgtctcc ttctccaagaccacgtgtggaggtgaccttatcttttgtccacaaaatctgtcttctgcc gatgaatccttgttgacctttacgcccatccccctgtctcacccaacgaatgagacttgc agtgcacagtgttttgctaacctctacaacttctggaccctcgaccccaaacatggttgc ttttgcggtgacaccatctctaccaacatgtctcttcagtgtcaggaggtctgcagttct ccttccatcttttctagctgcaacctaaccattgtccaagaggccaccagcaccaagtca ttcgccatcttgcagagctcccaagaaacctataggctcggggattctgtgcatttagaa gtcaaggcgccaatccctgttactcctctcctctgggattttggaaatcagatctatagc accagtgatcttaacattacccataggtatgcccagcctgggatgtacaacgtgaccgtg actctccgtctagggagcagagacctcatcgttcatgatgaactgagagtggttgggttg cctgagaagatacagatcatttgcccaaccttggtgaaaactaatgacaatgtggatgtc caggtgaaggtgagaggtggaactgacctggcggtggagtctactgtaacatcagagagc ggtgaggaagtgtcccctgcctgtccacctggaagtgtggtgtgcccccttaataaccat tgttaccagttagtagtggaaaaagccggctggttcgatgcgcagaaggtctgccaggat ctcggaaatggagacatggccgttgtgagcagtcatgagttgcagaagtttctggagacc cgggttaccagtggtctggaggtgtggataggattcaatgacaccagaagtgccgaatcc ctcccagcagggaagcggtttgacctggagagctgccagaactggcttccaggggagccc gagccatcccaggcggatcgctgtgtgagaatgggacccaatggggtgtgcaacaccgac ctgtgcagctcgaaacacagctacgtgtgtgaatacaagccacaagctcttactctaaat gctgaatactttgtggtgggagcttcggtgtttgatacaaactggcccctgcagaacttg tcaagagcagagaatgtgtcctctcctgacgaaggggtggaggtgctgatgttccctgag ttcaggttcacacagaccgtctacttatcagctctagaatttgttactgaagatctggaa gagtctgcccagatgaggttccaagtatacaccccaagtacagtgcaaggttgcctggtt aaaagtaccttctctccaatttcccccctacccatcaacgagagtttcccagagtgtgag gaagatctggagtcttctaattacaccaacagcactttaccggtggagagcggctgcttc cctgccaccgaatctgccatctctgccaccgaatctgccatctctgccacctcattgcca acccagtccagtaacagtcttcctaacttcatcctgatgaaggagtatttcttcataata cctccaggaaatgcaactcagtatttggcatcttttgaggatgtgagcattgaggtgcta ccgggctccctcattgtggtccagcatgatgcaccaccgaaaaagtttctgcattgccac tctaccagatcttaccacgttgttcaccagcagagttggatggactgcattcctggggat ctcctcggaggattattagtcaacagcacagttgattggcccagtaaagtcgatggtgga gcatcttgctccataagagtcattggtaccactgaagaaaattctcttatttttagccat tcaccaaatggtggtctcaagaatcctggcagatacaccgtcatggcaaaatttagtaac cagttgcttgaggctaatcattcttgtaccttcactgtggtgtcaccagtttcaggcttg gaagtggcttacccaatccctcaagaggagatctactatgtccctgtcaataaccctgtt ttggtcctcaaactcctgacaggttctaatgcgacagccttttgggttggcaccaaccag agctggagctttgggcaaacatgtcctccagtgatttccacacgcaacactcagtgtgat gcagtaggaagtgacatttcttatgccgagatcaacctccagggtctcggcaaagaagtt gtggaagttgttatattagtggaaaatgacataagctcagaaaacagaacaattcaagta aaaatggaggaacccatcagaggactgagcatcagcccatacccacaggagagagttctg gtcaacacccgggtgaacaatgtggcttctgtggattctggatctgacgtggtgttcaaa tggacagtggacgatcgctcgtctcttacctactgctacaccgtcttcaatgtcatctac cagacatcagctgtgtacaagctaacgctgaccgcctccaaccacgtcagcagtgcctcc ttaacctacaatgtcacagtagagcagatgaaccccatgcgaagtcttcaagtcagtgga gtcccaagcattgtgacccagaatgcatttctagagctctctgctaccatcatacttgac tctgcagttgaggccacattcaggtggacgtttggggatggcacacaagaagattatcat ttcaagcctccatataaccagtcgttccctgttcctgacccgtctgttcatatggtgctt atagagaataacatcacccacacctatcaggaatccggagaatacaatttgacattgacc gtcttcaacaagtatgaaaactcgtctcaggaggttcccctgcaggttcaaggatccttg accaacttaaccattattactgacgttccagtcttggtcagtgagaaatctgtcgttttt caagtaatccctgaaccctcaccattcggtgtcctctacacctgggactttggtgatggc accttctaccataataccagtgagctagcgttgaatcacacgtatgccagctctgggacg tacaacgtcagtgtccatgctgtcaacgacatcagtgagatatgggcagtgaaggccatc catgtttatgaggagataaccggtttggttgtgtcatctgatgaaccaactgagaggggc ttacagacctttatcaatgcttcggtggaaactggggacaatatcacgtggaggttcaac atgggcgatgggcacatattcgagggtaatgagcctatgatgaactatacatattgcaaa gatggaaattacacggttaatgtaactgctagcaatgcggtcaactctttgtcggagttc cttcaagtccgcgtgtatgtcctacaggtacttaaaatagaaccctctacttgcatcctc gaaaatgcgaatgtgacactcactgcgtatgttacaggggattatgaacactataccttt aactggacctttggcaataattcctcaagtatcaccatttatgggatcccatcagtagag tgggacttctcgtcaagtggaatattcccgctttcccttatactctccagccaggtgaac aaagcttattattacaccaatgtttgcatcgagcctgaaatcgtcaacgtcaccttattg ccggcacaacagaatataagtctaggcaaagaaagtcatttccaagttattgtcttccct gcctaccagtacagatatgtatgggactttggtgcaaatggttctagatataatggtggg acggaggtccaattcttgtacagagttcctggtgtgtatcaagtaatggtgtctgtgttc aacaacgtctctttccacaatggtactgcgttggtagatgtccaagaacccatcgggact atcaaaattgaacacaatgggacacagtttttggaactagatcagatctacttattttcg gccgtaggaattggaaccaaagttcaatatcactgggattttggagatgggaacacagct gaaggaaagacagtgacttatatttacaacaccacagggagctttaccatcatcctgaat ggtttcaatggtgtaagtagcagtagaacccatatgaacataacagtcaagactcgaata catggactaaacatgaacgccaccaggactgtgattcctctgaacggttccgtgaccttc tctgccttcctcaagtcaggagatgatgtccgatattcatggatactatgtgatcgttgc tctccaatatttagtaattccacaatttcgtacactttccgctctattggaacatttaac gtcatcgtgacggctgagaatgaactcggttccctccaggatagtattgttatatatgta ttacagaccattgaaggacttcaaattgcaacaggtgatttggtcaatgattgctgtttc ccgaccaacaagagcctacctctacaggccaccatcaaagatgggaccaatatttcatac agttggtttatcttaaagaatgacagtgtaattcagagtgggacaggcaaaacttatcag ttcatgagtgtggaacctgaaacttataccattgttctcaaggcggtcaatatgttggga aatgcaagcgtcaggatcaacgtggtgtttgtggaaacccttggccaaattcatctcttg gcgttccctaatccagctcctctcaacacaacagtcaacattagtatgagtttgagcagt gggtctggggtgatgtacacttggtatctggaggaaagtgtggtctggttcacttatgaa tcctacatattgtatagttttcaaagccctggtccaaaggaggtacttgccattgccaac aacacattaggctctttcaactcaacaatcacgatctttgtgcaagagccagttgagggt ttatccataatgagcttggaccataaaggagattatgtgcccacggggactgtcttgtac ctcaccagcagtgttcagcatggtacaaatgtgtcatggatctggagcattcctggtggg aacatcgatggaaaagtggccattgttccctttgaggaagctgggttcttcacaattagc ctcaatgcctcaaatgatgtgagttgggaaattgcatacaaaaacatcacagtccaagac agaatacatggtctgaaactgcacgtgagcaagatagaggtggaacctggggagttggtc accttcaacatcagtttgtctgctggttcctctgtccgctatatgctgaccataaatgga gacttctccattgttcttaacagtaccacttacacatacgagtttaccaaaattggtggc tatcctgtgactgtggtggcacaaaacgaagtgagtgaagaacggtcaacggtcatgata tccgtgcttgaagccataaagaacttgaaacttgtaaattgttgtgaagttgccatacca gctaggatcgagaaaaacttcagagcagcagtcagtcatggctctttggttgcctacaat tggctttttgatctgcagggtcaccctgccaccagtttagcaggaggaaatgtgacttac accccagtaggtgctggaggcctcaccatacacatcagtgcatcgaatgctctgggaagt cagaacatctcgaagtttataaaagtccaagaactgattgtaggactcagcttgattcca gtcaatgcattcgtaaacagaagtgtaacatttaatgccctcgtgcttccaagccctctg gatgttaaatatgaatggtcttttggagataatactcctcttttagtaagatactcagca tctctcaaccatacttaccaggcacctggagactttaaggtgaaggtcaatgcctctaat ctaatcagtttttgggtctctacaataactgtgaccacacggatacttgagtgcgaggaa ccagaagtacagctacagctgcctactcaagtgattatgagaagatcccagaagaattat attgaggctgagatcaatctccgtggatgtatcagctaccaaaccaaacacctatgggag atttacaaagcagccagctgccttcactaccgcgagtctgacaaggtccaccttctgaat gttgatatgagccgacctcagctggtagtgcctaagctagctctcgagattggagactat tgctttgtgttctcagtgtcctttggagacacaccattgtctaaaagcagttatgccaat gttacgatgttgccgagcagactggtgcctatcattgacggaggatcctatagagtttgg tcaagtagtcgggatttaatattggatgggaagaagtcttatgacccaaatcttgaggaa gaagagcagacacccctctcatataagtggtcatgtacaacgctgacaaagagtttacag agtgctccatgtaattcagaagtcacttcagatatgggtgagatgtccatacacaagtca aagctggaacctgatgtggagtacacctttttcctgactatcagtaaacccgatagacat cccgagtccaccaaccaaacggtattaattaaaaaaggcagcattcccatcgtgtctctg aagtgtgtgtcctgcaaggcgcagtctgtgtatgaagtgagcgccagctcctatgtttac ctggaaggatcctgcagtaactgtcaggatgaggcgcggtctgggaggtggacagctcag agcttcagcaacaagaccttgatcctcaataccagcaccacaaccacaggagaccgaggg ctgaacctggttctcagacagggagtgttaaaagacggggaggggtacacgttcaccctt catgtcagagatcccaccatggaggaagaaggattcgcatccatagatctgctccccaat agtccaccttctgggggaacctgtagaatctttcctaatgggaccatccatgcgctgacc gacccagtccactttgattgtacaggatggagagatacagaagatgaggtttctctagtc ttcatcttgagggctaagcgctgccgcggcgggcactgcgatgacttctgggtctacaag ggcagccggtcagagcacatcaccttcctgcctgtcggctaccaggagtccaacttcatg gtggaagtttctatacttgtgcaggaccagcagggggcaacagcggtggccttaaaccac accatgggtattttgatgccagtcctcccagatcgatttcagagcttcgcagaatggttg cacaacctcacagattctcgcttgcggggtttattgaagcagggagacccccagcatgtt gctgagtattccttggctctcatcaccgttctgaatgagtatgaaaaagtcatgagcaaa caggaagaggcaagtgagcagacccttgggaaagtgcgcaaaaatataaccgatgccctc atatctctaaaagttaacacggtggatgatatacggcagatcgcagcagcgcttgcgcag tgtacggtggccagtaaggagttggcatgtgtgtcttgtcagcggacaacgctcagcaag ctggaagccatgatgtccatcttgcagaatgaaacgacacaaggaatgatgaccccgacc accattgctgacaacatcttgaatatcatgggtgatgttatccatctggtaaacaccaag tccttcgtccacaaaggagagaagctatgtggtgccctcaacaatgcctctgttgcctcc aaagcttacaatctttcttctgacctcatgagaattttgatgaagtccagggtcctgaat gaggagcctttgaccctccagggtggggagatcctggcccggggcaaacgctcggatcct ctcaacctgctctgctacagtaacaggacgggctgccagttcttcattccacaaggattt aacagcaccttcctggacctcaccgacatcatccaggtcatgttccaagtggactctaat ccctatccttacggcttcatcagcaactacaccgtgtccaccaaggtggcatctatggag ttccagactagtaatggcagccagatcccggtggagagcttggattcggaaaaggccatc acggttagcgttgccaataacactggtgtcgggaatatcacagctggcgtggccaacatt gagagacggcgctcggtgaaagtggacctcgaagcagagagcagtaataagaacgcagga cttcatatacagattacttacacggtgcaggatgagagatacaaagacagtgaacctgag ccgtacatctctgtctatctacatgagaccagtcatccgaaccagtataacttcagcgac atgaagcagatcagcgaggactctctgtcaggagatgaccacaagctgtacacgttcttc attgcccccacagatggaaacctgaccagacgctactacctaaacatcacgaaccattac atgtggtcgcctgtggacgtgacggtgggcctgtatacctccctgtgtcagtactttgat ggtaacaagatgaaatggaagacagagggccttgtaccgctggaggacaccaggccagac caggctgtgtgtctaacccaacatctcacagcatttggggccagcctcttcgtcccacct cactctgtcaactttatctacccgccgcctcctcctggtattaactacattgtgctgctc acgtgtgccgtctgctttgctacctactctgtggccaccattattgtccataaattggac ttgctggatgtcagtaaggctggagttattccgttttgtgggaaagctggatcttataaa tttgaggttctggtgaagacaggatggggccgagggtctggtaccagcgctcatgttggc atcagtctgtatggagtggacagtaaaagtggccacaggcatctagacggggagaatacc ttccgcaggaacagcgtggacatcttccagatagcaacagagaagagtttgggaaatgtt tggaaaatccgtctgtggcatgataataaaggactcagcccttcttggtacgtgcagcac gtcatcatcaaggatctgcagcgcagtaagaattacttcttcctggtgaatgactggctg tctgtggggcaggaggagagcggccgtcgggtggagaaggaaatctttgcagccagtgaa acagaactgaagcgattctcccgcatcttcatggctgaactccagcgaggagtctccgag aaacatgtctggctgtctatgtgggaacgaccaccccgcagccgcttcacccgcgtccag agagccacctgctgcgctctactcatattcctcttcctgtgcgctaatgctgtgtggtac ggcgtggtaggagataagaatcatggggatagagcggtgtcggagtctgttcccctcagc gtggactcggtggctgtgggactggtgactagtgtcttggtgtatcccatctacctgatt attctctacctgttcagacgagcccgcagcaagaccggcgtccggccggccctcacctac tttgaccagcactctatagaaattgacaactacttggacacagtgatggagagctccttc atggggcacacggggaaccatggagaggctttctctgaccaaaccaaaacagaaattccc atggcagacacaaagagcttcatccagtggaataccaatgacggcgtgctcagctggccc gacctcctcagtgatccttccatcatgggcaacaccattcaaaagctggagaggcaccga accagctgtaacgttggcttagatgccagctgccaccccagcgaggatgatagcgtggtg ttagggctaccacagtctctaccacgtcagttcttagcatcagatggagccagcagcatg tcccttccaccagaacttagaaggatctctcggaccgacactgatctgctatcggactta tcgaacccgtttggagataagacagaaaccatcatgttggataaattgaatgaaaaaggg cagactttatctggatctgccagggatgtgaccaaatcggtcaggtccaaccggacagtc atcacagatgctttccagagacacagacagatgctgccatcttggtgcacacgtgtggct catgtgctcagctgcttcctcctcctttcctgttttgctgtttcggtgtggattggggtg ggcttcacctccagcgttggtctcatgtggctcatctctggaatattcagcttcctctgc tcgttctttgttttggagcccttaaaggttctcctggaggccgtatactttgcactggtg gtgaagcgactgtacccagaagaagaggatacattagtagaatgccccctggtggagcag gtctctgagagaatcaccaaggtgcgaccaccacaaggatttgccttgttccaggccaga gaggaagcacggaaggtcaaacttctgcataggatgctcaagaacctgatggtttacacg ctcttcttactggtcgtcctcctgaccaactatggtgatgcctccgtgaaccaccgggcg tatctgctgcagcgctcagtgcgacaagagatgggaagccacaaattcatgcagattaag aggtcggatgagttctgggcctgggcttctgatgtgctgctgccattcctgaagaacagt cagcgggggagctacagcagcttgttggggtctgctcgcttacgccagattcggttaaag aacgcagtgtgtgacatccactcattgcccggccatgggacctgttcagaagagcttgat gacatcaactatgacattggttggaccaatacttctgacgtctcctcctgggattggtca tattctccaccagatgatactggggcatggtattggggtttcctctctttctacgacagt tccggttacgttcagcagctgggtggcagcttggaggagaaccgagccgtcttagaggac ctccagcaagaccactggattgacaacctcacgagggcgctatttgtggagttctctctc tatagccctggggtccacctttactcctcagtgacgctgctgctggaattcccactggct ggtagatcgttgccatcggctgaaataagagctttccctttactgcgcctgagcagtggt gctcacctactccttactatgatggtcttcctaatgatgtttgtggtgtactttgtgctc gccgagtgcctattgattaggaaggaggggcgcttctattttacccacttctggaattac atccagtggttactgacggtcttgacggtgagcaccgtggtggtatacctgagtcgaggc agcctggccgaccagcagtgggaaagataccggaaggacaaagcctcgtttgtcaacctg caccatgtggccttcttgggtaacaccttcaacagtctctctgcctccctgctcttcctc tttacactgaaggtcgcgcagcagctgcgattcatcagagagtggtccgtatttgggaag acactgagtttgtcagtgaaagagctatgtgctgcagctggggccacactaggtttgctg ctggtgtacgctcagcttggctttttgcttttctcatcctcctgggagagatttcacagc tttggggcgagcgtcctctctctgttcgctgtggctcgtggcactattactctgaaagcc cctttcccgtattcctcctatgttcaccatctttacttcgcaagctacctggtgctggaa gtatggatcctgatgcgattctttggggccatgttgatcaatagttaccgacaggtgcgg ctggatttgttccgaccagcatacgagctgcaggactatgagatggtggagctctttctt agaaggcttaggatctggatgggtgtcagcaaagtgaaagagttccgtcacaaggtgcgt tttgaagggatggagccacttccttcacgttcctccagtgattccaagtctcttcgaggt tccacccctagtgcggcttctgatacatcctcttcctcctccttctccaccatctccagt cagctagatacattcagcgctgtgagcaccagggagagagcagaagtcgatgccaacatc caaagattgctccctgtgctggagactcttctggcacagtttgatctggtcaaccacgct acagaagaagtgtatcaaatagagcgcagccttgaagatgtacaaatgagagtagccaag aagaggagaaggcagcatgggagcactccgactcagaggtcacccagtcattcccaagaa actcaagtgtcccagcagaacgcttcattaagtggaagaaggttgaagaattctctgcct acttctcagtcttccagtatttctcaggtattaaaagagagcacttcagcaggcaaaatg atcactatggacaaggtggtggcagaagaaccagcactcatccccatgaagttaactcag aacaaacggaggaagtcaatgcgggcacacaacagagtccaccccagtgtcagttag

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