Buteo buteo (common buzzard): 142032154 Help Entry 142032154         CDS       T11399                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism bbut  Buteo buteo (common buzzard) Pathway bbut04020   Calcium signaling pathway bbut04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:bbut00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     142032154 (RYR3)    04020 Calcium signaling pathway     142032154 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:bbut04040]     142032154 (RYR3) Ion channels [BR:bbut04040]  Voltage-gated cation channels   Ryanodine receptor    142032154 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  142032154 NCBI-ProteinID:  XP_074886498 LinkDB All DBs Position 6:35830167..36075342 Genome browser AA seq 4873 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNASEGAAQGGGHRTLLYGHAILLRHSFSEMYL TCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRLFHGHDECLTIPSTD QNDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLALNED EGLVMLDREKSDTTSTAFCFRVSKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVTS ALWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQ FISGNNRTLSPSALPIEEMAQTLQDLITYFQLPEEDLGHEDKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNDYNSAAHFAGIAREEHGTAWKEILNLLYKLLAALIRGNRNNCTQFSS NLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDV LCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFFPVVS LSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGT TQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKR HHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMS NGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYALLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEIADQTVEKVSIDKIRFFRVERSY AVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGR SWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLAQIGR MNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRID GTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFSFGMGVENASSDVFQKRKHS QEIAVLCTTYFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRV HESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGSCYQVE PNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPV LWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFH YHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIHLEHA KQAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEE HQTSSPDIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMGVF DDDDVKQVLILIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIKETKAPAKGLLQ TRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADCYVSKLQYNQKYRYNELMQALNMSA ALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEE EEEDSSLTGKLRSLIYKIKGPPKAEKAEPKEEEEKSPTTLKELISQTMVRWSQEDQIQDP ELVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEE ELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQQIVFPKMVASCCR FLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALE EPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENAS VVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQAYKREGDEEEEEEE IVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPL KLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASA SLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRS LTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKY YCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIAG ALPPDYLDTRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAF DKTNSGWKYGVSLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERAKE GGEAIIHQRENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKK KKMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDAS SMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQY FTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLH ILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNI NYTTVALLPILTSIFEHISQHQFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPA LGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGL IKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESLPQSAGPCCTMITSEHLS IILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIV MEEEQLRADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDE LFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKSGGQDQERKKSKR RGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDDEVKEHLRNNLH LQEKSDDPAVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQVEQPLRSKKAVW HKLLSKQRKRAVVACFRMAPLYNLPRHKISNFFLSTFQRVWLEKVHEKTQYDRLILKLTT PPKKEEEEEEETEKKQPDPLHQIILYFSRSALTERSKLEDDPLYIAYSAMMAKSCQEEEE EEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHPGPMVVETLKLGIA ILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEG TLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYL LRLQESISDFYWYYSGKDFIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHS RLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQ MVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQY VQSEIEFLLSCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSL LEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVN EGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEEEEEAEPCYVVDIGDDEEEEKS LESASAFAMACVAVKKNVANFFKMATVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGM FQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVMEAEKAEG AEHGVRAELVQFVKGEKGETDIISDIFGIHTKKEGGSKHGHDAGLGDIAEILGADTQSSL ENTVRKKKGLQISEIAKEAEAERKAEAEKADMEDGEKQDIAKEVQSEQLEEGKMKKKKRR HGQKIEKPEAVMANFFKALEIYQIKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEE PLDEVEEDSNLWNSFDEEDEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYC LKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRK VINKYGDLYGAERIAELLGLDKSALDFSPVEESEPEEASLVSWLSSIDTKYHVWKLGVVF TDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLL AVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDP AGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIG NDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPA GDCFRKQYEDQLG NT seq 14622 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagtattcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatctgtaatttcgtcctcgaacagtccctatctgtcagagctcttcaa gaaatgctggccaacacaggggataatgctagtgaaggtgcagctcaagggggtggtcac agaaccctgctgtatggccatgctatactacttcgacattcgtttagtgaaatgtatttg acatgtttaacatcatcaagatcccagacggataaacttgcatttgatgtgggactacga gaaaatgcagcaggtgaggcatgctggtggacaatacaccctgcttctaaacagaggtca gaaggagaaaaagttcgaatcggtgatgatcttatcctggtcagtgtgtcctctgaaaga tacctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacg ctatggaatgtacatcctacatgctcaggaagcaatattacagaaggatatcttcttggt gggcatgtagtacgtttgttccatggccatgatgagtgtttgacaattccatctacagat cagaatgattcacagcagaagaaagtactttatgaaaccggaggagctggtgttcgagca aggtctttgtggagagtagaaccccttcgaataagctggagtggaagtaacatcagatgg ggacagcctttccgtcttcggcatattacaacaggaaagtacttggctctgaatgaagat gaaggacttgtaatgttagacagagaaaagtcagacacaacatctactgccttttgtttt agagtatcaaaggagctaaaagaaaagcaggattctagtcttaaacgtgacattgatgga atgggagtcccagaaataaagtacggtgattcaatctgttttgtccaacatgtgaccagt gccttatggttgacttacaaagcacaagatgctaaatcagcacgtttaggtcccttgaaa agaaaggttatattacaccaagaaggccatatggatgatggtctaaccttacaaagatgt cagcatgaggaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccag tttataagtggaaacaacagaacactatcaccctctgccctgcctattgaggagatggct cagactctgcaagacctgattacttacttccagcttcccgaagaagacctgggacatgaa gataagcaaagcaagcttcggtcactcaaaaacagacaaaatctattcaaggaagaggga atgctggcactagttttgaattgcattgatcgcttaaatgactacaacagcgcagctcat tttgcaggaattgcaagagaagaacatggtacagcatggaaagaaattttgaatctcctt tacaaattgttagctgctctcattcgtggcaacagaaacaattgtactcagttttccagt aacctggattggctaataagtaaattggacagattagaatcttcctcaggtattttggaa gtattgcactgcatcttgattgaaagcccagaagctttaaatattatagctgaggagcac atcaaatccattatttcattattggataaacatggtcgcaattacaaggttctcgatgtg ctttgctctctctgtgtctgtaatggagttgcagttcgtgccaatcaaaatttgatctgt gacaatctactgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgaca agcataagaccaaacatatttttgggtgttgctgagggctctgcccaatacaagaagtgg tactttgagttaataattgatcaggttgatccattcttgacggcagaacccacccattta cgagttggatgggcctctacttcaggttatgccccctatcctggaggtggagaaggatgg ggaggcaatggtgttggtgatgacctgtactcgtatggttttgatggccttcatctgtgg tctggtcgagttcccagagctgtggcatctgtcaatcagcatttattagcatctgatgac gtggttagctgctgcttggatttaggtgtacccagcatttcattccgcattaatggacaa cctgtacagggaatgtttgagaacttcagtacagaagggtttttcttccctgttgtaagt ttatcagcaggtgtaaaagttcgtttcttactgggtggacgtcacggagagtttaaattt ctgcctcctgctggctatgctccctgttacgaagcattgcttccaaaagagaagatgaaa ctggaaccagtgaaggaatataagagagattctgatggagtgagggatttgctgggtaca acacaattcctctcccaagcctcctttatcccttgtccgatagacactagtcagattgct cttccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgg ggaatgaataaaatagaactgggctggacatatggcaagatacgggatgataataaaagg catcatccttgtcttgtggaattctcaaaactacctgagacagagaagaattacaatcta caaatgtcaactgaaaccctcaaaacccttttggcccttggatgtcacattgttcatgct catccagcagctgaggaagatcttaaaaaagtcaaacttcctaaaaattacatgatgtca aatggatataaacctgccccccttgatctttctgaagtgaagttgttaccttctcaagaa tttctagttgacaaactagcagaaaatgcacataatgtgtgggcaaaagacagaataaag caaggatggacctatggcattcagcaggatcttaagaacaaacgtaatcctcggctagtg ccatatgcattattagatgaacgtaccaaaaaatcaaacagagatagcctccgtgaagct gttagaacatttgcaggctatggttatagtattgagccacctgaccaagagatagctgac caaacagtggaaaaagtcagcatcgacaagatacgatttttcagagtagaacggtcttat gcagtgaaatctggaaagtggtactttgaatttgaagctgtgacaggtggagatatgcgt gttggttgggccaggccaggctgtcgacctgacatagaattgggagctgatgaccaagca tttgtatttgaaggaagcaaaggccagcgttggcatcaaggcagtggattctttggacga agctggcaaccaggagatgtggttggttgtatgataaacttggatgacaaatcaattatc tttactctgaatggagagttgcttataacaagtaaaggttcagaacttgcatttgctgac tttggaatagaaagtggttttgttccaatttgtgcactgggtctagctcagattggtcgt atgaaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaa ggttttgaaccttttgctgtcaacatgaaccgagatgttgctatgtggtttagtaaacgc ttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagatatggagaattgat ggaaccattgagagtccacctcggttaaaagttactcacaaaacatttggcacacagaac agcaattcagacatgatatattgtcgcttgagtatgcccattgaattccgctcatcattc agctttggcatgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaaacacagc caagaaattgctgttctttgtactacgtatttttattcactacggatatttgctggccaa gacccatcttctgtctgggttggctgggtaacaccagactatcatttttacagtgagaat tttgacctaaataaaaattgtacagtgacagttactttaggtgatgagagaggcagggtt catgaaagtgtgaagcgcagcaattgctatatggtttggggaggagatgtaattgctaat tcccagagatcaggtcgcagtaatgttgatttagaaattggatgctttgttgacctggct actggaatgttgtcattcacggccaatggaaaagagcttggcagttgttatcaggttgaa ccaaacacaaagctttttccagcaacttttgtacagcctacgagcactaacttggttcaa ttcgaacttggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgaa gaaagaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtt ttatggagcaggatgccaaacagcttcctaaaagtagaaactgagcgtgtcagtgaacgt catggctgggttgtgcagtgtttggaacccctgcagatgatggcacttcatatcccagaa gaaaacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagtttcac taccacactttaaaactctatagctcagttagtgctctaggtaacactagagttgcttat gcactttgtagccatgtggacatatctcagctattttatacaatagataatcaatattta cctggacttctacgttctggattctatgacttgctcattagtattcatttggagcacgcc aagcaagccaagctcatgatgaacaatgaatttatcattccagttacagatgaaactcga actattaaattatatcctgatgaaacaaagaagcatggtttacctggagtagggcttagt acttgtctaaaaccaggctttaatttttctactccatgctttatcgtgaccagtgaagaa catcagacatccagcccagatataccccttgatacacttaaatccaaggccataagtatg ctaacagaggcagtacagtgtagtggtactcatatacgagaccctgttggaggacaggtt gcattccagtttgttcctgttcttaaactgatagcaacattgctcataatgggggttttt gatgatgatgatgtgaagcaggtgttaatcctcattgatcccaacgtgtttggagatcac aaggaagaaacagaagagaggacagagaaggaagaagttacacaagttgaagaaaaagct gtagaagctggcgagaaagcaataaaagaaacaaaagctcctgcaaagggcttattacag acaagattaccagaatctgttaagcttcagatgtgtcatttactcaattatttctgtgac tgtgagctacaacatagagtggaagcaattgtatcatttgcagactgttatgtatcaaaa ctgcaatataatcagaaatacaggtacaatgaactcatgcaagccttgaacatgtctgct gctttgactgccaaaaagactaaagagtttcggtctcctcctcaagaacagattaatatg ttgctgaattttcaactgggagaggattgtccttgtccagaggagattcgggatgagtta tatgaatttcatgatgatcttctaattcactgtggtattccactggaagaggaggaagag gaagaggaagattcctccttgactggcaaactccgttcattaatatacaaaatcaaaggt ccaccaaaagcagaaaaagcagaacctaaggaggaagaagagaaatctcctactacgctg aaagaactcatatcccagactatggtgcggtggtcccaggaagatcagattcaagatcca gaattagttcggattatgtacaccctccttcgtaggcagtatgacagcattggtgagcta ctgcaagctctgaggaaagcgtacactattagtgctgcttctgtgaaggataccattaat ctgcttgcagcactgggccagattcgctcacttctcagtgtcaggatgggaaaagaggag gaattgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcaacat cctaacttaatgagagtcttgggcatgcatgagactgttatggatgtgatggtgaatgtg cttggaggagataaatctcagcagatcgtttttcctaagatggtggcaagctgttgtcga ttcctgtgctacttctgtcgaattagtcgtcaaaaccaaaaggccatgtttgagcatctt agttacttgctggaaaacagcagcgttggtctggcgtttccttcaatgagaggttcaaca ccactagatgttgcagcagcctctgtaatggacaacaatgagcttgcactagcattggag gagccagatctcgataaggttgttacctacctggcgggttgtggcctgcagagttgtccg gtattgctggctaaaggatatccagacattggatggaatccgatagagggtgaacgttac ctgtctttcttaagatttgcagtttttgttaacagtgaaagtgttgaggaaaatgcaagt gttgttgtcaagctccttattcgaaggccagagtgctttggaccagaccttaggggagaa ggaggaaatggtttgctggcagctatgcaggaagctatcaggatctcagagaatcctact cgtgaccttccctcccaggcatataaaagagaaggtgatgaggaggaggaggaggaggag attgtgcacatgggcaatgcaatcatgtcattttactcagctctcatagatttacttgga cgctgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatcagg tcaatccttcgatctctagtgccaactgaagatttggttgggattataagtataccacta aagctgtcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaatttc tgtcctgatcataaagcacccatggtactcttcttggaccgtgtctatggtattaaggac caaagcttcctccttcacctactggaagttggatttttaccagatttaagagcctctgcc tctttggatacagtttctctaagtaccacagaggcagctctcgcactaaatagatatatt tgctcagctgtgtttccattactcaaaagatgtgctcccctcttttctggaacagagcat cacgcctctctggttgactccatgcttcacacaatatatagattatcgaagggacgttcc cttacaaaagcacaaagagacaccattgaagaatgcctgcttgctatttgccaccactta cgtccctctatgctacaacagctgttgagaaggctagtttttgatgtgcccctacttaat gaatactgtaaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaatat tattgtctgccttcaggaatgggaagctatggaattgcagcagaagaagaattacattta actgaaaaacttttctggggaatatttgattccttgtctcataagttcctatctctcctg cagaagtatgatccagagctctttcgaatggctttgccttgtctaagtgctatagctggt gccttgccccctgattatttagatacacgaattaggtcaactttggaaaagcagacttca gtggatccagaaggaaattttgatcccaaacctgtcagcacagcaaaccttgtacttcct gaaaagttggagtatattgtcagcaagtatgctgaacattcccatgataaatgggccttt gataagactaatagtggatggaaatacggtgtttcactggatgaaaatatgaagactcac ccattaataagacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttggcct gcaagagaatcactgaaaaccatgttggccatgggatggagcctagaaagggccaaggaa ggaggagaagcaataatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtct agccagggaaatgggtatagcccagcaccacttgatctctctaatgtagtgctctctagg gagcttcagggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaag aagaaaatggagttggaaagcaaaggtggaggtagtcatcctttattggtaccttacgat acattgacagccaaggagaaatcacgggatcgtgaaaaggcacaagagctgtttaaattc cttcaagtcaatggtataatcatatctcggggtctgaatgacatggacttagatgcttca tccatggaaaagaggtttgcctttaagtttctgaagaaaattttaaaatacgttgattct gctcaagagtttattgcacatttggaagccattgtaaccagtggaaaaactgaaaaatcg ccacatgaccaagaaataaaattctttgccaaagttcttttaccattagttgatcagtac tttacaaatcactgcctctacttcctgtcttctccaacaaaaacactcagtagcagtgga tatgcatcaaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctctt gttagacataggatctcactttttggtagcgattcagctacaatggtgaactgcctgcac atcttagctcagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaa gctggattgcgtgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaaaat cttaaacttggaaaatttacccattcacgaacacaaatcaagggtgtttcacagaatatc aattatactacagtagcattgttaccgatcttgacatcaatttttgaacatatttcacaa catcagtttggaattgatttacttttgggtgatgtacaagtttcatgttacagaattctt tgtagcctctattcccttgggactgggaagaacatctatgttgaaaggcagcgtcccgca cttggtgagtgcttagcatctcttgcagcagccattccagtagcattccttgaaccttct ctcaaccattacaacccattgtctgtcttcaacacaaaaagtgcaagagaaagagcaatt ttaggtatgcctgatacagtagaagagatgtgtccagagatccctcagttggatggacta ataaaggaaattaatgatttagcagagtctggagcaaggtataccgaaatgcctcatgtg attgaggttatcttacccatgctgtgcaactatttgtcctactggtgggaaagagggtct gagagtcttcctcaaagtgctgggccttgctgtacaatgataacatctgagcatctgagc atcattcttggaaacattctgaaaatcattaacaacaatctgggaatagatgaagcatct tggatgaaaagaattgcagtttatgctcaacccatcatcagcaaagccaggcctgatctg ctcaaaactcactttattccaacactggagaaattgaagaagaaagctataaagattgtg atggaagaggagcaactgagagcagatagtaaaactgacacccaggaagctgagctactc attctcgatgagtttgctgttctttgtagagacctttatgccttctatccaatgttgata cgttatgtagacaacaacagagccaactggctaaagaaaccagatgcagattctgatgaa ctatttcgaatggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaaga gaagaacaaaattttgtgattcagaatgaaatcaacaatttggcatttttaacaggagac accaaaagcaagatgtctaaatctggaggacaagatcaagagagaaagaaatcaaaacgt agaggggatttgtactccatacaaacatccttgattgtagctgcacttaaaaagatgctt cctattggtttgaatatgtgtactcctggagatcaagagctcatctctttggctaagact agatacagccatagggacactgatgatgaagtcaaagaacatttacgtaacaacttacat ttgcaggaaaagtctgatgatccagctgtgaaatggcagctaaatctgtacaaagacatt ttgaagagtgatgaacctactgatcctgagagaaatgtggaacgtgtgcagaggatatca gctgctctgtatcatctggaacaggttgaacaaccactgaggtcaaagaaagctgtttgg cacaaactcctgtcaaaacaacgcaaaagggctgttgttgcatgtttcagaatggcacca ttatacaacctgccaagacacaaaattagcaatttcttcctgagcacctttcaacgtgtt tggctggaaaaagtacatgaaaaaactcagtatgacaggcttatactcaagttaacgaca cctccaaaaaaagaggaagaggaagaggaagagactgagaaaaaacagcctgatccactt catcagatcatcctctattttagtcgcagtgctctcacagagagaagcaaactagaagat gatcctttatatattgcctattccgccatgatggcaaagagctgtcaggaggaggaagaa gaggaagaagaagaaaaagaaaagacatttgaggagaaagaaatggaaaaacagagaact ctctatcagcaagctcgcttgcatgatcgtggagctgctgagatggtccttcagatgatt agtgcaagcaaaggtcatccaggacccatggttgttgaaacactaaaacttggtattgct attctaaatggtgggaatacaatagttcaacagaaaatgctagactacctgaaggagaaa aaggatgctggattttttcaaagtctctctggcttgatgcagtcctgcagtgttcttgac ttgaatgcgtttgagagacaaaataaagcagaaggcctggggatggttactgaagaagga actctcatcgttcgtgagcgtggtgaaaaagtgttgcaacatgatgaatttactcgagat ctatttagatttttacaactgctctgtgaagggcataacaatgattttcaaaattaccta cgtactcagatgggcaacaccacaacagtgaatattatcattagtacagttgactatctc ttgcgtcttcaggaatcaatcagtgacttctattggtactattcaggaaaggatttcatt gatgaatcaggacaacgtaacttctctaaagctttggctgtcaccaaacaaatattcaat tcccttacagaatatatccagggcccttgcataggtaatcaacagagtctggctcacagt aggctgtgggatgcagttgttggctttcttcatgtctttgccaatatgcagatgaaactt tcacaggactctgctcagattgaattgcttaaagaactgctagatctgctaaaggatatg gtagtgatgctcttgtcactgcttgaaggtaacgttgtaaatggaactattggaaaacaa atggtagacacgcttgtagaatcatctagcaatgtagaaatgattttgaagttctttgac atgttcctcaagttaaaagatctgactaactcagatgctttcaaagagcatgaccctgac ggtaaaggcatcatttcaaagaaggaattccagaaatcaatggaagctcaaaaacaatac gtacagtcagagattgaattcctactatcctgtgcagaagccgatgaaaatgatatgttt aactatgttgattttgtggaaagattccatgaaccagccaaagacattggatttaatgta gcagtattgctaacaaacctttcggagcacatgcctaatgattcacgccttcagagctta cttgaacctgcggaaagtgttcttaattactttgaaccataccttggccgtattgaaata atgggtggagccaagaaaatagaaagagtttactttgaaatcagtgaatccagtagaatg cagtgggagaagccacaggtgaaggaatccaaaaggcagttcatatttgatgttgtaaat gaaggtggagagcaagaaaaaatggaactctttgtgaatttctgtgaagacacaatcttt gaaatgcagttagcatcccagatctctgaaacggattcatctgagaggcctgaggaagag gaagaggcagagccttgttatgtagtggatattggagatgatgaggaagaagaaaagtcc ctggaatctgcttcggcttttgcaatggcctgtgttgcagtgaagaagaatgttgccaac ttttttaaaatggccactgtaaagaacctaaggaaacaatacaggaaagttagaaagatg acagtaaaagagatggtgaaagtgtttttctcctttttctggatcctatttgtagggatg ttccaactgttctttacgatagtgtggggaattttccagattctttggagcactgtattt gggggtggcctggttgaaggagccaagaacattaaagttactaaaatattaggggacatg cctgacccaacacagtttggaatccatgatgatgttatggaagcagaaaaagctgaaggc gctgagcatggcgtcagagctgaacttgtgcagtttgtgaagggtgaaaagggagaaact gacatcatctcagacatttttggcattcatacaaagaaagaaggtggctcaaaacatggt catgacgctggacttggagatattgcagaaatccttggtgctgatacccagtcgtctttg gaaaacacagttcgtaagaaaaaaggattacagatatctgaaattgcaaaagaagctgaa gcggaaagaaaagcagaagctgagaaggccgacatggaagatggtgagaaacaagatata gcaaaggaagtacaatctgagcagctagaagagggaaaaatgaagaaaaagaagcgaagg catggacaaaaaattgagaaaccagaggctgtgatggctaacttcttcaaagctttggaa atttatcaaataaaaatgcttcactacttggcaagaaatttttataacttaaggtttctt gctctatttgttgcatttgccatcaactttattcttctattttacaaggtgacagaagag ccacttgatgaagtagaggaagactctaatctctggaactcttttgatgaagaggacgag gaggagggcatggtgttttttgttttagaagaaagtacaggttacatggcacctgctctc agggcattggcagttattcatactatcatctcctttgtctgtgtgattggatactattgt ttaaaggtccctctggttgtattcaagagagaaaaggaggtagctagaaagctggaattt gatggactgtacataactgagcagccatctgaagatgatattaaaggacaatgggatcgc ctggttataaatactccgtcctttcctaacaattactgggacaaatttgtaaaacggaag gttattaacaagtacggagatttatacggagcagagcgcatagcagaacttttgggtttg gacaaaagtgctcttgattttagtccagtggaagagagcgaaccagaagaggcatctctt gtatcatggttaagctccattgatacaaagtaccacgtttggaagcttggagttgttttc actgataattcatttttgtacttagcttggtacacaactatgtctatccttgggcactac aacaacttcttctttgctgctcacctgctggatatcgctatgggtttcaagacactgcga accattttgtcttcagtcactcacaatggcaaacagcttgtgcttactgtaggactcctc gctgtagtagtctacctttacactgttgtggcgttcaacttcttccgcaaattctacaac aaaagtgaagatgaagatgaaccagacatgaaatgtgatgacatgatgacgtgttacctg ttccacatgtatgtgggggtaagagctggtggtggcattggagatgaaattgaggatcct gctggagacccttacgaaatgtatcgcattgtctttgacatcacatttttcttctttgtc attgttatcctactggccattattcaaggtctgattattgatgcttttggtgaattaaga gaccagcaagaacaagtaagagaagatatggagaccaaatgttttatttgtggaattggc aatgactattttgacacaaccccacatggctttgaaacgcatactttgcaagaacacaac ttggcaaactatctgttctttttaatgtatctcattaacaaggatgaaactgagcatact ggccaggagtcatttgtgtggaagatgtaccaagaaaggtgttgggattttttcccagca ggtgactgcttccggaagcagtatgaggatcagcttggctaa

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