Bacillus cereus ATCC 14579: BC0258
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Entry
BC0258 CDS
T00127
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bce
Bacillus cereus ATCC 14579
Pathway
bce00300
Lysine biosynthesis
bce00550
Peptidoglycan biosynthesis
bce01100
Metabolic pathways
bce01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bce00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BC0258
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BC0258
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BC0258
Enzymes [BR:
bce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BC0258
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HTH_PafC
Motif
Other DBs
NCBI-ProteinID:
AAP07327
UniProt:
Q81IU0
LinkDB
All DBs
Position
232054..233418
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AA seq
454 aa
AA seq
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MLKQVEQMVNGTELAEQYEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENG
AVATLWMKDVANPPENLPVIFVEDTLSALQMLAKNYRDQLDVKVVGVTGSNGKTSTKDIV
TSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLARPNA
AIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPGMNLAAETV
TFGDARANDYYPTTVTLQATGTHFKMNRDENISFYLPVLGKHNVYNTLASMAIAKHFGVT
WEEMKEGLVTLQMTGMRMEIVKTNSGLTIINDAYNASPTAMEAAFHLMNGLDGFAKKIVV
LGDMLELGDQEVQFHYEVGKLIDPAKISHVFTYGRLGAQIAEGAKINFPNERVKAYDNKE
ELVKDLQAVVDVKDVVLIKASRGMKLEEVITMLK
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgttaaagcaagtggaacagatggtaaatggtactgaattagcagagcaatatgaggga
attactattcaaggcgtgtctattgatacgagaaaaattgaaaaaggaaacttgtatgtt
ccgattcaaggggagcgcttcgatggacatgcttttgtagataaagctgttgaaaatgga
gctgtggctacattatggatgaaagatgtagcgaatccacctgagaatcttccggttatt
tttgtagaagacacgctatcggcattgcaaatgttagcgaaaaactatcgcgatcaattg
gatgttaaagttgtaggtgtaacgggtagtaacggtaaaacatctacgaaagatattgta
acaagtcttcttgcgactaaattcaaagtgcaaaaaacagaagggaacttcaataaccat
atcggattacctcttaccattttaaacttagaagaaaatacagaagtagcagtattagag
atgggtatgtcaagccgaggcgaaattgaattcttatctaagttagctcgtcctaatgca
gctatcattacaaatattggtgaggcacatttaatggatttaggatctcgtgaggcaatt
gctgaagcgaaattagaaattgttacaggattacaagaaggtggcgtgttcgtatataac
ggagatgagcctttattaacgaatcgtgttcctggaatgaatttagcagcagaaacggtt
acgtttggtgatgcaagagcaaacgattattatcccacgactgtaacattacaagcaact
gggacacatttcaaaatgaatagagatgaaaatatttcattctacttaccggtgttagga
aaacataatgtgtataatacacttgcttcaatggcaattgcgaaacattttggtgtaacg
tgggaagagatgaaagaaggtttagtaacacttcaaatgacgggcatgcgtatggaaatt
gtgaaaacaaatagtggtttaacaattatcaacgatgcttataatgcaagcccgacggct
atggaagcagcattccatttaatgaatggtttagatggttttgctaaaaaaatcgttgtg
ctcggtgatatgttagaacttggagatcaagaagtacagttccattatgaggtaggaaaa
ttaatcgatccagcaaaaatctcacatgtattcacatacggtagattaggggctcaaatt
gctgaaggagcaaaaattaatttccctaatgaacgtgtaaaggcgtatgataataaagaa
gagttagtaaaagatttacaagcagtagtcgatgtgaaagatgttgtattaataaaagca
tctcgcggtatgaaattagaagaagtaattacgatgttgaaataa
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