Burkholderia cenocepacia H111: I35_2881
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Entry
I35_2881 CDS
T03804
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bceo
Burkholderia cenocepacia H111
Pathway
bceo00290
Valine, leucine and isoleucine biosynthesis
bceo00620
Pyruvate metabolism
bceo01100
Metabolic pathways
bceo01110
Biosynthesis of secondary metabolites
bceo01210
2-Oxocarboxylic acid metabolism
bceo01230
Biosynthesis of amino acids
Module
bceo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bceo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
I35_2881
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
I35_2881
Enzymes [BR:
bceo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
I35_2881
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CDN61404
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All DBs
Position
1:3109914..3111560
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AA seq
548 aa
AA seq
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MMRNPQDKYRPFEPVRLNGRRWPARTIERAPVWMSTDLRDGNQSLIEPMSIEQKLEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIDDKRIPDDVTIEVLVQSREDLIARTFDALEGV
PRAIVHLYNAVCPSFRRIVFGMSKNDVKALAIDGTRIIKAHAAARPETHWTFQYSPETFS
MTELTFAREICDAVAQTWRPTRDHKMIVNLPATVEAATPNVFADQIEWMDRNLAYRDSIV
LSVHPHNDRGTAVAAAELALLAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNQIPVHPRHPYAGDLVFTAFSGSHQDAIRKGFAQQRPDAIWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATFLLERGMGFTPTRRVQIEFSHAVQTLADASGEE
VTGDTICALFAREFFETDGPAARHGIGARWQNREIALAPAADATPDDAVRRFAAAFASAA
GATIDIASCESTRTADGRVAVSVGCRVGDAPLRHGVGVHADAASAALDAVVSAINRSAWH
CADRRAAA
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgatgcgcaatccgcaagacaagtaccgtccgttcgagcccgttcgcctcaatggccgc
cgctggccggcccgcaccatcgagcgtgcgcccgtgtggatgagcaccgacctgcgcgac
ggcaaccagtcgctgatcgagccgatgagcatcgagcagaagctcgagttcttcgaaatg
ctggtcgccatcgggttcaaggagatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtccgcaagctgatcgacgacaagcggattcccgacgacgtgacgatcgag
gtgctcgtgcagtcgcgcgaagacctgatcgcccgtacgttcgatgcgctcgaaggcgtg
ccgcgcgcgatcgtgcacctgtacaacgcggtctgcccgtcgttccgccgcatcgtgttc
ggcatgtcgaagaacgacgtgaaggcgctcgcgatcgacggcacgcgcatcatcaaggca
cacgcggccgcgcgcccggagacgcactggaccttccagtactcgccggaaaccttcagc
atgaccgagctgacgttcgcgcgcgagatctgcgacgcggtcgcgcagacgtggcgcccg
acccgcgaccacaagatgatcgtcaacctgccggccaccgtcgaggccgcaaccccgaac
gtgttcgccgaccagatcgaatggatggaccgcaacctcgcgtatcgcgacagcatcgtg
ctgtccgtgcatccgcacaacgatcgcggcaccgcggtcgcggcggccgaactcgcgctg
ctcgcgggcgccgaccgcatcgaaggctgcctgttcggcaacggcgagcgcaccggcaac
gtcgatctcgtcacgctcgcgctgaacctctacacgcaaggcatcgacccgggcctcgac
ttctccgacatcgacgccgtgcgccgcgtcgtcgaacgctgcaaccagattcccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttttccggctcgcaccaggac
gcgatccgcaagggcttcgcgcagcagcgccccgatgcgatctgggaagtgccgtacctg
ccgatcgacccggcggatctcggccgcagctacgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgaccttcctgctcgaacgcgggatgggcttcacgccgacgcgc
cgcgtccagatcgagttcagccatgcggtgcagacgctcgccgacgcatcgggcgaggaa
gtgacgggcgacacgatctgcgcgctgttcgcgcgcgaattcttcgagacggacggcccg
gccgcgcgccacggcatcggcgcgcgctggcaaaaccgcgagatcgcgctggcgcccgcc
gccgacgcgacgcccgacgacgccgtgcgacgtttcgccgcggcattcgcgagcgccgcc
ggcgccacgatcgacatcgcgtcgtgcgaatccacgcgcacggcggacggccgggtcgcg
gtatcggtcggctgccgggtcggcgacgcgccgctgcggcacggtgtcggcgtgcacgcc
gatgcggcgagtgcggcgctcgatgcggtcgtcagcgcgatcaaccgctcggcatggcac
tgcgcggatcgccgcgcggcggcctga
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