KEGG   Burkholderia cenocepacia DWS 37E-2: DM40_745
Entry
DM40_745          CDS       T03488                                 
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase
  KO
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
Organism
bcew  Burkholderia cenocepacia DWS 37E-2
Pathway
bcew00270  Cysteine and methionine metabolism
bcew00480  Glutathione metabolism
bcew01100  Metabolic pathways
bcew01240  Biosynthesis of cofactors
Module
bcew_M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:bcew00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    DM40_745 (gshA)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    DM40_745 (gshA)
Enzymes [BR:bcew01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     DM40_745 (gshA)
SSDB
Motif
Pfam: Glu_cys_ligase VirE2
Other DBs
NCBI-ProteinID: AIO40322
UniProt: A0AA86KJR0
LinkDB
Position
1:complement(807153..808766)
AA seq 537 aa
MSNTMTHRQSELLLNRLEALSSGPTRQHLPDGLRGIEKESLRVTRDGMIAFTPHPRALGS
ALTHPSLTTDYSEALIELITPAEADASITLERLDDLHRYVYASLGDEMLWNDSMPGLLPA
DDEIPIADYGTSNIGRLKTVYRRGLAYRYGRTMQCIAGIHYNYSLHEEVWRRLHAEEGST
ATLVDYQSERYLAQIRNFRRRSWLLMYLFGASPALDTKFLRGKPHKLDAFDADTLYLPYA
TSLRMSDLGYSNTTAQAALQVDYNTLPGYLDALSKAVSEPYPPYEAIGTHRDGEWIQINT
NVLQIENEFYSTIRPKRITYSGERPLHALASRGVQYIEVRCLDIDPFEPTGIALETARFI
DAFLLACALDESPALDCDGYKEANANFGSVTMEGRKPGLTLMRDGQPVTLQAWADDLMTD
IETVGRRLDEIRGGDEHARAIAAQREKLADPERTPSARVLRTMRENGQSFLAFARAHSEA
HAAHFRANPPSAETMRAEQALAAKSLAEQAELEAKEAGSFDAFVAAYRAYTLNRFSV
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgtcgaacaccatgactcaccgccagtccgaactgctgctgaatcgtctcgaagcgctg
agctcgggcccgacgcggcagcatctgcccgacggcctgcgcggcatcgaaaaggaaagc
ctgcgcgtgacgcgcgacgggatgatcgcgtttacgccgcatccgcgcgcgctcggttcg
gcactcacgcatccgtcgttgacgaccgactattccgaagcgctgatcgaactgatcacg
ccggccgaagccgacgcttcgatcacgctcgaacgcctcgacgatctgcatcgctacgtg
tacgcgtcgctcggcgacgagatgctgtggaacgactcgatgccgggcctgctgccggcc
gacgatgaaatcccgatcgcggactacggcacgtcgaacatcggccgcctgaagacggtg
taccggcgcggcctggcgtatcgctacggccgcacgatgcagtgcatcgccgggatccac
tacaactattcgctgcacgaggaagtgtggcggcgcctgcacgcggaagagggctcgacg
gccacgctcgtcgactatcaatcggaacgctatctcgcgcagatccgcaacttccgccgc
cgcagctggctgttgatgtacctgttcggcgcatcgccggcgctcgatacgaaattcctg
cgcggcaaaccgcacaagctcgacgcgttcgatgccgatacgctgtacctgccgtatgcg
acgagcctgcggatgagcgacctcggttactcgaacacaaccgcgcaagcggcgctgcag
gtcgactacaacacgctgccgggctatctcgacgcgttgtcgaaggcggtgagcgagccg
tatccgccgtacgaggcgatcggcacgcatcgcgacggcgagtggatccagatcaacacg
aacgtgctgcagatcgagaacgagttctactcgacgatccggccgaagcgcatcacgtat
tcgggcgagcgtccgctgcatgcgctcgcgtcgcgcggcgtccagtacatcgaagtgcgc
tgcctcgacatcgatccgttcgagccgaccggcatcgcactcgagaccgcgcgcttcatc
gatgcgttcctgcttgcatgcgcgctcgacgagagccccgcgctcgactgcgacgggtac
aaggaagcgaatgcgaacttcggcagcgtgacgatggagggccgcaagccgggcctcacg
ctgatgcgcgatggccagccggtcacgcttcaggcatgggccgacgacctgatgaccgat
atcgaaaccgtcgggcgccggctcgacgagattcgcggcggcgacgagcatgcacgcgcg
attgccgcgcagcgcgagaagctcgccgatcccgagcgtacgccgtcggcgcgcgtgctg
cgcacgatgcgcgagaacggccagtcgttcctcgcgtttgcgcgggcgcacagtgaagcg
catgccgcgcacttccgtgcgaacccgccgtcggcggagacgatgcgcgccgagcaggcg
ctcgcggcgaagtcgctggccgagcaggccgagctcgaagcgaaggaggcaggatcgttc
gacgcattcgtcgcggcctatcgcgcctatacgctgaaccgcttcagcgtgtga

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