Shouchella clausii: ABC2642
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Entry
ABC2642 CDS
T00228
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bcl
Shouchella clausii
Pathway
bcl00290
Valine, leucine and isoleucine biosynthesis
bcl00620
Pyruvate metabolism
bcl01100
Metabolic pathways
bcl01110
Biosynthesis of secondary metabolites
bcl01210
2-Oxocarboxylic acid metabolism
bcl01230
Biosynthesis of amino acids
Module
bcl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bcl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ABC2642 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ABC2642 (leuA)
Enzymes [BR:
bcl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ABC2642 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
EFhand_Ca_insen
Motif
Other DBs
NCBI-ProteinID:
BAD65177
UniProt:
Q5WEN3
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Position
complement(2769974..2771518)
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AA seq
514 aa
AA seq
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MRKINVFDTSLRDGEQMPGIALTVKEKLEIARQLERLGVDIIEAGFPASSPGDFQAVKEI
AETVKGSSITGLARAKKSDIDSAWEALKSSAEPRVHVFLATSPIHMEHKLKLTPDQVVER
AVESVRYAAEKFPHVQFSAEDANRSEWPFLKRIIEAAIDAGASVINLPDTVGYRTPEEIS
KLFEFVTENVKNIDRAILSTHNHDDLGMGVANSLAAISAGAGQVECTINGIGERAGNAAL
EEIAVALQIRSDYYQAKTGLKLSELKRTSALVSRLTSMNVPGNKAVVGANAFAHESGIHQ
DGMLKNKETYEIITPELVGATSSLPLGKHSGRHAFKTKLNELGFSGSDEKLQTIFSAFKQ
LCDKKKEVTEDDLYALIADATDDQDSTAYELTALQVTYGMNHVPTATIRLKKQDDREIEE
AGTGSGSVEAIYNTLAKMTGGNYSLADYRIQSVNGGEDALAEVHVRIQADDFEQSGRGVA
HDVLEASAKAYLHAVNRVIARKHYAKREMAKVES
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgcgaaaaattaacgtgtttgatacgtcgctgcgcgatggagaacaaatgcctggcatc
gctttgactgtaaaagagaagttagaaattgcccggcaattggaacgtctaggtgtggac
attattgaggctggttttccagcctcctcacctggcgattttcaagcagtcaaggaaatt
gctgaaacagtaaaaggttcatccattaccggtcttgctcgggccaagaaaagcgatatt
gactctgcttgggaggcgttaaaatcaagcgctgaaccaagagtccacgtttttctggcg
acatcgccgattcatatggaacataaacttaaactgactccagatcaagtagtggagcgt
gcggtagaaagcgttcgttacgcagcggaaaaatttccccacgtccagttttcggcagag
gatgcaaaccgttcagaatggccgttcttaaaacgaattattgaagcggcgattgatgca
ggcgcttctgtcattaatcttcctgatacagttgggtatagaaccccagaagaaatatcg
aaattgtttgaatttgtaaccgaaaatgtcaaaaacatcgaccgtgccattttatccact
cataaccatgacgatcttggcatgggtgtagccaattcacttgccgctatttctgcgggg
gcgggccaagtagagtgtacaatcaatggcattggcgaacgtgctggaaacgcggcgcta
gaagaaatcgctgttgctttgcaaattcggtctgattattaccaggcgaaaacagggcta
aaactatcagaactaaagcgcacaagcgcccttgtcagcaggctaacgtcgatgaatgtt
cctggaaataaagcggttgtaggagcgaacgcgtttgctcatgagtcaggcatccaccaa
gacggaatgctcaaaaacaaagaaacctatgaaatcattacgcctgaactggtcggcgct
acgtcttcattgcctttaggaaaacattctggccgtcatgcatttaaaacaaagttgaat
gaattaggtttttctggctctgacgaaaagctacaaacgattttcagcgcgtttaaacaa
ctttgcgataagaaaaaagaagtgaccgaagatgatttgtatgcattgattgccgatgca
accgatgatcaagatagcacagcttatgaactaactgcgctgcaagtcacgtatggaatg
aaccacgtaccaactgccacgattcgccttaagaaacaggatgacagagaaatcgaagaa
gcagggactggttctggaagcgtcgaagcaatctacaatacattggcaaaaatgactggt
ggcaattacagcttagctgattaccgaatccagtcggtaaatggtggagaagatgcgtta
gcggaagttcatgtgcgcattcaagcagacgatttcgaacaaagcggacggggcgtggca
catgatgtgttagaggcatcagccaaagcgtatttgcacgctgtgaaccgcgtaatagcc
cggaagcattatgcaaaacgcgaaatggcgaaggtggaaagctaa
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