KEGG   Burkholderia cepacia GG4: GEM_2957
Entry
GEM_2957          CDS       T02205                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
bct  Burkholderia cepacia GG4
Pathway
bct00470  D-Amino acid metabolism
bct00550  Peptidoglycan biosynthesis
bct01100  Metabolic pathways
bct01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:bct00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    GEM_2957
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    GEM_2957
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    GEM_2957
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:bct01011]
    GEM_2957
Enzymes [BR:bct01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     GEM_2957
Peptidoglycan biosynthesis and degradation proteins [BR:bct01011]
 Precursor biosynthesis
  Amino acid ligase
   GEM_2957
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4 TTL ATPgrasp_YheCD PPR Cellsynth_D
Other DBs
NCBI-ProteinID: AFQ49354
UniProt: A0A9W3K2Z9
LinkDB
Position
1:complement(3234341..3235282)
AA seq 313 aa
MSGIDPKRFGKVAVLFGGESAEREVSLTSGRLVLQGLRDAGVDAHPFDPAERPLSALKDE
GFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGVPTPP
FETVLRGDDYATRATEIVAKLGLPLFVKPASEGSSVAVLKVKTADALPAALSEAATHDKI
VIVEKSIEGGGEYTACIAGDLDLPLIKIVPAGEFYDYHAKYVADDTQYLIPCGLPAEQET
ELKRIARRAFDVLGCTDWGRADFMLDAAGNAYFLEVNTAPGMTDHSLPPKAARSIGISYS
ELVVKVLSLTLND
NT seq 942 nt   +upstreamnt  +downstreamnt
atgagcgggatcgatccgaaacgtttcggcaaggtggcagtgttgttcggcggcgaatcc
gccgagcgcgaggtgtcgctcacctcgggccgcctcgtgctgcagggcctgcgcgacgcg
ggcgtcgacgcgcatccgttcgacccggccgagcggccgttgtcggcgctgaaggacgaa
ggcttcgtgcgcgcgttcaatgcgctgcatggtggctatggcgagaacggccagatccag
ggcgcgctcgatttctacgggatccgctatacgggcagcggcgtgctcggctcggcgctc
ggcctcgacaagttccgcacgaagctcgtgtggcaacagacgggcgtgccgacgccgccg
ttcgagacggtgctgcgcggtgacgactacgcgacgcgcgcgacggaaatcgtcgcaaag
ctcggcctgccgctgttcgtgaagccggcgagcgaaggctcgagcgtcgcggtgctgaag
gtgaagacggccgacgcgttgcccgccgcactgtcggaagccgcgacgcacgacaagatc
gtgatcgtcgagaagagcatcgaaggcggcggcgaatacaccgcgtgcatcgccggcgac
ctcgacctgccgctgatcaagatcgtgccggcgggcgagttctacgactaccacgcgaag
tacgtcgccgacgatacccagtacctgatcccgtgcgggctgccggccgaacaggaaacg
gaactgaagcgcattgcgcgccgcgcgttcgacgtgctcggctgcaccgactggggccgg
gccgacttcatgctcgacgccgccggcaacgcgtatttcctcgaagtgaacacggccccc
gggatgaccgaccactcgctgccgccgaaggccgcgcgctcgatcggcatcagctattcc
gagctggtcgtgaaggtgctgtcgcttacgctcaacgactga

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