Bacillus cereus E33L: BCE33L0220
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Entry
BCE33L0220 CDS
T00198
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bcz
Bacillus cereus E33L
Pathway
bcz00300
Lysine biosynthesis
bcz00550
Peptidoglycan biosynthesis
bcz01100
Metabolic pathways
bcz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bcz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BCE33L0220 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BCE33L0220 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BCE33L0220 (murF)
Enzymes [BR:
bcz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BCE33L0220 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AAU20013
UniProt:
Q63GX6
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All DBs
Position
236365..237741
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AA seq
458 aa
AA seq
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MINRTLKQVEQMINGTGLAEQYEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKA
VENGAVATLWMKDVANPPENLPVIFVEDTLSALQMLAKNYRDQLDVKVIGVTGSNGKTST
KDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLA
RPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPEMNLI
AETVTFGDARANDYYPTTVTLQATGTHFKMNREENISFYLPVLGKHNVYNTLASMAIAKY
FGVTWEEMKEGLVTLQMTGMRMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFSK
KIVVLGDMLELGDQEVQFHYEVGKLIDPAKISYVFTYGKLGAQIAEGAKINFPNERVKAY
DNKEELVKELQAVVDTKDVVLVKASRGMKLEEVITMLK
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgataaatcgaacgttaaaacaagtagaacaaatgataaatggtacgggattagcagag
cagtatgagggaattactatacaaggggtgtctattgatacgagaaaaatcgaaaaaggg
aacctatatgttccgattcaaggtgaacgtttcgatggacatgcttttgtagataaagct
gttgaaaatggagctgtggcgacattatggatgaaagatgtagcaaatccacctgagaat
cttccggttatttttgtagaagacacgctatcagcattacaaatgttagcgaaaaactat
cgcgatcaattggatgttaaagtgattggtgtgacaggtagtaacggtaaaacatctaca
aaagatattgtaacaagtcttcttgcaactaaattcaaagttcaaaaaacagaaggaaac
ttcaataaccatatcgggctacctcttactattttaaacttagaagaaaatacagaagta
gctgtattagaaatgggaatgtcaagccgcggggaaattgaattcttatctaagttagct
cgtccaaatgcagctatcattacgaacattggtgaagcacatttaatggatttaggctct
cgtgaggcaattgccgaagcgaaattagaaattgtgacaggattacaagaaggtggagtg
ttcgtatataacggagacgagccattattaacgaatcgtgttcctgaaatgaatttaata
gctgaaacagttacgtttggtgatgctagagcaaatgattattatccaacgactgtaacg
ttacaagcaactgggacgcattttaaaatgaatagagaagaaaatatttcattctatcta
ccggtattagggaaacacaatgtgtataatacgcttgcttctatggcaattgcgaaatac
tttggtgtaacgtgggaagagatgaaagaaggtttagtaacacttcaaatgacaggcatg
cgtatggaaattgtaaaaacagacagtggattaacaattatcaatgatgcctataatgca
agtccaacagctatggaagcggcattccacctaatgaatggtttagatggattctctaag
aaaattgttgttctcggtgatatgttagagcttggagatcaagaagtgcagtttcattat
gaagtaggtaaattaattgatccagcaaaaatttcctatgtgttcacatatggtaaatta
ggagctcaaattgctgagggagcgaaaattaatttccctaacgaacgtgtaaaggcttat
gataataaagaagagttagtaaaagagttgcaagcagtggtcgatacaaaagatgttgta
ttagtaaaagcatctcgcggtatgaaattggaagaagtaattacgatgttgaaataa
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