Bacteroides difficilis: ACNOGP_08420
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Entry
ACNOGP_08420 CDS
T11389
Name
(GenBank) bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
KO
K01798
Alr-MurF fusion protein [EC:
5.1.1.1
6.3.2.10
]
Organism
bds Bacteroides difficilis
Pathway
bds00300
Lysine biosynthesis
bds00470
D-Amino acid metabolism
bds00550
Peptidoglycan biosynthesis
bds01100
Metabolic pathways
bds01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bds00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACNOGP_08420
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
ACNOGP_08420
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACNOGP_08420
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACNOGP_08420
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
bds01011
]
ACNOGP_08420
Enzymes [BR:
bds01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.1 Acting on amino acids and derivatives
5.1.1.1 alanine racemase
ACNOGP_08420
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACNOGP_08420
Peptidoglycan biosynthesis and degradation proteins [BR:
bds01011
]
Precursor biosynthesis
Amino acid ligase
ACNOGP_08420
Racemase
ACNOGP_08420
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ala_racemase_N
Ala_racemase_C
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
XPI38049
LinkDB
All DBs
Position
2276251..2278809
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AA seq
852 aa
AA seq
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MSYAIESIAQSIGARRVGEYEATIDWLLTDSRSLSFPEETLFFALTTKRNSGVRYIPELY
ARGVRNFVVSEEEFKQVENGELRIESAMQGDDAQPILNSQLSTLNFSSILNFLIVPNPLK
ALQKLAEVHRERFNIPVIGITGSNGKTIVKEWLHQLLSPDRCIVRSPRSYNSQIGVPLSV
WQLSEEAELGIFEAGISEMGEMGALKRMIKPSIGILTNIGGAHQENFFSLQEKCMEKLTL
FKDCDVVIYDGDNELISNCVAKSMLTAREIAWSRTDIERPLYISRVTKKEDHTVIAYRYL
NMDNTFCIPFIDDASIENVLNCLAACLYLMTPADQITERMARLEPIAMRLEVKEGKNNCL
LINDSYNSDLASLDIALDFLVRRSEKKGLKRTLILSDILETGQSTATLYRRVAQLVQSRG
IDKLIGVGPEISSCAARFDDGIERYFFPNTEALLKSELLKSLHSEVILIKGSRVFNFDLV
SEALELKVHETILEVNLGAMVENLNHYRSMLRHPETKMICMVKASAYGAGSYEIAKTLQE
HHVDYLAVAVADEGSELRKAGITSSIIIMDPELTAFKTMFDYKLEPEVYNFHLLDALIKA
AEKEGITNFPIHVKLDTGMHRLGFEAEDIPLLIRRLKNQNAVIPRSVFSHFVGSDSPQFD
AFTRQQIELFEKGSQELQAAFSHKILRHICNTAGIERFPGAQFDMVRLGIGLYGVSPIDN
SIIHNVSTLKTTILQIRDVPEEDTVGYSRMGHLIRPSRIAAIPIGYADGLNRHLGRGNAY
CLVNGKKAPYVGNICMDVCMIDVTDIDCREGDQAIIFGDDLPITVLSDKLDTIPYEVLTS
ISTRVKRVYYQD
NT seq
2559 nt
NT seq
+upstream
nt +downstream
nt
atgtcatacgcgattgaatccatagcccaaagtatcggcgcccgccgtgtgggtgaatat
gaagcgactatcgattggctcttaacagatagccgttccctgagttttccggaagaaacc
cttttctttgcattaaccaccaaacgcaatagtggagtccgctacatccccgaactgtac
gcccggggtgtccgaaactttgtggtctcagaggaagagtttaaacaagttgagaatgga
gagttgagaattgagagtgctatgcagggtgatgatgcgcagccaattctcaattctcaa
ctctcaactctcaatttctcctccattctcaatttcctcatcgttccgaaccctctgaaa
gcattgcagaaactggctgaggtacatcgggagaggtttaatattcctgtaatcggtatc
accggaagcaatggaaaaaccattgtgaaagagtggttgcaccaattgctgagtccggac
cgttgtatcgtccgttctccgcgtagttataattcgcagattggtgttccattgtctgtg
tggcaactttccgaagaagcagaattgggaattttcgaggcgggtatttctgagatgggg
gagatgggtgcattgaaacggatgataaagccttctatcggtattctgacgaatatcggt
ggtgctcatcaggaaaacttcttctcattgcaggagaagtgcatggaaaagctaaccctt
ttcaaagattgtgatgtcgtgatttatgatggtgataatgagttgattagcaattgtgtg
gcgaaatcaatgctgaccgcacgtgagattgcctggagccgtacggatattgaacgtccg
ttgtacatcagtcgtgtgacaaagaaagaagaccataccgttatcgcttaccgttatctg
aatatggataacactttctgcattcctttcatcgacgacgcttctatcgaaaacgtacta
aactgcttggctgcctgtctttacttgatgactcccgccgatcagataacggaacgcatg
gcacgtctcgaaccgattgccatgcgccttgaagtgaaagagggaaagaataactgccta
ttgattaatgatagctataattcggatctggcctctctggatatagctcttgacttcctg
gtgcgccgttctgaaaaaaaaggactgaaacgtacgctgattctgtcggatattctggaa
acgggacagagtactgccacgctttatcggcgtgtagcccaactggtgcagagtcggggt
attgataaattgataggagtaggaccggaaatttcttcgtgtgccgctcgttttgacgac
gggatagaacgttatttcttccctaataccgaagcgcttcttaaatcggaactgctcaaa
tcccttcattcggaagtgattctgataaagggttctcgtgtgttcaacttcgatctggtg
tccgaagcactcgaactgaaagtgcatgaaacgatactggaggtaaatctgggtgcgatg
gtggagaacttgaatcattaccgctccatgttgcgccatcctgagacgaaaatgatctgc
atggtgaaggcgtcggcatacggagccggttcatacgagatagccaagactttgcaggaa
catcatgtcgattacttggctgtggcggtagccgatgaaggttccgaactgcgcaaagcg
ggtatcacgtcctctatcatcatcatggatccggagcttacagcgttcaaaacgatgttt
gactataaactggagccggaagtttataatttccatttgcttgatgcgctgattaaagcc
gcagaaaaggaaggaatcaccaatttccctattcatgtgaaactggatacgggaatgcat
cggctgggttttgaagcggaagatatccccttgcttatccgtcgcttgaagaatcagaat
gcggtaattccccgttcggtattctctcatttcgtgggcagtgattctcctcaatttgac
gctttcacccggcagcaaatcgagttgtttgaaaaaggctcgcaagaattgcaggcggct
ttctcgcataagattttacgccatatctgcaatacggcaggaatcgagcgttttcccgga
gcacagtttgacatggtacggctaggtatcggactttacggagtgagtccgatagataat
tcgattatacataatgtcagcacgctcaagacaaccatacttcagattcgggatgtcccc
gaagaagatacggtgggatatagccggatgggacacttgatacgtccgtcccgtatagcc
gctattcctatcggttatgccgatggcctgaaccgacacttggggcgtggaaatgcttac
tgtctggtgaacggcaagaaagccccttatgtgggcaatatctgcatggatgtctgtatg
atagacgttacggacatcgactgccgtgaaggcgaccaagctataatcttcggtgacgac
ctgccgatcacagtattgtccgacaagctggatacgattccgtacgaagtgctgactagc
atatcgacgcgggtgaaacgggtatattatcaggattag
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