Bacillus freudenreichii: NCTC4823_00497
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Entry
NCTC4823_00497 CDS
T06767
Symbol
leuC_1
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
bfd
Bacillus freudenreichii
Pathway
bfd00290
Valine, leucine and isoleucine biosynthesis
bfd00660
C5-Branched dibasic acid metabolism
bfd01100
Metabolic pathways
bfd01110
Biosynthesis of secondary metabolites
bfd01210
2-Oxocarboxylic acid metabolism
bfd01230
Biosynthesis of amino acids
Module
bfd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bfd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NCTC4823_00497 (leuC_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC4823_00497 (leuC_1)
Enzymes [BR:
bfd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NCTC4823_00497 (leuC_1)
4.2.1.35 (R)-2-methylmalate dehydratase
NCTC4823_00497 (leuC_1)
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Paralog
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Motif
Pfam:
Aconitase
AcnX_3rd
BDV_P10
Motif
Other DBs
NCBI-ProteinID:
VEF46514
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All DBs
Position
1:534907..536322
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AA seq
471 aa
AA seq
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MGKTIIEKIWEKHVVHSEEAKPDLIYIDLHLVHEVTSPQAFEGLRLNGRKVRRPDLTFAT
MDHNVPTRTNEEVTDPIAKKQMTTLEKNCAEFGVPLAGMGHPDQGIVHVIGPELGLTQPG
KTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQKPKTMQVKVNGELGAGVTAK
DLILAIIAKHGVDVGTGHVMEYTGEAIRKLTMEERMTVCNMSIEAGARAGLISPDETTFE
YLKGREHVPAGEEYEKLVEEWKQLASDDDAEYDSVIEINADEVEPFVTWGTNPSMGVRIS
ESIPSPENAASDSEKESIEQALEYMGLTGGAKMTDVDIQYVFIGSCTNSRIEDLRAAAEV
LKGRKVSEGVTAIVVPGSRTVKAQAEEEGLDQIFLESGFEWRETGCSMCLAMNADQVPAG
KRCASTSNRNFEGRQGNGSRTHLVSPAMAAAAAVEGRFVDVRHLMKGEVHA
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgggcaaaacaattatagaaaaaatatgggaaaaacatgttgttcatagtgaggaagca
aagccggatctcatctatatcgatcttcaccttgttcatgaggtaacatctccgcaggcg
tttgaaggattgcgtttaaacggccgtaaggtgagaagacctgatcttacgtttgccacg
atggaccacaatgttccgaccagaacgaacgaagaagtgacagatccaattgcgaagaag
caaatgacaacattggagaaaaactgtgcagaatttggagtgcctcttgctggtatgggt
catcctgatcaagggattgtccatgtaatcggacctgagctcggcttaacacagcctggt
aaaacaatcgtgtgtggagacagtcatacttccacacacggtgcatttggcgccctcgct
tttgggattgggaccagtgaagtggagcacgttctttctacgcaaaccctatggcagcaa
aagccgaaaacaatgcaagtcaaagtgaacggggaacttggtgccggcgttactgcgaaa
gacttgattcttgcgatcattgccaagcatggtgttgacgtgggaacaggccatgtcatg
gaatatacaggtgaagctatccgcaagttgacaatggaagagcgcatgactgtatgtaat
atgtctatcgaagccggagcaagagccggtctcatcagcccggatgaaacgactttcgaa
tatttgaaaggccgtgagcatgtgccggccggtgaagaatatgagaaattggtggaagaa
tggaaacagctcgcatccgatgatgatgctgaatatgattcagtcatcgagatcaatgca
gatgaagttgagccgtttgttacatggggaacgaatccttccatgggtgtcagaatttcg
gagagcattccatctcctgaaaatgcggcgagcgattccgaaaaagaatcgattgaacag
gcacttgagtatatgggtctgaccggtggtgccaagatgacagatgtggacattcaatac
gtgttcatcggatcatgtacgaattcccgtattgaagacttgagagccgctgcggaagta
ttgaagggaagaaaggtaagcgaaggtgtaacagcgatcgttgtaccaggttcccgtaca
gtaaaagcacaggctgaagaggaaggccttgatcaaatcttccttgaatccggatttgaa
tggcgtgaaacagggtgcagcatgtgtcttgcgatgaatgcggaccaggtccctgcaggc
aaacgatgcgcatctacatccaaccggaactttgaaggacgccaagggaacggatcccgt
acacatctagtcagcccggcaatggccgcagctgcagccgtagaaggcagattcgttgat
gtgaggcatttgatgaaaggggaggttcacgcatga
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