Brachyistius frenatus (kelp perch): 138621235 Help Entry 138621235         CDS       T10614                                  Symbol obscna Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism bfre  Brachyistius frenatus (kelp perch) Pathway bfre04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:bfre00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     138621235 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bfre01001]     138621235 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bfre04131]     138621235 (obscna) Enzymes [BR:bfre01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      138621235 (obscna) Protein kinases [BR:bfre01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    138621235 (obscna) Membrane trafficking [BR:bfre04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     138621235 (obscna) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 C1-set Izumo-Ig SOS1_NGEF_PH RhoGEF Ig_CD22 V-set_CD47 C2-set_2 ABC1 Sp38 Kdo fn3 Kinase-like PH IQ_SEC7_PH IQ APH RHG20_PH Motif Other DBs NCBI-GeneID:  138621235 NCBI-ProteinID:  XP_069555223 LinkDB All DBs Position Unknown AA seq 6121 aa AA seqDB search MGDNKPGGIVAAVKNRLQVVKGLEDVEMSESESCSFEVTLNLAYIEGMWTRDGMLLKSKP NCRISTHGKKHSLILNRVALGDAGLFSFQANGIQTSGRLTVTARDIHIVKELEDVDTMER QPVNFLCEVNQVDVDARWYREDCRIRPGDSIKIRHQGKSHTLFFKSVRPEHAGEIRFTAE RVSSYATLTVKELPVQILRPLRVKIAMYRHRGLLECQVSRPNAQVKWYKNRKELLPSKKY QLISQDIYRQLTIDDICSSDEDTYTCDAGDDKTTCQLLVEEQAISIVRGMKSVEVMEPEP ALFQVETSLKSGRPPKWILSGEVLELCAAVDIDREGTLHSLCLTSTESSMSGPVVFVAGK SRSTAQLSVKERPLQVVHHLDDVEVKENSSVTLSCEFAPSPRAVQWFKGRTALKTSNKYS MKREGKQAELIIHGLTGMDAGQYRCMAGGSQSTAHVKVEVKTLKLVKHLEPVEIEEDGIA TFSCELNYVVANVEWLLNNIRLYSNAINRIQHMGTMHSLIIKKLWPQESRVTFKTSLLTE TTTLKVKERPAVFLRSLEDATGEEQGEVCLQCEISKEAVTPVWRKDGTVLTADDKYELLQ FGKSRALIIHSLSKDDAGQYTCDLGTSQTKAKVTVHDLHISIVQRMKTTSVLEGENCTFE CHLSHDLDDEPSWTINGQGVVTNSHIQIINNGRKYTMTIRDAVVTDAGDVVFTIKDFSCR TMLFVKEKPVHIFRELLNVKAVPGEDAELSCEITKPEVTIRWLKNGHLIRQSPKYEMSVE KNLARLVIKNSTIRDSGEYCCEAEGVASRGKLEVRELQHTFARELRDTRAEDKGKVTLEC ETRRPAKRVTWLKGMVELRSGRKYVMRQKGVVLSLTITCLEKLDTDIYTCDVGTMQSRAQ LTVQGQRVLILDELEDVECLEGDTVTFRCQICPSDYIGVKWYLDETLLYTNELNEIQMVA GGYHTLTFRQLARKDTGTISFAAGDKRSYASLLVRERRPTIIKALEDCEAIEGGGLVLSC VASKPCHILWYKDCCLMWNSSRYFASRSGCEARLTIREVSNSDAGVYECSAGSVTTRAVV TVKAIPAEFTQLLKTMEAKEGEAVTLTCEYSLPGVQCHWRRGFESIRTGDKYVMKQRRTI NSLTIKALKPEDSGEYTCQCRDHHTTASLRVHAIPITFIQQLKNMQAEEGSSVILRCEIS KPGIPVEWRKGHELLKNGVKYQIRKRDTTSELLIWKPVPEDGGVYSCVCADQTTSATVKI TALPVTFKQKLRNVLIEEGNTAALRCELSKPSHIVEWRKRGNELIRNGEKYHMRQRDMLI ELRILDVTPDDSNIYTCICGNIETTATLTVNALPVTFKQKLKNLQVAEGHNITLSCEISK PGVPVEWRLGGDPLENGEKYQIKQKDSALELIIRDAVVEDSGVYICVCREQRTKATVKII AVPATFKVSLKSQEGEEGNSVTLHCELSKVGVPVQWQKEGQVLSEEVSRGKYQMKLERKT ALMTIINIQPEDAGKYSCITGDEKTTAEVKVKPLPITFKRELQCLVVKEGDSGVFCCELS KPGAPVGWRKGRVLLKPGEKYEMKQDGRLTKLIISDVEESDAGKYTCKTKDSQSTAELTV KGLPPSFKLLLVDQEVTEGNSVVLRCELNKPAQSVEWRKGGELLKNGDKFQMRKKDLQVE MKVSELSMEDAGDYTCICGEQKTTAKIRVNEQPIKFLQELKNIQVQEGNGVTLGCELSKP GGPVEWRKGDNVLTSGEKYQVKQSGSMLELFIRKSLPDDSGSYSCVCDDIKTMATVIITA IPVTFKQKLKNQEAVEEGYVTLRCELSKSGVPVEWRRDAQLLKEGEKYLMKQEGRVAEIL ITNVTLADAGEYSCLVGNVVTSADIKVRALPVTFKQEVENLEVKEGDSGAFCCELSKPGA PVDWRKGRVVLKPGYKYEMKQEGHLTKLIINNVEESDAGKYTCKTKDSQSTAELTVKAPP VTFNAKLRNQQVEEENSVTLCCELSKPGLMVEWRRGEELLKNNIKYQIKNRNSSLELTIK NTQVEDSGVYSCSYGDAKTSANVTITPIPFTFKMGLKNQEAPEGGNVFLHCELSRAGVPV QWWKGEDQLYQGGRYQMTLKGKIAEMTIRNIQPEDVGEYSCIFGEQKTTAEVNVRAAASV FFEKELESQAIMEGKSVLLSCEVSSANVPVTWKKDNTVVEEGGCYIVKKKGPTHTLEIKK LQLEDAGEYCCITRGKKTTAKLIVRERVRIVTELHDVTVTAGEDAVFVCELSHADVSEGV WWLGPSPLQKNEMNQMTCHGFQHQLVLTMTTPEETGTVAFVVGEERTSACLLVVPKPKVL FEETPKDTVVMEGETATLRCTTSDFTTLVTWRRNHIPLRNGDKYEMRKEGKINLLLIPDA EPLDTGIYSCDTGDVQSSAKLTVTELPPFFQEELQSVEAEEGCTASLYCELSKLGVPIQW RKNRQPLRASRTYEMRQDGCFLQLHIKDLKLEDSGSYSCQAGSAETTATVSVKELPPFFN KELRSVEGEEGDAASLQCELSKPRVSVQWKKNRLPLRNSRKYEMKQDGCFLQLLIKELEP EDSGSYTCQAGNAETTANVSVKELPPFFKKELLNMKAVEGGTASLCCEVSKPGVSVQWKK NKQPLRASRKYEMKQDGCFLQLNMKGLTPEDSGSYTCQTGSAETTATLSVKELPPCFIEE LQGTEAEEGGTASLYCELSKPGVSVQWKKNKLPLRASRKYEMKQDGCFLQLHIKDLKPED RGSYTCQAGAAETTATLKVTELPPFFKVDLKSVDIEEGGTASLSCEVSKPGVSVQWKKNK LPLRANRKYEMKQNDCFLQIYINDLKPEDSGSYSCQAGAAETTAIVTVKELPPVFKKDLV SVETEEGGTASLTCELSKPGVSVQWKKNKLPLRANRKYEMKQDGCFLQLHIKELKPEDSG SYTCQAGSAKTTATVAVTELPPFFKEDLQSVEADEGCPASLCCELSKPGVPVQWKKNMLP VRANTKYEMKQDGCLLQLNINELKPEDSGSYTCQAGAAETTATLTVKELAPFFSKELQTV EAEAGGTASLYCKLSKPGVSVQWKKNKLPLRASRKYEMKQDGCFLQLHIKDLKPEDIDSY TCQAGAAETTATVKVTALQPTPPKPEPLTVQPRGKGTVSKPNLTPENEKPGPPDAKPPEP KKRTRKASLTNSEKDVEPVHLKPPVLKQNNEVQKGVQLARYVEKDFEVAQNVTQVERNKE KDGESYTKADKSVRPPEEDHKVNRRVEEPARPLEKENEVFQETRQPGRYVEELLKVDHTV SQSDRVLGDTEVGLKKQKEKEPEIKQRLKQVEKPSQKTSEVEKKVKHSGTVQWKNSEDEN RPVKPVEELIRRETTKEDVKSTENEGEMDKTAEDLLKPPMRFKGKVTVEKQPVKCILKDT EETILQVLKNTYNDSEEDHKQGDHANKQVSTQAAKKPLKLVPSVNQQDNQSVEQPGKPVE KEAEFVLPKPPVRTKSKSKGGIEKQVSRDTETDQDEQQPARSVIKTNEEHPIKQSIKLLK KESEEKPTLQRNQSVTSDSEIVEKIKQPARAAEKESKQPINQPVKPMRKEPGNDQEIKLA VEPVRREKEQLTTKVAEDIPLLYISEDETFLEALTEIPANHSNVQPIVSLVVGPTTELPL QRTQASKDSLPDIDIHTEDEPEMQEAAVKIQAAFKGYKTRRDMRPVFKEVFKNQSADLHS TLTLVCIVEGKPSTVRWLKNGQEISHDHRCRIKTAETGECTLVIKNLVNSDSGIYTCEVV NKFGVTSYNGNITVEQTAQPTAAVQNPVHPPLAAITPLQLASPKPEPQDKSQSQDLPESQ AVVHTSAADAENYVESMSVSLWETYNLTEQDTHMSLQERRRSSLIAASSMSSPSDYDTAP DIMEPVETAAVIPRVVPKPVEEVAPKEDNKEITAPQPPKKLLKVKGTHDSKMRTPSPKHH QAHTPLASTVSGLESEGEEDRRETFEMYVARADCSPNSGNKDSFVLKEGQFVEVLDSVHP DRWLVRTKPTKTNPARQGWLCPAYLEKKRKEAFPQLRAPQDDLDGIGSTGEEYRRAMSQL IQGLIDGEEEFVKEMKMFISHQLNFLDSSCHVPINILNQKEIIFRNIKDIVFLHEWSILP GLRECATDDDVAMHLTKHIEYFEKYLHYMVGQAQAEACITEKAAQQYFKELIEPGKPDVP VMDFLTFLQQPVERIQTYQALLKELIKNKAKSGQSCFLLEDAFSVVSCLPWRSDNLHQVS LIENYPTPLTALGEPVRQGVFTVWEESPEIKTATRGHQRQVFLFKECIVLCKLKKDTSMN RDTYTFRNKMKLNDVQIKETVGGEERSWGLWHEHRGSMRRYTLQGHSTLVKLSWLKDLKE LQQRSSTLTNSPPVFESLLSDCKTKIGQTIKLTCKVSGSPTPVISWLKDGLPLEDDPRHI ITADRLGTCSLILDSLTAEDSGQYACYACSSMGSAGSLAKVVVQAPPRFVSRLESACLIE GEDIQFSCSTLTTPLPRIRWLKDGRELTDQQKYSIVNDPRSGILSLTVIRATEADIGQYE SELWNELGCVKCKAGLCPAYVPPTDIGNDQPQDLPPKDADSEGWSTAFVKKWLQTDFSPT SIAKMLFPPGSTEQAECSTEVDVHASTDQAAQQPLCYLEEEEEIYISEQMQEITDAPPFI QVPAEDLYVEPGQTSTFTAIITGRPTPKIQWYKDGEELAANENVKIVQQGARCSVTIVCP DGEDSGIYTCFAHNDSGHASCQAQLTVEEGPLESQEREVELGKRRKLFSVYDVHEEIGRG TFGVVKHVVHRRTGEVFAAKFLPLRSNTQTRAFQERDLLSRLAHPRVACLLDFFCTRRTL VLITEICCSHGLLDHLLLRGSVSEKEVQTYIQQLLEGVSHIHSLNILHLDIKPDNILMVY PPRDEIKICDFGFCQEIDTSRHQYSMFGTPEFVAPEIVHQEPVTVATDIWAVGVIAYLCL VCRCPFVGETDRATLLRVGEGTLNWDAPDVLYRSPEAKNFLHMVLQPDPEKRPSAFECLS QEWFQDEHAGEDTDEINTKSLKVFISKRKWQRSLTCIGSVLTLRPIPELLDAPLRDTAVT VPREHQDHSSSSPSSGSSSEYDEADSWDFFQHCSQTEEEEETEEDFDSLMERARIPEPFA KLHLDGEEEEELTLGEEEDGEIVGRRSVLQRSMSRQSVASSEVSSQHTPQRERRFSKDSS PSLYLSDGDDGSESDGGRIPRGSVIRSTFYNTSHQLSPMSARHMTLRDKFQAKKQERGRK PLRRSFSGRLNEPLIEYVEDETETNRGQRRGSVQPTMQKSCSFDSGVGLIHGNIPPHRRS RSLDEYSRRSPSSPSRAMPGEEEGSQSLKEDFTDDEVAGRNLLAILSSQRATRRRGSVAP VQGTHTSSGSSGASDFLAGDRRSSMLDREQTVGDTFVGSQGSLAESFILEHGGSESSSRL GSYEELSHGHLRGGYRSGESEGYDDQGEPLIPPSPCSFQEVKPKGSVPQAPPRNRTRSNP NLSTNNRGQPGTPVMPRPSPSLSSLQAPERPPRTKDKKEGSGLQRHASAPALEVRPPTGK SPKLGLLKIFRRQSWTGHSYSQLDDTELGPTLGEIMKPNTPTMSLRKKMRASASSLTKLF SRSSSKEDVSKGGPIVKGSASTPPESPKKRTSKLLPSFKIPAFKKSKDLPVRPCKAEVFQ LDGGGVLLVWRPVQSSDPVTYCVQYCTDGGEWTVLSEEVTESCYVVRDLTRGASYVFRVG CISKTGAGPFSDASAPVVMASHPEEIHIPLIQTESLGSKVTGSHSHTKHKSYSFLSEINR GRFSVVNLCRDVETSQVFASKISPYQAEQRPLVLREYQLLKKLHHPHLVQLHAAFIAPRY LVLVEELCPGKELLYGLAARDQYAETHVAELLVQVLSAVDYLHSRRVIHLDLKSDNMLVD DRNHLKIVDFGSAQSFTPGQPLNVEHIHGLSDSRDCRSKVYIVLPKAPEILEGQGVGPET DVWAVGVLSFIMLSADSPFHAELSWEQDRNIKKGKIQFGRCYPGLSEGALNFMKSSLNNK SWGRPTAAECLQNPWIRAHRAPHKARHSKVCFSTDKLKDYLKQKEEKRDQVRTKLQPPFF Q NT seq 18366 nt NT seq  +upstreamnt  +downstreamnt atgggagacaataagcctggaggaatagtagcagctgtcaagaaccggctgcaggtggtg aagggcttggaggatgtggagatgtctgagagtgagagctgttccttcgaggtgactctc aacctggcttacatagagggcatgtggaccagggatgggatgctgctgaagtcgaagccc aactgtcgtatcagcacgcatggaaaaaaacactccctcatactgaacagggtggctttg ggagatgccggcctgttctctttccaggccaacggcatacagacctcaggccgactcact gtcacagctagggacatccacattgtgaaggagctagaggatgttgatacgatggagcgt cagcctgtgaacttcctgtgtgaggtcaaccaggtggatgtagatgctcggtggtacaga gaagactgccggatccgacctggagacagcatcaagatcagacaccagggcaaaagtcac accctgttcttcaagtcagtcagaccagaacatgcaggagagatcagattcactgcagag cgtgtctcatcctatgcaactctaacagtaaaagagctcccagttcaaatattacgtcct ctgagggtcaagatagccatgtatcgccacagaggtctgctggagtgccaggtttcacgg cctaatgctcaggtcaagtggtacaagaacaggaaggagctcctgcccagtaagaagtac caactcatcagccaagatatctacaggcagctgaccatcgatgacatctgctcctcagat gaagacacctatacgtgtgatgcaggagatgacaaaacaacgtgtcagcttctagtggag gagcaggccatcagcatagtgcgggggatgaaatccgtggaggtgatggagccagaacct gcgttattccaggtagagaccagcctaaagtcagggaggcccccgaagtggatcttgagc ggtgaggttctggagctgtgcgcagccgtggacatagacagggagggcaccctgcacagt ctctgtctcacctccacagaaagctccatgtcgggccctgtggtctttgtggccggcaaa agtcgttctactgctcagctttctgtgaaagagcgacctcttcaggttgtccaccacctg gatgacgtggaggtgaaggagaacagctctgtgactctgagctgtgagtttgccccctct cctagggcggtgcagtggtttaaaggtcgtaccgctctgaagacctcgaacaagtacagc atgaagagagaagggaagcaagcagaactgatcattcacggcttgacaggaatggacgcc ggacagtaccgctgcatggctggaggctcacagagcacagcacatgttaaggttgaagta aaaacactaaagttggtcaaacaccttgagcccgtggaaattgaggaggacggcattgcc acattctcatgtgagctcaactacgtggtcgccaatgtggaatggctcctgaacaatatc cgcctctattccaacgccatcaacaggatccagcacatgggcaccatgcacagcctcata atcaagaagctctggcctcaggagagcagggtcaccttcaaaacaagcctattaactgag acaaccaccttaaaggtcaaagagcgcccagcggtgttcctgaggtctctggaggacgca actggagaggaacagggggaggtttgcctgcagtgtgaaatttccaaagaggcagtgacc cctgtttggaggaaggatggtacggtcctgacagctgatgataaatacgagctgctccag tttgggaagtccagggccctgatcatccattcactgagtaaagatgatgctggacagtac acctgtgacctaggcaccagtcagaccaaggctaaagtcacagtgcacgatttacacatt agcattgttcagcgtatgaagacaacctctgttctggaaggagaaaactgcacttttgag tgtcatctctctcatgatctcgatgatgaaccttcctggacaatcaatggccagggggtg gttaccaacagccatattcagatcatcaacaatggccgcaagtatacgatgaccattaga gatgctgtagtgactgacgctggagatgtggtcttcacaattaaagactttagctgcagg accatgctctttgttaaagagaagccagtgcacatcttcagggaactgctgaatgtgaag gcggtacctggtgaggacgcagagctaagctgtgagatcaccaaaccagaagtcaccatt cgctggttgaagaatggacatctgatcaggcagagccccaagtacgagatgagcgtggag aagaacctggcgcgactggtgatcaagaactctaccatcagagactctggagagtactgc tgtgaggcagaaggtgttgcttctcgtggcaagctggaggtcagagaactccagcacaca tttgcaagagagctgagagacacccgggcagaggacaagggcaaggtgaccctggagtgt gagaccaggcggccagccaagcgggtgacctggctgaaaggcatggtggagctgaggtct ggtaggaagtatgtcatgaggcagaagggtgtagtgctgtccctaaccatcacctgtctg gagaaattggacacggatatttacacatgtgacgttggtaccatgcagagccgggcacag ctgactgtgcagggtcagagggtgttgatcctggatgagttagaagatgttgagtgtctt gagggcgacactgtcacgttcaggtgtcaaatttgtcccagcgactacataggggtcaag tggtacctggacgagacgttgctttacaccaacgagctcaatgagatccagatggttgcg ggaggctaccacaccctcacatttagacagcttgcccgaaaagacactggcactatttca tttgcagcgggggacaaaagatcctacgcctcactgttggttagagagagacgtcccacc attattaaggcacttgaggactgtgaggccattgaaggaggtggcttggttttgtcctgt gtggcttccaagccatgtcacatcctgtggtacaaagactgctgtctgatgtggaactcc tccagatactttgccagtcgttctggctgtgaagctcggctcacgattcgggaggtgtcc aacagtgatgcgggggtgtacgagtgcagcgctggatctgttacaactcgggctgttgta actgttaaagccattccagcagagttcacccagttgctgaagactatggaggccaaagaa ggagaagctgttaccctgacctgtgaatactctctgcctggggtccagtgtcattggaga agaggttttgagagtatcaggactggagacaagtatgtaatgaaacaaaggaggacaatc aactctctaaccatcaaagccctgaagcctgaggactcaggagagtatacgtgccagtgc agagaccaccacacaacagcaagcctcagagtacacgctattcccatcaccttcatacaa cagttgaagaacatgcaagcagaggagggcagcagtgtcatattgcgctgtgaaatttcc aaacctggaatacctgtagaatggaggaaaggacacgagctgctgaagaatggggtcaag taccagataaggaaaagggataccacctcggagctcctgatatggaaacctgtgcccgag gacggtggggtctacagctgcgtgtgtgccgatcagacgacatctgccactgtcaaaatc acagctctcccagtcaccttcaagcagaaactgaggaacgtgctgatcgaggagggcaac acggcagcgctacgctgtgagctgtctaaacctagtcacattgtggagtggaggaaacga ggaaatgaactcatcaggaatggagagaaatatcacatgcggcagagagacatgcttatt gaactgaggattttggatgtgacacctgatgacagcaatatctacacatgcatctgtgga aacatagagaccaccgctactctaactgtgaatgctcttcccgtcaccttcaagcaaaag ctgaagaaccttcaagttgcggaaggacacaacatcacgctgtcctgtgagatatctaaa cctggtgtcccggtagagtggaggcttggaggagatccgctggagaatggagagaagtac cagataaaacaaaaggactcagccctggaattgatcatcagagatgctgtagtagaggac agcggtgtctacatctgtgtgtgtagagagcagaggacaaaggccactgttaaaattatc gcggttcctgccacgtttaaagtgagcctgaagagccaggaaggcgaagaaggtaacagc gtgacattacattgtgagctgtcaaaggtgggagtccccgttcagtggcagaaagagggt caggtgctttctgaggaggtgtctcggggaaagtaccagatgaagctcgaacgaaagaca gctctgatgaccattatcaatatccaaccagaagatgcagggaagtacagctgcatcaca ggagacgagaaaacgaccgccgaggtcaaagtgaaaccactgcccattacatttaaacgg gagctccagtgcctggttgtgaaggaaggggacagtggcgttttctgctgcgagctctcc aaacctggagctcccgtcggctggaggaagggcagagtcctcctgaagcctggagagaaa tatgaaatgaaacaggacggacgcctcactaaactgatcatcagtgacgtggaggagagc gatgctggcaaatacacctgcaagactaaagacagccaatcaactgctgagctcactgtc aaaggtctaccacctagtttcaagcttctgctggttgaccaggaggtaacggagggcaac agtgtggtcctgcgctgtgagctcaacaaacctgctcagtcagtggagtggaggaaggga ggagagctgctgaagaatggagacaaattccagatgaggaagaaggacctgcaggtggag atgaaggtttcagagctcagtatggaggacgctggagattatacttgtatatgcggagaa cagaaaacaacagctaagatcagggtgaatgaacagcccattaaattcctccaagaactg aagaacattcaggtgcaagagggcaatggggtgacacttggctgtgagctctccaaacct ggaggcccggtggagtggaggaagggagacaatgtgttgaccagtggagagaaataccag gtgaagcagagcggctccatgctagagctcttcattaggaaaagcctccctgatgacagt ggctcctacagctgtgtttgtgacgacatcaaaactatggcaactgtcattattactgca atcccagtgactttcaagcaaaaattgaagaaccaggaagctgtggaggaaggttacgtg acgctgcgctgtgagctttctaaatcaggagttccggtggagtggaggagagatgctcaa ctcttgaaggagggagaaaaatatctaatgaagcaagagggccgggtggctgagatactg attacaaatgtaactctcgcagatgcaggggagtacagctgtttggttggaaatgttgtg acctcagctgacatcaaagtcagagcacttcctgtaacatttaagcaagaagtggagaat ttggaggtgaaggaaggggacagtggagcgttctgctgcgagctctccaaacctggagct cctgtggactggaggaaaggcagagttgtcctgaaacctggttacaaatatgagatgaaa caggaggggcatctcactaaactgatcatcaacaatgttgaagagagcgatgctggcaaa tacacctgcaagactaaagacagccaatcaactgctgagcttacagtcaaagctccgcct gtcacattcaatgcaaagttaaggaaccagcaggtggaggaggagaacagtgtgactttg tgctgcgagctgtccaagcccggcctcatggtagagtggaggagaggagaagagctgctg aagaacaatatcaagtaccagattaaaaatcgaaacagcagcctggagttgaccatcaaa aacacacaggtggaggacagcggcgtctacagctgtagctacggtgatgccaagacctca gccaatgtcacaattacacctattcccttcacttttaaaatgggcctgaagaaccaggag gcccctgaaggaggtaatgtgttcctgcactgcgagctgtccagggctggggtgcctgtg cagtggtggaagggggaggaccagctctatcagggaggaagatatcagatgacactgaaa gggaagatagctgagatgaccatcagaaacatccagccagaggatgttggagagtacagc tgcatcttcggggagcagaagacgacagcagaagttaacgtcagagcggcagcgtcggta ttctttgagaaggaactggagagccaagctataatggaggggaagtcagtgctgctgtct tgtgaggtttccagtgctaatgtccccgtcacttggaagaaggacaacactgtggtggag gaaggtggatgttacattgtcaagaagaaaggtcccacacacactctggagatcaagaaa cttcagctggaggatgctggagagtactgctgtatcaccagaggcaagaagaccaccgcc aagctgattgtgagggagcgcgttcggattgttacagagctacacgatgtaacagtgaca gcgggagaggacgcagtgtttgtgtgtgagctgagtcacgcagacgtgagtgagggcgtc tggtggctcggtcccagccctctgcagaagaacgagatgaaccagatgacatgccatggt ttccagcaccaactggtcctcaccatgacaacacctgaggagacgggcactgtggcgttt gtggttggggaggagaggacctctgcatgtctgctggttgttcctaaacccaaagtacta tttgaggagaccccaaaagacactgtggtcatggagggagagacggctactctgcgctgc accacctctgacttcaccaccctggttacctggaggcgcaaccatattccccttcgaaat ggtgataaatatgagatgcgtaaggagggaaaaatcaacctgctgctcatccctgatgca gagccccttgatactggcatatactcctgtgatacaggagatgtgcagagcagtgccaaa ctgactgtaacagagcttcctcccttcttccaggaggagttgcagagtgtggaagctgaa gagggatgcacagcctccttgtactgtgagctgtctaaacttggagtgccaattcaatgg aggaagaaccggcagccactgagagccagcaggacgtacgagatgaggcaggacggctgc ttcctccagctccacatcaaggacctcaaacttgaggacagtggcagctactcatgtcaa gcaggaagcgcagagaccactgctaccgtgtctgtgaaagagctcccaccattcttcaat aaagaattaagaagtgtggagggagaggagggagatgcagcctccctgcagtgcgagctg tctaaaccgcgggtgtccgtgcagtggaagaagaacagactacctctgagaaacagcagg aagtatgagatgaaacaagatggctgcttcctccagctactcatcaaagagctcgaacct gaagacagtggcagctacacatgtcaagcaggaaatgcggaaacaactgccaatgtttca gtgaaagagctcccaccatttttcaaaaaggaactgctgaacatgaaggctgtggaggga ggtacagcctccctgtgctgtgaggtgtccaaacctggagtgtcagtacagtggaagaag aacaagcagccactgagagccagcaggaagtatgagatgaagcaggatggctgcttccta cagctcaacatgaaggggctcacacctgaggacagtggcagctacacatgtcaaacagga agtgcagagaccactgcaaccttgtcagtgaaagaactcccaccatgtttcatagaagag ttacaaggtacagaggccgaggagggaggtacagcctccctgtactgtgagctgtccaag cctggggtgtcagtacagtggaagaagaacaagctgccactgagagccagcaggaagtat gagatgaagcaggatggctgcttcctccagctccacatcaaagatctcaaacctgaggac agaggcagctacacatgtcaagcaggagctgcagagaccactgctactttgaaagtgaca gagctcccaccattcttcaaggtcgacttgaaaagtgtggacattgaggagggaggtaca gcctccctgtcctgtgaagtatccaagcctggggtgtcagtacagtggaaaaagaacaag ctgccactgagagccaacaggaagtatgagatgaaacagaatgactgcttcctccagatc tacatcaatgatctcaaacctgaggacagtggcagctactcgtgtcaagcaggagctgca gagactactgcaattgtgacagtgaaagagctccctccagtcttcaagaaagacttagtc agtgtggaaactgaggagggaggtacagcctccctgacctgtgaactgtccaagcctggg gtgtcagtacagtggaagaagaacaagctgccactgagagccaacaggaagtatgagatg aagcaggatggctgcttcctccagctgcacatcaaggagctcaaacctgaggacagtggc agctacacatgtcaagcaggaagtgcaaagactactgctactgtggcagtgacagagctt ccaccattcttcaaagaagacttgcaaagtgtggaggctgatgaaggatgcccagcctcc ctgtgctgtgaattgtcaaagcctggagtgccggtgcaatggaagaagaatatgctgcct gtgagagcaaatacaaagtatgagatgaagcaggatggatgcctcctgcagctcaacatc aatgagctcaaacctgaggacagtggcagctacacatgccaagcaggagctgcagagacc actgctactctaacagtaaaagagctcgctccattcttcagcaaagaattacagactgtg gaggctgaggcaggaggtacagcctccctgtactgtaagctgtctaaacctggagtgtct gtacagtggaagaagaacaagctgccactgagagccagcaggaagtatgagatgaagcag gatggctgcttcctccagctccacatcaaagatctcaaacctgaagacattgacagctac 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cagggcgaccatgcgaataaacaagtgtccacacaggcagcgaaaaagccactgaaacta gtgccttctgtaaatcagcaggacaatcagtcagtagaacaaccaggaaagcctgtggaa aaagaagctgaatttgtccttccaaagccaccagtaaggactaaaagcaaatccaaaggg ggaatagaaaaacaagtatcaagagacacagagacagatcaagatgagcaacagccagca agaagtgtcataaaaacgaatgaggagcatccaataaaacaatcaataaagctattgaaa aaagagtctgaagagaaaccaacacttcagaggaaccagtcagtaacatcggacagtgaa atagttgagaaaattaaacagcctgccagagctgcagagaaagaaagcaaacagccaata aatcagccagttaaacctatgagaaaagagcctggaaatgaccaggaaattaaactggca gtggagccagtgagaagagagaaagaacaactaacaacaaaggtggcagaggacatccct ctcctctacatttctgaggatgaaacattcttggaggctttgaccgagataccagctaac cacagcaatgtgcagcccattgtctctttagttgtagggcctacaacagagctgcccctc cagaggacacaggcatccaaggattctctgccagacattgacatccacactgaagatgaa ccagagatgcaagaggctgcagtcaagatccaggctgctttcaaaggctacaaaacccgc agggacatgcgaccagtatttaaagaggtgtttaagaaccagagtgcagatcttcatagt actctcactctagtgtgcattgtagagggaaaacccagcacagtacgctggctgaaaaac ggccaagaaatcagtcatgaccatcggtgccgcattaagactgcagagactggagaatgc acactggtgatcaaaaacctggttaacagtgacagtggaatttatacctgtgaggtggtg aataagtttggtgtgacatcctacaatggaaacataacagtagaacagactgcacaacct actgctgcagtccagaaccctgtacaccctccccttgcagccataactcctttgcagctc gcttctccaaagcctgaacctcaggacaaatcacagagtcaagatctgcctgagagtcaa gcagtggtgcacacttcagctgcagatgctgaaaactatgtagaaagtatgagtgtctct ctgtgggagacctacaacctgacggagcaggacacccacatgagcctgcaggagagaaga cgatcctcactcattgctgccagctccatgtcaagtccttctgattatgacacagctcca gatataatggaacctgttgagactgctgcagtcataccaagggttgtaccaaaaccagta gaagaagttgctccaaaggaggataacaaagagataactgctccacaacctcctaagaaa ctgttgaaggtcaaagggactcatgacagtaaaatgaggacaccatctccaaagcaccat caggcccacacacccttagctagtactgtatctggattagagtcagagggggaggaggac agaagagagacatttgaaatgtacgtggctcgagctgactgcagtcccaacagtggcaac aaggacagttttgttctgaaggagggccagtttgtagaggtcctggactctgttcatcct gacagatggctggtgaggaccaaacccaccaaaactaaccctgctcggcagggatggctg tgtcctgcctacctagagaagaagagaaaggaggccttcccgcagctgagagcacctcaa gatgatcttgatggaatcggatctacaggagaggagtacaggagagctatgagtcaactg atccaaggcctgatcgatggagaggaggagtttgtaaaggagatgaagatgttcatatct caccagctaaattttctggactccagctgccacgtccccattaacatcctcaaccagaag gagatcattttcaggaatatcaaggacattgtgttcttacatgagtggtccatccttccc ggtctgagagaatgtgccacagatgatgatgtagccatgcatctgaccaaacacattgag tactttgagaagtatcttcactacatggtgggacaagcacaagcagaggcctgcatcact gagaaggctgcccaacagtatttcaaagagttaattgaacctggaaagcctgacgttcct gttatggatttcctcactttcctgcagcaaccagtagagaggattcaaacctaccaggcc ttactgaaggagttaattaaaaacaaagctaaaagtggccagagctgctttctgttagag gatgccttctctgtggtctcctgcctcccttggagatctgataacctgcaccaggtgtcc ctcatcgagaactacccaactcctcttactgccttgggtgagcccgtgcgacagggagtc ttcactgtgtgggaggaatctccagaaattaagacggccactagagggcatcagagacag gtctttctctttaaggaatgtattgtactgtgcaagctgaaaaaagacaccagcatgaac agagacacctacaccttcaggaacaaaatgaagctgaatgatgtgcaaataaaggagact gtgggtggagaggaaaggtcctggggtttgtggcacgagcacaggggctccatgaggagg tacacactacagggccactccacactggttaaactctcctggctcaaagacctgaaggag ctccagcaacgctccagcacgctcactaacagccctccagtgttcgagtcattgttgtct gactgcaaaacaaagataggacagacgatcaaactgacctgtaaggtctcaggatctcca actccagttatcagctggctcaaagatggtcttccgttggaggatgacccgcgtcacatc atcaccgcagaccggttaggcacttgtagtctgatcctggacagcctcactgcagaggac tccggacagtatgcgtgctacgcctgcagctccatgggcagtgctggctctctggctaag gttgtggtgcaggctccacccaggtttgtgagtcgcctggagagtgcctgtctgatagaa ggagaggatatccagttctcctgctccacactcactacccctttaccacgaattaggtgg ttgaaagatggcagagagttgaccgaccagcagaaatattccatcgttaatgaccctcgg agtgggatcttgtctctgacagtcatcagggcaacagaggcagatattggacagtatgag tctgagctttggaatgaactgggctgcgtcaagtgcaaggcaggtctatgtcccgcctat gtacctccgactgacatcgggaatgatcaaccgcaggacttgcctcctaaagatgctgac tcagagggctggtccactgccttcgtgaagaaatggttgcagactgatttcagccccact tctattgccaagatgctttttcctcctggatccactgaacaggctgagtgtagcactgaa gtggatgttcatgcctcaacggatcaggcagcacagcagcctctgtgttacctagaagaa gaagaggagatctacatctcagagcagatgcaggaaattactgatgctcctcccttcatc caggtacctgctgaggacctgtatgtagagccgggtcagacatctacatttactgccatc atcacaggaagacctactcctaagatacagtggtacaaggatggagaagagcttgcagcc aatgaaaatgtgaagatagtgcaacagggtgcccggtgctcagtgaccattgtgtgcccc gacggtgaggacagtggcatatacacctgttttgctcacaatgactctggtcatgcctcg tgtcaggctcagctcacagtggaggaaggtccactggagtctcaggagagagaagtggag ctggggaagagaaggaagttgttctctgtctatgacgtacatgaggaaattggaagggga acatttggagtcgtgaagcatgtagtccacagacggacaggggaagtctttgctgccaag tttcttcctcttcggagcaacactcagacccgggccttccaggagagggacttgctatcc cgtctcgctcacccaagagtggcctgtctgctggatttcttttgcaccagacgcacgctt gtgctaatcacagaaatctgctgttctcatggacttctggaccatttattactgagagga tcagtctcagaaaaagaggttcagacatatatccagcaacttcttgaaggagttagtcac atccacagcttgaacatcttgcatctggacattaaacctgataatatcctaatggtgtac ccaccaagagacgagatcaagatctgtgactttggcttctgccaggaaatcgacacatcc cgacaccagtacagcatgtttggtacacctgagtttgttgcaccggaaatcgttcaccag gaaccagtcacagtggccaccgatatttgggctgtgggtgttatagcctatctgtgtctg gtgtgccgatgcccctttgtgggtgagactgaccgagctacgctgctgagggtgggggag gggaccctgaactgggatgcccctgatgtcctgtacaggagccctgaagccaagaacttt ctccacatggtccttcagccagatccagagaagcgaccgtctgcctttgagtgcttgagt caggaatggttccaggatgaacatgcgggagaagatactgatgaaatcaacacaaagagt ttgaaagtcttcatctcaaaaaggaaatggcagcgttctctgacctgcattggttcagtg ctcacgttgaggcccattcctgaactgctggatgctcctctcagagatactgcagtgacg gtgccccgtgagcaccaggatcacagcagcagctccccgagcagtggctcctcgtctgag tatgacgaggctgactcttgggactttttccagcactgcagccagactgaggaggaagag gaaacagaggaagactttgattctttgatggagagagcacggatccctgagccttttgcc aaactgcacctagatggagaggaggaagaggagctaacattaggggaggaagaggatggg gagatagtaggaaggaggagtgtactgcagcggagtatgagcaggcagtcagttgcatca tcagaagtatcgtcccaacacacacctcagagagagcgtcggtttagcaaggacagtagt ccatccctctacctttctgatggggacgacggttcagagagtgatggaggtcgtatccct cgagggagcgtcatccgaagcactttctataacacctctcatcagctttcaccaatgtct gccagacacatgacattaagggacaaattccaggccaaaaagcaggagagaggccgcaag cctctcaggaggagcttctcaggtcgcctcaacgaacctctgattgaatatgtggaggat gaaacagagactaaccgtggtcagagacggggatctgtccagcccaccatgcagaagtcc tgctcgtttgacagtggagttggccttatccacggcaacatacctcctcacaggagaagc aggtctcttgatgaatattcacgacgatctcccagctcacccagcagggcaatgccaggt gaggaggaaggctctcagagtctgaaggaagatttcacagacgatgaagtggcagggaga aacttattggccatcctgagctctcagcgagccacaaggagaagaggctctgttgctcct gtacaagggactcacacatcaagtggatcatctggtgcctctgacttcctcgctggagac agaaggagctccatgctggatcgtgagcagacggtgggagatacctttgtcggctcccaa gggtcactggctgagtcatttattttggagcatggtggctctgagtcttcaagtagactg gggtcctatgaggagttgagtcatggtcatctcagaggaggatacagatcaggggagagt gaaggatatgatgatcagggtgagcctctgattccaccatcaccgtgctcattccaagag gtaaaacccaaaggctcggttcctcaggcaccgccaaggaaccgcacgcgatccaatccc aacttatccacaaacaacagaggtcagccggggacgccagtgatgccgagacccagtccc agcctctcttctctacaggctccagagaggccccccagaaccaaggataagaaagagggc tctggtctccagaggcatgcatccgctccagccctcgaagtccgaccacccacagggaag tcacccaagctgggactgctgaagatcttccgcaggcagtcctggactggccattcctac tcgcagctagatgacacagagttaggacccacactaggagagatcatgaagcccaacaca cccaccatgtctttgaggaagaaaatgagagcttcagcctccagcctgaccaagctgttc tccaggtcctccagtaaggaggatgtgagtaaaggagggccaatagtgaaaggatcagct tccaccccacctgagagtcctaaaaagagaacctcaaaactcttgccatctttcaaaata cctgcgttcaaaaagtcaaaagatctgccagtccgtccctgcaaggccgaggtgttccag ttagacggaggtggagtcctgctggtgtggaggccggttcagtccagtgatcctgtcact tactgtgtgcagtactgtacagacggtggggagtggaccgtactgtccgaggaggtgaca gagagctgctatgtggtgagggatttaaccagaggagcctcgtacgtcttcagggtgggt tgcatctccaagacaggagcaggacctttcagcgatgcttcagctccagttgtcatggcc tctcatcctgaagagattcacatccctctcattcagactgagtcactggggtcaaaggtc accggatcacactcacacacaaaacacaagagctacagcttcctctctgagatcaacagg ggtcgtttcagcgtagtaaacttgtgtcgggatgttgagaccagccaagtgtttgcttcc aagatctccccttaccaggcggagcagagacctctggtgctgcgggagtaccagttgctg aagaagcttcatcaccctcacctggttcagctgcacgccgcgttcatcgccccccgctac ctggtgttagtggaagagctctgtcccggcaaggagctgctctacggtcttgctgcgaga gatcagtatgcagagactcacgtcgcagagctgctggttcaggtcctcagtgcagtcgac tatcttcacagccggcgagtgatccacctggacctgaagtctgacaacatgctggtggac gaccgtaaccacctgaagatcgttgactttggctcggctcagtccttcacgcctggacag cctctcaacgtcgagcacatccacggcctgtcagacagcagagactgccgcagcaaagtt tatattgtccttcctaaagctccggagatccttgaaggtcagggtgtcgggccggagaca gacgtttgggctgttggagttctgtcattcatcatgttgagtgccgacagcccatttcat gcggagctcagctgggagcaagacagaaacatcaagaaagggaagatccagtttggacgg tgttaccccggtctgtcagagggagccttaaacttcatgaagagcagcctgaacaacaaa tcctgggggaggcccactgcagcagagtgtctccagaacccatggatccgcgcccatcgc gccccacacaaagcccgacactccaaagtgtgtttctccactgacaagcttaaagattac ctcaagcagaaagaggagaaacgagatcaggtgcgcaccaagcttcagcctcccttcttc cagtaa

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