Bufo gargarizans (Asiatic toad): 122934358
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Entry
122934358 CDS
T07965
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
bgar
Bufo gargarizans (Asiatic toad)
Pathway
bgar00270
Cysteine and methionine metabolism
bgar00480
Glutathione metabolism
bgar01100
Metabolic pathways
bgar01240
Biosynthesis of cofactors
bgar04216
Ferroptosis
Module
bgar_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
bgar00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
122934358 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
122934358 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
122934358 (GCLC)
Enzymes [BR:
bgar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
122934358 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
122934358
NCBI-ProteinID:
XP_044145692
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All DBs
Position
4
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AA seq
632 aa
AA seq
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MGLLSQGSPLSWEETKKHADHVRQHGIIQFLNIYHKLKERQKDVLKWGDEVEYILVAFDH
EKHKVRLVLNGEEMLDTLQGRGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEASSLLSDYVSICTITSFPRLGCPGFTFPEFQPTPVEQGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGDKVAINVPIFRDQNTPTPFIERFANDPGDEGKAALPDHIYMD
AMGFGMGNCCLQVTFQACSISEARCLYDQLATICPIVMALSAAAPFYRGYVSDIDCRWGV
ISASVDDRTKEERGLEPLKNDKYRISKSRYDSIDSYLSTCGEKYNDIDLTIDKEIYSQLT
REGIDHLLAQHIAHLFIRDPLTLFEEKIDLDDSNESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RKGMFYFRKDICKASIAPVDGCCTAVNGTEAEEYTLMSIDTIINGKDGVFPGLLPILNSY
LENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFVSNHPDYKQDSVITDRINYDL
IVKCNQIANEQASCPELLGFSTRVKQSGNKYV
NT seq
1899 nt
NT seq
+upstream
nt +downstream
nt
atgggtctcctgtctcagggctccccgctcagctgggaggaaaccaagaagcacgcggac
catgtgcggcagcacggcatcatccagttcttaaacatttaccacaaactgaaggagcgc
cagaaggacgtgctgaagtggggcgatgaggtggagtacattttggttgcctttgatcat
gaaaagcacaaggtacgattagtgcttaacggagaagaaatgcttgatacacttcaaggc
cgaggtgaaaaaataaacccaaaccatcctactctttggagacctgagtatggaagctat
atgattgaggggactcctggccagccctacggtggaacaatgtccgaatttaacacagtg
gaagataatatgaggaaacgacgccaggaagcctcttctttgctttcagactacgtctca
atttgcacaataacttcctttccgagattgggatgtcctggatttacctttccagaattt
caaccaactccagtggaacaaggagcctccaagtctctcttctttccagatgaagcgatt
aacaagcaccctcggtttagtactttaaccagaaatattcgacacaggcgtggtgataaa
gtagccataaatgttccaatttttagagaccaaaatactcccacaccatttattgaaaga
tttgcaaatgatcctggtgacgaaggaaaagcagcattacctgatcatatatacatggat
gccatgggttttgggatgggcaactgctgtcttcaggtaactttccaggcgtgcagcatt
tcagaagccagatgtctttatgaccagctagcaacaatatgcccaattgtaatggcttta
agtgctgctgctccattctacagaggctatgtatctgatattgactgccggtggggcgtt
atatctgcctctgtagatgatcgcactaaagaagaacggggcctggagcctttaaaaaat
gacaaatatcgaatcagtaaatctcggtatgattctatagacagttatctgtctacatgt
ggtgaaaagtacaatgatattgacttaactatagataaagaaatctatagccagctaaca
agagaagggattgaccatctcttggctcaacacatcgcacatctatttatccgagatcct
ttgaccttgtttgaagagaaaatagatctggacgactccaatgaatctgatcattttgag
aatattcagtcgacaaattggcagactatgaggtttaagccacctccgcccaactcggat
ataggttggagagtggagtttcgtcctatggaggttcagttgacagattttgagaactct
gcatatgtagtgtttgtggttttactgacgagagtaattctttcatacaagttggatttt
ctaattcctttgtcaaaggttgatgaaaacatgaaagtggcccaaaaaagagatgctgtt
aggaaaggcatgttttacttcagaaaggatatttgtaaagctagtatagctcctgttgat
ggttgctgcacagcagttaatgggacagaagctgaagaatacactctaatgagcattgat
acaataatcaatggaaaggatggtgtgttcccaggtttattaccaattctcaattcctac
cttgaaaatatggaggttgatgtagatactcgctgcaccatcttaaactaccttaaactt
atcaagaagagagcgtctggagagctgatgaccgttgcccgatggatgagagaatttgta
tcaaatcatccggattacaagcaagacagcgtgatcactgacagaattaattatgacctg
atagtgaaatgcaatcaaatagctaatgaacaggcgagctgtccagagctgctggggttt
tcaactagagtaaagcaaagtgggaacaaatatgtatga
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