KEGG   Bufo gargarizans (Asiatic toad): 122936263
Entry
122936263         CDS       T07965                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bgar  Bufo gargarizans (Asiatic toad)
Pathway
bgar00562  Inositol phosphate metabolism
bgar01100  Metabolic pathways
bgar04020  Calcium signaling pathway
bgar04070  Phosphatidylinositol signaling system
bgar04081  Hormone signaling
bgar04082  Neuroactive ligand signaling
bgar04261  Adrenergic signaling in cardiomyocytes
bgar04270  Vascular smooth muscle contraction
bgar04310  Wnt signaling pathway
bgar04371  Apelin signaling pathway
bgar04540  Gap junction
bgar04621  NOD-like receptor signaling pathway
bgar04912  GnRH signaling pathway
bgar04916  Melanogenesis
Module
bgar_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bgar00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122936263 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    122936263 (PLCB1)
   04371 Apelin signaling pathway
    122936263 (PLCB1)
   04020 Calcium signaling pathway
    122936263 (PLCB1)
   04070 Phosphatidylinositol signaling system
    122936263 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    122936263 (PLCB1)
   04081 Hormone signaling
    122936263 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    122936263 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    122936263 (PLCB1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122936263 (PLCB1)
   04916 Melanogenesis
    122936263 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122936263 (PLCB1)
   04270 Vascular smooth muscle contraction
    122936263 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bgar04131]
    122936263 (PLCB1)
Enzymes [BR:bgar01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     122936263 (PLCB1)
Membrane trafficking [BR:bgar04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    122936263 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    122936263 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 122936263
NCBI-ProteinID: XP_044148313
LinkDB
Position
4:460031363..460914346
AA seq 1225 aa
MAGAQPGVHALQLKRVCVSDTLKRGSKCIKWDDDSNLVYPVVLKMDPNGFFLHWVDQNKE
TELLDISLVKDARWGKHARTPKDPKLKEQLEVGNFGGRLEYRMFTIVYGPDLVNISYLNL
VAFQEEIAKEWTDEIFSLATNLLAQNMSRDAFLEKAYTKLKLQANQEGKIPVKNIYRIFS
ADRKRVETALESCNLPSGRSDSIPQDDFTPELYRVFLNNLCPRPEIDNIFSEIGTKSKPY
LTVDQMTEFINSKQRDPRLNEILYPPLKQGQVQLLIEKYEPSSSLASKGQLSVEGFIRYL
NGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLAGCRC
VELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPYPILLSFENHVDSPK
QQAKMAEYCKQIFGDGLLTEPLEKYQLEPGVPLPSPMELKYKILVKNKKKSHKSADGSGK
KKLSEQASNACSDSSSVFEPSSPGAGEADIESEEDDDDDEDDCKKSSMEEGTAGNEASAT
EEMSNLVNYIQPVKFESFEISKKRNKSYEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRI
YPKGTRVDSSNYMPQVFWNAGCQMVALNFQTIDFPMQLNMGMYEYNAKCGYRLKPEFMRR
PDKHFDPFTETTVDGIVANTVSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKT
SQGNAVNPVWEEEPIVFKKVVLPSLACLRISAYEEGGKFIGHRILPVYAIRPGYHYICLR
NEKNVPLTLPAIFVCIEVKDYVPDTFADVIEALSNPIKYVNLMEQRSRQLAALTLEDEEE
VKKEAEAGDAPSETNSEPRPAPAENGLNHASTLTPKPASQSVHSQPAPGSVKVPAKTAPA
EDLIMSVLTEVEAQTIDELKQQKSFVKLQKKHYKEMKDLVKKHHKKTTDLIKEHTTKYNE
IQNDYLRRRAILEKTARRDSKKKGESGSPDHNSSTVEQDLAALDAEMAQKLVELKEQQQQ
QLLNLRQEQYYSEKYQKREHIKQLIQKLTDVAEECQNNQLKKLKETCEKEKKELKKKMDK
KRQEKVTETKSKDKNQMEEEKTEMIRSYIQEVVHCLKRLEDAQTKRQEKLIEKHKEIRQQ
ILDEKPKVELDQEYQDKFKRLPMEIQEFVQEAMKGKFSEEREHSSSLLTPDSGKSPVGNS
GNHKSLDHEEEGEEEAPAKAFDTSL
NT seq 3678 nt   +upstreamnt  +downstreamnt
atggcaggggcacagccaggggtacatgctctgcagctcaaacgtgtctgcgtctctgac
accctgaaaagaggatccaagtgcattaagtgggatgatgactcgaatcttgtgtatcct
gttgttctcaaaatggatcctaatggatttttcctgcactgggtggatcagaacaaggag
actgaactattggatataagtttggtgaaagatgccagatggggaaagcatgcacgaact
ccaaaggacccaaagctgaaggagcagttggaagtcggaaactttggaggtcgattagaa
tatcggatgtttaccattgtgtacggcccagatctggttaacatttcatatctgaattta
gtagcatttcaagaagaaattgcaaaggaatggacagatgagattttcagtctggcaaca
aatttgttggcacagaacatgtcccgggatgcatttctggaaaaagcatacaccaagctg
aagcttcaagccaatcaagaagggaaaattcctgttaaaaacatataccgtatattctcc
gcagacagaaaacgagtggaaactgcattagagtcttgtaatcttccatctggcagaagt
gattccatccctcaagatgactttacaccagaattgtacagagtcttcttaaataacctg
tgtccccgacctgagatagacaacattttctcagagattggcacaaaaagtaaaccatac
ctcactgttgaccagatgacagaattcattaactccaagcagcgggatccaaggctaaat
gaaattctgtatccacctctgaagcagggacaagtccagctgctaattgagaaatatgag
cctagcagcagcttggcatcaaaaggtcagctttcagttgaaggattcatacgatatctc
aatggagaagaaaatggagttgttccacctgagaaactggatttaaatgaagatatgtct
caacccctctctcattattttattaattcctcacacaacacttacctcacagctgggcag
ctggcaggtaactcctcggtagagatgtatcgccaagtgctgttagctggatgccgttgt
gtagaattggattgctggaaggggcgtaccgcagaggaggagccggtgatcacacatggg
tttaccatgaccactgaaatatcttttaaggaagtcatagaagcaattgctgaatgtgca
tttaagacctcaccgtacccgatcctcctgtcctttgaaaatcacgtggactcgccaaaa
caacaggccaagatggctgaatactgcaagcaaatttttggggatggacttttaacagaa
ccattggagaagtatcaacttgaaccaggggtccctcttcctagtcctatggaactgaag
tataaaattcttgtgaaaaataaaaagaaatcgcacaaatcagctgatggaagtggaaag
aagaaactctcagaacaagcgtccaatgcttgcagcgactcttctagtgtatttgagcca
tcatcgcctggcgcaggtgaagccgacattgagagtgaggaagatgatgatgatgatgag
gatgactgtaagaaatcttccatggaagaaggcaccgctggaaatgaagccagtgccaca
gaggagatgtccaacctggtgaactatattcagccggtgaagtttgagtcttttgagatt
tctaaaaagagaaacaagagctatgaaatgtcctccttcgtggaaaccaaggggcttgag
cagctgacaaaatctcctgtagagtttgtagaatataacaaaatgcagcttagtagaatt
tatccaaaaggaacccgagtagattcatccaactatatgcctcaggtcttttggaatgcg
ggatgtcaaatggtagctcttaacttccaaacaatagattttcctatgcaacttaatatg
gggatgtatgaatataatgctaaatgtggatacagactgaagcctgagttcatgagaagg
ccagataaacattttgatccttttactgagacaacagtagatgggatagttgcaaacaca
gtgtctgtaaagatcatttcaggacagtttttgtcagataagaaggttggcacctatgta
gaagtggatatgttcgggttgccagttgataccagaagaaaagcgttcaaaacaaagaca
tcacaaggcaatgcggtgaatcccgtatgggaggaggagcctattgtttttaaaaaggtt
gtgcttccctcccttgcatgtctaagaatatcggcatatgaagaaggagggaaattcata
ggtcaccggatattacccgtttatgcaatccgtccaggttatcactatatctgcctgaga
aatgagaaaaatgtgccactcactctaccagcaatctttgtctgcatagaagtgaaggat
tacgtccccgacacattcgcagatgtgattgaagctttgtcaaatccaattaaatatgtc
aatttgatggaacaaagatccagacagctggctgcactcacgctggaagacgaagaagaa
gtgaagaaagaggcagaagccggtgatgctccatcagaaactaacagtgaaccaaggccg
gcaccagcagaaaatggcctgaaccatgcttctacactaacaccgaagccagcatcccag
tctgttcacagtcagccagctccaggttctgtaaaagttcctgctaaaactgcacctgct
gaggacctcataatgagtgttttaacagaagtggaagctcagaccatcgacgaactgaaa
cagcaaaagtcctttgttaaattgcagaagaaacattacaaggaaatgaaggatcttgta
aaaaagcaccataagaaaaccacggaccttatcaaggagcacaccactaagtataatgaa
attcagaacgattacttaaggaggcgggcaatcctggaaaagacagccagaagagacagc
aaaaaaaagggcgaatctgggagtccggatcataattcctctactgtagaacaagattta
gccgcattagatgcagaaatggcacagaaattagtagagctgaaagaacagcagcaacag
cagcttctcaatctccgacaagaacagtattacagcgagaaatatcagaaaagagagcat
atcaaacagctcatccagaagctgacagatgtggccgaggagtgccagaacaaccagctg
aaaaagctcaaggaaacatgtgaaaaagaaaagaaagagttaaaaaagaagatggacaag
aaacggcaagaaaaagtcacagaaaccaaatcaaaagataagaatcaaatggaggaggag
aagacagaaatgatcagatcctatatccaggaagtggtgcattgccttaaaaggttggaa
gatgctcaaaccaaaaggcaggaaaaacttatagagaagcacaaggagattcgacagcaa
atattggacgaaaagccaaaggttgaacttgatcaggaataccaggacaaattcaagcga
cttccaatggaaattcaagagtttgtccaggaggccatgaagggaaaattcagtgaagaa
agagaacatagctcttctctcctaacacccgacagtgggaagtctccagtggggaactcg
ggaaatcacaaaagtctggatcatgaagaagaaggtgaagaagaggctccagcaaaggca
tttgatacatcactctaa

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