Halalkalibacterium halodurans: BH2570
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Entry
BH2570 CDS
T00039
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bha
Halalkalibacterium halodurans
Pathway
bha00300
Lysine biosynthesis
bha00550
Peptidoglycan biosynthesis
bha01100
Metabolic pathways
bha01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bha00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BH2570 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BH2570 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BH2570 (murF)
Enzymes [BR:
bha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BH2570 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAB06289
UniProt:
Q9K9S5
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All DBs
Position
complement(2692376..2693734)
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AA seq
452 aa
AA seq
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MSISTQLLKGIITKNNPSAPLSFTGVSTDTRTIQEGNLFVPLIGERFDGHDYVEQALSKG
AQASLWATSVPVPESLKNEDRLLFVNDTLFALQAMAKAYLRQTEPTVVAVTGSNGKTTVK
DLLYATLAPLGSIYKTQGNYNNHIGLPLTVLSMPANCQTLILEMGMSGLGEIELLSKLAT
PDIAVVTNIGESHLEQLGSRENIAKAKMEIALGLKPTGVLFLDGDEPLLSHYVKEGVQTV
GFSSENKIVIHDLEAREDGYSFTIDEHSYDIKLIGEHNVKNAAYAVSVALHLGLSPEQVA
RSLERVAISKMRLEKIEGQKGALLLNDAYNASPTSMKAAIKTLKAYPNYEKKVAVLGDIY
ELGIDEEALHRSVADEITEPITTAVLVGEKGQWIADEMKRRGSNIPFVSFVEKEEATDYI
EGLLDGKTVVLFKASRGLELESIVDKLKREEG
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgagtatatcaacacagcttttaaaagggatcattacgaaaaacaacccatctgctcca
ctctcgtttaccggggtatcgaccgacacacgcacgattcaagaagggaacctttttgtt
ccgcttatcggtgagagatttgatggtcatgattatgtggaacaagcgctatctaaggga
gcacaagcttcactttgggctacttctgttccggtacctgagtcattaaaaaatgaggat
cgccttttgttcgtaaatgataccctatttgcgctacaagcgatggcaaaagcttatttg
cggcaaacagaaccaacagttgtagccgtaacgggaagcaatgggaaaacgacagtgaaa
gacttactctatgcgactcttgctccgttaggctctatttataaaacgcaagggaattac
aataatcatatcgggctgccgttaacggtgctttccatgccagctaattgtcaaacactc
attttagaaatggggatgagcgggttaggggaaattgaactgttaagtaaactagcaacc
ccggatattgctgtcgtaacgaacataggagaatctcaccttgaacagctagggagccgc
gagaacattgcaaaagcaaaaatggaaattgccctcggcttaaagccaacaggtgtccta
tttctcgacggtgatgaaccgttgctttctcattatgtgaaagaaggcgtgcaaacggtt
ggattttcttcggaaaataaaatcgtgattcacgatctagaagctcgtgaagatggctat
tcgttcaccattgatgaacattcttatgacatcaaactgattggtgagcataatgttaag
aatgcagcatacgctgtcagcgtagcgctacacctcggactttcaccggagcaagtcgct
agatcattagagcgtgtggcaatttcaaagatgcggcttgaaaagatcgaaggtcaaaag
ggagcccttcttttaaatgacgcctataatgctagtccgacttcaatgaaagcagcgatc
aagacgttaaaggcatatccgaactatgaaaagaaggttgctgttttaggagatatttac
gagctaggaatagatgaagaagcattgcatcgctcggttgccgatgaaataacagagccg
ataacgaccgcggtccttgttggggaaaaaggtcagtggatagcggatgagatgaagcga
agagggagcaatattcctttcgtttcgtttgttgagaaagaggaagcgacggactatatt
gaaggtttattagatggaaaaacagtcgttttattcaaagcctctcggggattggaattg
gaatcgattgtagataaattgaaacgggaggagggataa
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