Burkholderia humptydooensis FDAARGOS_899: I6G56_07065
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Entry
I6G56_07065 CDS
T08266
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bhg
Burkholderia humptydooensis FDAARGOS_899
Pathway
bhg00290
Valine, leucine and isoleucine biosynthesis
bhg00620
Pyruvate metabolism
bhg01100
Metabolic pathways
bhg01110
Biosynthesis of secondary metabolites
bhg01210
2-Oxocarboxylic acid metabolism
bhg01230
Biosynthesis of amino acids
Module
bhg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bhg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
I6G56_07065
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
I6G56_07065
Enzymes [BR:
bhg01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
I6G56_07065
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
WH_CYT4
Motif
Other DBs
NCBI-ProteinID:
QPS44843
UniProt:
A0A7U4ST19
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All DBs
Position
1:1230298..1231845
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AA seq
515 aa
AA seq
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MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMRVDVIEAGFAASSNGDFDAIHA
IASQVKDSTICSLARANDKDIQRAADALKPANSFRIHTFIATSPLHMEKKLRMTPDQVYE
QARLAVRFARKFTDNIEFSPEDGSRSDMDFLCRVLEAVIAEGATTINIADTVGYGVPELY
GNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNT
SLEEIVMAVKTRKDYFGLDLGIDTTQIVPASKLVSQITGFVVQPNKAVVGANAFAHASGI
HQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSEAELNAAFA
RFKDLADRKAEIFDEDIIAIVTEEESALAQEHEHYKFVSLAQRSETGERPQAKVVFAVDG
DEVAGEASGNGPVDATFNAIETEVGSGAELLLYSVNAITTGTQAQGEVTVRLSKSGRIVN
GVGTDPDIVAASAKAYIAALNKLHSNADKLNPQRA
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgacagacaagctgatcattttcgacacgacgttgcgcgacggcgagcaatcgcccggt
gcgtcgatgacgaaggaagagaaaatccgcatcgcgaagcacctcgagcgcatgagggtc
gacgtgatcgaagccggcttcgcggccagctcgaacggcgatttcgacgcgatccatgcg
atcgcgtcgcaagtgaaggacagcacgatctgctcgctcgcgcgcgcgaacgacaaggac
atccagcgcgcggcggatgcgctcaagcccgcgaacagcttccggatccacacgttcatc
gcgacgtcgccgctgcacatggagaagaagctgcggatgacgccggaccaggtgtacgag
caggcgcgcctcgcggtgcgcttcgcgcgcaagttcaccgacaacatcgaattctcgccg
gaagacggcagccgctcggacatggatttcctctgccgcgtgctcgaggctgtgatcgcc
gagggcgcgacgacgatcaacatcgcggacaccgtcggctacggcgtgccggaactgtac
ggcaacctcgtgaagacgctgcgcgagcgcatcccgaattcggacaaggcgatcttctcg
gtgcactgccacaacgatctggggatggcggtcgcgaactcgctcgccggcgtgaagatc
ggcggcgcgcgccaggtcgagtgcacgatcaacggcctcggcgagcgcgcgggcaacacg
tcgctcgaggaaatcgtgatggccgtgaagacccgcaaggactacttcggcctcgatctc
ggcatcgacacgacgcagatcgtgccggcgtcgaagctcgtgtcgcagatcacgggcttc
gtcgtgcagccgaacaaggcggtggtcggcgcgaacgcgttcgcgcacgcgtcgggcatc
caccaggacggcgtgctgaaggcgcgcgacacgtacgagatcatgcgcgcggaagatgtc
ggctggaccgcgaacaagatcgtgctcggcaagctgtcggggcgcaacgcgttcaagcag
cgcctgcaggagctcggcgtgtcgctcgacagcgaagccgagctgaacgcggcgttcgcg
cgcttcaaggatctcgccgaccgcaaggccgagatcttcgacgaggacatcatcgcgatc
gtcaccgaagaggaatcggcgctcgcgcaggagcacgagcactacaagttcgtgtcgctc
gcgcagcgctcggagacgggcgagcggccgcaggcgaaggtcgtgttcgccgtcgacggc
gatgaggtggcgggcgaggcgagcggcaacggtcccgtcgacgcgacgttcaacgcgatc
gagaccgaggtcggcagcggcgccgagctgctgctgtattcggtcaacgcgatcacgacg
ggcacgcaggcgcagggcgaggtgacggtgcgtctgtcgaagagcgggcggatcgtcaac
ggcgtcggcaccgatccggacatcgtcgccgcgtcggcgaaggcgtatatcgccgcgctc
aacaagctgcactcgaacgcagacaagctgaatccgcaacgcgcgtag
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