Brachyspira hyodysenteriae WA1: BHWA1_00736
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Entry
BHWA1_00736 CDS
T00865
Symbol
murfF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bhy
Brachyspira hyodysenteriae WA1
Pathway
bhy00300
Lysine biosynthesis
bhy00550
Peptidoglycan biosynthesis
bhy01100
Metabolic pathways
bhy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bhy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BHWA1_00736 (murfF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BHWA1_00736 (murfF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BHWA1_00736 (murfF)
Enzymes [BR:
bhy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BHWA1_00736 (murfF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
MurT_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACN83230
UniProt:
A0A3B6V9W4
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Position
complement(867879..869231)
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AA seq
450 aa
AA seq
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MGNTLLKDIIAVTKELNSKCFKNIEDLNLNKELEISTDSRDNFDENKLFLAIKGEKFDGN
KFALETYNKGCRYFILSDASIKLPDDAVVFYADDTILFFIKLAREYRRRFNIPVISITGS
CGKTTTKELTHLFLSTKYKALKTEGNLNNEIGVPKTIFNLDDSYEIAVIEAGMNHENELL
RISEAIEANTVIINNVEPVHIAYLGSIENIAYAKSELFNHTRENANAVINKNTNCIDILE
KEASRNNIKNIIEADIKEIIKKDDNTFEYNGITFKHNLIGDFNLHNVLSALKAAELYDVD
LQKCADILITYESQKNRMQIINIKGCNVINDCYNSNPAALKNMIKFLSQRSESKKIAVIG
DMLETETENSSYHKDIGKIINELKNIDTVIAVGKHSKDIYDTVNCEKYYFENAQSSVEKV
KEFLKYDTAMLIKASLGMGFAVIIDSIKNI
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgggtaatactttattaaaagatataattgcagtaacaaaagaattaaactctaaatgt
tttaaaaatatagaagatttaaatttaaataaagaattagaaatatcaactgacagcaga
gataattttgatgaaaataaattatttttagcaattaaaggcgaaaagtttgacggaaat
aaatttgcattagaaacttataataaaggatgcagatattttattttaagcgatgcaagt
ataaaacttccagatgatgcggtagttttttatgccgatgatacaatacttttctttata
aaactcgctagagaatatagaagaagattcaatatacctgtgatatcaataacaggaagt
tgcggaaaaaccactacaaaagaattaactcatctctttttatctacaaaatataaagca
ttgaaaacagaaggcaatttaaataatgaaataggagtgcctaaaacaatatttaattta
gatgatagttatgagatagcagttattgaagctggtatgaatcatgaaaatgaattgtta
agaatatctgaagctatagaggcaaatactgttataataaataatgtagagcctgtacat
attgcatatttaggttctatagaaaatattgcctatgctaaatcagagctttttaatcat
actagagaaaatgctaatgctgtaataaacaaaaatactaattgtattgatatattagaa
aaagaggctagtagaaacaatataaaaaatataatagaagctgatataaaagaaataata
aaaaaagatgataatacatttgagtataatggtataacttttaaacataatttaatcggc
gattttaatttgcataatgtattatcagcattaaaggcggctgaactttatgatgttgat
ttacagaaatgtgcggatattttgataacttatgaatctcaaaaaaacagaatgcaaata
atcaatataaaaggctgtaatgtaataaatgactgttacaattcaaatcctgctgcatta
aaaaatatgattaagtttttatctcaaagaagtgaatcaaaaaagattgctgtaataggt
gacatgcttgaaacagaaacagaaaattcaagctatcataaagatattggaaaaattata
aatgaattaaaaaacattgatactgttattgcagttggaaagcattcaaaggatatttac
gatacggttaattgcgagaaatattattttgaaaatgctcaaagttctgtagagaaagta
aaagagtttttgaaatatgatactgcaatgttaataaaagcttcattgggtatgggattc
gctgtgataatagattctataaaaaatatataa
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