KEGG   Bombus impatiens (common eastern bumble bee): 100744997
Entry
100744997         CDS       T04362                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
bim  Bombus impatiens (common eastern bumble bee)
Pathway
bim00562  Inositol phosphate metabolism
bim01100  Metabolic pathways
bim04070  Phosphatidylinositol signaling system
Module
bim_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bim00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100744997
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    100744997
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bim04131]
    100744997
Enzymes [BR:bim01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100744997
Membrane trafficking [BR:bim04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100744997
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100744997
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RA C2 EF-hand_like EF-hand_PLCG2 RasGEF DNA_pol3_tau_4
Other DBs
NCBI-GeneID: 100744997
NCBI-ProteinID: XP_012249436
UniProt: A0A6P6FIH9
LinkDB
Position
Unknown
AA seq 1695 aa
MEIVAGLKCHKLKPFWQSVNDPVPVLENLSSALLSPEYELALARSLAMPECPVVPFFGAF
LRELREVIAFESKSQHECKDHDESPRSSSKVAEPENVSSSGQTAKIAIDTSTESPTEWNP
RNSSLKKQENAPVRDTSSVLEKIAEFHKHQHARGRDATTGSLHRTLSIHTTAIEQTYMAE
ECDENDYHFDLDSYKPVQPITFDHGIALFPVAAPHSGMDLHLLQVLHHGTTLVHWDCEGG
TTRTALVFARVDRACGTFVWEKPPWSPLKTAQLGGTASADFSLTANPEDVVSAGLVGRYT
MQQTDCASVTLEEGFLDLSSVKEVMIGCCDRDRETDLRSIYKRYGLSGSDSCIGLMYGSS
LPDNRLIFLLCPPALSKIWYMGLCWILRGLKRQQQLTDRRSRWLKEKYLQLYFEDGCIEP
MTADAIRAFGGRDWSTTESIGTLSPTSSSALRKRNVKGKKTKSIGNIHALTKDLSLKQYD
TSSPDGGLTVVPSRHITGSRESLTRIIPASPRSSRDRVPPRSPPGSAERIISSNLPYSSF
QSLLCVARDKDKNGSGMSGGVEAPWQAKARATSIMYETQLNFVEFVALFRSFSLRARKDL
RDLFGQLAITCRSQSDGSLRDFNVRPPVLRQTSDATPQRIGLLTRNNSIDCHEYKTSSNL
QKKQVFDAVAAASIVNNCSGVDTSKSQVITLATFTKFLESRQQEKLTDDEIKALVKRHEP
DPGLRTQWCLSFEGFARYMMDKDNYAFPNEYATPFETEMQQPLSQYYIASSHNTYLTGHQ
LKGESSVQLYSQVLLTGCRCVELDCWDGDDGSPVIYHGHTFTTKIPFRLVVEAIDRSAFV
SSPYPVILSIENHCSQSQQARMAQIFQSVFGEKLVTKFLFETDFSDDPQLPSPSQLRYRI
LIKNKKMVVEPAGPLTHAPLSHRGKMLMSDRASSMKQMRTDVSSASVVEYFSEDDDDEED
DDEDDNIDDNSISSYERYLGGMQVPHGRLKSDSAVDDKSQKQSSQIAKELSDLVIYLQAI
KFRGLNTTPGTTATGKVRHQPHTGPVQRHSIAGIGATSIGASSGSPQSLSTSASLASGGS
NIENLFRFTRGVPACFQCSSLNESTAKKICRKQPLGVVAHAETQLIRTYPAGMRIDSTNF
NPVIFWAFGIQMVALNYQTDDAGLNLNAAMFEQNGQCGYVRKPSVMWDKGHMMYRRFNPW
DKEFDGLHSAHLTLSIVSGQYVSPTNFVASTYVEIELVGIPIDCAKHKTKIIQNNALNPI
WNEKFCFQVMFKDLAFLRFGIVEASSHHLIAQRVIPLKCLKPGYRHVRLRSCKNKPLALS
TLFIYSRLEEESLDYNTCCRDHKESSKRPSSGKEPEKLTTVDPGLGGVTLKRRMFFLMVY
HVIPEEPYTILKVTQDSTTQEVMLQALQKAGISADRVDEYILVEEVSRGWEKRDREELPT
QRVLDPTEHPLQAQALWKGQGRFLLKRVGDDPSSRAWLASIRSTAGHSKLDSERDTSTHI
WDEADTFLVCIYNVSPDIPYAILRVPVSSSAQDVLAQALVKARRMEDPMKFALVEELEWG
GAGAVGSGSRQLRVLRDEENVYSTQAFWKTLGRFILREREQAIPRRHLLPATLDRLSKGF
SVGRSVSLPGSSKEKMPVSEALSDPTSRGLRHRLLMHGRRREVHSDGEDIRESDILNAAL
HLKKVSLRKLRVWKS
NT seq 5088 nt   +upstreamnt  +downstreamnt
atggaaattgtcgccggtctcaagtgccacaagctaaagcccttttggcaaagtgtgaac
gacccagtaccagttttggaaaatctatcctccgcccttttgtctcccgagtatgagctc
gcgcttgctcgctccttggcaatgccagagtgtccagtggtgccgttctttggagctttt
ttgcgggaattgcgggaagtcatcgcattcgagtccaagtctcagcatgaatgcaaggac
cacgacgagtcgccgcgtagcagcagcaaggttgccgagcccgaaaacgtgtcatcttcg
gggcaaacggcaaaaattgctattgataccagcaccgaatcgcccacggaatggaatccg
aggaatagttccttgaaaaagcaagagaacgctccagtccgtgatacaagctccgttctc
gagaaaattgccgaatttcataagcaccaacatgctcgaggcagagacgcgacgactggc
tcgcttcatcgcacgctcagcattcatacgaccgcgatcgagcaaacctacatggccgaa
gaatgtgacgagaacgactatcatttcgatctcgattcctacaagccggtacaaccgatc
acattcgaccatgggattgcgttatttcctgtcgctgcaccgcactccggaatggatctg
catcttttgcaggtattgcatcacgggacaacgttggtgcattgggactgcgaaggcggt
acgacgaggacggccttagtattcgcgcgagtggatcgcgcttgcggtaccttcgtgtgg
gaaaagccaccctggagtccattgaaaactgcccagctgggaggtacagcttctgcagat
ttttcgctaactgccaatccagaagacgtggtatcggccggtttagtagggagatatacc
atgcaacagacggactgcgcttccgtgacgctggaagagggatttttggacctgagctcc
gtcaaggaagtcatgatcggctgttgcgatcgggacagagagaccgacctcagaagcatt
tacaagagatacggtctatctggatccgattcatgtatcggccttatgtacggctccagt
ctgccggacaatcgactgatctttctcctttgccctcctgcgcttagcaaaatttggtac
atgggtctttgttggatactacgaggcctgaaacggcaacaacaactaacagatcgtaga
tcgcgatggttaaaagaaaaataccttcagctttatttcgaggatggatgtatcgagcca
atgacagctgatgctattagagcttttggcggtcgcgactggtccacgactgaaagtatc
ggcacgctttcgccgacgagcagcagcgctctccgcaaacgaaacgttaaagggaaaaaa
acgaaatctatcggcaatattcatgcgttaacaaaggatctaagcctaaaacagtatgac
acttcgtctccggatggaggcttaacagtggtcccttctcggcatattacgggtagtaga
gaatccttgacgagaatcataccagcatctccacggtccagcagagatcgagttccccca
cgtagtcctcctggatccgccgaacgaattattagttccaacttgccttactccagcttt
caaagcctattatgcgtcgccagggacaaggataaaaacggatctggaatgtcaggtgga
gtggaagcaccttggcaagcgaaggcacgtgccacttccataatgtatgaaactcagttg
aacttcgtcgagtttgtcgcgttgttccgttcgttcagcctgagagcaagaaaggattta
cgcgacctattcggccaactggcgatcacttgtcgtagtcaaagcgacggttctttgaga
gactttaacgtacggccgcctgtgttgaggcaaaccagtgacgcaacccctcaacgaatc
ggtctcttgacgagaaataactccatagactgtcacgagtacaaaaccagcagcaatctt
caaaagaaacaagttttcgacgcggtggctgcagctagcatcgttaataattgttctggc
gttgacacttcgaaatcgcaagttatcaccctggcgacgttcactaagtttttggaatct
cggcagcaagaaaaactaaccgacgacgagatcaaggcgctggttaagcgacacgaaccg
gacccaggactacgtacacaatggtgtttgtctttcgagggctttgcacggtacatgatg
gacaaggacaattatgccttcccaaacgagtatgcgacgccgttcgagactgaaatgcag
cagccattgtcccagtattacatcgctagctcgcataatacttatttaactggccatcaa
ctcaagggagaatcttcggtgcagctttactctcaggtactactaacaggatgtaggtgt
gtagagttggattgctgggatggcgatgatggctctcccgttatttaccatggtcacacc
ttcactaccaagataccatttcgcttggtcgtagaggcgattgatagaagtgctttcgtc
agttctccatatcccgtgattctctccatcgagaatcattgttcgcagagtcaacaagct
cgaatggcccaaatatttcaatcggtatttggagaaaaactggtgacaaagttcctgttt
gagacggactttagcgacgaccctcaactgccatcgccgtcgcaattgcgctaccgaata
ttaatcaaaaacaagaagatggtggtagaacccgctggtcctttgacgcacgctcccttg
agtcatcgtggaaaaatgctcatgtccgatcgagcttcgtctatgaaacaaatgcgtacc
gacgtaagcagcgcttccgtcgtcgaatattttagcgaagacgacgacgatgaggaagat
gacgacgaagacgacaatatcgatgataactccatttccagctacgaaaggtatttgggt
gggatgcaggtgccccatggtcgattaaagtcagattccgcggtcgacgataagtcgcaa
aaacaaagtagccaaattgccaaagaactttcggatttggtgatttacttgcaagctatt
aaatttcgcgggctgaacactacgccaggaacaacggccactgggaaggtgcgacatcaa
ccgcacactggaccggttcagagacacagcatcgctggaataggagctaccagcatcggt
gcctcttccggatcgccacagtctttatcgacgtcggcttcgctcgcaagcggcggcagc
aatatcgaaaatctcttcagattcacgcgcggagttccagcctgctttcaatgttcctcg
ttgaatgaaagcacagcgaagaagatttgcagaaaacaacctctaggggttgtcgcccat
gcagaaactcagttaattcgaacgtatccggctggaatgcgtattgattcgacaaatttc
aatcccgtgatcttctgggcctttggtattcaaatggtagcactaaattaccaaaccgac
gacgccggattaaatttaaacgccgctatgttcgagcaaaatgggcaatgtggatacgtt
aggaaaccttcggttatgtgggacaaaggccatatgatgtatagacgcttcaatccttgg
gataaagaattcgacgggctacattcggcacacctgacgctttcaatagtctctggccag
tatgtttccccaacaaatttcgtcgccagcacgtacgtcgaaatcgaactagtcggcatt
ccgatcgactgtgccaagcataaaacgaaaataatacaaaacaacgcgctgaatcctatt
tggaacgagaaattttgctttcaagtaatgttcaaagaccttgcctttctgcgtttcggc
atcgtcgaagcaagttcccatcatttgatcgcccaaagggtcattccgctgaaatgcttg
aagcccggctacagacacgtacgtttgcgttcctgtaaaaacaaacctttggctctgtcc
acgctgttcatttattcccgtttggaagaggagagtctcgattacaacacgtgttgccgt
gatcacaaagagtcgtcgaagcggccgtcatcgggtaaggaaccggaaaaattgaccacg
gtggatcctgggttaggtggagtgacgctgaagagaagaatgttcttcctaatggtttat
cacgtgataccggaggaaccgtacactatattaaaagtcacgcaggatagtacgacgcaa
gaggtaatgttacaagctcttcagaaagctggaatatccgcggatcgggtcgacgaatat
attttggtggaagaggtctctcgtggttgggagaagagagacagggaagaacttccgact
caacgcgtgttagatccaacggagcacccgttgcaagcgcaggctttatggaaggggcag
gggcgtttcctcttgaagagggtaggcgatgatcctagcagcagagcctggctggcttct
ataaggagtacagctggacactcgaagctcgactccgaaagagacacatccacgcatatc
tgggacgaagctgacaccttcttagtttgcatttataacgtttcgccggatataccgtac
gcgatacttcgcgttcctgtaagcagctctgctcaagatgttctggctcaggctttagtg
aaggccagaagaatggaggatccgatgaagtttgctttggtggaagaactggaatgggga
ggagccggagccgttggtagcggcagtcgacaattgagagttttacgcgacgaggagaac
gtgtacagtactcaagccttttggaagacgctcggaagattcattctgagagaaagagaa
caagcaataccgaggcggcatctgttgccagccaccttggataggctcagcaaaggtttt
tccgtaggaagatcggtctccttgccaggttccagcaaggagaagatgcctgtctcggaa
gcgctttccgatccaacttccagaggattgagacatcgtctactgatgcacggtcgtagg
agggaagttcactccgatggcgaagatattcgcgagtctgatattttaaacgcggccctt
cacttgaagaaggtatccttaagaaaattaagggtttggaagtcatag

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