Bos indicus (zebu cattle): 109559331
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Entry
109559331 CDS
T04792
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00260
Glycine, serine and threonine metabolism
biu00630
Glyoxylate and dicarboxylate metabolism
biu00670
One carbon pool by folate
biu01100
Metabolic pathways
biu01200
Carbon metabolism
biu01230
Biosynthesis of amino acids
biu01240
Biosynthesis of cofactors
biu01523
Antifolate resistance
biu04981
Folate transport and metabolism
Module
biu_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
109559331 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
109559331 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
109559331 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
109559331 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109559331 (SHMT2)
Enzymes [BR:
biu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
109559331 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
109559331
NCBI-ProteinID:
XP_019816531
UniProt:
A0A6P5BTH7
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Position
5:complement(60596523..60603775)
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AA seq
504 aa
AA seq
DB search
MLSFSFIWATRPLRRCGQLVGMAVRCQHSEAAQTQTGEASKGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQILKNSQA
MANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSH
QLADLRQRVEQFARAFPMPGFDDH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccgtacggtgccagcacagtgaggcggcccagactcagactggagaagcaagc
aagggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctg
cggagagagaaggacaggcagtgtcgcggcctggagctcattgcttcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacggaggagcagaggtagtggatgagatagagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgctcagtggggagtcaatgtccaaccc
tactccggatccccagccaatctggctgcctacacagcccttctgcagcctcacgaccga
atcatggggctggacttgcccgatgggggccatctcacccacggctacatgtctgatgtc
aagcggatctcagctacatctatcttcttcgagtctatgccttataagctgaacccccaa
accggcctcattgactatgaccagctggcactcactgctcggctcttcaaaccacgactc
atcatagctggtaccagtgcctatgctcgtctcattgactacgcccgcatgagagaagtg
tgtgacgaggtcaaggcacacctcttggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacccttcaagcacgcggatattgtcaccacgaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgcaggctgtggac
cccaaaactggccgagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcctgcacccccatgttccgggagtactccctgcagattctaaagaactctcaggcc
atggctaatgccctgctggagcgaggctactccctggtgtctggtggcactgacaaccac
ctagtgctggtagaccttcggccaaagggcctggacggagctcgagcagaacgggtgttg
gaacttgtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacc
cctgggggcctgaggctgggggccccagccctgacttctcgagggttccttgaagatgac
ttccggaaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagc
aagaccaccaaactccaggatttcaaatctttcctgctcaaagacccagaaacaagtcat
cagctggccgaccttaggcaacgggtggagcagttcgccagggccttccccatgcctggt
tttgatgatcactga
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