Bos indicus (zebu cattle): 109560805 Help Entry 109560805         CDS       T04792                                  Symbol OBSCN Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism biu  Bos indicus (zebu cattle) Pathway biu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:biu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     109560805 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:biu01001]     109560805 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:biu04131]     109560805 (OBSCN) Enzymes [BR:biu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      109560805 (OBSCN) Protein kinases [BR:biu01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    109560805 (OBSCN) Membrane trafficking [BR:biu04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     109560805 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 Ig_4 PK_Tyr_Ser-Thr C1-set Ig_6 C2-set_2 fn3 RhoGEF SOS1_NGEF_PH Ig_DSCAM-DSCAML_C PH ABC1 Kinase-like IQ Pkinase_fungal DUF6406 DUF1722 Motif Other DBs NCBI-GeneID:  109560805 NCBI-ProteinID:  XP_019818853 UniProt:  A0A6P5C027 LinkDB All DBs Position 7:complement(2583357..2822193) Genome browser AA seq 9833 aa AA seqDB search MDHSSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDRQLVEAGGRFRLAQ DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDADAACAEQAPHFLLRPTSIR VREGAEATFRCRVRGSPPMSVSWAKDGRRLGVLDAPRVRVEESGEASALRIRAAQPRDSG TYTVHAENPLGAASAAAGLTVDAEAEAANPPGASTAMLLAHLQRRREAMRAGGAPASPPS AGTRTCTVTEGKHARLSCFVTGEPKPEIVWKKDGQLVVEGRRHVVYEDEQENFVLKILFC KQSDCGLYTCTASNLVGQTYSSVLVVVREPTVPFRKRLQDLEVPEKASATFQCEVPVPAM ESAWYKEETRLWASAKYLIEEAGAERRLTVLNVSSDDDAVYICETAEGSRTVAELAVRGN LLRKLPRKTAVRVGDTAMFCVELAKPEGPVQWLWNQKAVVAGGRVAITAEGTCHTLTISQ CSLEDVGEVAFVAGDCRTSTQFCVSAPRRPPLHAPEAPVVKAQTESSVTLGWSPPPAGDR PAAIEGYLVEKKRLGAYTWSRCHEDEWVTTPELTVAGVAEEGEFQFRVSAVNSFGQSPYL EFPGTVHLAPQLAVKTPLKAVEAVEGGEVTFSVDLTTASSGEWFLDGRVLKASSVYVIQR DGTRHTLTIRSVPVSLHGAELKFVANGIESSIRMEVRAPLELTAKRPAPAAAAREVLARL HEEAQLLAELSDQAAAVTWLKDGHTLSPGPKYEVQASAGQRALLVRDVKREDAGLYECVS RGSRIAYQLLVQESSAVFIKGQPMHKEVKAVAGASATLSCEVAQAQTEVTWYKDGKKLSS SSKVHVEAKGCTRQLVVQQAGKADAGEYSCEAGGQKVFFHLDVTEPSVVFAKEQPARSEV QAVAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKXDAGEY SCEAGGQKVSFHLDVTEPSVVFAKEQPARSEVQAVAGTSATLSCEVAQAQTEVMWYKDGK KLSSSSKVRVEATGRGRRLVVQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVFAKEQPAR SEVQAVAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRKLVVQQAGKADA GEYSCEAGGQKXSFRLDVTEPSVVFAKEQPARSEVQAVAGTSATLSCEVAQAQTEVTWYK DGKXLSSSSKVRVEATGXGRRLVVQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKE QPARSEVQAVAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVHLEAKGCTRQLVVQQAG KADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPARSEVQAVAGASATLSCEVAQAQTEV TWYKDGKKLSSSSKVRVEATGRGRRLVVQQAGKADAGEYICEAGGQKVSFRLDVTEPSVV FAKEQPAHSEVQAVAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGRTRQLVV QQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPARSEVQAVAGASATLXCEVAQA QTEVTWYKDGKKLSSSSKVRVEAKGCTRQLVVQQAGKADAGEYSCEAGGQKVSFRLDVTE PSVVFAKEQPARSEVQAVAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEATGRGR RLVVQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPARSEVQAVAGASATLSCE VAQAQTEVTWYKDGKKLSSSSKVHVEATGRVRRLVVQQAGKADAGEYSCEAGGQKVSFRL DVTEPSVVFAKEQXARSEVQAVAGASATLSCEVAQAQTEVTWYKDGKRLSSSSKVRVEAT GRXWRLVVQQAGKADAGEYSCEAGGQKVSFCLDVTEPSVVFAKEQXACSEVQAVAGASAT LNCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRQLVVXXXGKADAGEYSCEAGGQKV SFRLDVTEPSVVFAKEQPARSEVQAVAGSSATLSCEVAQAQTEVTWYKDGKKLSSSSKVR VEAKGCTRKLVVQQAGKADAGEYSCEAGGQKVSFRLDVXEPXVVFAKEQPAXSEVQAKAG ARTTLSCEVAQAQTEVTWYKDGKKLSSSSKVHVEAKGCTRQLVVQQAGKADAGEYSCEAG GQKVSFHLDVTEPEFEXPAPEKPRRREPLVVREHEDIILTATLATPSVATVTWFKDGVEI RRSKRHEMASLGDTHTLTMRGAQTLDSAVYSCRVGTEGQDFPVQVEEVAAKFCRPLEPVS GDLGGTVTLVCELSPAQAEVVWRRGSTQLRXGKRFQMAAAGPRRSLTVSGLRAEDAGEYV CESRDDHTSAMLTVIVPRVVKFTSGLSAVVAEEGSEATFQCVVTPSDVAVTWFRDGVQLQ SSEKFLISQKGASHSLTILSLALEDAGQVTAQAEGIQSTAALRVREAPVLFRKKLEPQTX EERSSVTMEVELTRPWPEVKWTRNAVALASGEKVEIHAEGARHRLVLHGVGFADRGFYGC ETPDDKTQAKLTVEMRQVRLVRGLQAVEAQEQGXATMEVELSHADVEGNWTRDGLRLQPG PNCQLAVHGPTHTLTLSRLQRQDGGLVAFRAEGVHTSAHLVVTELPVKFVRPLQXVVATE KEKVALDCELSRPNVDVRWLKDNVELRVSKTMGMMAQGACRSLVIYRCELGDQGVYVCDA HDAQSSASLKVQGRNVQIVRPLEDVEVVEKEGATFSCEVSHDEVPAQWFWEGSKLRPSDN VRIRQEGRTYTLIYRRVLVEDAGEIKFVAENAESRAQLRVKELPVSILRPLRDKIAMEKH RGVLECQMSRASAQVRWFKGSVELHPGAKYEMVSDGLYRKLVINAVQPEDEDTYTCDAGD VKTSAQFFVEEQSIVVVRGLQDVTVMEPAPAWFECETSIPSVRPAKWLLGKTVLQAGPDV GIEQEGTVHRLTLRRTYSTMTGPVHFTIGKSRSTASLVVSDIPVVLTRPLEPKVGREMQS VVLSCDFKPPPKAVQWYKEETPLAPSSKFKMRLEGHMAELRVLRLTPDDAGVYRCQAGSA QSSAEVTVEERKVTVTQPLEDVEVAEEGRACFSCELSHEDEEVDWLLNGTPVFNDSFHEI THEGRRHTLVLKRVRQADRGTVSISSPKVAASAHLAVRGKPVVFLKALDDVSAEERGRLT LQCEVSDHQAHVVWRKDGVELGPSDKYDFLHTAGTRGLVVHSLTREDAGLYTCHVGTDET RARVSVHELHVGITKRLKTVEVLEGESCSFECILSXEDTGDVAEWTVSGKTVGSSGRFCA TRQGRKYTLAIRDAXPSDAGEVVFSVRGLTSKASLIVKEXSVDIMKPLEDQQAMLGEDVV LRCELSREGTPVRWLKDGKAIRKSQKYDLLTEGTRASLVIHAATLKDSGKYTCETESSKS TASLQVEEKANRFTEPLADLHVEEKGTATFTCKTERPAVSVAWRKGLTELQASGKHAPSQ EGLTLRLTISALEKADSDTYTCDIGQAQSQARLLVKGQKVLIIEDLEDAEVQEGSSATFC CRISPADYKPVHWFLDKTPLSANELNEIEAQPGGYHVLTLRQLALKDSGTVHFEAGDQRT SAALQVTEKPSVFSQGLTDATVTEGEDLTLVCETSVSDSPVCWTKDGKPLRPSARCRLTY EGRRAQLVITETTLQDSGRYKCEAAGAWSSSIVRVHARPVQFREGLKDVEVLEGGAATLR CVLSSVVRPVEWRRGDELLQPGGKYSLRQDGTVLELVVRDLRPQDSGQYFCSFGDQRTSA RLTVKALPAEFIGRLRSKEVTEGTTXTFRCELSKEAPVEWKKGPETLRAGDRVSLRQDGA VCELEIRELTAEDAGEYSCVCGQEKTSATLTVRALPAEFTRRLRSKEATEGTTVTLHCEL SKAAPVEWRKGPETLRAGARVSLRQEGAVCELEIRELTVEDAGEYLCVCGQERTSATLTI RALPAKFTKGLKKEEAVEGATAILRCELSKAAPVEWKKGPETLRAGARVSLRQEGAVCEL EIRELTVEDAGEYSCVCRQEKTSATLAVRALPASFXKGLKKEEATEGATVTLCCELSKAA PVEWRKGLETLRAGDRVSLRQEGAVCELEIRDLTVEDAGEYSCMCGQEKTSATLAVRALP XKFAKGLRKEEATEGTTVTLRCELSKAAPVEWRKGPETLRAGARVSLKQDGAVCELEIRE LTVEDAGEYSCVCGQERTSATLTVRALPAKFMKGLKKEEAVEGATAKLRCELSKAAPVEW RKGPETLRAGARVSLRQEGVXCELEIRELTXEDAGEYSCVCGQERTSATLTVRALPAKFT KCLKKEEAVEGATAILRCELSKAAPVEWRKGPETLRAGARVXLRQEGAVCELEIHGLTVE DAGEYSCVCGQEKTSATLAVRALPAKFIKGLKKEEAVEGATAKLLCELSKAAAVEWKKGP ETLRARDRVSLRQEGTLCELEIRDLTVEDAGEYSCVCGQEKTSATLAIRALPAKFTKGLK KEEAVEGATAKLRCELSKAAPVEWRKGPETLRAGARVSLRQEGAVCELEIRGLTVEDAGE YLCMCGHEKTSATLAIRAMPARFIKELKTKEATEGATATLRCELSKAAPVEWRKGPEPVR AGDRVIQRQEGAVCELAIRELTVEDAGEYSCVCXQEKTSATLAVRALPAKFAKGLGKEEA MEGATAILCCELSKAAPVEWRKGPKTLRAGGRVSLRQEGAVCELEIRDLTVEDAGEYSCV CGQEKTSATLAVRALPAKFTKGLKKEEATEGATAILRCELSKAAPVEWRKGPETLRAGDR VRVKQEGAVCELEIRGLTVEDAGEYSCMCGQEKTSATVAVRALPAKFLKGLRKEEATEGA TAKLRCELSKAAPVEWRKGPETLRAGDRLRVRQDGAVCELEIRELTTDDAGEYSCVCGQE KTSATLAVRALPAEFIGRLRSKEATEGATVTLCCELSKAAPVEWRKGPKTLRAGDRVSLR QEGAVCELEIRELTADDAGEYSCVCGQEKTSATLAIRALPAEFIGRLRSKEATEGATVTL CCELSKAAPVEWRKGSETLRAGDRVSLRQDGAVCELEIRELVSTDAGEYSCVCGQERTSA SLTVTAPQVVFRKPLQSLQAEEGTSASLRCELSEPGATVVWSKGGLEVQADGRREPRQQG HVAELVLRGLRREDTGEYTCSCGSQATSATLSVTAAPVRFLRELQAQEVDEGTTARLRCE LSRAGSSVEWRKGSLQLFPCAKYQMVLEGTAAELLVHGAEQEDAGLYTCDTGHAQSTASL SVRAPRPVFKTELQSAEQEVGGVARLCCQLSDSEAGAPVLWLKEGVELHMSPKYEMQRQG ATCELLIHGLEAKDMGEYSCMVGSQKTLAFLKVKEPEVTIVRGLVDTEVQADGEAEFSCE VSQAGVDVEWRLQGLPLQSNEVTEVAVQGGRTHILRLKSVTPEDAGTVSFHVGRHTSSAQ LTVRVPEVTILEPLQDXQLSEGQDAHFWCRLSRALGQEAHWALGGVPLQANEMNDITVEH GTLHSLTLHKVTLEDAGTISFQVGSCRSEAQLKVTAKNTVVRGLENVEAPEGGEALFECV LSQPEVAAHTWLLDDEPVHTSDNAEVVYFENGLRHLLLLKNLRPQDSCRVTFLXGDMVTS AFLTVRGWRLEVLEAPQDVTVRAGGQASFSCTLSETVPVGEATWYINGASVQPDDADWTV TADGXHHALLLHRAQPQHAGEVTFAAXDAVASARLTVLGLPDPPEDAEVVGRSGSSVTLS WVAPTSDGGGGLRGYRVEMKAAATGEWQLCHDLVPGPECVVAGLAPGETYRFRVAAVGPA GAGEPVYLPQMVKLAEPLEPRPAAPAPESRQVAAGEDVCLECEVAEAGEVVWLKGTERVQ PSGRFQLLQQGQRQMLLIRGFSTEDQGEYRCAPARDSASGSAXAFQVVLTPESGEEVPAQ PSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDCRPXXXXXEAEEAVPDLS EEYSTADELARTGEADLSHTSSDDESRAGTPSLVSYLKKAGRPSPSPLASKVGAPAAPSG KPQEKQQEKPPAVYPPPGDLSAGDLXDPTLDQAAVKIQAAFKGYKVRKEMQQQEGPVLRC TFGDTVAQVGDVLHLECVVSSKTDVRARWLKDGVELTDSRHHHIDQLADGTCSLLVTSLG RADAGRYTCQVSNKFGHVAHSATVVVSGTESENESSSGGELDDTFRRAARRLHRLFRTKG PEEVSDEEIFFSADEGKAEPEEPGDWQTYREDEHSICICFETLAEARXAASRFQEMFGVL GIXVDVSLSELGPRRVEMRIGKVAPAPSAPLEPVLAAEAAPVFLTELQNQEVLDGYPVSF DCVVTGQPVPTVRWFKDGRMLEEDDHYMISEDQQGGHQLIITAVVPADMGVYRCLAENSV GVSSTKAELRVDLTSTDYDTAADATETSSYFSAQGYLSSREQEGTESTSEEGQLPQVVEE LKDLQVAPGTRLAKFQLKVKGYPTPRLYWFKDGQPLTASAHIRMADRKMLHTLEVVSVTS EDAGQYSAYISNXVGAAYSSARLLVRGPDEPEEKPALDARQQLVPPRFLEKFTSKKVKKG SSITFSVKVEGSPPPAVHWLREEAEQGVLWISRHTPGYTVASSAQQHSLVLLDVGRQHQG TYTCIASNAAGQALCSAGLHXSGLPKEAGATEEQPEVKEALISTFLQGTQAVAAQMSEPA TFTDLAGQKKELLAAEARSHLSLAEVGTEEFLKKLTSQITEMVSAKITQAKLQVPGVDSD EESKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAILLR EGQYVEVLDSAHPLRWLVRTKPTKNSPSRQGWVSPAYLDKRLKLSPEWGPAEAPEFPGEA LSEDEYKTRLSAIIRDLLSSEQSFVGELQFLQSHHMQYLDRCPHVPAAVASQKAVIFRNV QDIGHFHSSFLQELRSCDTDDDVAMCFIKNQAAFEKYLEFLVGRVQAESXXXXTAVQEFY KKYTEEVLSAADPSQPPPPPLQHFLEQPVERVQQYQALLKELIRNKARNGQNCALLEQAY AVVSALPQRAENQLHVSLMENYPGTLEALGEPIRQVGLRVRGGPWELSSIDLNDQVEGDD RAFEIWHEREDSVRKYLLQARTVITKNSWVKEICGIQQRLALPIWRPPDFEEELADCTAE LGETVKLACRVTGTPKPIVSWYKAKLQVPGVDSDEESKTPSASPRHGRSRPSSSVQESSS ESEDGDSRGEIFDIYVVTADYLPLGAEQDAILLREGQYVEVLDSAHPLRWLVRTKPTKNS PSRQGWVSPAYLDKRLKLSPEWGPAEAPEFPGEALSEDEYKTRLSLPQELIRNKARNGQN CALLEQAYAVVSALPQRAENQLHVSLMENYPGTLEALGEPIRQHGLSAARQSACALLPQL SSIDLNDQVEGDDRAFEIWHEREDSVRKYLLQARTVITKNSWVKEICGIQQRLALPIWRP PDFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCALI LDNLTGADSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRAXPFVDGEDAQITCTIEG APYPQIRWYKDGALLTPGGKYQTLSEPRSGLLVLEIRAAGTEDLGIYECELVNRLGSKRS RXELLMQSPVLQAREQHRVERLAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPS KSPSRYGHTASLPRPGLLAPELPPSPEASRPSRPEAVPGXXXAVPTLFVTEPETHTAGPP GGTRPPPKWVEVEETIEVRVKKTGSKGASLARETPGSSEQLHFTLPGRVSGRDPNTNNSN NKLLTQEPPAAVTVGEPLIVCVETGPESPEXSPPWGAEEGALLEEGERDAYEVEEPLGAD GLQGRDPKILTHHGRALTLADLEDYVPREGETFGCSGPRPSAADDPPCEISVLQREISEP TVGQPVLLNVGRPPDSRAPPGCFGRMPRSREAFPSGPQGRGPTGVSFCFREAQAGGAATQ KPSFCTQVQRSADSGQSSFKTEVSTQTVSFGTVGETVTLHIRPDRDMDPSPSQDAAVPAP AAPGQESTSIQRTQTCPEAPGPSTGDHSSPSPSPGGLPALQGASPEPPAVEAGAASSEAW QQVEGEPPKAPQPLSHEGLKQTAQARTEVLERTVPIRMEGAAWPGAGELWDVHSHVFTET THRTYVYQTSDTPAASPPSMQVTIEDVQAQRGSTAQFQAVIEGNPQPTVIWYKDGTQLGA DPRLSQQQEGTTYSLVLRDVTQHDAGVYTCLAHNPGGQVLCKAELLIHGASPSLATRDSE HSSRRKLHSFYEVLEEIGRGVFGFVKRVQHKGNQMACAAKFIPLRSRTRAQAYRERDILA GLSHPLVTALLDQFETRKTLILILELCSSEELLDRLFKKSVVTEAEVKIYIQQLVEGLQY LHGQGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPGEPQYSKYGSPEFVAPEIIEQ TPVNEASDIWAMGVITYLSLTCSSPFAGESDRATLLNVLEGRVSWSNPMATHLSEDAQDF IKAALQKAVGARPSAAKCLAHPWFRKSVPAEEAHFINTKQLKFLLARSRWQRSLMSYKSI LVMRSIPELLQGPPDSPSLGIARHLRGDASASSSSSSSSDNELAPFARAKSLPSSPVTHS PLLHPRGFLRPSASLPEEAEACPPAAASALPASLQGEEPAAALGCVPRQSIIRSLFYQQV GEGPELGGPSTGGRRHPARRRHLLKGGYFSGVLPGLREPLLEHRALEEAAAMEEQAAQQA TAASLETAVQMPRASTQEASGSSHSRDRDPPNTASSSTKACSKGQCPAPAPLSPQDAQGE GTPGGGARAREKEHPEGTPRGLRLPSASSDGCSIQPQESSQDRCGGQAAPFSKPQWVPAP QDTVPPASLAPQPSGSFPSGPCTEALLSSPSPSFPGKPQACLPPAQASPQVDSQSGLKAV PLTKRPGSPRPPEPASQMGTEPSPSLDAEGLVQETEDLSPSSPSLQRPQEQATTRKFSLG CRGGYAGVAGYGTFAFGGDAGGMLGQGPMWAKMTWAVSQSSEEQDEAATESPPPQASTAP APEGDGTLRRASQELSSWEDIGGXSQVSLVQIQDLSRDPEAADTVSLDISEVDPAYLNLS DLYDIKYLPFEFMIFRKIPKPVEPERPSSPESEAGEELAELPEAAWPXPASLEITEEPED MEALLGKAAGGRKRKWSPPSGSLFHFPGRHSLLEEPTELGLRQRVKASVAHISRLLRGRP EGLEKESPPRKKAGLASFRLKSKDRAPSFLRELSDETVVLGQSVTLACQVVAQPAAQATW SKDGALLESSSRLLISSTLKNFQLLTILVVTAEDLGMYTCSVSNALGTAATTAILRKAER PSSSPRPDIGEVHADGVLLVWKPVESYGPVTYIVQCSLEGGSWSTLASDVFDCCYLTGKL SRGGAYTFRTACVSKAGMGPYSSPSEQVLLGGPSRLASEEESGATGPARPLPSMQTFAFQ TQMRRGRFSVVRQCREKASGRMLAAKIVPYHPADRAAVLREYEALKSLRHPHLAQLQAAY LSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQILSATQYLHAQGILHLDLRSE NMIVTEYNLLKVIDFGNAQSLAQERVLPSERFKDYMETMAPELLEGQGAVAQTDIWAIGV TAFIMLSAEYPVNGEGTRDTQKGLRKGLIQLSRCYAGLSGGAVAFLRSTLCVHPWVRPCA SSCLQSPWLTEEGPASSQPAAVTFPTTGLRVFVREREKRRALLYKKHNLAQVR NT seq 29502 nt NT seq  +upstreamnt  +downstreamnt atggatcactcctccttcagcggtgcaccccgcttcctaacccggcccaaggccttcgtg gtatcggtgggcaaagatgccacgctgagctgccagattgtgggcaaccccacgccgcaa gtgagctgggagaaagaccggcagctggtggaggcgggtggtcgcttccgcctggcccag gacggcgacctgtaccgcctgaccatcctggacctggcgctgggcgatagtgggcaatat gtgtgccgtgcgcgcaacgccatcggcgaggccttcgcggcggtcggcctgcaggtggac gccgacgccgcgtgcgccgagcaggcgcctcacttcctgctgcggcccacctccatccgc gtgcgcgagggcgccgaggccaccttccgctgccgcgtgcgcggttcgccgcccatgtcg gtgagctgggccaaggacgggcggcgcctgggtgtgctggacgccccccgagtgcgagtg gaggagagcggcgaggcgagcgctctgcgcatccgggctgcacagccgagagacagcggc acctatacggtgcacgcggagaacccgctgggcgccgccagcgccgccgccgggcttacg gtggacgcggaggcagaggcagccaacccgccgggggcctccaccgccatgctcctggcg cacctgcagcggcggcgcgaggccatgcgcgccgggggcgccccggcctcgccgccgagc gccggcacgcgcacctgcacggtgacagagggcaaacacgcgcgcctcagctgcttcgtg acgggcgagcccaagcctgagatcgtgtggaagaaggatggacagctggtggtggagggc cggcggcacgtggtgtatgaggacgagcaggagaacttcgtgctgaagatcctcttctgc aagcagtcagactgtggcctctacacctgcacggcrtccaaccttgtgggccagacctac agctcggtgctggtcgtygtgagagagcccacagtgcccttcagaaagcgcctgcaggac ctggaggtgccggagaaggcatcagccacgttccagtgtgaagtaccggtgccagccatg gagtctgcctggtataaggaggaaacgcggctgtgggccagcgccaagtacctcatcgag gaggcgggcgcygagcgtcggctgaccgtgctgaacgtctcctccgaygacgaygccgtg tacatctgtgagacggcagagggcagtcgcacggtggctgagctggcagtgcgaggcaac ctccttcggaagctcccaaggaagacagctgtacgagtgggagacacygccatgttctgt gtggagctggccaagcccgagggccccgttcagtggctgtggaaccagaaggcggtggtg gctgggggccgggtggccatcactgctgagggcacgtgccacacgctgaccatctcccag tgcagcctggaggatgtgggtgaggtggcctttgtggctggggactgccggacgtctacc cagttttgcgtgtcagcccccaggaggccgcccctgcatgctcctgaagcccccgtggtg aaggcccagacagagagctccgtaactcttggctggtccccgccacctgctggggaccgc cctgctgccatcgagggctacctggtggagaagaagaggctgggtgcctatacctggagc cgttgccatgaagatgagtgggtgaccacgcckgagctgactgtggctggcgtggccgag gagggagagttycagttcagggtgtcagctgtgaacagctttggccagagcccctacctc gagttcccaggaactgtacacctggctccccagctggctgtgaaaacacctctgaaggca gtggaggcagtrgaaggcggcgaggtgaccttctctgtggacctcactacggcctcatca ggggagtggttcctggacgggmgggtcctgaaggccagcagtgtgtatgtgatacagcgg gatggcacccgccacactctcaccatccgctcggtgcctgtcagcctgcacggggcggag ctcaagttcgtggccaatggcatcgagagcagcatccgcatggaggtccgagcgcccctg gagctgacggccaagcgtccggcaccagcagcggccgctcgggaggtgctggcccggctg catgaggaggcccagctcctggccgagctgtcggaccaggcggcagccgtgacgtggctc aaggacggacacacgctgtctcccggccccaagtatgaggtgcaggcttcagctgggcag cgggcactgctcgtgcgggacgtgaagcgagaagacgcgggcctgtatgagtgcgtcagc cgtgggagccgcatcgcctaccagctgctggtgcaagagtcctctgcagtgtttatcaag gggcagccaatgcataaggaggtaaaggccgtggcgggggcgagtgccacgctgagctgc gaggtggcccaggcccagacggaggtgacgtggtacaaggacgggaagaagctgagttcg agctcgaaagtgcaygtggaggccaagggctgcacccggcagctggtggtgcaacaggcg ggcaaggcggacgccggggagtacagctgcgaggccgggggccagaaggtcttcttccac ctggacgtcacagagccctccgtggtgttcgccaaggagcagccggcacgcagtgaagtg caggccgtggcgggaaccagtgccacactgagctgcgaggtggcccaggcccagacggag gtgacgtggtacaaggacgggaagaagctgagttccagctcgaaagtgcgtgtggaagcc aagggctgcaccaggcggctggtggtgcagcaggcgggcaaggyggacgccggggaatac agctgcgaggccgggggccagaaggtctccttccacctggacgtcacagagccctcrgtg gtgttcgccaaggagcagccggcacgcagtgaagtgcaggccgtggcgggaaccagtgcc acgctgagctgcgaggtggcccaggcccagacggaggtgatgtggtacaaggacggcaag aagctgagttccagctcgaaagttcgtgtggaggccacgggccgcgggcggcggctggtg gtgcagcaggcgggcaaagcggacgccggggagtacagctgcgaggctgggggccagaag gtctccttccgcctggacgtcacagagccctcggtgtttgccaaggagcagccagcacgc agtgaagtgcaggccgtggcgggaaccagtgccacgctgagctgcgaggtggcccaggcc cagacggaggtgacgtggtacaaggatgggaagaagctgagttcgagctcgaaagtgcgt gtggaagccaagggctgcacccggaagctggtggtgcagcaggcaggcaaggcggatgcc ggggagtacagctgcgaggccgggggccagaagstctccttccgcctggacgtcacagag ccctcrgtggtgttcgccaaggagcagccagcacgcagtgaagtgcaggccgtggcagga accagtgccacgctgagctgcgaggtggcccaggcccagacggaggtgacatggtacaag gacgggaagargctgagttccagctcgaaagtgcgtgtggaggccacgggcygcgggcgg cggctggtggtgcagcaggcgggcaaggcggacgccggggagtacagctgcgaggccggg ggccagaaggtctccttccgcctggacgtcacagagccctcagtggtgttcgccaaggag cagccagcacgcagtgaagtgcaggccgtggcgggggcgagtgccacgctgagctgtgag gtggcccaggcccagacggaggtgacatggtacaaagacgggaagaagctgagttcgagc tcgaaagtgcatttggaagccaaaggctgcacccggcagctggtggtgcagcaggcgggc aaggcggatgccggggagtacagctgcgaggccgggggccagaaggtctccttccgcctg gacgtcacagagccctcagtggtgttcgccaaggagcagccggcacgcagtgaagtgcag gccgtggcgggggcgagtgccacgctgagctgtgaggtggcccaggcccagacggaggtg acgtggtacaaggacgggaagaagctgagttccagctcaaaagtgcgtgtggaggccacg ggccgcgggcggcggctggtggtgcagcaggcgggcaaggcggatgctggggagtacatc tgtgaggccgggggccagaaggtctccttccgcctggacgtcacagagccctcggtggtg ttcgccaaggagcagccggcacacagtgaagtgcaggccgtggcgggggcaagtgccacg ctgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaaggacgggaagaag ctgagttccagctcgaaagtgcgtgtggaggccaagggccgcacccggcagctggtggtg cagcaggcgggcaaggcggatgccggggagtacagctgcgaggccgggggccagaaggtc tccttccgcctggacgtcacagagccctcggtggtgttcgccaaggagcagccggcacgc agtgaagtgcaggccgtggcgggggcgagtgccacgctgarctgygaggtggcccaggcc cagacggaggtgacatggtacaaggacggcaagaagctgagttcgagctcgaaagtgcgt gtggaagccaagggctgcaccaggcagctggtggtgcagcaggcgggcaaggcggacgcc ggggagtacagctgcgaggccgggggccagaaggtctccttccgcctggacgtcacagag ccctcggtggtgttcgccaaggagcagccagcacgcagtgaagtgcaggccgtggcgggg gcgagtgccacgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaag gacggcaagaagctgagttcgagctcaaaagtgcgtgtggaggccacgggccgcgggcgg cggctggtggtgcagcaggcgggcaaggcggacgccggggagtacagctgcgaggccggg ggccagaaggtctccttccgcctggacgtcacagagccctcggtggtgttcgccaaggag cagccggcacgcagtgaagtgcaggccgtggcgggggcgagtgccacgctgagctgcgag gtggcccaggcccagacagaggtgacgtggtacaaggacggsaagaagctgagttcgagc tcaaaagtgcatgtggaggccacgggccgcgtgcggcggctggtggtgcagcaggcgggc aaggcggacgccggggagtacagctgcgaggccgggggccagaaggtctccttccgcctg gacgtcacagagccctcggtggtgttcgccaaggagcagcmrgcacgcagtgaagtgcag gccgtggcgggggcragtgccacgctgagctgcgaggtggcccaggcccagacggaggtg acgtggtacaaggacgggaagaggctgagttccagctcgaaagtgcgtgtggaggccacg ggccgnnnntggcggctggtggtgcagcaggcgggcaaggcggacgctggggagtacagc tgcgaggctgggggccagaaggtctccttctgcctggatgtcacagagccctcggtggtg ttcgccaaggagcagcyggcatgcagtgaagtgcaggccgtggcgggggcgagtgccacg ctgaactgcgaggtggcccaggcccagacggaggtgacgtggtacaaggacggcaagaag ctgagttccagctcgaaagtgcgtgtggaagccaagggctgcacaaggcagctggtggtg cnnnnnnnnggcaaggcggatgcyggggagtacagctgcgaggccgggggtcagaaggtc tccttccgcctggacgtcacagagccctcggtggtgttcgccaaggagcagccggcacgc agtgaagtgcaggccgtggcagggtcgagtgccacgctgagctgcgaggtggcccaggcc cagacggaggtgacrtggtacaaggatgggaagaagctgagttcgagctcgaaagtgcgt gtggaagccaagggctgcacccggaagctggtggtgcagcaggcgggcaaggcggacgcc ggggagtacagctgcgaggccgggggccagaaggtctccttccgcctggacgtcrcagag cctrtggtggtgtttgccaaggagcagccggcaygcagtgaagtgcaggccaaggcaggc gcccgcaccacactgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaag gatgggaagaagctgagttcgagctcgaaagtgcatgtggaggccaagggctgcacccgg cagctggtggtgcagcaggcgggcaaggcagacgccggggagtacagctgcgaggccggg ggccagaaggtctccttccacctggatgtcacagagccggagtttgagmccccggcccca gagaaacccagacgcagggaaccgctggtggtcagggaacacgaggacatcatcctgaca gccactctggccacgccgtctgtggccacggtgacgtggttcaaagatggtgtggagatt cgccgcagcaagcggcacgagatggccagcctaggggacacccacaccctgaccatgcgt ggggcacagaccctggacagcgctgtctacagctgccgcgtgggcacagaggggcaggac ttcccggtacaggtggaagaggtggctgccaagttttgccgccccctggagcccgtgagc ggggatctgggcggcacggtgacgctggtctgtgagctgagycctgcgcaggctgaggtg gtgtggcgccgcggaagcacgcaactccggkccggcaaacgcttccagatggcggctgcg gggcctcggcgctcgctcacggtgtcgggcctgcgggcagaggatgcaggggagtacgtg tgtgagagccgcgacgaccacaccagcgccatgctcactgttatcgtaccccgygtggtc aagttcacgtctgggctgagtgcggtggttgcggaggaggggagcgaggccactttccag tgcgtggtgacccccagcgacgtggcrgtcacatggttccgagacggtgtccaactacag tccagcgagaagtttctcatctcgcagaagggtgccagccacagcctgaccatcttaagc ctggccctggaggatgccggccaggtcactgcgcaggctgagggcatccagtccacrgct gccctccgggtccgagaggctccagtgttgttcagaaagaagctggagccacagaccrtg gaggagcggagctcagtgaccatggaggtggagctgactcggccgtggccggaggtcaag tggacacgcaatgctgtagcactcgcgtcgggcgagaaagtggagatccacgccgagggt gcacgccaccgtctggttctccacggtgtgggtttygctgaccgtggcttctacggctgc gagacaccagacgacaagacacaggccaagctgactgtggaaatgcgccaggtccggctc gtgcggggcctgcaggccgtggaggcgcaggagcagggcayggccactatggaagtagag ctgtcccacgctgacgtggagggcaactggactcgagacggtcttcggctccagccagga cccaactgccagctggcggtgcacggccccacacacaccctcacgctgtcacggctgcag cggcaggacggtggcttggtggccttcagggcggagggcgtgcacacctctgctcatctg gtggtcactgagctgcctgtgaagttcgtccgccctctgcaggrcgtggtggccacagag aaggaaaaggtggccctggactgtgagctctcacgccccaatgtggatgtgcgctggttg aaggacaacgtggagctgcgggtaagcaagaccatgggcatgatggcccagggggcctgc aggagtctcgtcatttaccgatgtgagctcggagaccagggcgtgtatgtgtgcgatgcc cacgatgctcagagctcggcctccctgaaggtgcaaggccggaatgtgcagatcgtgagg cctctggaggatgtggaagtggtggagaaagagggcgccaccttctcctgtgaggtctcc cacgatgaggtgcctgcgcagtggttctgggagggcagtaagctgcggcccagtgacaac gtgaggatccgccaggaaggaaggacatacactctcatctatcggagagtcctggtggaa gatgcaggggaaatcaagtttgtagcggaaaatgcagaatcgcgagcccagctccgagta aaagagctgcctgtgtccatcctccgcccgctgcgggataagatygccatggagaagcac cgcggcgtgcttgagtgccagatgtccagggccagtgcccaggtgcggtggttcaagggt agcgtggagctccatcccggagccaagtacgagatggtcagtgacggcctctaccgcaag ctggtcatcaacgccgtccagcccgaggacgaggacacctacacgtgtgatgccggcgat gtgaagaccagtgcacagttcttcgtagaagagcagtccatcgtggtcgtgcggggcctg caggatgtgacggtgatggagccggcgcccgcctggttcgagtgtgagacctccatcccc tcagtgcggcccgccaagtggctcctggggaagacggtgctgcaggcggggcctgacgtg gggatagagcaggagggcacggtgcatcggctgacgctgcggcgcacctactccaccatg acggggccggtgcacttcaccatcggcaaatcgcgctccaccgcctccytggtggtctct gacattcctgtggtgctcacacggcccctggagcccaaggtggggcgggagatgcagtcc gtcgtcctgtcctgtgacttcaagcctccccccaaggctgtgcagtggtacaaggaggag acgcccctggcgccatccagcaagttcaagatgaggctggagggccacatggcggagctg cgtgtcctgcggctcacccctgacgacgctggggtctaccggtgccaggctggcagcgcc cagagcagcgcggaggtcactgtggaagaacggaaggtgacggtgacgcagccgctggag gacgtggaggtcgcggaggagggccgtgcctgcttctcctgcgagctgtcccacgaggac gaagaagtggactggttgctcaacgggacaccggtctttaacgacagcttccatgagatc acccacgagggccgccgccacacactggtgctgaagcgggtccggcaggctgacaggggc accgtgagcatctcctcccccaaggttgcggcctccgcccacctggcggtcagagggaag ccggtggtgttcctgaaggcgttggacgatgtgtctgcagaggagcggggcagactgacc ttgcagtgcgaggtttctgaccaccaagcccacgtggtgtggcggaaggacggtgtggag ttgggtcccagtgacaagtacgacttcctgcacacggcgggcacgcgaggcctcgtggtg cacagcctgactcgggaggatgctggcctgtacacctgccacgtgggcactgatgagacc cgtgcccgtgtcagcgtgcatgagctgcaygtgggcatcaccaagaggctgaagacagtg gaggtgctggagggcgagagctgcagcttcgagtgcatcctgtcccrtgaggacactggc gacgtggctgagtggacagtgagcgggaaaacagtgggcagctctggccgcttctgtgcc acgcgccagggccgcaagtacactctagctatccgagatgccrygccaagtgacgctggg gaggtggtcttctctgtgcggggcctcacctccaaggcctcgctcatcgtcaaagagarg tcagttgacatyatgaagccactggaagaccagcaggccatgctgggtgaggatgtggtg ctgaggtgtgagctgtcacgggaggggaccccggtgcgctggttgaaggatgggaaggcc atccgcaagagtcagaagtatgacctgctcactgaaggcactcgggcctcgctggtcatc catgcagccacactcaaagactcgggcaaatacacatgtgagacggagtcttccaaaagc acagccagtctccaagtggaagaaaaggcaaaccggttcacggagccgttggctgacctg cacgtggaggagaagggcacagccacgttcacctgcaagacggagcgccccgcggtctcc gtggcctggcgcaagggcctcacggagctgcaggcctcggggaagcacgcgcccagccag gagggcctgaccttgcggctcaccatcagcgccctggagaaggcagacagtgacacctac acctgcgacattggccaggcccagtcccaggcgcggctcctggtgaaaggccagaaagtg ctcatcatagaggacttggaggacgcggaggtgcaggagggctcctcrgccaccttctgc tgccgtatctcccctgcygactacaagcctgtccactggttcttggacaaaacgcccctg tctgccaatgaactcaatgagattgaggctcagcccggtggataccatgtgctcaccctg cggcagctggcgctcaaggactcgggcaccgtccattttgaggcaggtgaccagcgaacc tcagctgccttgcaggtcacagagaagccaagtgttttctcccaggggctcacggatgcc acagtcacggagggggaggatctgaccctggtctgtgagacttccgtctcagacagccct gtgtgctggaccaaggatgggaagcccctgcggccatcggcccggtgccggctgacctat gagggccgccgggcccagctggtcatcactgagaccaccctgcaggacagcgggcgctac aagtgtgaggctgcgggcgcctggagcagctccattgtcagggtccacgctcggccagtg caattccgagagggcctgaaggacgtggaggtgctggaggggggcgctgccacgctgcgc tgcgtgctgtcgtctgtggtcaggcctgtggagtggcggcgtggggatgagctcctgcag cctggaggcaagtacagcttgcggcaggacgggaccgtgctggagctggtggtccgagac ctgcggcctcaggacagcgggcagtacttctgcagtttcggggaccagaggacgtcggcc aggctcaccgtcaaggctctgcctgctgagttcataggaagactgagaagcaaggaggtc acggaagggaccacakccacattccgctgtgagctcagcaaggaagcccccgtagagtgg aagaaggggcccgaaaccctcagagccggggacagagtgagcctgaggcaggacggggcc gtgtgtgagctggagatccgtgagctgaccgccgaggatgctggrgaatattcatgtgtg tgtgggcaggagaaracctcagccacgctcaccgtcagggctttgcctgctgagttcaca agaagactgagaagcaaggaggccacagaagggaccacagtcacgctgcactgtgagctg agcaaggcggcccctgtggagtggaggaaggggcccgagaccctcagagccggggccaga gtgagcctgaggcaggagggagccgtgtgtgagctggagatccgtgagctgaccgtggar gatgctggggagtacttgtgtgtgtgcgggcaggagaggacctcggccacactcaccatc agggccctgcctgccaagttcacaaagggtctgaagaaggaagaggccgtggaaggggcc acagccatactgcgctgtgagctgagcaaggcagcccccgtggagtggaagaaggggccc gagactctcagagccggggccagagtgagcctgaggcaggagggagccgtgtgtgagctg gagatccgtgagctgaccgtggargatgctggagaatattcatgtgtgtgcaggcaggag aagacctcagccacacttgccgtcagggccctgcctgccagcttcamaaaaggtctgaag aaggaagaggccacrgaaggggccacagtcacgctgtgctgtgagctgagcaaggcggcc cccgtggagtggaggaaggggctggagaccctcagagccggggacagagtgagcctgagg caggagggagccgtgtgtgagctggagatccgtgacctgaccgtggaggatgctggggag tactcgtgcatgtgtgggcaggagaagacctcagccacgctcgccgtcagggccctgccc rccaagttcgcaaagggcctgaggaaggaggaggccacagaagggaccacggtcacgctg cgctgtgagctgagcaaggcrgcccccgtggagtggaggaaggggcccgagaccctcaga gccggggccagagtgagcctgaagcaggatggagccgtgtgtgagctggagatccgtgag ctgaccgtggaggatgctggggagtactcctgcgtgtgcgggcaggagaggacctcagcc acgctcaccgtcagggccctgcctgccaagttcatgaagggtctaaagaaggaagaggcc gtggaaggggccacagccaagctgcgctgtgagctgagcaaggcggcccccgtggagtgg aggaaggggcccgagaccctcagagccggggccagagtgagcctgaggcaggagggagty rtgtgtgagctggagatccgtgagctgacnnnngaggatgctggggagtactcctgcgtg tgcgggcaggagaggacctcagccacgctcaccgtcagggccctgcctgccaagttcaca aaatgtctgaagaaggaagaggctgtggaaggggccacagccatactgcgctgtgagctg agcaaggcggcccctgtggagtggaggaaggggcccgagaccctcagagccggggccaga gtgcrcctgaggcaggagggagccgtgtgtgagctggagatccatgggctgaccgtggag gatgctggggagtactcctgcgtgtgcgggcaggagaagacctcagccacactcgccgtc agggccctgcctgctaagttcatcaagggtctaaagaaggaagaggccgtggaaggggcc acagccaagctgctctgtgagctgagcaaggcagccgccgtggagtggaagaaggggccc gagactctcagagccagggacagagtgagcctgaggcaggagggaaccctgtgtgagctg gagatccgtgacctgaccgtggaggatgctggggagtattcctgcgtgtgtgggcaggag aagacctcagccacgctcgccatcagggccctgcctgccaagttcacaaaaggtctgaag aaggaagaagccgtggaaggggccacagccaagctgcgctgtgagctgagcaaggcggcc cccgtggagtggaggaaggggcctgagaccctcagagccggggccagagtgagcctgagg caggagggagccgtgtgtgagctggagatccgtggcctgaccgtggaggatgctggggag tacttgtgcatgtgtgggcatgagaagacctcagccacgctggccatcagggccatgcct gctcggttcatcaaagaactgaagaccaaggaggccacggaaggggccacagccacactg cgctgtgagctgagcaaggcggcccccgtggagtggaggaagggscctgagcccgtcaga gccggggacagagtgatccaaaggcaggagggagccgtgtgtgagctggcgatccgtgag ctgaccgtggaggatgctggggagtactcgtgtgtgtgcrggcaggagaagacctcagcc acgctcgccgtcagggccctgcctgccaagtttgcaaaaggtttgggaaaggaagaggcc atggaaggggccacagccatactgtgctgtgagctgagcaaagcagcccctgtggagtgg aggaaggggcccaagaccctcagagctggaggcagagtgagcctgaggcaggagggagcc gtgtgtgagctggagatccgtgacctgactgtggaggatgctggagaatattcatgtgtr tgcgggcaggagaagacctcagccacactcgccgtcagggccctgcctgccaagttcaca aaaggtctgaagaaggaagaggccacagaaggggccacagccatactgcgctgtgagctg agcaaggcggcccccgtggagtggaggaaggggcccgagaccctcagagccggggacaga gtgcgggtgaagcaggagggagccgtgtgtgagctggagatccgtgggctgaccgtggag gatgctggggagtactcgtgcatgtgcgggcaggagaagacctcagccacagtcgccgtc agggccctgcctgccaagttcctgaagggtctcaggaaggaggaggccacggaaggggcc acagccaagctgcgctgtgagctgagcaaggcggcccccgtggagtggaggaaggggccc gagaccctcagagccggggacagactgcgggtgaggcaggacggggccgtgtgtgagctg gagatccgtgagctgaccacggatgatgctggagaatattcatgtgtgtgcgggcaggag aagacctcagccacactcgccgtcagggctttgcctgctgagttcataggaagactgaga agcaaggaggccacagaaggggccacagtcacgctgtgctgtgagctgagcaaggcggcc cccgtggagtggaggaaggggcccaagaccctcagagccggggacagagtgagcctgagg caggagggagccgtgtgtgagctggagatccgtgagctgaccgcggatgatgctggagaa tattcatgtgtgtgcgggcaggagaagacctcagccacactcgccatcagggctttgcct gctgagttcataggaagactgagaagcaaggaggccacagaaggggccacagtcacgctg tgctgtgagctgagcaaggcggcccccgtggagtggaggaagggatctgagaccctcaga gccggggacagagtgagcctgaggcaggacggggccgtgtgtgagctggagatccgtgag ctggtttcgacagacgctggggagtactcatgtgtgtgcgggcaggagaggacctcagcc tcgctgacggtcacggccccacaggtggtgttccggaagccgctgcagagcctgcaggct gaggagggtacctcggccagcctgcggtgtgagctttccgagcctggggccaccgttgtc tggagtaaggggggcctggaggtgcaggccgatgggcgccgggagccacggcagcagggc cacgtggcagagctggtgctgaggggcctgcgccgggaggacacgggagagtacacctgc agctgcggctcccaggccactagcgccaccctgtccgtcacagctgcgcctgtgaggttc cttcgagagctgcaggcccaggaggtagacgagggcacgacggcacgcctgcgctgtgag ctgagccgggcgggcagcagtgtggagtggcgcaagggttccctgcagctcttcccgtgt gccaagtaccagatggtgctggaaggcacagccgctgagctgctggtgcacggggccgag caggaggatgctggmctctacacctgtgacacgggccacgcgcagagcaccgccagcctc tctgtccgggcccccaggcctgtatttaagacggagctgcagagtgctgagcaggaggtg ggcggcgtggccaggctgtgctgccagctgagtgattccgaggctggggcccccgtgctc tggctcaaggagggtgtggagctgcacatgagtcccaagtatgagatgcagcgccaggga gccacgtgtgagctgctgatccatgggcttgaggccaaggacatgggcgagtacagctgc atggtgggcagccagaagaccttggccttcctcaaagtcaaagagcctgaggtgaccatc gtgmggggcctggttgacacygaggtccaggctgatggggaagcagagttcagctgcgag gtgtcacaggctggcgtggacgtggagtggcgcctgcagggcctgccgctgcagagcaac gaggtgaccgaagtggcggtgcagggtggccgcacccacatactgaggctgaagagcgtg accccggaggacgccggcactgtctccttccacgtgggccgccacacrtcctctgcccaa ctcaccgtccgagttcctgaggtgaccatcctggagcccctgcaggacrctcagctcagc gaaggccaggaygcccacttctggtgccgactgtcgagggctttgggccaggaggcccac tgggccctgggaggcgtgcccctgcaggccaacgagatgaacgacatcaccgtggarcat ggcacactccactcgctcaccctgcacaaggtcacccttgaggacgctggaaccatcagt ttccaagtgggctcgtgtcgctcagaggcscagctgaaggtcacagccaagaacacggtg gtgaggggcctggaaaacgtggaggcgcccgagggcggcgaggcgctgttcgagtgcgtc ctgtcccagccggaggtggccgcccacacctggctgctggacgatgagcccgtgcacacc tctgacaatgccgaggtggtctacttcgagaacggcctgcggcacctcctgctgctcaaa aacctgcggccacaagacagctgccgcgtgaccttcctggygggggacatggtgacgtct gccttcctcaccgtcagaggctggcgtctggaggtcttggaggcgccccaggaygtgacc gtgcgtgccggggggcaggccagcttcagctgcacccttagcgagacggtgcccgtgggc gaggcgacctggtacataaacggagcctccgtgcagcccgatgacgcggactggaccgtc acggccgacggcarccaccacgccctgctgctgcaccgggcccagccgcagcacgccggc gaggtcacctttgctgctcrcgatgctgtcgcctctgcgaggctcactgtgctgggcctc cccgaccccccagaggatgcagaggtggtggggcgcagcggcagctccgtgacgttgtcc tgggtggcccccacaagcgatggcggagggggtctccgtggctaccgggtggagatgaag gcagcagccacgggagagtggcagctgtgccacgatctggtgcccgggcctgagtgtgtg gtggctggcctrgcccccggggagacctaccgcttccgcgtggctgcagtgggcccggcg ggcgctggggagcccgtttacctgccccagatggtgaagctcgcagagcccctggagccc aggcctgcggcccccgcccccgagagccggcaggtggcggccggggaggacgtgtgtctg gagtgcgaggtggccgaggcgggtgaggtcgtctggctgaaggggacggagcgcgtccag ccgagcgggcgcttccagctgctccagcagggccagcggcagatgctgctgatccggggc ttctccacggaggaccagggcgagtaccgctgygcccctgcacgggactcagcctctggg tcagctrctgctttccaggtggtgctgaccccagaatccggggaggaggtccctgctcag cccagcctgccccctgaggcagcccaggagggcgacctacacctgctgtgggaggcgctg gcccggaagcgccgcatgagccgmgagcccacgctggactccatcagcgagctgcctgag gaggattgccgcccacannnnnnnnnnnnggaggccgaggaggccgtgcctgacctctca gaggagtactccacggctgacgagctggcgcgcacgggcgaggccgacctttcgcacacc agctctgacgacgagtcccgtgcaggcacgccttcgctggtttcctacctcaagaaggct gggaggcccagcccctcgccactggccagcaaggttggggccccagcagccccctcaggg aagccacaggagaagcagcaggagaagccacctgcagtatacccaccaccaggagacctg agcgctggggacctgrgtgacccgaccttggaccaggccgcagtgaagatccaggcrgcc ttcaagggttataaggtccggaaggagatgcagcagcargaggggccygtgctccgctgc acatttggggacactgtggcacaggtgggagacgtcctgcatctggagtgtgtcgtgtcc agcaagacagatgtgcgcgcccgctggctgaaggatggtgtggaactgacggacagccgg caccaccacattgaccagcttgcggayggcacctgttctctgctggtcactagcctgggg cgggccgacgctggccgttacacctgtcaggtgagcaacaagtttggccacgtggcccac agtgccaccgtggtggtcagtggcacggagagcgagaacgagagctcctccgggggtgag ctggatgacaccttccgccgggccgcccggcggctgcaccgcctcttccgcacgaaaggc ccagaggaggtctcggacgaggagatcttcttcagcgctgacgagggcaaggcagagcct gaggagcctggggactggcagacrtaccgcgaagatgagcactccatctgcatctgcttt gagacgctggcggaagcccgccrggcagccagccgcttccaggaaatgtttggcgtgttg ggcatcmgtgtggacgtcagcctgtccgagctgggaccacgcagggtggagatgcgcatt ggcaaggtggcacccgccccttcagccccgctggagccagtgctggcggcagaggctgcc ccggtgttcctgaccgagctacagaatcaggaggtgctggatgggtaccctgtgagcttt gactgtgtggtgacaggccagcctgtgcccaccgtgcggtggttcaaggatgggaggatg ctggaggaggatgaccactacatgatcagygaggatcaacagggtggycaccagctcatc atcacggctgtggtgccrgcagacatgggtgtctaccgctgcctggccgagaacagtgtg ggtgtgtcctctacaaaggccgagctccgwgtggacctgaccagcaccgactatgacact gctgcggacgccacggagacctcgtcctacttcagtgcccagggctacttgtccagccgg gaacaagagggtacagagtctacctcagaggaggggcagctgccccaggtggtggaggag ctgaaggacctgcaggtggcccccggcacgcggctggccaagttccagctcaaggtgaaa ggctaccccacacctcgactctactggttcaaagacgggcarcccctgaccgcatctgcr cacatacgtatggcggacaggaagatgctccacactctggaggttgtctctgtcaccagc gaggatgcagggcagtactcggcctacatcagcaacrccgtgggtgctgcttactcctct gctcggctcctggtccgaggccccgatgaaccagaagagaagccagcattagatgcacgc cagcagctggtcccaccccggttcctggagaaattcacctccaagaaggtgaaaaaaggt tccagcatcactttctccgtgaaggtggaaggaagcccaccgccrgctgtgcactggctg cgagaggaagcggagcagggtgtgctgtggatcagccgccacacgccaggctacacggtg gccagctctgcccagcagcacagcctggtcctgctggacgtgggccgacagcaccagggc acctacacctgcatcgcctccaacgccgccggccaggccctctgctcygcaggcttgcac rtctctggcctgcctaaggaggcgggggccacggaggagcagccygaggtgaaggaggcc ctcatctccaccttcctgcaggggacccaagctgttgctgcacagatgtcagaacctgca actttcacagaccttgctgggcagaagaaagagctcctggcagcagaggcccgtagccac ctgtccttggccgaggtgggcacggaggagttcctgaagaagctcacttcgcagatcaca gagatggtgtcggccaagatcacacaggcaaagctgcaggtgcctggagttgacagtgat gaggaatcgaagacgccatccgcatccccccggcacggccgttcacgcccgtcttccagt gtccaggagtcgtcctcagagtccgaggacggggactcccgaggagagatctttgacatc tatgtggtcacggctgactacctgcccctgggggctgagcaggatgccatcttgctgcgg gagggccagtaygtggaggtcctggactctgcccaccctctgcgctggctcgtgcgcacc aaacccaccaaaaacagcccctctcggcagggctgggtgtcccctgcctacctggacaag cggctcaagctgtctcctgagtgggggccagcagaggcccctgagttccctggggaggct ttgtcagaggacgagtacaagacgaggctgagtgccatcatccgggacctgctgagctca gagcagtcctttgtgggcgagctgcagttcctgcagagccaccacatgcagtacctggac cgctgcccccatgtgcccgcagccgtggccagccagaaggcagtcatcttcagaaacgtg caggacatcggccacttccacagcagcttcttacaggagttgcgtagctgtgacacagat gacgacgtggccatgtgcttcatcaagaaccaggcagcctttgagaagtatctggagttc ctggtgggccgagtgcaagccgagtcgnnnnnnnnnnnnacggccgtgcaggagttctac aagaaatacactgaggaggtgctgtcagccgcggacccctcgcagccaccgcccccaccg ctgcagcacttcctggagcagccggtagagcgggtgcagcagtaccaggccctgctcaag gagctgatccgcaacaaggcgcggaacggccagaactgcgcgctgctcgagcaagcctac gcggtggtgtcggccctgccgcagcgagcggagaaccagctgcacgtgtcgctcatggag aactaccctggcaccctggaggccctgggcgagcccatccgccaggtggggctgagggtg cggggagggccttgggagctgagcagcatcgacctgaacgaccaggtggagggcgatgac cgagcctttgagatctggcacgagcgggaggactccgtgcgcaagtacctgctgcaggca cggacggtcatcaccaagaactcctgggtgaaggagatctgtggcatccagcagcgcctg gccttgcccatctggcgcccccccgattttgaagaagagctggctgactgcacagctgag ctgggtgagacagtcaagctggcctgccgtgtgacgggcacacccaagcccattgtcagc tggtacaaagcaaagctgcaggtgcctggagttgacagtgacgaggaatcgaagacgcca tccgcatccccccggcacggccgttcacgcccgtcttccagtgtccaggagtcgtcctca gagtccgaggacggggactcccgaggagagatctttgacatctatgtggtcacggctgac tacctgcccctgggggctgagcaggatgccatcttgctgcgggagggccagtatgtggag gtcctggactctgcccaccctctgcgctggctcgtgcgcaccaaacccaccaaaaacagc ccctctcggcagggctgggtgtcccctgcctacctggacaagcggctcaagctgtctcct gagtgggggccagcagaggcccctgagttccctggggaggctttgtcagaggacgagtac aagacgaggctgagtcttccacaggagctgatccgcaacaaggcgcggaacggccagaac tgcgcgctgctcgagcaagcctacgcggtggtgtcggccctgccgcagcgagcggagaac cagctgcacgtgtcgctcatggagaactaccctggcaccctggaggccctgggcgagccc atccgccagcacggcttgtctgcggcccggcagtcagcctgtgccctcctcccacagctg agcagcatcgacctgaacgaccaggtggagggcgatgaccgagcctttgagatctggcac gagcgggaggactccgtgcgcaagtacctgctgcaggcacggacggtcatcaccaagaac tcctgggtgaaggagatctgtggcatccagcagcgcctggccttgcccatctggcgcccc cccgattttgaagaagagctggctgactgcacagctgagctgggtgagacagtcaagctg gcctgccgtgtgacgggcacacccaagcccattgtcagctggtacaaagatgggaagcca gtggaggtggaccctcaccacatcctcattgaagaccccgatggctcgtgcgcgcttatc ctggacaacttgactggtgccgactctggccagtatatgtgctttgcagccagtgctgct ggcaatgccagcaccctgggcaaaatattggtgcaagtcccrcctcggtttgtgaacaag gtccgggcartgccctttgtggatggagaagatgcccagatcacctgcaccatcgaaggt gccccatatcctcagatcaggtggtacaaggatggggccctgctgacccctgggggcaaa taccagaccctgagtgagccccgcagyggccttctggtgctggagatccgggcagctggc acggaggatctgggcatctatgagtgtgagttggtgaaccggctgggctccaagcggagc cgtgyggagctgctcatgcagagccccgtgctgcaggcccgggaacagcaccgygtggag cggcttgcggccgtggaagtcactgagcaggagactaaggtccccaagaaaaccgtcatc atagaggagaccattaccactgtggtgaagagcccccgtggccgacgccagtcccccagc aagtctccctcccgctacggtcacaccgccagcctgcccaggccaggcctgctggcccct gagctgccaccctcgccagaggccagcagaccctccaggcctgaggcggtgccaggnnnn nnnnnngccgtgcccactctgttcgtgacggagcctgagacccacacagcaggcccgccg gggggcactaggcccccgcccaaatgggtggaggttgaggagaccattgaggtccgggtg aagaagaccggctcaaagggtgcgtctctggccagagagacgcctggcagctctgagcag cttcacttcacgctgcctggaagggtgtctggaagagaccccaatacaaacaactccaat aacaagctgctgacccaggagcccccggccgcrgtcaccgttggagagcccctaattgtc tgcgtggaaacggggccagagagccctgagcygtcccctccctggggtgctgaagaggga gccctgctggaggagggggagagagatgcctacgaggtggaggagccgctgggtgctgat ggtctgcagggccgtgatcccaagatcctcacacaccacggtcgtgccctcaccctggcc gacctggaggattacgtgccccgggaaggggagacctttggctgcagtggccccaggccg agtgccgctgatgacccgccctgcgagatctcggtgctgcaragagagatcagcgagccc accgtgggccagcccgtcctgctgaacgtggggcgtcccccagactcccgggccccccct ggctgcttcggccgcatgcccaggtcccgggaggcatttccatcggggccgcagggccgg ggccccacgggcgtctccttctgctttcgggaggcccaggccggaggcgccgcgacccag aagccttccttctgcactcaggttcagcgstctgcggacagcggccagagcagcttcaaa accgaggtttcaacccaaacrgtcagctttgggactgtgggggagactgtcaccctacac attcgcccagacagggacatggaccccagcccctcccaggatgctgccgtcccagcccca gctgccccagggcaggaaagcacgtccatccagaggacacagacgtgccctgaggctcca ggaccttccacaggggatcacagcagccccagccccagccctggggggctacctgcactc cagggggccagcccggagcccccagctgtggaggctggggccgcatccagtgaggcctgg cagcaggttgaaggcgagcctccgaaggcacctcagcctctctcccatgagggcctcaag cagacggctcaggcacgcactgaggtcctggaacgcacagtgcccattcggatggagggc gctgcctggccaggagcaggtgagctctgggacgtccacagccacgtgttcacggagacc acacacaggacatacgtgtaccagaccagcgacacgcctgctgcaagccccccgtccatg caggtcaccatcgaggacgtgcaggcccagaggggcagtacggcacagttccaggctgtc atcgagggcaacccacagcccacagtgatctggtacaaggacggcacccagctgggagct gacccccggctcagccagcagcaggaagggaccacctactccctggtgcttagggacgtg acccagcacgatgcgggcgtctacacctgcctggcccacaaccctggcggccaggtgctg tgcaaggcagaactgctgatccacggggcttccccttctctggctacacgggacagtgag cacagctctaggaggaaactgcactccttttatgaggtcctggaggaaattggaaggggt gtgttcggcttcgtgaagagggtgcagcacaagggcaaccagatggcctgtgctgccaag ttcattccactgcggagcaggacgcgtgcccaggcttatcgggagcgggacatcctagca ggcctgagccacccgctggtcaccgcactgctggaccagtttgagacgcggaagaccctg atcctcatcctggagctgtgttcgtcggaagagctgctagaccgcctgttcaagaagagt gtggtgaccgaggccgaggtcaagatctacatccagcagctggtggaggggctgcagtac ctgcacggtcaaggcatccttcacctggacataaagccccccaacatcctgatggtgcat cctgctcgggaagacattaaaatctgtgattttggctttgcccaaaaaatcaccccggga gagccacagtacagcaagtacggctcccctgagtttgtggcccccgagatcatcgaacag acccccgtgaacgaggcttccgacatctgggccatgggggtcatcacctacctcagcctg acctgttcatccccatttgctggagagagtgaccgagcaacccttctgaatgtcctggaa gggcgggtgtcctggagtaaccccatggccacccacctcagtgaggacgcccaggacttt atcaaggctgctctgcagaaggctgtgggggctcggcccagtgctgccaagtgcctcgcc cacccctggttccggaagtctgtgcccgcggaggaggcccacttcatcaacaccaagcag ctgaagttcctcctggcccgcagtcgctggcagcgctccctgatgagctacaagtccatc ctggtgatgcgttccatcccagagctgctccagggcccgcccgatagcccatccctcggg attgcccggcatctgcgtggcgacgccagcgcctcctccagcagctcctcctcctccgac aacgagttggccccgttcgcccgggccaagtcgctgccatcctccccggtgacccactcc ccactgctgcacccccggggcttcctgaggccttcggccagcctgcctgaggaggccgag gcctgtccacctgctgcagcctcggctctgcctgcatcgctgcagggcgaggagccagca gcggccctgggttgtgtgccccggcagagcatcatccggagcctattctaccagcaggtg ggcgaaggcccagagctcgggggcccgtccacagggggcaggcggcaccctgcccgccgg cggcaccttctcaagggtggctacttctcgggcgtcctgccgggacttcgagagccactg ctggagcaccgggcactggaggaggcggctgccatggaagagcaggctgcccagcaggcc acagcagcctccttggagacggccgtgcagatgcccagagcaagcacccaggaggcctct ggctccagccactcccgggaccgtgacccaccaaacactgccagttcctccaccaaggcc tgcagcaaggggcagtgtcccgctccggctcccctgagtcctcaggatgcccaaggagag ggcacgcctggaggaggtgcacgtgccagggagaaggagcatccagaggggaccccgcgg gggctgagactgccctccgccagtagtgatgggtgctccattcagccacaggagtcgtcc caggaccgctgtggagggcaggctgcccctttctctaagccccagtgggtcccggccccc caggatactgtcccccctgcgtccttggcaccacaaccttctggctccttcccttcaggg ccctgcacagaggccctcttgtcatcccctagcccttccttcccaggaaagccacaggcg tgtctgccccctgcccaagcgagcccccaggtagactctcagagcgggctgaaggccgtc cctctcaccaagaggcctggatcacccagacccccagagccagcctcccagatgggcacg gagcctagcccctccctggatgctgaaggcctggtccaggagacagaggacctgtccccg tcgtcacccagcctacagcggcctcaggagcaggcgaccacacggaagttctccctgggg tgccgtgggggctacgcaggggtggcgggctacggtacctttgcctttgggggggacgcc ggtggcatgctggggcagggccccatgtgggccaagatgacctgggccgtctctcagtcc tcrgaggagcaggatgaggcagcgaccgagagcccaccgccccaggccagcacagcgcct gcacccgagggcgacggaaccctccggagggcctcccaggagctgagctcgtgggaagac atcggtgggrgctctcaggtgtcgctcgtacagatccaggacctgtccagggacccagaa gcagcagacaccgtgtccctggacatctcagaggtggatcctgcctacctcaatctgtct gatctgtatgacatcaagtatctcccatttgagttcatgatctttaggaagatccccaag ccggtggagccagagcgtccatcctcccctgagtctgaggctggggaggagctggctgag ctcccagaggctgcgtggccctsgccagccagcctggagatcacagaggagccagaggac atggaggccctgctcgggaaagctgccggcggcaggaagcgcaagtggtcacccccttcg ggcagtctcttccacttccctggaaggcactcacttctggaggagcccacagagctgggg ctacgccagagggtgaaggcctcggtagcccacatctcccgcctcctgaggggcaggcct gaaggtctggagaaggagagtcctccccggaagaaggcaggccttgcttccttccgcctg aagagcaaggaccgagcaccgtcgttcctaagggagctctcggatgagacggtggttctg ggccagtctgtgactctggcctgccaggtggtggcccarccagctgcacaggccacctgg agtaaagatggggctcttcttgagagcagcagccgcctcctcatctcctctacgctcaag aacttccagcttttgaccatcctggtggtgactgctgaggacctcggcatgtacacgtgc agtgtgagcaatgcgctggggacggcggccactacggccatcctccggaaggcagagcgc ccctcttcctcgccacggccggacattggggaggtacatgcggacggggtgctgctggtc tggaagcctgtggagtcatacggccctgtgacgtacattgtgcagtgcagcctggaaggc ggcagctggagcacgctggcctcggacgtctttgactgctgctacctcacaggaaagctt tctcggggtggggcgtacaccttccggacggcctgcgtcagcaaggcgggcatgggcccc tacagcagcccctcggagcaggtcctcctgggagggcccagccgcctggcctctgaagag gagagtggtgccacggggccggcccggcccctgcccagcatgcagaccttcgccttccag acgcagatgagaaggggccgcttcagcgtggtgcggcagtgccgggagaaggccagtggg cgcatgctggctgccaagatcgtgccctaccaccccgcggacagggctgctgtgctgcgg gagtacgaggccctcaagagcctgcgccacccacacctggcgcagctgcaggctgcctac ctcagccccaggcacctggtcctcatcttggagctgtgctccgggcctgagcttctcccc tgtctggccgagagggcctcctactcggaatcagaggtgaaggactatctgtggcagata ctaagcgccacccagtacctgcatgcccagggtatcctgcatctagacctcaggtcggag aacatgattgtcacagagtataacctgctcaaggtcatcgacttcggaaacgcccagagt ttggcccaggagagggtcctgccctcagagagattcaaggactacatggagaccatggct ccggagctcctggagggccagggcgctgtcgcgcagactgacatctgggccataggtgtt acagccttcatcatgttgagcgctgagtacccggtgaacggtgagggaacgcgagacacg cagaagggcctgcgcaaggggctcatccagctgagccgctgctatgccgggctgtctggg ggcgctgtggccttcctccgaagcacactgtgtgtgcacccctgggtccggccgtgtgca tccagctgcctgcagagcccgtggctgacggaggagggcccagccagctcccagcccgcg gcggtgaccttcccgaccactggtctgcgcgtctttgtgcgagagcgcgaaaagaggcgg gcactgctgtacaagaaacacaacctggcccaagtgcgctga

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