Bos indicus (zebu cattle): 109561589
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Entry
109561589 CDS
T04792
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00230
Purine metabolism
biu01100
Metabolic pathways
biu04024
cAMP signaling pathway
biu04928
Parathyroid hormone synthesis, secretion and action
biu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
109561589 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
109561589 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
109561589 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
109561589 (PDE4A)
Enzymes [BR:
biu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
109561589 (PDE4A)
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
109561589
NCBI-ProteinID:
XP_019819707
UniProt:
A0A6P5C3D7
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Position
7:13421683..13448440
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AA seq
813 aa
AA seq
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MXSSAAPRVRPRPPALALPPAGPESLVHFSFSEEDTCWYPPGRSVSLEAENGPTPSPGRS
PLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKRNEVEIP
SPTIKDREKQQAPRQRPCQQPPAPGPQLQPMSQITGVKKLMHSSSLNDSSMPRFGVKTDQ
EERLAQELENLNKWGLNIFRVSDYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLT
LEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVS
NQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKRQRQSLRKMVIDMV
LATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLEL
YRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLV
HPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPGGPGHPPPPDKFQFELTLDEEEEEEV
CTAPGAVAIQELYMAQDASPPEDPLEVDGQDPSAEVEIEEMYLTRQVDSTGSVAAGQDVS
VPQGASVDVCVGCRNIPALSPNSLAPLALRTPPPPEDDPGLLGLPSMAAEVGAQKEHQAA
KRACCACTGTAGEDPTPGALPAPGAWGSAGGPT
NT seq
2442 nt
NT seq
+upstream
nt +downstream
nt
atgygctccagtgcggcaccccgggtccggccccggccccctgccctggcactgcctccc
gcgggccctgagtcactggtccacttctccttcagcgaagaggacacctgttggtaccct
ccaggcagatctgtcagcttggaggcggagaatggaccgacaccgtcgccaggccgcagc
ccgctggactcgcaggcgagcccgggcctcgtgctgcatgctggtgcggccaccagccag
cgccgggagtcgtttctctaccgctcagacagygactatgacatgtcacccaagaccatg
tcccggaactcgtcggtcaccagcgaggcgcatgcagaggacctcatcgtcacgccgttt
gcccaggtgctggccagtctccggagcgttcgcagcaacttctccctcctgaccaatgtg
cccattcccagcaacaagcggtccccgctgggcggcccaacccccgtctgcaaggccacg
ctatcagaggagacgtgtcagcagttggcccgagagacactggaggagctggactggtgt
ctggagcagctggaaaccatgcagacctatcgctccgtcagcgagatggcttcccacaag
ttcaagaggatgctaaaccgtgaactcacacacctgtcagagatgagcaggtcaggaaac
caggtctctgagtacatctccaccacattcctggacaagcggaatgaagtggagatccca
tcacccacgatcaaagatcgggagaaacagcaagcgccacggcagagaccttgccagcag
cccccggcccctgggccacagcttcagcccatgtctcagataaccggagtgaagaagctg
atgcatagcagcagcctcaacgattccagcatgccccgctttggtgtgaagactgatcaa
gaggaacgcctagcccaagaactggaaaacctgaacaagtggggcctgaacatctttcgc
gtgtcagattacgctggggggcgttccctcagctgtatcatgtacacaatattccaggag
cgggacctgctgaagaagttccgcatcccggtggacactatggtgacatacatgctgacc
ctagaggaccactaccacccggatgtggcttaccacaacagcctgcacgcagccgacgtg
ctgcagtccacccatgtgctgctggccacacctgcgttggatgccgtgtttacggacctg
gagattctcgctgccctcttcgcggctgccatccacgacgtggaccaccctggagtctcc
aatcagttcctcattaacaccaattcagaactggcgctcatgtacaacgacgagtcggtg
ctggaaaatcaccacctggccgtgggcttcaagctgctgcaggaagacaactgtgacatc
ttccagaaccttggcaagcgccagcggcagagcctgcgcaagatggtcatcgacatggtg
ctggccacggatatgtccaagcacatgaccctcctggctgacctgaagaccatggtggag
actaagaaagtgaccagctcaggggtcctcttgctggataactattccgaccgcatccag
gttctacggaacatggtgcactgcgcagaccttagcaaccccaccaagccgctggagctt
taccgccagtggactgaccgcatcatggccgagttcttccagcagggcgaccgtgaacgt
gagcgaggcatggagatcagtcccatgtgcgacaagcacacagcctcagtggagaagtct
caggtgggtttcattgactatatcgtacacccgctgtgggagacgtgggctgacttggtc
cacccagatgcccaagagatcctggacactctggaagacaaccgggactggtactacagc
gccattcggcagagcccctcgccaccccccgaggaggagcctgggggaccgggccacccc
ccaccacctgataagttccagttcgagctgacgctggacgaggaagaggaggaggaggtg
tgcactgccccgggtgcggttgcaattcaggaattgtacatggcccaggatgcctcccca
cctgaagaccctttggaagttgatggccaggatccatctgcggaggtggagatagaggaa
atgtacttgacccggcaagtggactccacaggtagtgtggcagctggccaggacgtgtcc
gtgccccaaggcgcgtccgtggatgtctgtgtgggctgccgcaacatccctgccctgtct
cctaatagccttgctccgcttgccttgaggacaccgccccctccagaggacgacccgggc
cttctgggcctcccctccatggcagccgaggtgggggcccaaaaagagcatcaggctgcc
aagagggcatgctgtgcctgcacggggacagccggcgaggatcccactcctggagcgctt
ccagctcccggagcttgggggtcagctggtggccctacctga
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