Bos indicus (zebu cattle): 109562906
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Entry
109562906 CDS
T04792
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu01521
EGFR tyrosine kinase inhibitor resistance
biu04062
Chemokine signaling pathway
biu04081
Hormone signaling
biu04148
Efferocytosis
biu04151
PI3K-Akt signaling pathway
biu04217
Necroptosis
biu04550
Signaling pathways regulating pluripotency of stem cells
biu04630
JAK-STAT signaling pathway
biu04658
Th1 and Th2 cell differentiation
biu04659
Th17 cell differentiation
biu04725
Cholinergic synapse
biu04917
Prolactin signaling pathway
biu04920
Adipocytokine signaling pathway
biu04933
AGE-RAGE signaling pathway in diabetic complications
biu04935
Growth hormone synthesis, secretion and action
biu05140
Leishmaniasis
biu05145
Toxoplasmosis
biu05152
Tuberculosis
biu05161
Hepatitis B
biu05164
Influenza A
biu05167
Kaposi sarcoma-associated herpesvirus infection
biu05168
Herpes simplex virus 1 infection
biu05200
Pathways in cancer
biu05207
Chemical carcinogenesis - receptor activation
biu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
biu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
109562906 (JAK2)
04151 PI3K-Akt signaling pathway
109562906 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
109562906 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109562906 (JAK2)
09143 Cell growth and death
04217 Necroptosis
109562906 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
109562906 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
109562906 (JAK2)
04659 Th17 cell differentiation
109562906 (JAK2)
04062 Chemokine signaling pathway
109562906 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
109562906 (JAK2)
04917 Prolactin signaling pathway
109562906 (JAK2)
04935 Growth hormone synthesis, secretion and action
109562906 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
109562906 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109562906 (JAK2)
05207 Chemical carcinogenesis - receptor activation
109562906 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
109562906 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
109562906 (JAK2)
05164 Influenza A
109562906 (JAK2)
05168 Herpes simplex virus 1 infection
109562906 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
109562906 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
109562906 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
109562906 (JAK2)
05140 Leishmaniasis
109562906 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109562906 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
109562906 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109562906 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
biu01001
]
109562906 (JAK2)
Enzymes [BR:
biu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109562906 (JAK2)
Protein kinases [BR:
biu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109562906 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
109562906
NCBI-ProteinID:
XP_019821552
UniProt:
A0A6P5C7W4
LinkDB
All DBs
Position
8:complement(41547429..41669857)
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSTSPVHQNGDISGNANSVKQIDPVLQVYLYHSLGNAEGDYLQFLTG
EYVAEEICIAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRQNVLYRIRFYF
PYWYCNGSNRTYRHGIARGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKNQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDISIKQANQEGANESRIVTIHKQDGKSLEIELKSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGIRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLILNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRHNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIDKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLAVRVDQIRDNMTG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccacatcccctgtacat
cagaatggtgatatttctggaaatgctaactctgtgaagcaaatagatccagtcctacag
gtctatctttatcattcccttgggaacgctgagggggattatctgcagtttctaactgga
gagtatgttgctgaagagatctgtattgctgcttctaaagcttgtggaatcacacctgta
tatcacagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccatatagatgaatcaaccaggcaaaacgtactctacagaatcagattttacttc
ccttactggtattgtaatggcagcaacagaacctatcgacatggaatagctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttacatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaaaaatcaaaccccactggacatc
tatagctctatcagctacaagacatttttgccaaaatgtgttcgagcaaagatccaagag
tatcatattttgacaaggaagagaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttgtattgtgatttt
cctgatattattgatatcagtattaaacaagcaaatcaagaaggcgcaaatgaaagcaga
attgtaactattcataagcaagatggtaaaagtctagaaattgagcttaagtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgctatcagtaaactgaagaaaacaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagcgagaaaatgttattgaatataagcactgtttgattaccaaaaatgagaatgga
gaatacaacctcagtggtactaagaagaacttcagtaatcttaaagatcttctgaattgc
taccagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagacaaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaactttacaaaggcataataatgtgaaccaaatggtgttccacaaaatt
agaaatgaagatttggtatttaatgaaagccttggccaaggaacttttacaaaaattttt
aaaggtataagaagagaaataggagactatggtcagctgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctgattttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcactagatacgtatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcgccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaagacatcctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaacctggcaacagacaaatggagttttggt
accacattgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaa
agaaaactacagttttatgaagataggcaccagcttcctgcgccaaagtggacagaatta
gcaaatcttattaataattgcatggattatgaaccagattttaggccttctttcagagcc
attataagagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaataggtgccctaggattttctggtgcttttgaagaccgagac
cctacacaatttgaagaaagacacttgaaatttctacagcaacttggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtggct
gtgaaaaagctccagcacagtactgaagagcacctcagagacttcgaaagagaaattgaa
atccttaaatccttgcagcatgacaacattgtaaagtacaaaggagtctgctacagtgct
ggccggcataatctaagattaattatggagtatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttctgcaatacacatctcagata
tgcaaggggatggaatatcttggtacaaaaagatatatccacagggatctggcaacaagg
aatatattagtggagaatgaaaacagagttaaaataggagattttggattaaccaaagtc
ttgccacaagacaaagagtactacaaagtgaaagagcctggtgaaagtcccatattctgg
tatgcaccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgacaagagtaaaagcccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgttccatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatatatgtg
attatgacagaatgctggaacaataatgtaaaccagcgcccctctttcagagacctagca
gttcgagttgatcaaataagggacaacatgactggatga
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