Bos indicus (zebu cattle): 109564655
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Entry
109564655 CDS
T04792
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00230
Purine metabolism
biu01100
Metabolic pathways
biu04927
Cortisol synthesis and secretion
biu04934
Cushing syndrome
biu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
109564655 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
109564655 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
109564655 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
109564655 (PDE8B)
Enzymes [BR:
biu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
109564655 (PDE8B)
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GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF3880
DUF4194
Motif
Other DBs
NCBI-GeneID:
109564655
NCBI-ProteinID:
XP_019823639
UniProt:
A0A6P5CED9
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Position
10:7925184..8180611
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AA seq
779 aa
AA seq
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MDPPNAGQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYSCNIARTPE
SALECFLDKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHAVILAVVSQASGNYEEASV
LPLLHAGFNRRFMENSSIIACYNELIQIEHGEVLSQFKLRACNSVFTALDHCHEAIEITS
DDHVIQYVNPAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYY
ARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCSTDKNKQILKIHRDSGDNSQTESH
SFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQEN
SPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKN
VHQSHSHLAMPGTITDVPPSVAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGV
CEFLHCSETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEV
AALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFK
NIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIDGSDCECSPPGKNFP
ENQTLIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNT
CSIPKSQISFIDYFITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2340 nt
NT seq
+upstream
nt +downstream
nt
atggaccctccgaacgccggccaggtttcttctgcggaggtacgcatcgggcccatgaga
ttgacacaggatcctatccaggttttgctcatctttgcaaaggaagatagtcagagtgat
ggattctggtgggcctgtgacagagccggttacagctgcaatattgctcggactccagag
tcagccctggaatgctttctagataaacatcatgagattattgtaatcgatcacagacag
actcgaaacttcgatgcagaagcagtgtgcaggtcaatccgggctacgaacccctcggag
cacgcagtgatcctygccgtggtctcacaagcatccggcaactatgaagaggcctctgtg
ctccctcttctgcacgcgggcttcaacaggagatttatggagaacagcagcataatcgct
tgctacaatgaactgattcaaatagaacatggggaagttctctcacagttcaaattaagg
gcctgtaattcagtgtttacagcattagaccactgtcacgaagccatagaaatcacaagc
gatgaccacgtgatccagtatgtcaacccagccttcgagaggatgatgggctaccacaaa
ggcgaactgctggggaaagaactcgccgagctgcccaaaagcgacaagaaccgggcggac
cttctcgacaccatcaacacctgcatcaagaagggcaaggagtggcagggcgtctactac
gccagacggaaatccggcgacagcatccagcagcacgtgaagatcacaccagtgatcggc
caaggagggaagatcaggcatttcgtctccctcaagaaactgtgttgtagcactgacaaa
aacaagcagattctcaagattcatcgtgattcaggagacaattctcagacagagtctcat
tcattcagatacaagaacaggaggaaagagtccattgatgtgaaatcaatatcatctcga
ggcagtgatgcaccaagtctgcagaaccgtcgctacccatccatggcgcggatccactcc
atgaccattgaggctcccatcacgaaggttataaatataatcaacgcagcccaagaaaac
agtcctgtcacagtggcagaagccttggacagagttttagaaattttacgaactacggaa
ctgtactcccctcagctsggtaccaaagatgaagatccccacaccagcgacctcgtggga
gggctgatgactgatggcttgagaaggttgtcaggaaacgagtacgtgttcactaagaay
gtacaccagagtcatagtcaccttgcaatgccaggaaccatcaccgacgtgcccccttcc
gtcgcccaactacttgacaatgaggaaagctgggagttcaacatctttgaactggaagct
gtgacgcacaaaaggccattggtttacctgggcttgaaagttttctcccggtttggagta
tgtgaattcctacactgttctgaaactactcttcgggcctggctccaggtgatcgaagcc
aactaccactcttccaacgcttaccacaactccacccacgccgctgacgtcctgcacgcc
acagccttcttcctcggcaaggagagagtgaagggaagcttggatcagctggacgaggtg
gccgccctgatcgctgccacagtccacgacgtggaccacccgggaaggaccaactctttc
ctgtgcaacgcgggcagtgagctcgctgtgctctataatgacaccgctgtcttggagagt
caccacacagccctggccttccagctcacggtcaaggacagcaaatgcaacattttcaag
aatatcgacaggaaccattatcgaacactgcgccaagctattatcgacatggttttagca
acagagatgacaaaacactttgaacatgtgaacaaatttgtgaacagcattaacaagcca
atggcagctgagattgacggcagcgactgcgagtgcagccctccygggaagaacttccct
gagaaccagaccctgatcaagcgcatgatgattaagtgtgcggaygtagccaacccctgc
cgccccctggacctgtgcattgaatgggctgggaggatctctgaggagtactttgcgcag
acggatgaagagaagagacaggggctacccgtagtgatgccagtgtttgaccggaatacc
tgtagcatccccaagtcccaaatctcctttattgactacttcataacagacatgtttgat
gcttgggatgcctttgcacacctgccaacgctgatgcaacatttggctgataactacaaa
cactggaagacattagatgacctaaagtgcaaaagtctgaggcttccatctgacagttaa
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