Bos indicus (zebu cattle): 109572496
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Entry
109572496 CDS
T04792
Symbol
AKT2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu01521
EGFR tyrosine kinase inhibitor resistance
biu01522
Endocrine resistance
biu01524
Platinum drug resistance
biu04010
MAPK signaling pathway
biu04012
ErbB signaling pathway
biu04014
Ras signaling pathway
biu04015
Rap1 signaling pathway
biu04022
cGMP-PKG signaling pathway
biu04024
cAMP signaling pathway
biu04062
Chemokine signaling pathway
biu04066
HIF-1 signaling pathway
biu04068
FoxO signaling pathway
biu04071
Sphingolipid signaling pathway
biu04072
Phospholipase D signaling pathway
biu04140
Autophagy - animal
biu04150
mTOR signaling pathway
biu04151
PI3K-Akt signaling pathway
biu04152
AMPK signaling pathway
biu04210
Apoptosis
biu04211
Longevity regulating pathway
biu04213
Longevity regulating pathway - multiple species
biu04218
Cellular senescence
biu04261
Adrenergic signaling in cardiomyocytes
biu04370
VEGF signaling pathway
biu04371
Apelin signaling pathway
biu04380
Osteoclast differentiation
biu04510
Focal adhesion
biu04517
IgSF CAM signaling
biu04518
Integrin signaling
biu04550
Signaling pathways regulating pluripotency of stem cells
biu04611
Platelet activation
biu04613
Neutrophil extracellular trap formation
biu04620
Toll-like receptor signaling pathway
biu04625
C-type lectin receptor signaling pathway
biu04630
JAK-STAT signaling pathway
biu04660
T cell receptor signaling pathway
biu04662
B cell receptor signaling pathway
biu04664
Fc epsilon RI signaling pathway
biu04666
Fc gamma R-mediated phagosome formation
biu04668
TNF signaling pathway
biu04722
Neurotrophin signaling pathway
biu04725
Cholinergic synapse
biu04728
Dopaminergic synapse
biu04810
Regulation of actin cytoskeleton
biu04910
Insulin signaling pathway
biu04914
Progesterone-mediated oocyte maturation
biu04915
Estrogen signaling pathway
biu04917
Prolactin signaling pathway
biu04919
Thyroid hormone signaling pathway
biu04920
Adipocytokine signaling pathway
biu04922
Glucagon signaling pathway
biu04923
Regulation of lipolysis in adipocytes
biu04926
Relaxin signaling pathway
biu04929
GnRH secretion
biu04931
Insulin resistance
biu04932
Non-alcoholic fatty liver disease
biu04933
AGE-RAGE signaling pathway in diabetic complications
biu04935
Growth hormone synthesis, secretion and action
biu04936
Alcoholic liver disease
biu04973
Carbohydrate digestion and absorption
biu05010
Alzheimer disease
biu05017
Spinocerebellar ataxia
biu05132
Salmonella infection
biu05135
Yersinia infection
biu05142
Chagas disease
biu05145
Toxoplasmosis
biu05152
Tuberculosis
biu05160
Hepatitis C
biu05161
Hepatitis B
biu05162
Measles
biu05163
Human cytomegalovirus infection
biu05164
Influenza A
biu05165
Human papillomavirus infection
biu05166
Human T-cell leukemia virus 1 infection
biu05167
Kaposi sarcoma-associated herpesvirus infection
biu05168
Herpes simplex virus 1 infection
biu05169
Epstein-Barr virus infection
biu05170
Human immunodeficiency virus 1 infection
biu05200
Pathways in cancer
biu05205
Proteoglycans in cancer
biu05207
Chemical carcinogenesis - receptor activation
biu05208
Chemical carcinogenesis - reactive oxygen species
biu05210
Colorectal cancer
biu05211
Renal cell carcinoma
biu05212
Pancreatic cancer
biu05213
Endometrial cancer
biu05214
Glioma
biu05215
Prostate cancer
biu05218
Melanoma
biu05220
Chronic myeloid leukemia
biu05221
Acute myeloid leukemia
biu05222
Small cell lung cancer
biu05223
Non-small cell lung cancer
biu05224
Breast cancer
biu05225
Hepatocellular carcinoma
biu05226
Gastric cancer
biu05230
Central carbon metabolism in cancer
biu05231
Choline metabolism in cancer
biu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
biu05415
Diabetic cardiomyopathy
biu05417
Lipid and atherosclerosis
biu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109572496 (AKT2)
04012 ErbB signaling pathway
109572496 (AKT2)
04014 Ras signaling pathway
109572496 (AKT2)
04015 Rap1 signaling pathway
109572496 (AKT2)
04370 VEGF signaling pathway
109572496 (AKT2)
04371 Apelin signaling pathway
109572496 (AKT2)
04630 JAK-STAT signaling pathway
109572496 (AKT2)
04668 TNF signaling pathway
109572496 (AKT2)
04066 HIF-1 signaling pathway
109572496 (AKT2)
04068 FoxO signaling pathway
109572496 (AKT2)
04072 Phospholipase D signaling pathway
109572496 (AKT2)
04071 Sphingolipid signaling pathway
109572496 (AKT2)
04024 cAMP signaling pathway
109572496 (AKT2)
04022 cGMP-PKG signaling pathway
109572496 (AKT2)
04151 PI3K-Akt signaling pathway
109572496 (AKT2)
04152 AMPK signaling pathway
109572496 (AKT2)
04150 mTOR signaling pathway
109572496 (AKT2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
109572496 (AKT2)
04518 Integrin signaling
109572496 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109572496 (AKT2)
09143 Cell growth and death
04210 Apoptosis
109572496 (AKT2)
04218 Cellular senescence
109572496 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
109572496 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
109572496 (AKT2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109572496 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109572496 (AKT2)
04613 Neutrophil extracellular trap formation
109572496 (AKT2)
04620 Toll-like receptor signaling pathway
109572496 (AKT2)
04625 C-type lectin receptor signaling pathway
109572496 (AKT2)
04660 T cell receptor signaling pathway
109572496 (AKT2)
04662 B cell receptor signaling pathway
109572496 (AKT2)
04664 Fc epsilon RI signaling pathway
109572496 (AKT2)
04666 Fc gamma R-mediated phagosome formation
109572496 (AKT2)
04062 Chemokine signaling pathway
109572496 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
109572496 (AKT2)
04922 Glucagon signaling pathway
109572496 (AKT2)
04923 Regulation of lipolysis in adipocytes
109572496 (AKT2)
04920 Adipocytokine signaling pathway
109572496 (AKT2)
04929 GnRH secretion
109572496 (AKT2)
04915 Estrogen signaling pathway
109572496 (AKT2)
04914 Progesterone-mediated oocyte maturation
109572496 (AKT2)
04917 Prolactin signaling pathway
109572496 (AKT2)
04926 Relaxin signaling pathway
109572496 (AKT2)
04935 Growth hormone synthesis, secretion and action
109572496 (AKT2)
04919 Thyroid hormone signaling pathway
109572496 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
109572496 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
109572496 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
109572496 (AKT2)
04728 Dopaminergic synapse
109572496 (AKT2)
04722 Neurotrophin signaling pathway
109572496 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
109572496 (AKT2)
09149 Aging
04211 Longevity regulating pathway
109572496 (AKT2)
04213 Longevity regulating pathway - multiple species
109572496 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109572496 (AKT2)
05205 Proteoglycans in cancer
109572496 (AKT2)
05207 Chemical carcinogenesis - receptor activation
109572496 (AKT2)
05208 Chemical carcinogenesis - reactive oxygen species
109572496 (AKT2)
05230 Central carbon metabolism in cancer
109572496 (AKT2)
05231 Choline metabolism in cancer
109572496 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
109572496 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
109572496 (AKT2)
05212 Pancreatic cancer
109572496 (AKT2)
05225 Hepatocellular carcinoma
109572496 (AKT2)
05226 Gastric cancer
109572496 (AKT2)
05214 Glioma
109572496 (AKT2)
05221 Acute myeloid leukemia
109572496 (AKT2)
05220 Chronic myeloid leukemia
109572496 (AKT2)
05218 Melanoma
109572496 (AKT2)
05211 Renal cell carcinoma
109572496 (AKT2)
05215 Prostate cancer
109572496 (AKT2)
05213 Endometrial cancer
109572496 (AKT2)
05224 Breast cancer
109572496 (AKT2)
05222 Small cell lung cancer
109572496 (AKT2)
05223 Non-small cell lung cancer
109572496 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
109572496 (AKT2)
05170 Human immunodeficiency virus 1 infection
109572496 (AKT2)
05161 Hepatitis B
109572496 (AKT2)
05160 Hepatitis C
109572496 (AKT2)
05164 Influenza A
109572496 (AKT2)
05162 Measles
109572496 (AKT2)
05168 Herpes simplex virus 1 infection
109572496 (AKT2)
05163 Human cytomegalovirus infection
109572496 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
109572496 (AKT2)
05169 Epstein-Barr virus infection
109572496 (AKT2)
05165 Human papillomavirus infection
109572496 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
109572496 (AKT2)
05135 Yersinia infection
109572496 (AKT2)
05152 Tuberculosis
109572496 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
109572496 (AKT2)
05142 Chagas disease
109572496 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
109572496 (AKT2)
05017 Spinocerebellar ataxia
109572496 (AKT2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109572496 (AKT2)
05418 Fluid shear stress and atherosclerosis
109572496 (AKT2)
05415 Diabetic cardiomyopathy
109572496 (AKT2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109572496 (AKT2)
04932 Non-alcoholic fatty liver disease
109572496 (AKT2)
04931 Insulin resistance
109572496 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
109572496 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109572496 (AKT2)
01524 Platinum drug resistance
109572496 (AKT2)
01522 Endocrine resistance
109572496 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
biu01001
]
109572496 (AKT2)
Enzymes [BR:
biu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109572496 (AKT2)
Protein kinases [BR:
biu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
109572496 (AKT2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
PH_20
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
109572496
NCBI-ProteinID:
XP_019834891
UniProt:
A0A6P5D9I1
LinkDB
All DBs
Position
18:complement(49274058..49320780)
Genome browser
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGDDPM
DYKCGSPSDSSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITVTPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaggtgtctgtcatcaaagaaggctggctccataagcgcggtgaatatatcaag
acctggcggccccggtacttcctgctgaagagcgacggctccttcattggctataaggag
cggcctgaggcccccgaccagaccctgccccccttaaacaacttctctgtcgcagaatgc
cagctgatgaagaccgagagacctcggcccaataccttcgtcattcgctgtctgcagtgg
accacagtcatcgagaggaccttccatgttgactccccagacgagagggaagagtggatg
cgggccatccagatggttgccaacagcctcaagcagaggggtccaggggacgaccccatg
gactacaagtgtggctcccccagcgactcttctgcggccgaggagatggaggtggcagtt
agcaaggcgcgggccaaggtgaccatgaatgacttcgactatctcaaactcctgggcaaa
ggcacctttggcaaggtcatcctggtgcgggagaaggccactggccgctactatgccatg
aagatcctgcggaaggaggtgatcatcgccaaggatgaagtcgcccacacggtcaccgag
agccgggtcctgcagaacaccaggcacccgttcctcaccgcgctgaagtacgccttccag
acacacgaccgcctgtgcttcgtgatggagtacgccaacggcggcgagctgttcttccac
ttgtcccgggagcgtgtcttcacagaggagcgggcccgcttttatggagcagagatcgtc
tcagccctggagtacctgcactcgcgggacgtggtgtaccgcgacatcaagctggaaaac
ctcatgctggacaaggacggscacatcaagatcactgacttcggcctgtgcaaggagggc
atcagcgacggggccaccatgaagaccttttgtgggacccctgagtacctggcgcccgag
gtgctggaggacaacgactayggccgggcggtggactggtgggggctgggtgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggatcacgagcgcctcttcgag
ctcatyctcatggaggagatccgcttcccgcgcacgctcagccctgaggccaagtccctg
cttgctgggctgcttaagaaggaccctaagcagaggctcggcggagggcccagtgacgcc
aaggaggtcatggagcacaggttcttccttagtatcaactggcaggacgtggtccagaag
aagctcctgccacccttcaagcctcaggtcacgtctgaggtcgacacaaggtactttgac
gacgagttcaccgcccagtccatcacagtcacgcccccggaccgctatgacagcctgggc
tcactggagctggaccagcggacgcacttcccccagttctcctattcggccagcatccga
gagtga
DBGET
integrated database retrieval system