Bos indicus (zebu cattle): 109573971
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Entry
109573971 CDS
T04792
Symbol
ERBB2
Name
(RefSeq) LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu01521
EGFR tyrosine kinase inhibitor resistance
biu01522
Endocrine resistance
biu01524
Platinum drug resistance
biu04010
MAPK signaling pathway
biu04012
ErbB signaling pathway
biu04020
Calcium signaling pathway
biu04066
HIF-1 signaling pathway
biu04151
PI3K-Akt signaling pathway
biu04510
Focal adhesion
biu04520
Adherens junction
biu04530
Tight junction
biu05200
Pathways in cancer
biu05205
Proteoglycans in cancer
biu05206
MicroRNAs in cancer
biu05212
Pancreatic cancer
biu05213
Endometrial cancer
biu05215
Prostate cancer
biu05219
Bladder cancer
biu05223
Non-small cell lung cancer
biu05224
Breast cancer
biu05226
Gastric cancer
biu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109573971 (ERBB2)
04012 ErbB signaling pathway
109573971 (ERBB2)
04066 HIF-1 signaling pathway
109573971 (ERBB2)
04020 Calcium signaling pathway
109573971 (ERBB2)
04151 PI3K-Akt signaling pathway
109573971 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109573971 (ERBB2)
04520 Adherens junction
109573971 (ERBB2)
04530 Tight junction
109573971 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109573971 (ERBB2)
05206 MicroRNAs in cancer
109573971 (ERBB2)
05205 Proteoglycans in cancer
109573971 (ERBB2)
05230 Central carbon metabolism in cancer
109573971 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
109573971 (ERBB2)
05226 Gastric cancer
109573971 (ERBB2)
05219 Bladder cancer
109573971 (ERBB2)
05215 Prostate cancer
109573971 (ERBB2)
05213 Endometrial cancer
109573971 (ERBB2)
05224 Breast cancer
109573971 (ERBB2)
05223 Non-small cell lung cancer
109573971 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109573971 (ERBB2)
01524 Platinum drug resistance
109573971 (ERBB2)
01522 Endocrine resistance
109573971 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
biu01001
]
109573971 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
biu04147
]
109573971 (ERBB2)
04090 CD molecules [BR:
biu04090
]
109573971 (ERBB2)
Enzymes [BR:
biu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
109573971 (ERBB2)
Protein kinases [BR:
biu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
109573971 (ERBB2)
Exosome [BR:
biu04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
109573971 (ERBB2)
CD molecules [BR:
biu04090
]
Proteins
109573971 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
APH
Kinase-like
CcmD
Motif
Other DBs
NCBI-GeneID:
109573971
NCBI-ProteinID:
XP_019837162
UniProt:
A0A6P5DIY1
LinkDB
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Position
19:41331372..41362898
Genome browser
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPADASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEEHYALAVLDNG
DFLESAAPAAGTAPGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTILWEDIFHKNNQLP
LKQIDTNRSRACAPCSPACKAPNCWGESSQDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCAPVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFAGDPDSNIAPLQAEQLKVFESLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFQNPHQALLHSANRPEDECVGEGLACYPLCAQGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECHPQNGSVTCFGSEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGICQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
VLLVVLVGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDMGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAAGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQPLPQHDSSPLQRYSEDPTVPLSPEADGYVAPLTCSPQPEYV
NQPEVHPQPPSPLEGPLPPPRPAGSTLERPKTLSPGKNGVVKDVFAFGAAVENPEYLAPR
GRAAPQSHPSPAFSPAFDNLYYWDQDPSERGTPPSTFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgccggccagtcccgag
acccacctggacatgctgcgccacctctaccaaggctgtcaggtggtgcagggtaacctg
gagctcacctatctgcctgctgatgccagcctctccttcctgcaggaaatccaggaggtg
cagggctatgtgctcatcgctcacaatcgagtgagtcaggtcccactgcagagactgcga
atcgtgcgaggcacccagctttttgaggaacactacgccctggccgtgctggacaatgga
gactttctggaaagtgctgcccctgctgcaggcacagccccaggagggctgcaggagctg
cagctgcgaagcctcacagagatcctcaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtgggaggatatcttccacaagaacaaccagctgccc
ctcaagcagatagacaccaaccgctcacgggcctgcgcaccctgttctccagcttgtaaa
gctcccaactgctggggagaaagttctcaggactgtcagagcttgacgcggaccgtctgt
gccagtggctgtgcccgctgtaagggcccacagcccaccgactgctgccatgagcagtgc
gctgctggctgtactggccccaagcactctgactgcctggcctgcctccacttcaaccac
agcggcatctgcgagctgcactgcccagctctggtcacctacaacacagacaccttcgag
tccatgcccaaccccgaggggcgttataccttcggtgccagctgtgtgacggcctgtcct
tacaactacctgtctacggatgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagaggtgtgagaaatgcagcaagccctgtgcccca
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgccggctgcaagaagatttttgggagcctggcgtttctgccagagagc
tttgcaggggacccagactctaacatcgccccgctgcaggctgagcagctcaaagtgttt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagcgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggaa
ctgggcagcgggctggccctcattcaccgcaacgcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccagaacccccaccaggctctgctccacagcgccaacaggcca
gaggatgagtgcgtgggcgagggcctggcctgctacccactgtgcgcccaagggcactgc
tggggtcccgggcccacccagtgcgtcaactgcagccagttccttcggggccaggaatgc
gtggaggaatgccgagtactgcaggggctcccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgtcatccccagaatggctcagtgacctgctttggctcggag
gctgaccaatgtgtggcttgtgcccactacaaggatcctcccttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagtttccagatgaggag
ggcatatgccagccatgccccatcaactgcacccactcctgtgtggacttggatgacaag
ggctgccccgccgagcagagagccagccctgtgacatccatcattgccgctgtggtgggc
gttctgctggttgtycttgtggggctggtgttcggcatcctcattaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagccyctg
acgcccagcggagcgatgcccaatcaggctcagatgcggatcttaaaagagacagagctg
aggaaggtgaaggtgctaggatctggagcttttggcaccgtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatccccgtggccatcaaggtgttgagggaaaacacatct
cccaaagccaacaaggaaatcttggacgaagcatatgtgatggctggtgtaggctcccca
tatgtgtcccgcctcctgggcatctgcctgacatccacagtgcagctggtgacacagctg
atgccctatggctgcctcctagaccacgttcgagaacaccgtgggcgcctgggctcycag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcacagggacctggccgcccggaacgtgctggtcaagagtcccaaccatgtgaag
attacagacttcgggctggctcggctgytagacattgacgagacagartaccacgcggat
gggggcaaggtgcccatcaagtggatggcattggagtccattctccggcggcggtttacc
caccagagtgacgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggagaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttagtggctgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacatggggcctgctagccccctg
gatagcaccttctaccgctcgctgctggaggatgacgacatgggygacctggtggatgcg
gaggagtacctggtaccccagcagggcttcttctgcccagaccctgccccgggtgctgca
ggcacggcccatcgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctctgaggaggagcctcccagatctccgctggcaccttccgaaggg
gcaggctctgatgtgtttgatggtgacttgggaatgggggcggccaagggactgcagccc
ctcccccaacatgactctagtcctctgcagcggtacagcgaggaccccacagtacccctt
tctcccgaggctgatggctacgttgcccccttgacctgcagcccccagccggaatatgtg
aaccagccagaggttcacccacagcccccctcacccctagagggtcctctgccgcctcct
cgacctgctggttccactctggaaaggcccaagacgctatcccctgggaagaatggggtt
gtcaaagacgtttttgcctttggggctgccgtggagaaccctgagtacttggcaccccgg
ggcagggctgcccctcagtcccacccttctccagccttcagcccagcctttgacaacctc
tattattgggaccaggacccatcagagcggggcactccacccagcacctttgaagggacc
cctacggcagagaaccctgagtacttgggtctggacatgccagtatga
DBGET
integrated database retrieval system