KEGG   Bos indicus (zebu cattle): 109576248
Entry
109576248         CDS       T04792                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu04066  HIF-1 signaling pathway
biu04120  Ubiquitin mediated proteolysis
biu05200  Pathways in cancer
biu05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:biu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    109576248 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    109576248 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109576248 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    109576248 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:biu04121]
    109576248 (VHL)
Ubiquitin system [BR:biu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul2 complex
    Target recognizing subunit
     109576248 (VHL)
SSDB
Motif
Pfam: VHL VHL_C CDC37_N
Other DBs
NCBI-GeneID: 109576248
NCBI-ProteinID: XP_019840357
UniProt: A0A6P5DTN9
LinkDB
Position
22:complement(17138962..17145573)
AA seq 193 aa
MPRKAGDAEEAEAGAEEASAEDPGAEREMEAGRLRPVLRSVNTREPSQVIFCNRSPRVVL
PVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTSDGLLVNQTELFVPSLNVDGQ
PIFANITLPVYTLKERCLQVVRSLVKPEDYRRLDIVRSLYEDLEDHPNVQKDLVRLTQEH
IESQRMAGEIEDV
NT seq 582 nt   +upstreamnt  +downstreamnt
atgccccggaaggcgggggacgcggaagaggctgaggccggcgctgaggaggcgagtgca
gaggaccccggcgccgagcgggagatggaggccgggcggctgcggccggtgctgcgctcc
gtgaacacgcgcgagccgtcccaggtcatcttctgcaaccgcagcccgcgcgtggtgctg
cccgtgtggctcaacttcgatggcgagccccagccttacccgacgctgccccccggcacg
ggccgccgcatccacagctaccgaggtcacctttggctcttccgagatgctgggacatct
gatgggcttctagttaaccaaactgagctatttgtgccatctctcaatgttgatgggcag
cctatttttgccaacatcacactgccagtgtacaccctgaaagagcggtgcctccaggtt
gtgcgaagcctggtcaagcctgaggattacaggagactggacattgtgcgatccctctac
gaagatctggaagaccatcccaatgtgcagaaggacctggtgcggctgacgcaggagcat
attgaaagccagcggatggcaggggagattgaagatgtttag

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